Brief Information of the Compound and Protein
Compound Name
1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol
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PubChem ID
CID: 66558287
SID: 152188703
Canonical SMILES
OC(CC1c2ccccc2-c2cncn12)C1CCCCC1
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Compound Formula C18H22N2O
Compound Structure
Protein Name
Indoleamine 2,3-dioxygenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P14902
Gene Name
IDO1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  3
1
EC50 = 61 nM
   TI
   LI
   LO
   TS
2
IC50 = 190 nM
   TI
   LI
   LO
   TS
3
IC50 = 410 nM
   TI
   LI
   LO
   TS
CL000979 LLTC Mus musculus (Mouse)  1
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
CL000058 T-REx-293 Homo sapiens (Human)  1
1
EC50 = 83 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 28 nM
2 IC50 = 38 nM
3 IC50 = 50 nM
4 IC50 = 60 nM
5 IC50 < 1000 nM
6 Kd = 3300 nM
7 Ki = 7 nM
8 Ki = 7.2 nM