Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_85760-74-3
    Show/Hide
 PubChem ID
CID: 54562
SID: 14822656
Canonical SMILES
CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12
    Show/Hide
Compound Formula C13H21N3
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  8
1
EC50 = 1.4 nM
   TI
   LI
   LO
   TS
2
EC50 = 2 nM
   TI
   LI
   LO
   TS
3
EC50 = 9.9 nM
   TI
   LI
   LO
   TS
4
EC50 = 11 nM
   TI
   LI
   LO
   TS
5
EC50 = 23 nM
   TI
   LI
   LO
   TS
6
Ki = 1.8 nM
   TI
   LI
   LO
   TS
7
Ki = 8.5 nM
   TI
   LI
   LO
   TS
8
Ki = 53 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 49 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2.2 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 2.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 5 nM
   TI
   LI
   LO
   TS
3
EC50 = 83 nM
   TI
   LI
   LO
   TS