Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(N-benzyl-4-fluoroanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
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 PubChem ID
CID: 155559617
Canonical SMILES
COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccc(F)cc2)CC1
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Compound Formula C28H34FN5O2
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.55 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1.8 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 340 nM
   TI
   LI
   LO
   TS
2
IC50 = 49 nM
   TI
   LI
   LO
   TS