| Compound ID |
Compound Name |
Compound Formula |
|
CP0081974
|
US10034864, Example 1
Show/Hide
|
C11H13BrFN7O4S
|
12
|
| 1 |
EC50 = 8 nM
|
|
|
| 2 |
EC50 = 13 nM
|
|
|
| 3 |
IC50 = 7 nM
|
|
|
| 4 |
IC50 = 7.1 nM
|
|
|
| 5 |
IC50 = 7.4 nM
|
|
|
| 6 |
IC50 = 10 nM
|
|
|
| 7 |
IC50 = 10.3 nM
|
|
|
| 8 |
IC50 = 11 nM
|
|
|
| 9 |
IC50 = 12.5 nM
|
|
|
| 10 |
IC50 = 16 nM
|
|
|
| 11 |
IC50 = 20 nM
|
|
|
| 12 |
IC50 = 70 nM
|
|
|
|
CP0566121
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-(2-sulfamoylethylamino)-1,2,5-oxadiazole-3-carboximidamide
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|
C11H12BrFN6O4S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0339198
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-(3-sulfamoylpropylamino)-1,2,5-oxadiazole-3-carboximidamide
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|
C12H14BrFN6O4S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0068584
|
N'-(3-bromo-4-fluorophenyl)-4-[2-(dimethylsulfamoyl)ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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|
C13H16BrFN6O4S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0341678
|
N'-(3-bromo-4-fluorophenyl)-4-[3-(dimethylsulfamoyl)propylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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|
C14H18BrFN6O4S
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0554096
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-(2-sulfamoylethoxyamino)-1,2,5-oxadiazole-3-carboximidamide
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|
C11H12BrFN6O5S
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0570390
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-3-yl]methyl]-3-(4-cyanophenyl)urea
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|
C20H16BrN5O2S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0249982
|
N'-(4-bromophenyl)-3,3-difluoro-2-oxo-1H-indole-5-sulfonohydrazide
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|
C14H10BrF2N3O3S
|
1
|
| 1 |
EC50 = 30.6 nM
|
|
|
|
CP0341677
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[2-(prop-2-ynylsulfamoyl)ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C14H14BrFN6O4S
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0570584
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(4-cyanophenyl)urea
Show/Hide
|
C20H16BrN5O2S
|
1
|
| 1 |
EC50 = 33.2 nM
|
|
|
|
CP0534337
|
N'-(4-bromophenyl)-3,3-dimethyl-2-oxo-1H-indole-5-sulfonohydrazide
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|
C16H16BrN3O3S
|
1
|
| 1 |
EC50 = 36.4 nM
|
|
|
|
CP0579401
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(4-fluorophenyl)urea
Show/Hide
|
C19H16BrFN4O2S
|
1
|
| 1 |
EC50 = 39.8 nM
|
|
|
|
CP0163136
|
N'-(3-bromo-4-fluorophenyl)-4-[2-(ethylsulfamoyl)ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C13H16BrFN6O4S
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0577768
|
2-chloro-N'-(3-chloro-4-fluorophenyl)-N-hydroxy-1,3-thiazole-5-carboximidamide
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|
C10H6Cl2FN3OS
|
1
|
| 1 |
EC50 = 47.5 nM
|
|
|
|
CP0134809
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[(1-imino-1-oxothietan-3-yl)amino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C12H12BrFN6O3S
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
|
CP0570389
|
N'-(3-bromophenyl)-N-hydroxy-5-methylthiophene-2-carboximidamide
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|
C12H11BrN2OS
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0169133
|
1-cyclohexyl-2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)ethanol
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|
C18H21FN2O
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0571154
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(2-fluorophenyl)urea
Show/Hide
|
C19H16BrFN4O2S
|
1
|
| 1 |
EC50 = 58.5 nM
|
|
|
|
CP0352012
|
N'-(3-bromo-4-fluorophenyl)-4-[(1,1-dioxothietan-3-yl)amino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C12H11BrFN5O4S
|
1
|
| 1 |
EC50 = 59 nM
|
|
|
|
CP0353563
|
N'-(3-bromophenyl)-5-chloro-N-hydroxythiophene-2-carboximidamide
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|
C11H8BrClN2OS
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0102032
|
1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol
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|
C18H22N2O
|
3
|
| 1 |
EC50 = 61 nM
|
|
|
| 2 |
IC50 = 190 nM
|
|
|
| 3 |
IC50 = 410 nM
|
|
|
|
CP0090036
|
N'-(4-bromophenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonohydrazide
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|
C13H11BrN4O3S
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0542680
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(3-fluorophenyl)urea
Show/Hide
|
C19H16BrFN4O2S
|
1
|
| 1 |
EC50 = 63.4 nM
|
|
|
|
CP0574898
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(3-cyanophenyl)urea
Show/Hide
|
C20H16BrN5O2S
|
1
|
| 1 |
EC50 = 65.2 nM
|
|
|
|
CP0369160
|
N'-(4-bromophenyl)-2-oxo-3,4-dihydro-1H-quinoline-6-sulfonohydrazide
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|
C15H14BrN3O3S
|
1
|
| 1 |
EC50 = 67 nM
|
|
|
|
CP0022060
|
N'-(4-bromophenyl)-2-oxo-1,3-dihydroindole-5-sulfonohydrazide
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|
C14H12BrN3O3S
|
1
|
| 1 |
EC50 = 67.6 nM
|
|
|
|
CP0071578
|
2-amino-N'-(4-bromophenyl)-3H-benzimidazole-5-sulfonohydrazide
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|
C13H12BrN5O2S
|
1
|
| 1 |
EC50 = 68.4 nM
|
|
|
|
CP0414492
|
N'-(3-bromo-4-fluorophenyl)-4-[(1-cyanoiminothietan-3-yl)amino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C13H11BrFN7O2S
|
1
|
| 1 |
EC50 = 73 nM
|
|
|
|
CP0534936
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(3-methylphenyl)urea
Show/Hide
|
C20H19BrN4O2S
|
1
|
| 1 |
EC50 = 73.4 nM
|
|
|
|
CP0559655
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[(1-oxothietan-3-yl)amino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C12H11BrFN5O3S
|
1
|
| 1 |
EC50 = 79 nM
|
|
|
|
CP0380102
|
N-[4-[(4-chloro-3-fluoroanilino)sulfamoyl]phenyl]acetamide
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|
C14H13ClFN3O3S
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0568783
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-3-yl]methyl]-3-(3-fluorophenyl)urea
Show/Hide
|
C19H16BrFN4O2S
|
1
|
| 1 |
EC50 = 84.4 nM
|
|
|
|
CP0541940
|
N-[4-[(4-bromoanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H14BrN3O3S
|
1
|
| 1 |
EC50 = 85 nM
|
|
|
|
CP0577926
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C19H16BrClN4O2S
|
1
|
| 1 |
EC50 = 87.5 nM
|
|
|
|
CP0071523
|
N'-(4-bromophenyl)-4-(2-oxopyrrolidin-1-yl)benzenesulfonohydrazide
Show/Hide
|
C16H16BrN3O3S
|
1
|
| 1 |
EC50 = 89.6 nM
|
|
|
|
CP0574897
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(3-chlorophenyl)urea
Show/Hide
|
C19H16BrClN4O2S
|
1
|
| 1 |
EC50 = 90.6 nM
|
|
|
|
CP0542681
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-(2-methylphenyl)urea
Show/Hide
|
C20H19BrN4O2S
|
1
|
| 1 |
EC50 = 93.1 nM
|
|
|
|
CP0136721
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-(2-sulfamoylhydrazinyl)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C9H9BrFN7O4S
|
1
|
| 1 |
EC50 = 101 nM
|
|
|
|
CP0532740
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-3-yl]methyl]-3-(4-fluorophenyl)urea
Show/Hide
|
C19H16BrFN4O2S
|
1
|
| 1 |
EC50 = 102.2 nM
|
|
|
|
CP0577767
|
N'-(3-bromophenyl)-6-chloro-N-hydroxypyridine-3-carboximidamide
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|
C12H9BrClN3O
|
1
|
| 1 |
EC50 = 104.4 nM
|
|
|
|
CP0380103
|
N'-(4-bromophenyl)benzenesulfonohydrazide
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|
C12H11BrN2O2S
|
1
|
| 1 |
EC50 = 128 nM
|
|
|
|
CP0511010
|
N-[4-[(4-bromo-3-methylanilino)sulfamoyl]phenyl]acetamide
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|
C15H16BrN3O3S
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0481637
|
N'-(4-bromophenyl)-4-cyanobenzenesulfonohydrazide
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|
C13H10BrN3O2S
|
1
|
| 1 |
EC50 = 134 nM
|
|
|
|
CP0452493
|
N'-(4-bromophenyl)-1,3-dimethyl-2-oxobenzimidazole-5-sulfonohydrazide
Show/Hide
|
C15H15BrN4O3S
|
1
|
| 1 |
EC50 = 134.9 nM
|
|
|
|
CP0418203
|
N-[4-[(4-chloroanilino)sulfamoyl]phenyl]acetamide
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|
C14H14ClN3O3S
|
1
|
| 1 |
EC50 = 142 nM
|
|
|
|
CP0387130
|
4-[2-(azetidin-1-ylsulfonyl)ethylamino]-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C14H16BrFN6O4S
|
1
|
| 1 |
EC50 = 143 nM
|
|
|
|
CP0386320
|
2-[4-[(4-bromoanilino)sulfamoyl]phenoxy]acetic acid
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|
C14H13BrN2O5S
|
1
|
| 1 |
EC50 = 152 nM
|
|
|
|
CP0386521
|
4-[(4-bromoanilino)sulfamoyl]benzoic acid
Show/Hide
|
C13H11BrN2O4S
|
1
|
| 1 |
EC50 = 172 nM
|
|
|
|
CP0357517
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-3-yl]methyl]-3-(3-cyanophenyl)urea
Show/Hide
|
C20H16BrN5O2S
|
1
|
| 1 |
EC50 = 173.2 nM
|
|
|
|
CP0458470
|
N-[4-[[4-(trifluoromethyl)anilino]sulfamoyl]phenyl]acetamide
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|
C15H14F3N3O3S
|
1
|
| 1 |
EC50 = 181 nM
|
|
|
|
CP0458471
|
3-[4-[(4-bromoanilino)sulfamoyl]phenyl]propanoic acid
Show/Hide
|
C15H15BrN2O4S
|
1
|
| 1 |
EC50 = 183 nM
|
|
|
|
CP0555185
|
N-[4-[(4-bromo-3-fluoroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H13BrFN3O3S
|
1
|
| 1 |
EC50 = 187 nM
|
|
|
|
CP0573428
|
N-[4-[(4-bromoanilino)sulfamoyl]phenyl]butanamide
Show/Hide
|
C16H18BrN3O3S
|
1
|
| 1 |
EC50 = 187 nM
|
|
|
|
CP0542679
|
5-chloro-N'-(3-chloro-4-fluorophenyl)-N-hydroxythiophene-2-carboximidamide
Show/Hide
|
C11H7Cl2FN2OS
|
1
|
| 1 |
EC50 = 191 nM
|
|
|
|
CP0549198
|
N'-(4-bromophenyl)-2-oxo-1,3,4,5-tetrahydro-1-benzazepine-7-sulfonohydrazide
Show/Hide
|
C16H16BrN3O3S
|
1
|
| 1 |
EC50 = 195 nM
|
|
|
|
CP0239834
|
N'-(4-bromophenyl)-2-oxo-1H-quinoline-6-sulfonohydrazide
Show/Hide
|
C15H12BrN3O3S
|
1
|
| 1 |
EC50 = 211.5 nM
|
|
|
|
CP0309727
|
N-[4-[(4-bromoanilino)sulfamoyl]phenyl]-3-morpholin-4-ylpropanamide
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|
C19H23BrN4O4S
|
1
|
| 1 |
EC50 = 217 nM
|
|
|
|
CP0353566
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-3-yl]methyl]-3-(4-chlorophenyl)urea
Show/Hide
|
C19H16BrClN4O2S
|
1
|
| 1 |
EC50 = 222.8 nM
|
|
|
|
CP0279122
|
1-acetyl-N'-(4-bromophenyl)-2,3-dihydroindole-5-sulfonohydrazide
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|
C16H16BrN3O3S
|
1
|
| 1 |
EC50 = 231.4 nM
|
|
|
|
CP0380104
|
MLS001171649
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|
C15H17N3O3S
|
1
|
| 1 |
EC50 = 241 nM
|
|
|
|
CP0577766
|
6-chloro-N'-(3-chloro-4-fluorophenyl)-N-hydroxypyridine-3-carboximidamide
Show/Hide
|
C12H8Cl2FN3O
|
1
|
| 1 |
EC50 = 267 nM
|
|
|
|
CP0139487
|
N'-(3-bromo-4-fluorophenyl)-4-[2-(cyclopropylmethylsulfamoyl)ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C15H18BrFN6O4S
|
1
|
| 1 |
EC50 = 268 nM
|
|
|
|
CP0163137
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[2-(2,2,2-trifluoroethylsulfamoyl)ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C13H13BrF4N6O4S
|
1
|
| 1 |
EC50 = 268 nM
|
|
|
|
CP0489196
|
2-[[4-[(3-methylanilino)sulfamoyl]benzoyl]amino]acetic acid
Show/Hide
|
C16H17N3O5S
|
1
|
| 1 |
EC50 = 271 nM
|
|
|
|
CP0569270
|
N'-(3-bromo-4-fluorophenyl)-6-chloro-N-hydroxypyridine-3-carboximidamide
Show/Hide
|
C12H8BrClFN3O
|
1
|
| 1 |
EC50 = 272 nM
|
|
|
|
CP0353564
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-2-yl]methyl]-3-[4-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H16BrF3N4O2S
|
1
|
| 1 |
EC50 = 292.8 nM
|
|
|
|
CP0555186
|
N'-(3-methylphenyl)-4-[5-(trifluoromethyl)pyridin-2-yl]oxybenzenesulfonohydrazide
Show/Hide
|
C19H16F3N3O3S
|
1
|
| 1 |
EC50 = 296 nM
|
|
|
|
CP0385815
|
N-[4-[(3,4-dichloroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H13Cl2N3O3S
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
|
CP0191728
|
N'-(4-bromophenyl)-1-methyl-2-oxo-3H-indole-5-sulfonohydrazide
Show/Hide
|
C15H14BrN3O3S
|
1
|
| 1 |
EC50 = 365.1 nM
|
|
|
|
CP0489197
|
4-bromo-N'-(4-bromophenyl)benzenesulfonohydrazide
Show/Hide
|
C12H10Br2N2O2S
|
1
|
| 1 |
EC50 = 374 nM
|
|
|
|
CP0574899
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-3-yl]methyl]-3-(3-chlorophenyl)urea
Show/Hide
|
C19H16BrClN4O2S
|
1
|
| 1 |
EC50 = 439.4 nM
|
|
|
|
CP0386321
|
methyl 3-[4-[(4-bromoanilino)sulfamoyl]phenyl]propanoate
Show/Hide
|
C16H17BrN2O4S
|
1
|
| 1 |
EC50 = 465 nM
|
|
|
|
CP0544027
|
N-[4-[(3,5-dichloroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H13Cl2N3O3S
|
1
|
| 1 |
EC50 = 508 nM
|
|
|
|
CP0566120
|
N'-(3-bromo-4-fluorophenyl)-4-hydrazinyl-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C9H8BrFN6O2
|
1
|
| 1 |
EC50 = 556 nM
|
|
|
|
CP0506998
|
N-[4-[(4-fluoroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H14FN3O3S
|
1
|
| 1 |
EC50 = 609 nM
|
|
|
|
CP0380105
|
N'-(4-bromophenyl)-4-methoxybenzenesulfonohydrazide
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|
C13H13BrN2O3S
|
1
|
| 1 |
EC50 = 640 nM
|
|
|
|
CP0570089
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-3-yl]methyl]-3-[4-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H16BrF3N4O2S
|
1
|
| 1 |
EC50 = 648.4 nM
|
|
|
|
CP0270602
|
1-cyclohexyl-2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)ethanone
Show/Hide
|
C18H19FN2O
|
1
|
| 1 |
EC50 = 725 nM
|
|
|
|
CP0353560
|
5-chloro-N'-(3-chloro-4-fluorophenyl)-N-hydroxypyridine-2-carboximidamide
Show/Hide
|
C12H8Cl2FN3O
|
1
|
| 1 |
EC50 = 727 nM
|
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|
CP0185837
|
1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanone
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
EC50 = 749 nM
|
|
|
|
CP0577028
|
1-[[5-[N'-(3-bromophenyl)-N-hydroxycarbamimidoyl]thiophen-3-yl]methyl]-3-[3-(trifluoromethyl)phenyl]urea
Show/Hide
|
C20H16BrF3N4O2S
|
1
|
| 1 |
EC50 = 1152.2 nM
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|
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CP0560897
|
N-[4-[(4-methylanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C15H17N3O3S
|
1
|
| 1 |
EC50 = 1171 nM
|
|
|
|
CP0385744
|
N-[4-[(4-cyanoanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C15H14N4O3S
|
1
|
| 1 |
EC50 = 1393 nM
|
|
|
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CP0531926
|
N-[4-[(3,5-difluoroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H13F2N3O3S
|
1
|
| 1 |
EC50 = 2229 nM
|
|
|
|
CP0385817
|
N-[4-[(3-bromo-4-fluoroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H13BrFN3O3S
|
1
|
| 1 |
EC50 = 2494 nM
|
|
|
|
CP0559992
|
3-[2-(cyclohexylamino)ethyl]-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
EC50 = 2540 nM
|
|
|
|
CP0386322
|
N-[4-[(3-chloro-4-fluoroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H13ClFN3O3S
|
1
|
| 1 |
EC50 = 2588 nM
|
|
|
|
CP0572022
|
3-[2-(propan-2-ylamino)ethyl]-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C18H19N3O2
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0416386
|
3-[2-(butylamino)ethyl]-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C19H21N3O2
|
1
|
| 1 |
EC50 = 2720 nM
|
|
|
|
CP0380106
|
N-[4-[(4-sulfamoylanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H16N4O5S2
|
1
|
| 1 |
EC50 = 3118 nM
|
|
|
|
CP0458464
|
4-cyano-N'-(3-methylphenyl)benzenesulfonohydrazide
Show/Hide
|
C14H13N3O2S
|
1
|
| 1 |
EC50 = 3404 nM
|
|
|
|
CP0525485
|
3-[2-(ethylamino)ethyl]-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
EC50 = 3580 nM
|
|
|
|
CP0420288
|
3-[2-(dimethylamino)ethyl]-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C17H17N3O2
|
1
|
| 1 |
EC50 = 4220 nM
|
|
|
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CP0532269
|
3-[2-(2,2-dimethylpropylamino)ethyl]-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
EC50 = 4530 nM
|
|
|
|
CP0572023
|
N-[2-(4,7-dioxo-5-pyridin-3-yl-1H-indol-3-yl)ethyl]-2,2-dimethylpropanamide
Show/Hide
|
C20H21N3O3
|
1
|
| 1 |
EC50 = 4600 nM
|
|
|
|
CP0527201
|
N-[2-(4,7-dioxo-5-pyridin-3-yl-1H-indol-3-yl)ethyl]benzenesulfonamide
Show/Hide
|
C21H17N3O4S
|
1
|
| 1 |
EC50 = 4920 nM
|
|
|
|
CP0473099
|
N-[2-(4,7-dioxo-5-pyridin-3-yl-1H-indol-3-yl)ethyl]benzamide
Show/Hide
|
C22H17N3O3
|
1
|
| 1 |
EC50 = 5090 nM
|
|
|
|
CP0540013
|
tert-butyl N-[2-(4,7-dioxo-5-pyridin-3-yl-1H-indol-3-yl)ethyl]carbamate
Show/Hide
|
C20H21N3O4
|
1
|
| 1 |
EC50 = 5400 nM
|
|
|
|
CP0571416
|
3-(2-aminoethyl)-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C15H13N3O2
|
1
|
| 1 |
EC50 = 6620 nM
|
|
|
|
CP0531927
|
N-[4-[(3-bromoanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H14BrN3O3S
|
1
|
| 1 |
EC50 = 7563 nM
|
|
|
|
CP0510994
|
N'-(3-methylphenyl)-4-methylsulfonylbenzenesulfonohydrazide
Show/Hide
|
C14H16N2O4S2
|
1
|
| 1 |
EC50 = 7846 nM
|
|
|
|
CP0475041
|
(3E)-3-[[4-(3-hydroxyphenyl)-1,3-thiazol-2-yl]hydrazinylidene]inden-1-one
Show/Hide
|
C18H13N3O2S
|
1
|
| 1 |
EC50 = 9171 nM
|
|
|
|
CP0436973
|
(3E)-3-[[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]hydrazinylidene]inden-1-one
Show/Hide
|
C20H17N3O3S
|
1
|
| 1 |
EC50 = 9703 nM
|
|
|
|
CP0380107
|
N-[4-[(2,4-difluoroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H13F2N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386323
|
N-[4-(anilinosulfamoyl)phenyl]acetamide
Show/Hide
|
C14H15N3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386324
|
N-[4-[(4-methoxyanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C15H17N3O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0481638
|
N-[4-[(3-fluoroanilino)sulfamoyl]phenyl]acetamide
Show/Hide
|
C14H14FN3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0102036
|
1-cyclohexyl-2-(5H-triazolo[5,1-a]isoindol-5-yl)ethanol
Show/Hide
|
C17H21N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0181074
|
1-cyclohexyl-2-(3-methyl-5H-imidazo[5,1-a]isoindol-5-yl)ethanol
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0258970
|
1-cyclohexyl-2-(5,6-dihydroimidazo[1,5-c]quinazolin-5-yl)ethanol
Show/Hide
|
C18H23N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0416387
|
3-[2-(2-phenylethylamino)ethyl]-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C23H21N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0473098
|
3-[2-(diethylamino)ethyl]-5-pyridin-3-yl-1H-indole-4,7-dione
Show/Hide
|
C19H21N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0571407
|
N-[2-(4,7-dioxo-5-pyridin-3-yl-1H-indol-3-yl)ethyl]acetamide
Show/Hide
|
C17H15N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0475042
|
3-[2-[(2E)-2-(3-oxoinden-1-ylidene)hydrazinyl]-1,3-thiazol-4-yl]benzonitrile
Show/Hide
|
C19H12N4OS
|
1
|
| 1 |
EC50 = 12520 nM
