Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-HYDROXYTYRAMINE HYDROCHLORIDE
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 PubChem ID
CID: 681
SID: 15170929
Canonical SMILES
NCCc1ccc(O)c(O)c1
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Compound Formula C8H11NO2
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 6.2 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 12.3 nM
   TI
   LI
   LO
   TS
2
EC50 = 14.79 nM
   TI
   LI
   LO
   TS
3
EC50 = 20.89 nM
   TI
   LI
   LO
   TS
4
EC50 = 91.2 nM
   TI
   LI
   LO
   TS
5
EC50 = 269.15 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 1.8 nM
   TI
   LI
   LO
   TS
2
EC50 = 2.2 nM
   TI
   LI
   LO
   TS
3
EC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.2 nM
2 Ki = 57 nM
3 Ki = 62 nM
4 Ki = 97 nM