Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1- a]isoindol-5-yl)-1-hydroxyethyl)cyclohexanol
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Canonical SMILES
O[C@H](C[C@H]1c2c(cccc2F)-c2cncn12)[C@H]1CC[C@H](O)CC1
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Compound Formula C18H21FN2O2
Compound Structure
Protein Name
 Protein Info 
Indoleamine 2,3-dioxygenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P14902
Gene Name
IDO1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 434 nM
   TI
   LI
   LO
   TS
CL000058 T-REx-293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 75 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM
2 IC50 = 28 nM
3 IC50 = 75 nM
4 IC50 = 450 nM
5 Ki = 5.8 nM
6 Ki = 19 nM
7 Ki = 28 nM