Brief Information of the Compound and Protein
Compound Name
N-(4-fluorophenyl)-1-[1-[2-(trifluoromethyl)pyrimidin-4-yl]-2,3-dihydropyrrolo[3,2-b]pyridin-5-yl]cyclobutane-1-carboxamide
    Show/Hide
Canonical SMILES
Fc1ccc(NC(=O)C2(CCC2)c2ccc3N(CCc3n2)c2ccnc(n2)C(F)(F)F)cc1
    Show/Hide
Compound Formula C23H19F4N5O
Compound Structure
Protein Name
Indoleamine 2,3-dioxygenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P14902
Gene Name
IDO1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 127 nM
   TI
   LI
   LO
   TS