|
|
|
|
CP0460389
|
(3E)-3-[(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]inden-1-one
Show/Hide
|
C18H13N3OS
|
1
|
| 1 |
EC50 = 13260 nM
|
|
|
|
CP0436974
|
(3E)-3-[(4-cyclohexyl-1,3-thiazol-2-yl)hydrazinylidene]inden-1-one
Show/Hide
|
C18H19N3OS
|
1
|
| 1 |
EC50 = 15310 nM
|
|
|
|
CP0510342
|
(3E)-3-[[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]hydrazinylidene]inden-1-one
Show/Hide
|
C19H15N3O2S
|
1
|
| 1 |
EC50 = 17540 nM
|
|
|
|
CP0481636
|
N',2-diphenylethanesulfonohydrazide
Show/Hide
|
C14H16N2O2S
|
1
|
| 1 |
EC50 > 10 nM
|
|
|
|
CP0121711
|
N'-(3-bromo-4-fluorophenyl)-4-[2-(hydrazinesulfonyl)ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C11H13BrFN7O4S
|
1
|
| 1 |
EC50 > 800 nM
|
|
|
|
CP0339197
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[2-(hydroxysulfamoyl)ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C11H12BrFN6O5S
|
1
|
| 1 |
EC50 > 800 nM
|
|
|
|
CP0554093
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-(2-methylsulfonylhydrazinyl)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C10H10BrFN6O4S
|
1
|
| 1 |
EC50 > 800 nM
|
|
|
|
CP0555723
|
US11046649, Ex. 5
Show/Hide
|
C22H19ClF5N3
|
1
|
| 1 |
IC50 = 0.52 nM
|
|
|
|
CP0388402
|
3-chloro-N-[3-[(2S)-1-(4-chloroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
|
C21H20Cl2N2O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0422691
|
4-chloro-N-[1-[(1R,5S)-3-(6-fluoroquinolin-4-yl)-6-bicyclo[3.1.0]hexanyl]ethyl]benzamide
Show/Hide
|
C24H22ClFN2O
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0137413
|
4-chloro-N-[1-[(1R,5S)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]ethyl]benzamide
Show/Hide
|
C22H20ClF2N3O
|
1
|
| 1 |
IC50 = 0.69 nM
|
|
|
|
CP0748623
|
4-((1R,3s,5S,6r)-6-(1-(5-chloro-1H-benzo[d]imidazol-2-yl)propyl)bicyclo[3.1.0]hexan-3-yl)-6-fluoroquinoline
Show/Hide
|
C25H23ClFN3
|
1
|
| 1 |
IC50 = 0.92 nM
|
|
|
|
CP0555018
|
CHEMBL4875089
Show/Hide
|
C25H24ClFN2O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0548549
|
4-fluoro-N-[(1S,2S)-2-methyl-1-[5-(2-methylpyrimidin-4-yl)-7,8-dihydro-6H-1,5-naphthyridin-2-yl]cyclopropyl]benzamide
Show/Hide
|
C24H24FN5O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0423352
|
4-fluoro-N-[1-[5-[2-(trifluoromethyl)pyrimidin-4-yl]-7,8-dihydro-6H-1,5-naphthyridin-2-yl]cyclopropyl]benzamide
Show/Hide
|
C23H19F4N5O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0547801
|
4-fluoro-N-[1-[5-(2-methylpyrimidin-4-yl)-7,8-dihydro-6H-1,5-naphthyridin-2-yl]cyclopropyl]benzamide
Show/Hide
|
C23H22FN5O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0567324
|
cyclopropyl 5-[1-[(4-fluorophenyl)carbamoyl]cyclobutyl]-2,3-dihydroindole-1-carboxylate
Show/Hide
|
C23H23FN2O3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0570903
|
4-chloro-N-[1-[(1R,5S)-3-(7-fluoroquinolin-4-yl)oxy-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C25H24ClFN2O2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0568190
|
3,3-difluoro-N-(4-fluorophenyl)-1-[4-[4-(hydroxymethyl)-6-(trifluoromethyl)pyridin-3-yl]phenyl]cyclobutane-1-carboxamide
Show/Hide
|
C24H18F6N2O2
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0575320
|
N-(4-chlorophenyl)-1-(1-pyridin-2-yl-2,3-dihydroindol-5-yl)cyclobutane-1-carboxamide
Show/Hide
|
C24H22ClN3O
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0517047
|
4-chloro-N-[1-[(1R,5S)-3-quinolin-4-yloxy-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C25H25ClN2O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0552085
|
3-chloro-N-[4-[1-[(4-fluorophenyl)carbamoyl]cyclobutyl]phenyl]benzamide
Show/Hide
|
C24H20ClFN2O2
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0534438
|
4-chloro-N-[(1R)-1-[(1S,5R)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C23H22ClF2N3O
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0530489
|
4-fluoro-N-[(1R)-1-[5-[2-(trifluoromethyl)pyrimidin-4-yl]-7,8-dihydro-6H-1,5-naphthyridin-2-yl]ethyl]benzamide
Show/Hide
|
C22H19F4N5O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0414359
|
3,4-difluoro-N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
|
C21H19F3N2O2
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0564924
|
cyclopropyl 5-[1-[(4-chlorophenyl)carbamoyl]cyclobutyl]-2,3-dihydropyrrolo[3,2-b]pyridine-1-carboxylate
Show/Hide
|
C22H22ClN3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0423353
|
N-[1-[(1aR,7bS)-3-(2-methylpyrimidin-4-yl)-1,1a,2,7b-tetrahydrocyclopropa[h][1,5]naphthyridin-6-yl]cyclopropyl]-4-fluorobenzamide
Show/Hide
|
C24H22FN5O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0574235
|
N-(4-fluorophenyl)-3-[4-[4-(hydroxymethyl)-6-(trifluoromethyl)pyridin-3-yl]phenyl]oxetane-3-carboxamide
Show/Hide
|
C23H18F4N2O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0552086
|
3-[4-[(3-chlorobenzoyl)amino]phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide
Show/Hide
|
C23H18ClFN2O3
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0492578
|
3-chloro-4-fluoro-N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
|
C21H19ClF2N2O2
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0492580
|
3-chloro-5-fluoro-N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
|
C21H19ClF2N2O2
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0577700
|
N-(4-fluorophenyl)-3-[4-[4-methyl-6-(trifluoromethyl)pyridin-3-yl]phenyl]oxetane-3-carboxamide
Show/Hide
|
C23H18F4N2O2
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0570733
|
N-(4-chlorophenyl)-1-(1-pyridin-2-yl-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl)cyclobutane-1-carboxamide
Show/Hide
|
C23H21ClN4O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0580245
|
3-[4-(6-cyclopropyl-4-methylpyridin-3-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide
Show/Hide
|
C25H23FN2O2
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0451077
|
4-chloro-N-[1-[(1R,5S)-3-(6-fluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C23H23ClFN3O
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0576076
|
CHEMBL4866113
Show/Hide
|
C23H23ClFN3O
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0540067
|
3-chloro-N-[5-[1-[(4-fluorophenyl)carbamoyl]cyclobutyl]pyridin-2-yl]benzamide
Show/Hide
|
C23H19ClFN3O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0559005
|
cyclopropyl 5-[1-[(4-fluorophenyl)carbamoyl]cyclobutyl]-2,3-dihydropyrrolo[3,2-b]pyridine-1-carboxylate
Show/Hide
|
C22H22FN3O3
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0165127
|
CHEMBL4161733
Show/Hide
|
C24H24ClFN2O
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0570735
|
methyl (2aR,7bR)-6-[1-[(4-fluorobenzoyl)amino]cyclopropyl]-1,2,2a,7b-tetrahydrocyclobuta[b]indole-3-carboxylate
Show/Hide
|
C22H21FN2O3
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0572530
|
N-[1-[(1aR,6bR)-2-(2-methylpyrimidin-4-yl)-1a,6b-dihydro-1H-cyclopropa[b]indol-5-yl]cyclopropyl]-4-fluorobenzamide
Show/Hide
|
C24H21FN4O
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0570732
|
1-[1-(3-chlorobenzoyl)-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl]-N-(4-fluorophenyl)cyclobutane-1-carboxamide
Show/Hide
|
C25H21ClFN3O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0572932
|
N-(4-fluorophenyl)-3-[4-[4-(2-hydroxypropan-2-yl)-6-(trifluoromethyl)pyridin-3-yl]phenyl]oxetane-3-carboxamide
Show/Hide
|
C25H22F4N2O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0579161
|
N-(4-fluorophenyl)-1-[4-[4-(hydroxymethyl)-6-(trifluoromethyl)pyridin-3-yl]phenyl]cyclobutane-1-carboxamide
Show/Hide
|
C24H20F4N2O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0525373
|
3-chloro-N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
|
C21H20ClFN2O2
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0573630
|
N-(4-fluorophenyl)-1-(1-pyridin-2-yl-2,3-dihydroindol-5-yl)cyclobutane-1-carboxamide
Show/Hide
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C24H22FN3O
|
1
|
| 1 |
IC50 = 3.1 nM
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CP0540066
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3-[5-[(3-chlorobenzoyl)amino]pyridin-2-yl]-N-(4-fluorophenyl)oxetane-3-carboxamide
Show/Hide
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C22H17ClFN3O3
|
1
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| 1 |
IC50 = 3.2 nM
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CP0570760
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(2S)-N-(4-fluorophenyl)-2-[3-[(6-fluoroquinazolin-4-yl)amino]-1-bicyclo[1.1.1]pentanyl]propanamide
Show/Hide
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C22H20F2N4O
|
1
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| 1 |
IC50 = 3.2 nM
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CP0446512
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4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(2-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C30H36FN3O4
|
1
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| 1 |
IC50 = 3.3 nM
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CP0575319
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5-[1-[(4-chlorophenyl)carbamoyl]cyclobutyl]-N-ethyl-N-propan-2-yl-2,3-dihydroindole-1-carboxamide
Show/Hide
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C25H30ClN3O2
|
1
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| 1 |
IC50 = 3.3 nM
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CP0547938
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4-chloro-N-[(1R)-1-[(1S,5R)-3-(6-chlorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C23H23Cl2N3O
|
1
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| 1 |
IC50 = 3.4 nM
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CP0521340
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3-chloro-N-[4-[1-[(6-chloropyridin-3-yl)carbamoyl]cyclobutyl]phenyl]benzamide
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C23H19Cl2N3O2
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1
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| 1 |
IC50 = 3.6 nM
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CP0530488
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4-fluoro-N-[(1R)-1-[5-(2-methylpyrimidin-4-yl)-7,8-dihydro-6H-1,5-naphthyridin-2-yl]ethyl]benzamide
Show/Hide
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C22H22FN5O
|
1
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| 1 |
IC50 = 3.6 nM
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CP0565051
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4-chloro-N-((R)-cyclo- propyl((1R,3s,5S,6r)-3- (5,6-difluoro-1H-benzo[d]- imidazol-1-yl)- bicyclo[3.1.0]hexan-6- yl)methyl)benzamide
Show/Hide
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C24H22ClF2N3O
|
1
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| 1 |
IC50 = 3.6 nM
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CP0567325
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N-[1-[(2aR,7bR)-3-(2-methylpyrimidin-4-yl)-1,2,2a,7b-tetrahydrocyclobuta[b]indol-6-yl]cyclopropyl]-4-fluorobenzamide
Show/Hide
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C25H23FN4O
|
1
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| 1 |
IC50 = 3.8 nM
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CP0418475
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4-chloro-N-[(1R)-1-[(1S,5R)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]-3-fluorobenzamide
Show/Hide
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C23H21ClF3N3O
|
1
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| 1 |
IC50 = 3.9 nM
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CP0574932
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1-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-3-(4-methylphenyl)urea
Show/Hide
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C29H35N7O
|
1
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| 1 |
IC50 = 4 nM
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CP0470914
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4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(3-methyl-1,2,4-thiadiazol-5-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C26H34N4O3S
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1
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| 1 |
IC50 = 4 nM
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CP0570781
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4-chloro-N-[1-[(1R,5S)-3-(6,7-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C23H22ClF2N3O
|
1
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| 1 |
IC50 = 4 nM
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CP0568647
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cyclopropyl 5-[1-[(4-chlorobenzoyl)amino]cyclopropyl]-2,3-dihydropyrrolo[3,2-b]pyridine-1-carboxylate
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C21H20ClN3O3
|
1
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| 1 |
IC50 = 4.1 nM
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CP0423812
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4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C31H39N3O4
|
1
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| 1 |
IC50 = 4.2 nM
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CP0479604
|
CHEMBL4873928
Show/Hide
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C23H20ClFN2O2
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1
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| 1 |
IC50 = 4.2 nM
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CP0552814
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(1R,2S)-2-[4-[bis(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]cyclopropane-1-carboxylic acid
Show/Hide
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C26H35N3O3
|
1
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| 1 |
IC50 = 4.2 nM
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CP0176864
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CHEMBL4853672
Show/Hide
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C24H22F2N4O
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1
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| 1 |
IC50 = 4.4 nM
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CP0580142
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cyclopropyl 5-[1-[(4-chlorobenzoyl)amino]cyclobutyl]-2,3-dihydropyrrolo[3,2-b]pyridine-1-carboxylate
Show/Hide
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C22H22ClN3O3
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1
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| 1 |
IC50 = 4.5 nM
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CP0423815
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4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(4-methyl-1,3-thiazol-2-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C27H35N3O3S
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1
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| 1 |
IC50 = 4.6 nM
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CP0555020
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CHEMBL4858219
Show/Hide
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C23H22ClF2N3O
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1
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| 1 |
IC50 = 4.6 nM
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CP0569154
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N-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-2-(4-methylphenyl)acetamide
Show/Hide
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C30H36N6O
|
1
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| 1 |
IC50 = 5 nM
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CP0570736
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N-[1-[(2aS,7bS)-3-(2-methylpyrimidin-4-yl)-1,2,2a,7b-tetrahydrocyclobuta[b]indol-6-yl]cyclopropyl]-4-fluorobenzamide
Show/Hide
|
C25H23FN4O
|
1
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| 1 |
IC50 = 5 nM
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CP0446513
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4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(5-methyl-1,3,4-thiadiazol-2-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C26H34N4O3S
|
1
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| 1 |
IC50 = 5.1 nM
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CP0525781
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3-chloro-2-fluoro-N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
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C21H19ClF2N2O2
|
1
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| 1 |
IC50 = 5.1 nM
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CP0525374
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3-chloro-N-[3-[(2S)-1-[(6-chloropyridin-3-yl)amino]-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
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C20H19Cl2N3O2
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1
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| 1 |
IC50 = 5.2 nM
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CP0562173
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3-chloro-N-[3-[1-[(4-fluorophenyl)carbamoyl]cyclobutyl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
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C23H22ClFN2O2
|
1
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| 1 |
IC50 = 5.2 nM
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CP0557818
|
N-(4-fluorophenyl)-1-[1-(2-methylpyrimidin-4-yl)-2,3-dihydroindol-5-yl]cyclobutane-1-carboxamide
Show/Hide
|
C24H23FN4O
|
1
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| 1 |
IC50 = 5.2 nM
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CP0228785
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4-chloro-N-[1-[(1R,5S)-3-(7-fluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C23H23ClFN3O
|
1
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| 1 |
IC50 = 5.2 nM
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CP0557813
|
4-chloro-N-[(1R)-1-[(1R,5S)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]ethyl]benzamide
Show/Hide
|
C22H20ClF2N3O
|
1
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| 1 |
IC50 = 5.3 nM
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CP0570759
|
(2S)-N-(4-fluorophenyl)-2-[3-(quinazolin-4-ylamino)-1-bicyclo[1.1.1]pentanyl]propanamide
Show/Hide
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C22H21FN4O
|
1
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| 1 |
IC50 = 5.4 nM
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CP0557820
