| Compound ID |
Compound Name |
Compound Formula |
|
CP0232093
|
1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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|
C22H27N3O
|
3
|
| 1 |
EC50 = 0.1585 nM
|
|
|
| 2 |
IC50 = 0.7244 nM
|
|
|
| 3 |
IC50 = 9.772 nM
|
|
|
|
CP0438120
|
1-(N-benzyl-4-fluoroanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
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|
C28H34FN5O2
|
1
|
| 1 |
EC50 = 1.8 nM
|
|
|
|
CP0006107
|
CAS_85760-74-3
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|
C13H21N3
|
1
|
| 1 |
EC50 = 2.2 nM
|
|
|
|
CP0545311
|
oxalic acid;1-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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|
C23H28N4O5
|
3
|
| 1 |
EC50 = 8.511 nM
|
|
|
| 2 |
EC50 = 12.3 nM
|
|
|
| 3 |
IC50 = 67.61 nM
|
|
|
|
CP0239544
|
1-(N-benzylanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
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|
C28H35N5O2
|
1
|
| 1 |
EC50 = 8.7 nM
|
|
|
|
CP0036921
|
3-HYDROXYTYRAMINE HYDROCHLORIDE
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|
C8H11NO2
|
5
|
| 1 |
EC50 = 12.3 nM
|
|
|
| 2 |
EC50 = 14.79 nM
|
|
|
| 3 |
EC50 = 20.89 nM
|
|
|
| 4 |
EC50 = 91.2 nM
|
|
|
| 5 |
EC50 = 269.15 nM
|
|
|
|
CP0545204
|
1-[3-[4-(4-methylphenyl)piperazin-1-yl]propyl]-3,4-dihydroquinolin-2-one;oxalic acid
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|
C25H31N3O5
|
4
|
| 1 |
EC50 = 16.22 nM
|
|
|
| 2 |
IC50 = 109.65 nM
|
|
|
| 3 |
IC50 = 331.13 nM
|
|
|
| 4 |
IC50 = 1230.27 nM
|
|
|
|
CP0148103
|
1-[N-[(4-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
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|
C28H34FN5O2
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0545205
|
1-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]-3,4-dihydroquinolin-2-one;oxalic acid
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|
C24H28ClN3O5
|
4
|
| 1 |
EC50 = 51.29 nM
|
|
|
| 2 |
IC50 = 251.19 nM
|
|
|
| 3 |
IC50 = 380.19 nM
|
|
|
| 4 |
IC50 = 10471.29 nM
|
|
|
|
CP0423460
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-pentylurea
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|
C14H26N6OS
|
2
|
| 1 |
EC50 = 109.65 nM
|
|
|
| 2 |
Kd = 0.078 nM
|
|
|
|
CP0543300
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-benzylurea;2,2,2-trifluoroacetic acid
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|
C18H21F6N7O5S
|
2
|
| 1 |
EC50 = 676.08 nM
|
|
|
| 2 |
Kd = 0.078 nM
|
|
|
|
CP0551746
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-pentylurea;2,2,2-trifluoroacetic acid
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|
C16H25F6N7O5S
|
2
|
| 1 |
EC50 = 2238.72 nM
|
|
|
| 2 |
Kd = 0.078 nM
|
|
|
|
CP0543296
|
1-[(1R)-1-phenylethyl]-3-[N'-[3-(1H-1,2,4-triazol-5-yl)propyl]carbamimidoyl]urea;dihydrochloride
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|
C15H23Cl2N7O
|
2
|
| 1 |
EC50 = 6606.93 nM
|
|
|
| 2 |
Kd = 0.078 nM
|
|
|
|
CP0232092
|
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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|
C21H32N2O
|
2
|
| 1 |
IC50 = 6.026 nM
|
|
|
| 2 |
IC50 = 117.49 nM
|
|
|
|
CP0046420
|
CAS_3853
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|
C18H19ClN4
|
5
|
| 1 |
IC50 = 42.66 nM
|
|
|
| 2 |
IC50 = 93.33 nM
|
|
|
| 3 |
IC50 = 144.54 nM
|
|
|
| 4 |
IC50 = 162.18 nM
|
|
|
| 5 |
IC50 = 1949.84 nM
|
|
|
|
CP0573476
|
1-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl]-3,4-dihydroquinolin-2-one;oxalic acid
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|
C25H31N3O6
|
3
|
| 1 |
IC50 = 107.15 nM
|
|
|
| 2 |
IC50 = 269.15 nM
|
|
|
| 3 |
IC50 = 389.05 nM
|
|
|
|
CP0378647
|
1-[3-[4-(5-hydroxypentyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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|
C22H34N2O2
|
2
|
| 1 |
IC50 = 125.89 nM
|
|
|
| 2 |
IC50 = 151.36 nM
|
|
|
|
CP0116478
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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|
C24H30N2O
|
2
|
| 1 |
IC50 = 169.82 nM
|
|
|
| 2 |
IC50 = 575.44 nM
|
|
|
