Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1,2-dimethyl-5-(quinoxalin-6-yl)-4-m-tolyl-1H-pyrazol-3(2H)-one
    Show/Hide
 PubChem ID
CID: 16070117
SID: 24712554
Canonical SMILES
Cc1cccc(c1)-c1c(-c2ccc3nccnc3c2)n(C)n(C)c1=O
    Show/Hide
Compound Formula C20H18N4O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3050 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 20 nM