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methyl (2aS,7bS)-6-[1-[(4-fluorobenzoyl)amino]cyclopropyl]-1,2,2a,7b-tetrahydrocyclobuta[b]indole-3-carboxylate
Show/Hide
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C22H21FN2O3
|
1
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| 1 |
IC50 = 5.6 nM
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CP0423816
|
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(4-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C30H36FN3O4
|
1
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| 1 |
IC50 = 5.7 nM
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CP0553537
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4-chloro-N-[1-[(1R,5S)-3-(6-fluoroquinolin-4-yl)oxy-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C25H24ClFN2O2
|
1
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| 1 |
IC50 = 6.1 nM
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CP0388403
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cyclopentyl N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]carbamate
Show/Hide
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C20H25FN2O3
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1
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| 1 |
IC50 = 6.2 nM
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CP0547935
|
CHEMBL4854742
Show/Hide
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C22H23ClFN3O2
|
1
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| 1 |
IC50 = 6.2 nM
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CP0547937
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4-chloro-N-[1-[(1R,5S)-3-(5,7-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C23H22ClF2N3O
|
1
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| 1 |
IC50 = 6.2 nM
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CP0565050
|
N-[1-[(1S,5R)-3-(benzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]-4-chlorobenzamide
Show/Hide
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C23H24ClN3O
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1
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| 1 |
IC50 = 6.3 nM
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CP0577699
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3-[4-(6-cyclopropylpyridin-3-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide
Show/Hide
|
C24H21FN2O2
|
1
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| 1 |
IC50 = 6.3 nM
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CP0550656
|
4-[4-[bis(2-methylpropyl)amino]-3-[(2,4-difluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C28H33F2N3O4
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1
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| 1 |
IC50 = 6.6 nM
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CP0570734
|
2-methoxyethyl 5-[1-[(4-chlorobenzoyl)amino]cyclobutyl]-2,3-dihydropyrrolo[3,2-b]pyridine-1-carboxylate
Show/Hide
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C22H24ClN3O4
|
1
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| 1 |
IC50 = 6.9 nM
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CP0561582
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4-cyano-N-[1-[(1S,5R)-3-(7-fluoroquinazolin-4-yl)oxy-6-bicyclo[3.1.0]hexanyl]ethyl]benzamide
Show/Hide
|
C24H21FN4O2
|
1
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| 1 |
IC50 = 6.9 nM
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CP0219360
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(3E)-3-[(3-bromo-4-fluoroanilino)-(hydroxyamino)methylidene]-4-[2-(sulfamoylamino)ethylimino]-1,2,5-oxadiazolidine
Show/Hide
|
C11H15BrFN7O4S
|
1
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| 1 |
IC50 = 7 nM
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CP0451078
|
CHEMBL4872039
Show/Hide
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C23H22ClF2N3O
|
1
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| 1 |
IC50 = 7 nM
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CP0577174
|
4-chloro-N-[1-[(1R,5S)-3-(4-fluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C23H23ClFN3O
|
1
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| 1 |
IC50 = 7 nM
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CP0539691
|
4-[4-[bis(2-methylpropyl)amino]-3-[(2-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C28H34FN3O4
|
1
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| 1 |
IC50 = 7.1 nM
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CP0423813
|
4-[4-[cyclohexyl(ethyl)amino]-3-[(2-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C28H32FN3O4
|
1
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| 1 |
IC50 = 7.4 nM
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CP0539689
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4-[4-[cyclohexyl(ethyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C29H35N3O4
|
1
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| 1 |
IC50 = 7.5 nM
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CP0446511
|
4-[4-[cyclohexyl(ethyl)amino]-3-[(2,4-difluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C28H31F2N3O4
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1
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| 1 |
IC50 = 7.8 nM
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CP0568646
|
1-[1-(cyclopropanecarbonyl)-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl]-N-(4-fluorophenyl)cyclobutane-1-carboxamide
Show/Hide
|
C22H22FN3O2
|
1
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| 1 |
IC50 = 8 nM
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CP0557819
|
N-[1-[(1aS,6bS)-2-(2-methylpyrimidin-4-yl)-1a,6b-dihydro-1H-cyclopropa[b]indol-5-yl]cyclopropyl]-4-fluorobenzamide
Show/Hide
|
C24H21FN4O
|
1
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| 1 |
IC50 = 8.2 nM
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CP0525635
|
4-fluoro-3-methyl-N-[4-[1-(propylcarbamoyl)cyclobutyl]phenyl]benzamide
Show/Hide
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C22H25FN2O2
|
1
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| 1 |
IC50 = 8.3 nM
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CP0479605
|
4-chloro-N-[2-[(1R,5S)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propan-2-yl]benzamide
Show/Hide
|
C23H22ClF2N3O
|
1
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| 1 |
IC50 = 8.3 nM
|
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CP0547936
|
CHEMBL4848111
Show/Hide
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C24H23ClFN3O2
|
1
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| 1 |
IC50 = 8.4 nM
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CP0570604
|
4-chloro-N-[(1S)-1-[(1R,5S)-3-(6-fluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C23H23ClFN3O
|
1
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| 1 |
IC50 = 8.4 nM
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CP0482521
|
4-[4-[bis(2-methylpropyl)amino]-3-[(4-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C28H34FN3O4
|
1
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| 1 |
IC50 = 8.5 nM
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CP0418474
|
CHEMBL4848514
Show/Hide
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C24H23ClN4O
|
1
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| 1 |
IC50 = 8.8 nM
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CP0530484
|
3-chloro-N-[4-[1-(propylcarbamoyl)cyclobutyl]phenyl]benzamide
Show/Hide
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C21H23ClN2O2
|
2
|
| 1 |
IC50 = 9 nM
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| 2 |
IC50 = 9.2 nM
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CP0574945
|
N-(4-chlorophenyl)-2-(4-phenylcyclohexyl)acetamide
Show/Hide
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C20H22ClNO
|
1
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| 1 |
IC50 = 9.1 nM
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CP0547955
|
4-chloro-N-[(1R)-1-[(1R,5S)-3-(6-fluoro-2-methylbenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C24H25ClFN3O
|
1
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| 1 |
IC50 = 9.2 nM
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CP0536509
|
4-[4-[cyclohexyl(ethyl)amino]-3-[(4-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C28H32FN3O4
|
1
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| 1 |
IC50 = 9.6 nM
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CP0418478
|
4-chloro-N-[1-[(1R,5S)-3-quinolin-4-yloxy-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C25H25ClN2O2
|
1
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| 1 |
IC50 = 9.9 nM
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CP0376942
|
4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C9H7BrFN5O2
|
2
|
| 1 |
IC50 = 10 nM
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| 2 |
IC50 = 12 nM
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CP0383044
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C13H17BrFN6O4P
|
1
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| 1 |
IC50 = 10.1 nM
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CP0488235
|
4-[4-[bis(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C29H37N3O4
|
1
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| 1 |
IC50 = 10.1 nM
|
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CP0443795
|
N'-(3-bromophenyl)-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C13H18BrN6O4P
|
1
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| 1 |
IC50 = 10.5 nM
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CP0580141
|
N-(4-fluorophenyl)-1-(1-pyridin-2-yl-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl)cyclobutane-1-carboxamide
Show/Hide
|
C23H21FN4O
|
1
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| 1 |
IC50 = 10.9 nM
|
|
|
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CP0558928
|
US10034939, Example 5
Show/Hide
|
C11H13ClFN7O4S
|
1
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| 1 |
IC50 = 11 nM
|
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CP0578505
|
cyclopropyl 5-[1-[(4-fluorobenzoyl)amino]cyclopropyl]spiro[2H-pyrrolo[3,2-b]pyridine-3,1'-cyclopropane]-1-carboxylate
Show/Hide
|
C23H22FN3O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
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CP0557682
|
CHEMBL4862584
Show/Hide
|
C23H22Cl3N3O
|
1
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| 1 |
IC50 = 12 nM
|
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CP0573631
|
N-(4-chlorophenyl)-1-[1-(2-methylpyrimidin-4-yl)-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl]cyclobutane-1-carboxamide
Show/Hide
|
C23H22ClN5O
|
1
|
| 1 |
IC50 = 12.5 nM
|
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CP0475300
|
2-[4-[bis(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C29H35N3O3
|
2
|
| 1 |
IC50 = 13 nM
|
|
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| 2 |
IC50 = 16.4 nM
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CP0575523
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-(methylamino)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C10H9BrFN5O2
|
1
|
| 1 |
IC50 = 14 nM
|
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CP0541610
|
2-[4-[cyclohexyl(methyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C28H31N3O3
|
1
|
| 1 |
IC50 = 14 nM
|
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CP0570779
|
4-chloro-N-[[(1S,5R)-3-(6-fluoroquinolin-4-yl)oxy-6-bicyclo[3.1.0]hexanyl]methyl]benzamide
Show/Hide
|
C23H20ClFN2O2
|
1
|
| 1 |
IC50 = 14 nM
|
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CP0561231
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N'-(3-chlorophenyl)-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
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C13H18ClN6O4P
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1
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| 1 |
IC50 = 14.4 nM
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CP0566598
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N'-(3-bromophenyl)-4-[2-[[ethoxy(ethyl)phosphoryl]amino]ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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C15H22BrN6O4P
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1
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| 1 |
IC50 = 14.6 nM
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CP0413066
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US10034939, Example 2
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C12H14BrFN6O4S
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1
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| 1 |
IC50 = 16 nM
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CP0572866
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N'-[(7S)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxy-4-[2-(sulfamoylamino)ethylsulfanyl]-1,2,5-oxadiazole-3-carboximidamide
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C13H15FN6O4S2
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1
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| 1 |
IC50 = 16 nM
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CP0499152
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4-Amino-N-(3-bromophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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C9H8BrN5O2
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1
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| 1 |
IC50 = 17 nM
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CP0540418
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N-[2-[[4-[N'-(3-bromo-4-fluorophenyl)-N-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl]amino]ethyl]acetamide
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C13H14BrFN6O3
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1
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| 1 |
IC50 = 17 nM
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CP0412230
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2-[[4-[N'-[(7S)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl]sulfanyl]-N-(2-hydroxyethyl)acetamide
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C15H16FN5O4S
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1
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| 1 |
IC50 = 17 nM
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CP0388666
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3-chloro-N-[2-[1-[(4-fluorophenyl)carbamoyl]cyclobutyl]pyrimidin-5-yl]benzamide
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C22H18ClFN4O2
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1
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| 1 |
IC50 = 17 nM
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CP0472242
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N'-[4-fluoro-3-(trifluoromethyl)phenyl]-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C14H17F4N6O4P
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1
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| 1 |
IC50 = 17.1 nM
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CP0563027
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N'-(3-chloro-4-fluorophenyl)-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C13H17ClFN6O4P
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1
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| 1 |
IC50 = 17.9 nM
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CP0566156
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3-chloro-N-[3-[1-(4-fluoroanilino)-2-methyl-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
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C22H22ClFN2O2
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1
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| 1 |
IC50 = 18 nM
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CP0561606
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4-chloro-N-[1-[(1R,5S)-3-(1,5-naphthyridin-4-yloxy)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
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C24H24ClN3O2
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1
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| 1 |
IC50 = 18 nM
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CP0560096
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N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[4-[[methoxy(methyl)phosphoryl]amino]butylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C15H21BrFN6O4P
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1
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| 1 |
IC50 = 18.9 nM
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CP0222132
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4-Amino-N-(3-chlorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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C9H8ClN5O2
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1
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| 1 |
IC50 = 19 nM
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CP0236732
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4-amino-N-(3-chloro-4-fluorophenyl)-N′-hydroxy-1,2,5-oxadiazole-3-carboximidamide
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C9H7ClFN5O2
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1
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| 1 |
IC50 = 19 nM
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CP0468941
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3-chloro-N-[4-[1-(oxan-4-ylcarbamoyl)cyclobutyl]phenyl]benzamide
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C23H25ClN2O3
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1
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| 1 |
IC50 = 19 nM
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CP0517048
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CHEMBL4862755
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C21H18ClF2N3O
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1
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| 1 |
IC50 = 19 nM
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CP0555019
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4-chloro-N-[1-[(1R,5S)-3-(4-cyclopropyltriazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
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C21H25ClN4O
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1
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| 1 |
IC50 = 19 nM
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CP0561608
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4-chloro-N-[1-[(1S,5R)-3-(6-fluoroimidazo[4,5-b]pyridin-3-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C22H22ClFN4O
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1
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| 1 |
IC50 = 19 nM
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CP0421110
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N'-(3-bromo-4-fluorophenyl)-4-[2-[[ethoxy(methyl)phosphoryl]amino]ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C14H19BrFN6O4P
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1
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| 1 |
IC50 = 19.1 nM
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CP0482467
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4-[4-[cyclohexyl(methyl)amino]-3-[(2,4-difluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
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C27H29F2N3O4
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1
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| 1 |
IC50 = 19.5 nM
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CP0159403
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8-fluoro-2-[(4-methylpiperazin-1-yl)methyl]indolo[2,1-b]quinazoline-6,12-dione
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C21H19FN4O2
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1
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| 1 |
IC50 = 20 nM
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CP0447827
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8-fluoro-2-(morpholin-4-ylmethyl)indolo[2,1-b]quinazoline-6,12-dione
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C20H16FN3O3
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1
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| 1 |
IC50 = 20 nM
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CP0492024
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2-[(dimethylamino)methyl]-8-fluoroindolo[2,1-b]quinazoline-6,12-dione
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C18H14FN3O2
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1
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| 1 |
IC50 = 20 nM
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CP0531156
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4-amino-N'-[(7S)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C11H10FN5O2
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1
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| 1 |
IC50 = 20 nM
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CP0329967
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ethyl (E)-3-(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)prop-2-enoate
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C20H13FN2O4
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1
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| 1 |
IC50 = 20 nM
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CP0525784
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propan-2-yl N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]carbamate
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C18H23FN2O3
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1
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| 1 |
IC50 = 20 nM
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CP0480279
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4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(3-cyclopropyl-1,2,4-thiadiazol-5-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
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C28H36N4O3S
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1
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| 1 |
IC50 = 20.3 nM
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CP0462433
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N'-(3-bromo-4-fluorophenyl)-4-[2-[[ethoxy(ethyl)phosphoryl]amino]ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C15H21BrFN6O4P
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1
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| 1 |
IC50 = 20.8 nM
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CP0443796
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N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-N'-[3-(trifluoromethyl)phenyl]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C14H18F3N6O4P
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1
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| 1 |
IC50 = 21 nM
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CP0576102
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N-(4-fluorophenyl)-1-[1-(2-methylpyrimidin-4-yl)-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl]cyclobutane-1-carboxamide
Show/Hide
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C23H22FN5O
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1
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| 1 |
IC50 = 21 nM
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CP0558927
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N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-(2-hydroxyethylamino)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C11H11BrFN5O3
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1
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| 1 |
IC50 = 22 nM
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CP0219216
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5-[3-[(2-chlorophenyl)carbamoylamino]-4-(5,6,7,8-tetrahydronaphthalen-1-yloxy)phenyl]-2-methoxybenzoic acid
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C31H27ClN2O5
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1
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| 1 |
IC50 = 22 nM
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CP0555721
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4-chloro-N-[1-[(1R,5S)-3-imidazo[4,5-c]pyridin-1-yl-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C22H23ClN4O
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1
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| 1 |
IC50 = 22 nM
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CP0451080
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2-[4-[cyclopentyl(ethyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C28H31N3O3
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1
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| 1 |
IC50 = 23 nM
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CP0383046
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N'-(4-fluoro-3-methylphenyl)-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C14H20FN6O4P
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1
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| 1 |
IC50 = 23 nM
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CP0574942
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4-chloro-N-[1-[(1R,5S)-3-(1,6-naphthyridin-4-yloxy)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
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C24H24ClN3O2
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1
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| 1 |
IC50 = 23 nM
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CP0462434
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N'-(3-bromophenyl)-N-hydroxy-4-[3-[[methoxy(methyl)phosphoryl]amino]propylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C14H20BrN6O4P
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1
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| 1 |
IC50 = 24 nM
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CP0491766
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N'-(3-cyano-4-fluorophenyl)-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C14H17FN7O4P
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1
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| 1 |
IC50 = 24 nM
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CP0412229
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N-[2-[[4-[N'-[(7S)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl]sulfanyl]ethyl]acetamide
Show/Hide
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C15H16FN5O3S
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1
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| 1 |
IC50 = 24 nM
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CP0530064
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N'-[(7S)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C13H16FN7O4S
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1
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| 1 |
IC50 = 24 nM
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CP0564623
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N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[2-[[methyl(propan-2-yloxy)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C15H21BrFN6O4P
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1
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| 1 |
IC50 = 25 nM
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CP0563025
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N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[5-[[methoxy(methyl)phosphoryl]amino]pentylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C16H23BrFN6O4P
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1
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| 1 |
IC50 = 26 nM
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CP0531157
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N-[2-[[4-[N'-[(7S)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl]amino]ethyl]acetamide
Show/Hide
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C15H17FN6O3
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1
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| 1 |
IC50 = 26 nM
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CP0561605
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(5S)-6,6-dimethyl-8-[7-(trifluoromethyl)imidazo[1,5-a]pyridin-5-yl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C17H18F3N5O2
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1
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| 1 |
IC50 = 26 nM
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CP0525782
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6-chloro-N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]pyridine-2-carboxamide
Show/Hide
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C20H19ClFN3O2
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1
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| 1 |
IC50 = 27 nM
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CP0482137
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1-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-3-(4-methylphenyl)imidazolidin-2-one
Show/Hide
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C31H37N7O
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1
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| 1 |
IC50 = 28 nM
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CP0563099
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N-(4-chlorophenyl)-6-quinolin-4-yloxyspiro[2.5]octane-2-carboxamide
Show/Hide
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C24H23ClN2O2
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1
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| 1 |
IC50 = 28 nM
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CP0475301
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4-[4-[cyclohexyl(methyl)amino]-3-[(2-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C27H30FN3O4
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1
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| 1 |
IC50 = 29.5 nM
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CP0570675
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4-chloro-N-[1-[(1R,5S)-3-imidazo[4,5-c]pyridin-3-yl-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C22H23ClN4O
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1
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| 1 |
IC50 = 30 nM
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CP0525636
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3-chloro-N-[4-[1-[(4-fluorophenyl)carbamoyl]-3-hydroxycyclobutyl]phenyl]benzamide
Show/Hide
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C24H20ClFN2O3
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1
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| 1 |
IC50 = 32 nM
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CP0574941
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N-(4-chlorophenyl)-4-(2-quinolin-4-ylethyl)piperidine-1-carboxamide
Show/Hide
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C23H24ClN3O
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1
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| 1 |
IC50 = 32 nM
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CP0343389
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4-cyano-N-[(1R)-1-[(1S,5R)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]ethyl]benzamide
Show/Hide
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C23H20F2N4O
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1
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| 1 |
IC50 = 33 nM
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CP0570782
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4-chloro-N-[1-[(1R,5S)-3-imidazo[4,5-b]pyridin-3-yl-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C22H23ClN4O
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1
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| 1 |
IC50 = 33 nM
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CP0533522
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4-fluoro-N-[1-[1-(2-methylpyrimidin-4-yl)spiro[2H-pyrrolo[3,2-b]pyridine-3,1'-cyclopropane]-5-yl]cyclopropyl]benzamide
Show/Hide
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C24H22FN5O
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1
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| 1 |
IC50 = 34 nM
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CP0536121
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N'-(3-bromo-4-fluorophenyl)-4-(ethylamino)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C11H11BrFN5O2
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1
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| 1 |
IC50 = 35 nM
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CP0575408
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N'-(3-chloro-4-fluorophenyl)-N-hydroxy-4-[3-[[methoxy(methyl)phosphoryl]amino]propylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C14H19ClFN6O4P
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1
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| 1 |
IC50 = 35 nM
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CP0557812
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4-cyano-N-[(1R)-1-[(1R,5S)-3-(6-cyanobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C25H23N5O
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1
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| 1 |
IC50 = 35 nM
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CP0488238
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4-[4-[cyclohexyl(methyl)amino]-3-[(4-fluorophenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C27H30FN3O4
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1
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| 1 |
IC50 = 35.7 nM
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CP0566600
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N'-(3-cyanophenyl)-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C14H18N7O4P
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1
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| 1 |
IC50 = 36 nM
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CP0536510
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4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(2-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C31H39N3O4
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1
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| 1 |
IC50 = 37.1 nM
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CP0472240
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N'-(3-bromo-4-fluorophenyl)-4-[2-[[ethoxy(propyl)phosphoryl]amino]ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C16H23BrFN6O4P
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1
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| 1 |
IC50 = 37.2 nM
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CP0480281
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4-[4-[cyclohexyl(methyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C28H33N3O4
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1
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| 1 |
IC50 = 38.1 nM
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CP0543473
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2-[3-[(4-methylphenyl)carbamoylamino]-4-[2-methylpropyl(propan-2-yl)amino]phenyl]benzoic acid
Show/Hide
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C28H33N3O3
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1
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| 1 |
IC50 = 42 nM
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CP0474010
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N'-(3-bromo-4-fluorophenyl)-4-[3-[[ethoxy(ethyl)phosphoryl]amino]propylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C16H23BrFN6O4P
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1
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| 1 |
IC50 = 44 nM
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CP0540477
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2-[4-(dibutylamino)-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C29H35N3O3
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1
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| 1 |
IC50 = 45 nM
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CP0575323
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4-chloro-N-[1-[1-(2-methylpyrimidin-4-yl)-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl]cyclobutyl]benzamide
Show/Hide
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C23H22ClN5O
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1
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| 1 |
IC50 = 46 nM
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CP0106740
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2-methoxy-5-[3-[(2-methylphenyl)carbamoylamino]-4-(5,6,7,8-tetrahydronaphthalen-1-yloxy)phenyl]benzoic acid
Show/Hide
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C32H30N2O5
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1
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| 1 |
IC50 = 49 nM
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CP0061249
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2-[[4-[N'-[(7S)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl]amino]-N-(2-hydroxyethyl)acetamide
Show/Hide
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C15H17FN6O4
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1
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| 1 |
IC50 = 49 nM
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CP0535719
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2-methoxy-5-[3-[(4-methylphenyl)carbamoylamino]-4-(2-methyl-3-prop-2-ynoxyphenoxy)phenyl]benzoic acid
Show/Hide
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C32H28N2O6
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1
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| 1 |
IC50 = 50 nM
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CP0539285
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5-[3-[(2-fluorophenyl)carbamoylamino]-4-(5,6,7,8-tetrahydronaphthalen-1-yloxy)phenyl]-2-methoxybenzoic acid
Show/Hide
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C31H27FN2O5
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1
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| 1 |
IC50 = 50 nM
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CP0562042
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4-amino-N'-[(7S)-7-bicyclo[4.2.0]octa-1,3,5-trienyl]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C11H11N5O2
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1
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| 1 |
IC50 = 52 nM
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CP0444610
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CHEMBL4870418
Show/Hide
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C24H23ClN4O
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1
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| 1 |
IC50 = 52 nM
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CP0480280
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4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(3-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C31H39N3O4
|
1
|
| 1 |
IC50 = 52.7 nM
|
|
|
|
CP0444080
|
2-[[4-[N'-[(7S)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxycarbamimidoyl]-1,2,5-oxadiazol-3-yl]amino]acetamide
Show/Hide
|
C13H13FN6O3
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0499153
|
4-Amino-N-(3-ethylphenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C11H13N5O2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0482520
|
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(5-methyl-1,3,4-oxadiazol-2-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C26H34N4O4
|
1
|
| 1 |
IC50 = 55.8 nM
|
|
|
|
CP0577983
|
6-fluoro-5-[1-[2-fluoro-4-(1-methylpyrazol-4-yl)phenyl]piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C25H23F2N5
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0525783
|
cyclopropyl N-[3-[(2S)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]carbamate
Show/Hide
|
C18H21FN2O3
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0323382
|
(E)-3-(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)prop-2-enoic acid
Show/Hide
|
C18H9FN2O4
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0517055
|
(5R)-6,6-dimethyl-8-[7-(trifluoromethyl)imidazo[1,5-a]pyridin-5-yl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C17H18F3N5O2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0566944
|
2-methoxy-5-[3-(phenylcarbamoylamino)-4-(5,6,7,8-tetrahydronaphthalen-1-yloxy)phenyl]benzoic acid
Show/Hide
|
C31H28N2O5
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0570674
|
4-chloro-N-[1-[(1R,5S)-3-imidazo[4,5-b]pyridin-1-yl-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C22H23ClN4O
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0539639
|
6-fluoro-5-[1-[3-fluoro-4-(1-methylpyrazol-4-yl)phenyl]piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C25H23F2N5
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0570780
|
4-chloro-N-[1-[(1R,5S)-3-(3-cyclopropyl-1,2,4-triazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C21H25ClN4O
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0550403
|
4′-(2-tert-Butylphenoxy)-3′-(3-p-tolylureido)biphenyl-2-carboxylic acid
Show/Hide
|
C31H30N2O4
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0420665
|
8-fluoro-2-(piperazin-1-ylmethyl)indolo[2,1-b]quinazoline-6,12-dione
Show/Hide
|
C20H17FN4O2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0561584
|
CHEMBL4870583
Show/Hide
|
C24H23ClN4O
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0577535
|
4-amino-N'-(3,4-difluoro-7-bicyclo[4.2.0]octa-1,3,5-trienyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C11H9F2N5O2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0482138
|
1-[2-[bis(2-methylpropyl)amino]-5-[2-(trifluoromethylsulfonylamino)phenyl]phenyl]-3-(4-methylphenyl)urea
Show/Hide
|
C29H35F3N4O3S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0534229
|
(5S)-6-fluoro-5-[1-[4-(1-methylpyrazol-4-yl)phenyl]piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C25H24FN5
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0367249
|
8-fluoro-2-(triazol-1-ylmethyl)indolo[2,1-b]quinazoline-6,12-dione
Show/Hide
|
C18H10FN5O2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0577751
|
3-[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide
Show/Hide
|
C21H18FN3O3
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0557817
|
4-chloro-N-[[1-(3-chlorobenzoyl)-2,3-dihydroindol-5-yl]methyl]benzamide
Show/Hide
|
C23H18Cl2N2O2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0554663
|
N-[[1-(2-methylpropanoyl)-2,3-dihydroindol-5-yl]methyl]furan-2-carboxamide
Show/Hide
|
C18H20N2O3
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0553372
|
4-chloro-N-[1-[1-[2-(trifluoromethyl)pyrimidin-4-yl]-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl]cyclobutyl]benzamide
Show/Hide
|
C23H19ClF3N5O
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0566601
|
N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-N'-(3-methylphenyl)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C14H21N6O4P
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0545971
|
1-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-1-methyl-3-(4-methylphenyl)urea
Show/Hide
|
C30H37N7O
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0565127
|
4-(2-aminoethylamino)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C11H12BrFN6O2
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0417939
|
N-(4-chloro-3-ethylphenyl)-2H-triazol-4-amine
Show/Hide
|
C10H11ClN4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0542162
|
N-(4-chloro-2-ethylphenyl)-2H-triazol-4-amine
Show/Hide
|
C10H11ClN4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0566671
|
N-(4-fluoro-2-methylphenyl)-2H-triazol-4-amine
Show/Hide
|
C9H9FN4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0571438
|
2-chloro-5-(2H-triazol-4-ylamino)benzonitrile
Show/Hide
|
C9H6ClN5
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0575464
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-(2-methoxyethylamino)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C12H13BrFN5O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0219217
|
2-methoxy-5-[3-[(3-methylphenyl)carbamoylamino]-4-(5,6,7,8-tetrahydronaphthalen-1-yloxy)phenyl]benzoic acid
Show/Hide
|
C32H30N2O5
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0575905
|
2-methoxy-5-[3-[(4-methylphenyl)carbamoylamino]-4-(5,6,7,8-tetrahydronaphthalen-1-yloxy)phenyl]benzoic acid
Show/Hide
|
C32H30N2O5
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0577982
|
6-fluoro-5-[1-[4-(1-methylpyrazol-4-yl)phenyl]piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C25H24FN5
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0563026
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[1-[methoxy(methyl)phosphoryl]pyrrolidin-3-yl]amino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C15H19BrFN6O4P
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0422692
|
N-(4-chlorophenyl)-2-(4-quinolin-4-yloxycyclohexyl)acetamide
Show/Hide
|
C23H23ClN2O2
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0443794
|
4-[2-[[benzyl(ethoxy)phosphoryl]amino]ethylamino]-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C20H23BrFN6O4P
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0376941
|
4-Amino-N'-hydroxy-N-(3-methylphenyl)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C10H11N5O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0558612
|
5-[4-(2-tert-butylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-ethoxybenzoic acid
Show/Hide
|
C33H34N2O5
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0558303
|
6-fluoro-5-[1-[3-methyl-4-(1-methylpyrazol-4-yl)phenyl]piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C26H26FN5
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0421109
|
N'-(3-bromo-4-fluorophenyl)-4-[2-[[ethoxy(naphthalen-1-ylmethyl)phosphoryl]amino]ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C24H25BrFN6O4P
|
1
|
| 1 |
IC50 = 126 nM
|
|
|
|
CP0580039
|
N-(4-fluorophenyl)-1-[1-[2-(trifluoromethyl)pyrimidin-4-yl]-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl]cyclobutane-1-carboxamide
Show/Hide
|
C23H19F4N5O
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
|
CP0420666
|
tert-butyl 4-[(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)methyl]piperazine-1-carboxylate
Show/Hide
|
C25H25FN4O4
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0383045
|
N'-(3-bromo-4-fluorophenyl)-4-[2-[[ethoxy(phenyl)phosphoryl]amino]ethylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C19H21BrFN6O4P
|
1
|
| 1 |
IC50 = 132 nM
|
|
|
|
CP0566597
|
N'-(3-bromo-4-fluorophenyl)-4-[3-[[ethoxy(propyl)phosphoryl]amino]propylamino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C17H25BrFN6O4P
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0570778
|
N-(4-chlorophenyl)-2-[3-(quinolin-4-yloxymethyl)azetidin-1-yl]propanamide
Show/Hide
|
C22H22ClN3O2
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0564622
|
N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[[1-[methoxy(methyl)phosphoryl]piperidin-3-yl]amino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C16H21BrFN6O4P
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0531155
|
4-amino-N'-(3-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C11H10FN5O2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0388564
|
methyl 1-[(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)methyl]piperidine-4-carboxylate
Show/Hide
|
C23H20FN3O4
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0480283
|
4-[4-[cyclohexyl(ethyl)amino]-3-[(2-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C29H35N3O4
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0482140
|
2-[4-[(4aS,8aS)-3,4,4a,5,6,7,8,8a-octahydro-2H-quinolin-1-yl]-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C30H33N3O3
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
|
CP0575904
|
5-[4-(2,3-dimethylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-methoxybenzoic acid
Show/Hide
|
C30H28N2O5
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0359321
|
8-fluoro-6,12-dioxoindolo[2,1-b]quinazoline-2-carbaldehyde
Show/Hide
|
C16H7FN2O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0577750
|
1-[4-(6-cyclopropylpyridin-3-yl)phenyl]-N-propylcyclobutane-1-carboxamide
Show/Hide
|
C22H26N2O
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0535768
|
6-fluoro-5-[1-(3-fluorophenyl)piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C21H19F2N3
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0431572
|
2-[(4-methylpiperazin-1-yl)methyl]indolo[2,1-b]quinazoline-6,12-dione
Show/Hide
|
C21H20N4O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0577036
|
6-fluoro-5-[1-(1-methylindol-6-yl)piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C24H23FN4
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0670151
|
3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
|
C12H9FN2O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0579633
|
3-[4-(4-cyclopropyl-6-oxopyrimidin-1-yl)phenyl]-N-(4-fluorophenyl)oxetane-3-carboxamide
Show/Hide
|
C23H20FN3O3
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0423814
|
4-[4-[cyclohexyl(ethyl)amino]-3-[(3-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C29H35N3O4
|
1
|
| 1 |
IC50 = 223 nM
|
|
|
|
CP0085227
|
4-Amino-N'-hydroxy-N-(3-isopropylphenyl)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C12H15N5O2
|
1
|
| 1 |
IC50 = 225 nM
|
|
|
|
CP0368208
|
(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)boronic acid
Show/Hide
|
C15H8BFN2O4
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0541053
|
3-chloro-N-[3-[(2R)-1-(4-fluoroanilino)-1-oxopropan-2-yl]-1-bicyclo[1.1.1]pentanyl]benzamide
Show/Hide
|
C21H20ClFN2O2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0539638
|
6-fluoro-5-[1-(4-pyridin-3-ylphenyl)piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C26H23FN4
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0444078
|
4-amino-N'-[(1S)-2,3-dihydro-1H-inden-1-yl]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C12H13N5O2
|
1
|
| 1 |
IC50 = 243 nM
|
|
|
|
CP0482128
|
3-[4-(2-tert-butylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-5-chlorobenzoic acid
Show/Hide
|
C31H29ClN2O4
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0469460
|
6-fluoro-5-[1-[3-(1-methylpyrazol-4-yl)phenyl]piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C25H24FN5
|
1
|
| 1 |
IC50 = 253 nM
|
|
|
|
CP0539716
|
4-[4-[cyclohexyl(methyl)amino]-3-[(2-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C28H33N3O4
|
1
|
| 1 |
IC50 = 258 nM
|
|
|
|
CP0376940
|
4-Amino-N-(3-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C9H8FN5O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0571819
|
(6,6-dimethyl-7,10,11-trioxonaphtho[1,2-g][1]benzofuran-1-yl)methyl acetate
Show/Hide
|
C21H16O6
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0558926
|
4-(benzylamino)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C16H13BrFN5O2
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0566943
|
5-[4-(2,3-dihydro-1H-inden-4-yloxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-methoxybenzoic acid
Show/Hide
|
C31H28N2O5
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0547730
|
6-fluoro-5-[1-(4-pyridin-4-ylphenyl)piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C26H23FN4
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0576362
|
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(3-phenyl-1,2,4-thiadiazol-5-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C31H36N4O3S
|
1
|
| 1 |
IC50 = 306 nM
|
|
|
|
CP0444805
|
6-fluoro-5-[1-[5-(1-methylpyrazol-4-yl)pyrimidin-2-yl]piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C23H22FN7
|
1
|
| 1 |
IC50 = 324 nM
|
|
|
|
CP0476678
|
2-methoxy-5-[3-[(4-methylphenyl)carbamoylamino]-4-(2-propylphenoxy)phenyl]benzoic acid
Show/Hide
|
C31H30N2O5
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0451076
|
4-chloro-N-[[(1S,5R)-3-(6-fluoroquinolin-4-yl)oxy-6-bicyclo[3.1.0]hexanyl]methyl]benzamide
Show/Hide
|
C23H20ClFN2O2
|
1
|
| 1 |
IC50 = 334 nM
|
|
|
|
CP0540430
|
2-methoxy-5-[3-[(4-methylphenyl)carbamoylamino]-4-(2-propan-2-ylphenoxy)phenyl]benzoic acid
Show/Hide
|
C31H30N2O5
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0488239
|
4-[4-[cyclohexyl(2-methylpropyl)amino]-3-[(4-phenyl-1,3-thiazol-2-yl)amino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
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C32H37N3O3S
|
1
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| 1 |
IC50 = 341 nM
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CP0574944
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4-chloro-N-[1-[(1R,5S)-3-(6-cyanoimidazo[4,5-b]pyridin-3-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C23H22ClN5O
|
1
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| 1 |
IC50 = 343 nM
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CP0541616
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2-[4-[bis(cyclopropylmethyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C29H31N3O3
|
1
|
| 1 |
IC50 = 348 nM
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CP0428965
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5-[4-(2-tert-butylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-methoxybenzoic acid
Show/Hide
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C32H32N2O5
|
1
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| 1 |
IC50 = 350 nM
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CP0574534
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4-[4-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)piperidin-1-yl]benzonitrile
Show/Hide
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C22H19FN4
|
1
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| 1 |
IC50 = 353 nM
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CP0243946
|
O-[(3,5-difluorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
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C13H12ClF2NO
|
1
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| 1 |
IC50 = 357 nM
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CP0555722
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4-chloro-N-[1-[(1R,5S)-3-(6-cyanoimidazo[4,5-b]pyridin-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C23H22ClN5O
|
1
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| 1 |
IC50 = 357 nM
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CP0329965
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methyl 1-[(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)methyl]piperidine-3-carboxylate
Show/Hide
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C23H20FN3O4
|
1
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| 1 |
IC50 = 370 nM
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CP0148155
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N-[2-(dimethylamino)ethyl]-9-methylsulfanyl-5,12-dioxoindolizino[3,2-g]quinoline-11-carboxamide
Show/Hide
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C21H20N4O3S
|
1
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| 1 |
IC50 = 372 nM
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CP0559790
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3-[2-[bis(2-methylpropyl)amino]-5-[2-(2H-tetrazol-5-yl)phenyl]phenyl]-1-methyl-1-(4-methylphenyl)urea
Show/Hide
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C30H37N7O
|
1
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| 1 |
IC50 = 405 nM
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CP0562247
|
CHEMBL4855340
Show/Hide
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C24H24ClFN2O
|
1
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| 1 |
IC50 = 420 nM
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CP0355381
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N-((R)-1-((1R,3S,5S,6r)-3- (5,6-difluoro-1H-benzo[d]- imidazol-1-yl)bicyclo- [3.1.0]hexan-6-yl)propyl)- 3-fluorobicyclo[1.1.1]- pentane-1-carboxamide
Show/Hide
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C22H24F3N3O
|
1
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| 1 |
IC50 = 426 nM
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CP0119011
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(1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1- a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol
Show/Hide
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C18H21FN2O2
|
1
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| 1 |
IC50 = 434 nM
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CP0537980
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2-[4-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)piperidin-1-yl]-1,3-benzothiazole
Show/Hide
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C22H19FN4S
|
1
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| 1 |
IC50 = 440 nM
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CP0552813
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1-[2-[bis(2-methylpropyl)amino]-5-[N-hydroxy-N'-(4-methylphenyl)carbamimidoyl]phenyl]-3-pyrimidin-5-ylurea
Show/Hide
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C27H35N7O2
|
1
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| 1 |
IC50 = 440 nM
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CP0577463
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1-[2-[bis(2-methylpropyl)amino]-5-[N'-(3-bromo-4-fluorophenyl)-N-hydroxycarbamimidoyl]phenyl]-3-(4-chlorophenyl)urea
Show/Hide
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C28H32BrClFN5O2
|
1
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| 1 |
IC50 = 440 nM
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CP0578578
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1-(hydroxymethyl)-6,6-dimethyl-8,9-dihydronaphtho[1,2-g][1]benzofuran-7,10,11-trione
Show/Hide
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C19H16O5
|
1
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| 1 |
IC50 = 450 nM
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CP0301242
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4-Amino-N'-hydroxy-N-phenyl-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C9H9N5O2
|
1
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| 1 |
IC50 = 490 nM
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CP0569157
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2-[4-(cyclohexylamino)-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C27H29N3O3
|
1
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| 1 |
IC50 = 504 nM
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CP0539690
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4-[4-[cyclohexyl(methyl)amino]-3-[(3-methylphenyl)carbamoylamino]phenyl]-2,5-dimethylfuran-3-carboxylic acid
Show/Hide
|
C28H33N3O4
|
1
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| 1 |
IC50 = 539 nM
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CP0476679
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5-[4-(2-ethylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-methoxybenzoic acid
Show/Hide
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C30H28N2O5
|
1
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| 1 |
IC50 = 540 nM
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CP0561940
|
6-fluoro-5-(1-phenylpiperidin-4-yl)-5H-imidazo[5,1-a]isoindole
Show/Hide
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C21H20FN3
|
1
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| 1 |
IC50 = 544 nM
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CP0547728
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5-cyclohexyl-6-fluoro-5H-imidazo[5,1-a]isoindole
Show/Hide
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C16H17FN2
|
1
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| 1 |
IC50 = 568 nM
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CP0540429
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3-[4-(2-tert-butylphenoxy)-3-[(3-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C31H30N2O4
|
1
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| 1 |
IC50 = 570 nM
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CP0535767
|
2-[4-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)piperidin-1-yl]-1,3-thiazole
Show/Hide
|
C18H17FN4S
|
1
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| 1 |
IC50 = 571 nM
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CP0188708
|
O-[(3-bromophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
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C13H13BrClNO
|
1
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| 1 |
IC50 = 590 nM
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CP0438462
|
2-(dimethylamino)-8-fluoroindolo[2,1-b]quinazoline-6,12-dione
Show/Hide
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C17H12FN3O2
|
1
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| 1 |
IC50 = 590 nM
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CP0557546
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2-[4-(2-tert-butylanilino)-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C31H31N3O3
|
1
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| 1 |
IC50 = 600 nM
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CP0569395
|
1-(fluoromethyl)-6,6-dimethylnaphtho[1,2-g][1]benzofuran-7,10,11-trione
Show/Hide
|
C19H13FO4
|
1
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| 1 |
IC50 = 650 nM
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CP0541334
|
2-[4-[bis(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]-N-methylsulfonylbenzamide
Show/Hide
|
C30H38N4O4S
|
1
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| 1 |
IC50 = 661 nM
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CP0569762
|
1-(chloromethyl)-6,6-dimethylnaphtho[1,2-g][1]benzofuran-7,10,11-trione
Show/Hide
|
C19H13ClO4
|
1
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| 1 |
IC50 = 680 nM
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CP0539284
|
5-[4-(3-tert-butylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-methoxybenzoic acid
Show/Hide
|
C32H32N2O5
|
1
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| 1 |
IC50 = 690 nM
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CP0535769
|
6-fluoro-5-[1-[2-methyl-4-(1-methylpyrazol-4-yl)phenyl]piperidin-4-yl]-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C26H26FN5
|
1
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| 1 |
IC50 = 691 nM
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CP0329966
|
methyl 1-[(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)methyl]pyrrolidine-2-carboxylate
Show/Hide
|
C22H18FN3O4
|
1
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| 1 |
IC50 = 700 nM
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CP0116110
|
N-[2-(dimethylamino)ethyl]-5,12-dioxoindolizino[2,3-g]quinoline-6-carboxamide
Show/Hide
|
C20H18N4O3
|
1
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| 1 |
IC50 = 738 nM
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CP0111908
|
8-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolo[2,1-b]quinazoline-6,12-dione
Show/Hide
|
C21H18BFN2O4
|
1
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| 1 |
IC50 = 750 nM
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CP0489554
|
8-fluoro-2-piperazin-1-ylindolo[2,1-b]quinazoline-6,12-dione
Show/Hide
|
C19H15FN4O2
|
1
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| 1 |
IC50 = 760 nM
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CP0580020
|
1-[2-[bis(2-methylpropyl)amino]-5-[N'-(3-bromo-4-fluorophenyl)-N-hydroxycarbamimidoyl]phenyl]-3-(4-methylphenyl)urea
Show/Hide
|
C29H35BrFN5O2
|
1
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| 1 |
IC50 = 760 nM
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CP0539283
|
3-[4-(2-tert-butylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C31H30N2O4
|
2
|
| 1 |
IC50 = 790 nM
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| 2 |
IC50 > 1000 nM
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CP0571820
|
(6,6-dimethyl-7,10,11-trioxo-8,9-dihydronaphtho[1,2-g][1]benzofuran-1-yl)methyl acetate
Show/Hide
|
C21H18O6
|
1
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| 1 |
IC50 = 810 nM
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CP0564734
|
5-[4-(2-chlorophenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-methoxybenzoic acid
Show/Hide
|
C28H23ClN2O5
|
1
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| 1 |
IC50 = 830 nM
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CP0535718
|
2-methoxy-5-[4-(2-methylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C29H26N2O5
|
1
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| 1 |
IC50 = 840 nM
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CP0427653
|
2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-[2-(3-methoxyphenyl)ethyl]acetamide
Show/Hide
|
C21H21N3O2
|
1
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| 1 |
IC50 = 840 nM
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CP0566599
|
N'-(4-fluorophenyl)-N-hydroxy-4-[2-[[methoxy(methyl)phosphoryl]amino]ethylamino]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C13H18FN6O4P
|
1
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| 1 |
IC50 = 850 nM
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CP0444079
|
4-amino-N'-[(7R)-4-fluoro-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C11H10FN5O2
|
1
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| 1 |
IC50 = 853 nM
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CP0556501
|
4-amino-N'-[(7R)-7-bicyclo[4.2.0]octa-1,3,5-trienyl]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C11H11N5O2
|
1
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| 1 |
IC50 = 853 nM
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CP0578025
|
1-[2-[bis(2-methylpropyl)amino]-5-[N'-(3-bromo-4-fluorophenyl)-N-hydroxycarbamimidoyl]phenyl]-3-pyrimidin-5-ylurea
Show/Hide
|
C26H31BrFN7O2
|
1
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| 1 |
IC50 = 860 nM
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CP0239393
|
O-[(3,5-dichlorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H12Cl3NO
|
1
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| 1 |
IC50 = 870 nM
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CP0060331
|
O-[[2-fluoro-3-(trifluoromethyl)phenyl]-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C14H12ClF4NO
|
1
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| 1 |
IC50 = 933 nM
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CP0060692
|
O-[(3-fluorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H13ClFNO
|
1
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| 1 |
IC50 = 939 nM
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CP0540195
|
4-Amino-N'-hydroxy-N-(3-methoxyphenyl)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C10H11N5O3
|
1
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| 1 |
IC50 = 970 nM
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CP0130138
|
4-amino-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C10H11N5O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0417938
|
3-[[5-chloro-2-(2H-triazol-4-ylamino)phenyl]methyl]cyclobutane-1-carboxylic acid
Show/Hide
|
C14H15ClN4O2
|
1
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| 1 |
IC50 = 1000 nM
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CP0566672
|
N-[[5-chloro-2-(2H-triazol-4-ylamino)phenyl]methyl]methanesulfonamide
Show/Hide
|
C10H12ClN5O2S
|
1
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| 1 |
IC50 = 1000 nM
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CP0566942
|
3-[4-(2-tert-butylphenoxy)-3-[(2-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C31H30N2O4
|
1
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| 1 |
IC50 = 1000 nM
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CP0238482
|
(E)-3-[4-[bis(2-methylpropyl)amino]-3-[[(E)-(4-chlorophenyl)methylideneamino]carbamoylamino]phenyl]but-2-enoic acid
Show/Hide
|
C26H33ClN4O3
|
1
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| 1 |
IC50 = 1020 nM
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CP0219363
|
N-[2-(dimethylamino)ethyl]-8-methylsulfanyl-5,12-dioxoindolizino[2,3-g]quinoline-6-carboxamide
Show/Hide
|
C21H20N4O3S
|
1
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| 1 |
IC50 = 1083 nM
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CP0060322
|
O-[bis(4-chlorophenyl)methyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H12Cl3NO
|
1
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| 1 |
IC50 = 1090 nM
|
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CP0326779
|
O-[[2-fluoro-5-(trifluoromethyl)phenyl]-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C14H12ClF4NO
|
1
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| 1 |
IC50 = 1090 nM
|
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CP0239395
|
O-[(2-methoxyphenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C14H16ClNO2
|
1
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| 1 |
IC50 = 1110 nM
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CP0577749
|
1-[4-(6-methylpyridin-3-yl)phenyl]-N-propylcyclobutane-1-carboxamide
Show/Hide
|
C20H24N2O
|
1
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| 1 |
IC50 = 1167 nM
|
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CP0357003
|
O-[(2,4-difluorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H12ClF2NO
|
1
|
| 1 |
IC50 = 1210 nM
|
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CP0189118
|
N-[2-(dimethylamino)ethyl]-5,12-dioxoindolizino[3,2-g]quinoline-11-carboxamide
Show/Hide
|
C20H18N4O3
|
1
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| 1 |
IC50 = 1235 nM
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CP0444802
|
5-cyclopentyl-6-fluoro-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C15H15FN2
|
1
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| 1 |
IC50 = 1239 nM
|
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CP0060324
|
O-[(2-fluorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H13ClFNO
|
1
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| 1 |
IC50 = 1260 nM
|
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CP0573546
|
1-[2-[bis(2-methylpropyl)amino]-5-[N'-(3-bromo-4-fluorophenyl)-N-hydroxycarbamimidoyl]phenyl]-3-cyclohexylurea
Show/Hide
|
C28H39BrFN5O2
|
1
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| 1 |
IC50 = 1340 nM
|
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CP0580021
|
1-[2-[bis(2-methylpropyl)amino]-5-[N-hydroxy-N'-(4-methylphenyl)carbamimidoyl]phenyl]-3-(4-methylphenyl)urea
Show/Hide
|
C30H39N5O2
|
1
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| 1 |
IC50 = 1340 nM
|
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CP0060323
|
5-aminooxy-5-(3-chlorophenyl)-N-phenylpentanamide;hydrochloride
Show/Hide
|
C17H20Cl2N2O2
|
1
|
| 1 |
IC50 = 1430 nM
|
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CP0326780
|
O-[(2-bromophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H13BrClNO
|
1
|
| 1 |
IC50 = 1460 nM
|
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CP0499151
|
4-Amino-N-(2-chlorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C9H8ClN5O2
|
1
|
| 1 |
IC50 = 1500 nM
|
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CP0479882
|
3-[4-(2-tert-butylphenoxy)-3-(phenylcarbamoylamino)phenyl]benzoic acid
Show/Hide
|
C30H28N2O4
|
1
|
| 1 |
IC50 = 1500 nM
|
|
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CP0579210
|
(7S)-7-hydroxy-1-(hydroxymethyl)-6,6-dimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione
Show/Hide
|
C19H18O5
|
1
|
| 1 |
IC50 = 1670 nM
|
|
|
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CP0239397
|
O-[bis(4-fluorophenyl)methyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H12ClF2NO
|
1
|
| 1 |
IC50 = 1680 nM
|
|
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CP0547729
|
4-[4-[4-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)piperidin-1-yl]phenyl]morpholine
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 1712 nM
|
|
|
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CP0179109
|
O-[phenyl-[3-(trifluoromethyl)phenyl]methyl]hydroxylamine;hydrochloride
Show/Hide
|
C14H13ClF3NO
|
1
|
| 1 |
IC50 = 1730 nM
|
|
|
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CP0382819
|
2-[aminooxy-(4-chlorophenyl)methyl]-5-methylphenol;hydrochloride
Show/Hide
|
C14H15Cl2NO2
|
1
|
| 1 |
IC50 = 1760 nM
|
|
|
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CP0539281
|
3-[4-(2-tert-butylphenoxy)-3-[(4-methoxyphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C31H30N2O5
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
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CP0539282
|
3-[4-(2-tert-butylphenoxy)-3-[(4-chlorophenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C30H27ClN2O4
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
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CP0341828
|
1-[(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)methyl]piperidine-3-carboxylic acid
Show/Hide
|
C22H18FN3O4
|
1
|
| 1 |
IC50 = 1840 nM
|
|
|
|
CP0188710
|
O-[(2,3-dichlorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H12Cl3NO
|
1
|
| 1 |
IC50 = 1870 nM
|
|
|
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CP0431574
|
8-fluoro-2-(4-methylpiperazin-1-yl)indolo[2,1-b]quinazoline-6,12-dione
Show/Hide
|
C20H17FN4O2
|
1
|
| 1 |
IC50 = 1870 nM
|
|
|
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CP0576805
|
[(7S)-1-(hydroxymethyl)-6,6-dimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-7-yl] acetate
Show/Hide
|
C21H20O6
|
1
|
| 1 |
IC50 = 1870 nM
|
|
|
|
CP0060327
|
O-[(3,4-dichlorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H12Cl3NO
|
1
|
| 1 |
IC50 = 1910 nM
|
|
|
|
CP0537449
|
(E)-3-[4-[bis(2-methylpropyl)amino]-3-[[(E)-(2-fluorophenyl)methylideneamino]carbamoylamino]phenyl]but-2-enoic acid
Show/Hide
|
C26H33FN4O3
|
1
|
| 1 |
IC50 = 1950 nM
|
|
|
|
CP0060691
|
O-[(2,4-dichlorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H12Cl3NO
|
1
|
| 1 |
IC50 = 1990 nM
|
|
|
|
CP0573547
|
1-[2-[bis(2-methylpropyl)amino]-5-[N'-(3-bromo-4-fluorophenyl)-N-hydroxycarbamimidoyl]phenyl]-3-[4-(trifluoromethyl)phenyl]urea
Show/Hide
|
C29H32BrF4N5O2
|
1
|
| 1 |
IC50 = 2090 nM
|
|
|
|
CP0567233
|
2-methoxy-5-[4-(2-methoxyphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C29H26N2O6
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0470964
|
2-(4-chloro-2-methylanilino)-N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]butanamide
Show/Hide
|
C22H22ClN3O2
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0563302
|
2-(4-chloro-2-methylanilino)-N-[(E)-naphthalen-1-ylmethylideneamino]butanamide
Show/Hide
|
C22H22ClN3O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0482370
|
8-fluoro-2-piperidin-1-ylindolo[2,1-b]quinazoline-6,12-dione
Show/Hide
|
C20H16FN3O2
|
1
|
| 1 |
IC50 = 2240 nM
|
|
|
|
CP0275023
|
4-Amino-N-(4-chlorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C9H8ClN5O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0428966
|
5-[4-[2-(1-hydroxy-2-methylpropan-2-yl)phenoxy]-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-methoxybenzoic acid
Show/Hide
|
C32H32N2O6
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0562841
|
5-[4-(2-tert-butylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-chlorobenzoic acid
Show/Hide
|
C31H29ClN2O4
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0550329
|
[(7S)-7-hydroxy-6,6-dimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-1-yl]methyl acetate
Show/Hide
|
C21H20O6
|
1
|
| 1 |
IC50 = 2420 nM
|
|
|
|
CP0060332
|
O-[(2-chlorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H13Cl2NO
|
1
|
| 1 |
IC50 = 2480 nM
|
|
|
|
CP0350803
|
1-(hydroxymethyl)-6,6-dimethylnaphtho[1,2-g][1]benzofuran-7,10,11-trione
Show/Hide
|
C19H14O5
|
1
|
| 1 |
IC50 = 2560 nM
|
|
|
|
CP0569153
|
3-[4-(2-tert-butylphenoxy)-3-[[4-(difluoromethoxy)phenyl]carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C31H28F2N2O5
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0260915
|
1-[2-[bis(2-methylpropyl)amino]-5-[N'-(3-bromo-4-fluorophenyl)-N-hydroxycarbamimidoyl]phenyl]-3-propylurea
Show/Hide
|
C25H35BrFN5O2
|
1
|
| 1 |
IC50 = 2610 nM
|
|
|
|
CP0124065
|
N-(2-methylphenyl)-5,12-dioxoindolizino[3,2-g]quinoline-11-carboxamide
Show/Hide
|
C23H15N3O3
|
1
|
| 1 |
IC50 = 2662 nM
|
|
|
|
CP0362076
|
(E)-3-[4-(dibutylamino)-3-[[(E)-[2-(trifluoromethyl)phenyl]methylideneamino]carbamoylamino]phenyl]but-2-enoic acid
Show/Hide
|
C27H33F3N4O3
|
1
|
| 1 |
IC50 = 2830 nM
|
|
|
|
CP0365962
|
4-[aminooxy(phenyl)methyl]phenol;hydrochloride
Show/Hide
|
C13H14ClNO2
|
1
|
| 1 |
IC50 = 2890 nM
|
|
|
|
CP0457257
|
3-[3-[(4-bromophenyl)carbamoylamino]-4-(2-tert-butylphenoxy)phenyl]benzoic acid
Show/Hide
|
C30H27BrN2O4
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0482369
|
2-(4-methylpiperazin-1-yl)indolo[2,1-b]quinazoline-6,12-dione
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
IC50 = 2960 nM
|
|
|
|
CP0323384
|
1-[(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)methyl]piperidine-4-carboxylic acid
Show/Hide
|
C22H18FN3O4
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0528081
|
1-[2-[bis(2-methylpropyl)amino]-5-[N'-(3-bromo-4-fluorophenyl)-N-hydroxycarbamimidoyl]phenyl]-3-butylurea
Show/Hide
|
C26H37BrFN5O2
|
1
|
| 1 |
IC50 = 3110 nM
|
|
|
|
CP0470492
|
N-(4-methoxyphenyl)-2-[5-(4-methylphenyl)-4-oxothieno[2,3-d]pyrimidin-3-yl]acetamide
Show/Hide
|
C22H19N3O3S
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0060326
|
O-[[3,5-bis(trifluoromethyl)phenyl]-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C15H12ClF6NO
|
1
|
| 1 |
IC50 = 3350 nM
|
|
|
|
CP0060689
|
O-[phenyl(thiophen-3-yl)methyl]hydroxylamine;hydrochloride
Show/Hide
|
C11H12ClNOS
|
1
|
| 1 |
IC50 = 3360 nM
|
|
|
|
CP0359319
|
1-[(8-fluoro-6,12-dioxoindolo[2,1-b]quinazolin-2-yl)methyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C21H16FN3O4
|
1
|
| 1 |
IC50 = 3760 nM
|
|
|
|
CP0471021
|
1-methyl-N-[4-[1-(propylcarbamoyl)cyclobutyl]phenyl]triazole-4-carboxamide
Show/Hide
|
C18H23N5O2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0155221
|
(E)-3-[3-[[(E)-(4-chlorophenyl)methylideneamino]carbamoylamino]-4-(dibutylamino)phenyl]but-2-enoic acid
Show/Hide
|
C26H33ClN4O3
|
1
|
| 1 |
IC50 = 3870 nM
|
|
|
|
CP0248477
|
3-[4-(2-tert-butylphenoxy)-3-[[4-(trifluoromethoxy)phenyl]carbamoylamino]phenyl]benzoic acid
Show/Hide
|
C31H27F3N2O5
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0562840
|
3-[4-(2-tert-butylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-fluorobenzoic acid
Show/Hide
|
C31H29FN2O4
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0468917
|
N-[(E)-(2-hydroxy-6-nitronaphthalen-1-yl)methylideneamino]-2-phenylacetamide
Show/Hide
|
C19H15N3O4
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0469380
|
N-(1,3-benzodioxol-5-yl)-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
|
C19H15N3O3
|
1
|
| 1 |
IC50 = 5030 nM
|
|
|
|
CP0578579
|
[(7S)-1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-7-yl] methanesulfonate
Show/Hide
|
C20H20O6S
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0462336
|
6-fluoro-5-(oxan-4-yl)-5H-imidazo[5,1-a]isoindole
Show/Hide
|
C15H15FN2O
|
1
|
| 1 |
IC50 = 5344 nM
|
|
|
|
CP0468916
|
2-[5-(3,4-dimethoxyphenyl)-4-oxothieno[2,3-d]pyrimidin-3-yl]-N-(4-methoxyphenyl)acetamide
Show/Hide
|
C23H21N3O5S
|
1
|
| 1 |
IC50 = 5600 nM
|
|
|
|
CP0575903
|
5-[4-(2-cyanophenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]-2-methoxybenzoic acid
Show/Hide
|
C29H23N3O5
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0559419
|
2-(4-chlorophenyl)sulfanyl-N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]acetamide
Show/Hide
|
C19H15ClN2O2S
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0523473
|
5-chloro-3-[(4-chlorophenyl)methyl]-1,3-benzoxazol-2-one
Show/Hide
|
C14H9Cl2NO2
|
1
|
| 1 |
IC50 = 6080 nM
|
|
|
|
CP0417471
|
5-chloro-3-[2-(4-fluorophenyl)acetyl]-1,3-benzoxazol-2-one
Show/Hide
|
C15H9ClFNO3
|
1
|
| 1 |
IC50 = 6400 nM
|
|
|
|
CP0179152
|
O-[3-(3-chlorophenyl)-1-phenylpropyl]hydroxylamine;hydrochloride
Show/Hide
|
C15H17Cl2NO
|
1
|
| 1 |
IC50 = 6740 nM
|
|
|
|
CP0514501
|
4-Amino-N-(3-tert-butylphenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
|
C13H17N5O2
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
|
CP0243947
|
O-[(4-chlorophenyl)-phenylmethyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H13Cl2NO
|
1
|
| 1 |
IC50 = 7150 nM
|
|
|
|
CP0577698
|
N-propyl-1-(4-pyridin-3-ylphenyl)cyclobutane-1-carboxamide
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
IC50 = 8017 nM
|
|
|
|
CP0578577
|
6,6-dimethyl-7,10,11-trioxonaphtho[1,2-g][1]benzofuran-1-carboxylic acid
Show/Hide
|
C19H12O6
|
1
|
| 1 |
IC50 = 8550 nM
|
|
|
|
CP0220146
|
N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-2-(2-methoxyanilino)acetamide
Show/Hide
|
C20H19N3O3
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0579362
|
1,6,6-trimethylnaphtho[1,2-g][1]benzofuran-7,10,11-trione
Show/Hide
|
C19H14O4
|
1
|
| 1 |
IC50 = 9330 nM
|
|
|
|
CP0335170
|
5-chloro-3-[(3-fluorophenyl)methyl]-1,3-benzoxazol-2-one
Show/Hide
|
C14H9ClFNO2
|
1
|
| 1 |
IC50 = 9750 nM
|
|
|
|
CP0540069
|
5-methyl-N-[4-[1-(propylcarbamoyl)cyclobutyl]phenyl]-1,2-oxazole-4-carboxamide
Show/Hide
|
C19H23N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0569754
|
N-propyl-1-(4-pyridin-2-ylphenyl)cyclobutane-1-carboxamide
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0569755
|
N-propyl-1-(4-pyridin-4-ylphenyl)cyclobutane-1-carboxamide
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0545404
|
3-Hydroxytanshinone
Show/Hide
|
C19H18O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0569181
|
N,N-diethyl-6,6-dimethyl-7,10,11-trioxonaphtho[1,2-g][1]benzofuran-1-carboxamide
Show/Hide
|
C23H21NO5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0569394
|
8-hydroxy-1,6,6-trimethylnaphtho[1,2-g][1]benzofuran-9,10,11-trione
Show/Hide
|
C19H14O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0576804
|
PRZEWAQUINONE A
Show/Hide
|
C19H18O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0578083
|
9-bromo-1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione
Show/Hide
|
C19H17BrO3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0579187
|
1,6,6-trimethyl-8,9-dihydronaphtho[1,2-g][1]benzofuran-7,10,11-trione
Show/Hide
|
C19H16O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0579211
|
8-hydroxy-1,6,6-trimethyl-7,8-dihydronaphtho[1,2-g][1]benzofuran-9,10,11-trione
Show/Hide
|
C19H16O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0579363
|
[(7S)-1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-7-yl] acetate
Show/Hide
|
C21H20O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0558606
|
5-chloro-3-[2-(4-fluorophenyl)-2-hydroxyethyl]-1,3-benzoxazol-2-one
Show/Hide
|
C15H11ClFNO3
|
1
|
| 1 |
IC50 = 10200 nM
|
|
|
|
CP0542134
|
N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-2-(4-nitrophenyl)acetamide
Show/Hide
|
C19H15N3O4
|
1
|
| 1 |
IC50 = 10300 nM
|
|
|
|
CP0166896
|
N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-2-methoxybenzamide
Show/Hide
|
C19H16N2O3
|
1
|
| 1 |
IC50 = 11300 nM
|
|
|
|
CP0475619
|
2-[5-(4-chlorophenyl)-4-oxothieno[2,3-d]pyrimidin-3-yl]-N-(furan-2-ylmethyl)acetamide
Show/Hide
|
C19H14ClN3O3S
|
1
|
| 1 |
IC50 = 12400 nM
|
|
|
|
CP0565002
|
5-chloro-N-[(3-methoxyphenyl)methyl]-2-oxo-1,3-benzoxazole-3-carboxamide
Show/Hide
|
C16H13ClN2O4
|
1
|
| 1 |
IC50 = 14560 nM
|
|
|
|
CP0168477
|
1-Methyltryptophan, 1
Show/Hide
|
C12H14N2O2
|
1
|
| 1 |
IC50 = 14690 nM
|
|
|
|
CP0247994
|
O-[1-(2-fluorophenyl)-3-phenylpropyl]hydroxylamine;hydrochloride
Show/Hide
|
C15H17ClFNO
|
1
|
| 1 |
IC50 = 14700 nM
|
|
|
|
CP0427654
|
2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-(2-phenylethyl)acetamide
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
IC50 = 14980 nM
|
|
|
|
CP0511358
|
(2R,3R)-2-(3,4-dihydroxyphenyl)-3,6,7-trihydroxy-2,3-dihydrochromen-4-one
Show/Hide
|
C15H12O7
|
1
|
| 1 |
IC50 = 16300 nM
|
|
|
|
CP0565004
|
5-chloro-3-(2-phenylethyl)-1,3-benzoxazol-2-one
Show/Hide
|
C15H12ClNO2
|
1
|
| 1 |
IC50 = 17910 nM
|
|
|
|
CP0556638
|
2-[[3-[4-(4-chlorophenyl)-1H-pyrazol-5-yl]piperidin-1-yl]methyl]phenol
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
IC50 = 18600 nM
|
|
|
|
CP0176763
|
(E)-3-[3-[4-[(4-fluoroanilino)methyl]triazol-1-yl]-4-morpholin-4-ylphenyl]but-2-enoic acid
Show/Hide
|
C23H24FN5O3
|
1
|
| 1 |
IC50 = 20020 nM
|
|
|
|
CP0537640
|
2-[5-(4-methylphenyl)-4-oxothieno[2,3-d]pyrimidin-3-yl]-N-naphthalen-1-ylacetamide
Show/Hide
|
C25H19N3O2S
|
1
|
| 1 |
IC50 = 20100 nM
|
|
|
|
CP0489805
|
(Z)-1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol- 5-yl)ethanone oxime
Show/Hide
|
C18H21N3O
|
1
|
| 1 |
IC50 = 20370 nM
|
|
|
|
CP0402324
|
N-[[6-(4-bromophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl]methyl]-3-methoxyaniline
Show/Hide
|
C18H16BrN5OS
|
1
|
| 1 |
IC50 = 20600 nM
|
|
|
|
CP0558849
|
5-chloro-3-[2-(4-fluorophenyl)-2-oxoethyl]-1,3-benzoxazol-2-one
Show/Hide
|
C15H9ClFNO3
|
1
|
| 1 |
IC50 = 20680 nM
|
|
|
|
CP0179153
|
O-[cyclohexyl(phenyl)methyl]hydroxylamine;hydrochloride
Show/Hide
|
C13H20ClNO
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0426231
|
4-(dimethylamino)-N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]benzamide
Show/Hide
|
C20H19N3O2
|
1
|
| 1 |
IC50 = 21100 nM
|
|
|
|
CP0564891
|
2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-(2-pyridin-2-ylethyl)acetamide
Show/Hide
|
C19H18N4O
|
1
|
| 1 |
IC50 = 21930 nM
|
|
|
|
CP0558889
|
(NZ)-N-[1-(4-chlorophenyl)-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethylidene]hydroxylamine
Show/Hide
|
C18H14ClN3O
|
1
|
| 1 |
IC50 = 22720 nM
|
|
|
|
CP0476638
|
1-(2-aminobenzimidazol-1-yl)-2-(4-fluorophenyl)ethanone
Show/Hide
|
C15H12FN3O
|
1
|
| 1 |
IC50 = 22730 nM
|
|
|
|
CP0476677
|
5-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-1,3-benzoxazol-2-one
Show/Hide
|
C15H9Cl2NO3
|
1
|
| 1 |
IC50 = 24920 nM
|
|
|
|
CP0545850
|
2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-phenylacetamide
Show/Hide
|
C18H15N3O
|
1
|
| 1 |
IC50 = 25930 nM
|
|
|
|
CP0468919
|
N-[(E)-(4-ethoxyphenyl)methylideneamino]-2-hydroxynaphthalene-1-carboxamide
Show/Hide
|
C20H18N2O3
|
1
|
| 1 |
IC50 = 27300 nM
|
|
|
|
CP0558610
|
5-fluoro-3-[(3-fluorophenyl)methyl]-1,3-benzoxazol-2-one
Show/Hide
|
C14H9F2NO2
|
1
|
| 1 |
IC50 = 28490 nM
|
|
|
|
CP0125581
|
1-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-3-phenylurea
Show/Hide
|
C18H15N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0202784
|
N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-2-(2-methoxy-N-methylsulfonylanilino)acetamide
Show/Hide
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C21H21N3O5S
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1
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| 1 |
IC50 > 30000 nM
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CP0402369
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2-(2,4-dimethylphenoxy)-N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]acetamide
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C21H20N2O3
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1
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| 1 |
IC50 > 30000 nM
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CP0443938
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3-(2,3-dihydroindol-1-ylmethyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
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C19H17N5S
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1
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| 1 |
IC50 > 30000 nM
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CP0470966
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2-(4-oxo-5-phenylthieno[2,3-d]pyrimidin-3-yl)-N-(phenylcarbamoyl)acetamide
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C21H16N4O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0475620
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N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-2-(4-methoxyphenyl)acetamide
Show/Hide
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C20H18N2O3
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1
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| 1 |
IC50 > 30000 nM
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CP0475622
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N-ethyl-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]oxamide
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C15H15N3O3
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1
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| 1 |
IC50 > 30000 nM
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CP0491751
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3-methoxy-N-[[6-(3-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl]methyl]aniline
Show/Hide
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C19H19N5O2S
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1
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| 1 |
IC50 > 30000 nM
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CP0536320
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N-(benzylcarbamoyl)-2-[5-(4-fluorophenyl)-4-oxothieno[2,3-d]pyrimidin-3-yl]acetamide
Show/Hide
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C22H17FN4O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0550947
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1-[(E)-(1,3-thiazol-2-ylhydrazinylidene)methyl]naphthalen-2-ol
Show/Hide
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C14H11N3OS
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1
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| 1 |
IC50 > 30000 nM
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CP0556539
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4-ethoxy-N-[(6-thiophen-2-yl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl)methyl]aniline
Show/Hide
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C17H17N5OS2
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1
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| 1 |
IC50 > 30000 nM
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CP0478555
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3-[(3-fluorophenyl)methyl]-1,3-benzoxazol-2-one
Show/Hide
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C14H10FNO2
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1
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| 1 |
IC50 = 30800 nM
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CP0558609
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N-[(4-methoxyphenyl)methyl]-2-oxo-1,3-benzoxazole-3-carboxamide
Show/Hide
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C16H14N2O4
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1
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| 1 |
IC50 = 31820 nM
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CP0564818
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2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-(1H-indazol-6-yl)acetamide
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C19H15N5O
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1
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| 1 |
IC50 = 33100 nM
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CP0513862
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3-[(4-chlorophenyl)methyl]-1,3-benzoxazol-2-one
Show/Hide
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C14H10ClNO2
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1
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| 1 |
IC50 = 34960 nM
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CP0523475
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3-[2-(4-chlorophenyl)-2-oxoethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H10ClNO3
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1
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| 1 |
IC50 = 38610 nM
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CP0427652
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N-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
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C18H21N3O
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1
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| 1 |
IC50 = 39040 nM
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CP0564038
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3-[2-(3-chlorophenyl)-2-oxoethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H10ClNO3
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1
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| 1 |
IC50 = 49250 nM
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CP0457236
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3-[2-(4-fluorophenyl)-2-hydroxyethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H12FNO3
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1
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| 1 |
IC50 = 49340 nM
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CP0513863
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3-[2-(4-chlorophenyl)-2-hydroxyethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H12ClNO3
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1
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| 1 |
IC50 = 50810 nM
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CP0473802
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N-[(3-chloro-4-fluorophenyl)methyl]-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
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C19H15ClFN3O
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1
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| 1 |
IC50 = 50900 nM
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CP0466115
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3-[2-(4-fluorophenyl)-2-oxoethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H10FNO3
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1
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| 1 |
IC50 = 53130 nM
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CP0547376
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N-[(3-chlorophenyl)methyl]-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
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C19H16ClN3O
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1
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| 1 |
IC50 = 53930 nM
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CP0427650
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N-[(3,4-difluorophenyl)methyl]-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
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C19H15F2N3O
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1
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| 1 |
IC50 = 58110 nM
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CP0391283
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N-benzyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
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C19H17N3O
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1
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| 1 |
IC50 = 60560 nM
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CP0564037
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5-chloro-3-[2-(3-chlorophenyl)-2-hydroxyethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H11Cl2NO3
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1
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| 1 |
IC50 = 60880 nM
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CP0523474
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5-chloro-3-[2-(4-chlorophenyl)-2-hydroxyethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H11Cl2NO3
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1
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| 1 |
IC50 = 62660 nM
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CP0545849
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N-benzyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-methylacetamide
Show/Hide
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C20H19N3O
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1
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| 1 |
IC50 = 64470 nM
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CP0558888
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2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-(pyrazin-2-ylmethyl)acetamide
Show/Hide
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C17H15N5O
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1
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| 1 |
IC50 = 65920 nM
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CP0391284
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N-(1,3-benzodioxol-5-ylmethyl)-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
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C20H17N3O3
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1
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| 1 |
IC50 = 66730 nM
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CP0547454
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N-[(4-cyanophenyl)methyl]-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
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C20H16N4O
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1
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| 1 |
IC50 = 69440 nM
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CP0529167
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N-[(4-hydroxyphenyl)methyl]-2-(5H-imidazo[5,1-a]isoindol-5-yl)acetamide
Show/Hide
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C19H17N3O2
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1
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| 1 |
IC50 = 71700 nM
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CP0427651
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2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-(1-phenylethyl)acetamide
Show/Hide
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C20H19N3O
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1
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| 1 |
IC50 = 74390 nM
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CP0565006
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5-chloro-3-[2-(3-chlorophenyl)-2-oxoethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H9Cl2NO3
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1
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| 1 |
IC50 = 76580 nM
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CP0071950
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(S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Show/Hide
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C12H14N2O2
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1
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| 1 |
IC50 = 77290 nM
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CP0547377
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2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-[(4-methoxyphenyl)methyl]acetamide
Show/Hide
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C20H19N3O2
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1
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| 1 |
IC50 = 77540 nM
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CP0565005
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3-[2-(3-chlorophenyl)-2-hydroxyethyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H12ClNO3
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1
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| 1 |
IC50 = 80580 nM
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CP0517708
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3-[(4-chlorophenyl)methyl]-5-fluoro-1,3-benzoxazol-2-one
Show/Hide
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C14H9ClFNO2
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1
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| 1 |
IC50 = 80780 nM
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CP0549079
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2-(5H-imidazo[5,1-a]isoindol-5-yl)-N-(pyridin-3-ylmethyl)acetamide
Show/Hide
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C18H16N4O
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1
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| 1 |
IC50 = 82120 nM
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CP0558835
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3-benzoyl-1,3-benzoxazol-2-one
Show/Hide
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C14H9NO3
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1
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| 1 |
IC50 = 90490 nM
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CP0558887
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4-[[[2-(5H-imidazo[5,1-a]isoindol-5-yl)acetyl]amino]methyl]benzoic acid
Show/Hide
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C20H17N3O3
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1
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| 1 |
IC50 = 95070 nM
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CP0565003
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3-[(4-chlorophenyl)methyl]-5-nitro-1,3-benzoxazol-2-one
Show/Hide
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C14H9ClN2O4
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1
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| 1 |
IC50 = 99350 nM
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CP0541154
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3-[(3-fluorophenyl)methyl]-5-nitro-1,3-benzoxazol-2-one
Show/Hide
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C14H9FN2O4
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1
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| 1 |
IC50 = 99830 nM
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CP0564036
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3-[2-(4-fluorophenyl)-2-hydroxyethyl]-1H-benzimidazol-2-one
Show/Hide
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C15H13FN2O2
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1
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| 1 |
IC50 = 99940 nM
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CP0476639
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5-chloro-N-(4-methoxyphenyl)-2-oxo-1,3-benzoxazole-3-carboxamide
Show/Hide
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C15H11ClN2O4
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1
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| 1 |
IC50 > 100000 nM
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CP0517709
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3-(2-phenylethyl)-1,3-benzoxazol-2-one
Show/Hide
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C15H13NO2
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1
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| 1 |
IC50 > 100000 nM
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CP0523472
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5-amino-3-[(3-fluorophenyl)methyl]-1,3-benzoxazol-2-one
Show/Hide
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C14H11FN2O2
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1
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| 1 |
IC50 > 100000 nM
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CP0562589
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3-[2-(4-fluorophenyl)acetyl]-1,3-benzoxazol-2-one
Show/Hide
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C15H10FNO3
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1
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| 1 |
IC50 > 100000 nM
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CP0472241
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N'-(3-bromo-4-fluorophenyl)-4-[[1-[ethoxy(propyl)phosphoryl]piperidin-4-yl]amino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C19H27BrFN6O4P
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1
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| 1 |
IC50 > 200 nM
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CP0563028
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N'-(3-bromo-4-fluorophenyl)-4-[[1-[ethoxy(methyl)phosphoryl]piperidin-4-yl]amino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C17H23BrFN6O4P
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1
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| 1 |
IC50 > 200 nM
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CP0565152
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N'-(3-bromo-4-fluorophenyl)-4-[[1-[ethoxy(ethyl)phosphoryl]piperidin-4-yl]amino]-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C18H25BrFN6O4P
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1
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| 1 |
IC50 > 200 nM
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CP0482139
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2-[4-[bis(2-methylpropyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]-N-(trifluoromethylsulfonyl)benzamide
Show/Hide
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C30H35F3N4O4S
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1
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| 1 |
IC50 > 1000 nM
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CP0545970
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4-[4-(2-tert-butylphenoxy)-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C31H30N2O4
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1
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| 1 |
IC50 > 1000 nM
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CP0545972
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1-[2-[bis(2-methylpropyl)amino]-5-[2-(methanesulfonamido)phenyl]phenyl]-3-(4-methylphenyl)urea
Show/Hide
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C29H38N4O3S
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1
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| 1 |
IC50 > 1000 nM
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CP0569155
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2-[4-[bis(2-methoxyethyl)amino]-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C27H31N3O5
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1
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| 1 |
IC50 > 1000 nM
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CP0574847
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2-[4-(2-tert-butyl-N-methylanilino)-3-[(4-methylphenyl)carbamoylamino]phenyl]benzoic acid
Show/Hide
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C32H33N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0470716
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N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[3-[[methoxy(methyl)phosphoryl]amino]piperidin-1-yl]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C16H21BrFN6O4P
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1
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| 1 |
IC50 > 1000 nM
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CP0561229
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N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[4-[methoxy(methyl)phosphoryl]piperazin-1-yl]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C15H19BrFN6O4P
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1
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| 1 |
IC50 > 1000 nM
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CP0561230
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N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-[4-[[methoxy(methyl)phosphoryl]amino]piperidin-1-yl]-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C16H21BrFN6O4P
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1
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| 1 |
IC50 > 1000 nM
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CP0222140
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4-Amino-N-(3-chlorophenyl)-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C9H8ClN5O
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1
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| 1 |
IC50 > 2000 nM
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CP0401243
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4-Aamino-N-(3-chlorophenyl)-N'-methoxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C10H10ClN5O2
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1
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| 1 |
IC50 > 2000 nM
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CP0499154
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4-Amino-N-(3-chlorophenyl)-1,2,5-oxadiazole-3-carboxamide
Show/Hide
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C9H7ClN4O2
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1
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| 1 |
IC50 > 2000 nM
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CP0502842
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4-Amino-N-(3-chlorophenyl)-1,2,5-oxadiazole-3-carbohydrazonamide
Show/Hide
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C9H9ClN6O
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1
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| 1 |
IC50 > 2000 nM
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CP0514502
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4-Amino-N-(3-chlorophenyl)-1,2,5-oxadiazole-3-carbothioamide
Show/Hide
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C9H7ClN4OS
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1
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| 1 |
IC50 > 2000 nM
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CP0558925
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N'-(3-bromo-4-fluorophenyl)-4-(dimethylamino)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Show/Hide
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C11H11BrFN5O2
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1
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| 1 |
IC50 > 5000 nM
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