| Compound ID |
Compound Name |
Compound Formula |
|
CP0373796
|
3-[7-[2-methyl-4-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C30H28N6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0374016
|
2-fluoro-5-[7-[2-methyl-4-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C30H27FN6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0383792
|
2-chloro-5-[7-[4-(8-methyl-3,8-diazabicyclo[3.2.1]octan-3-yl)phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C30H27ClN6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0485281
|
5-[7-[4-[(1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]-2-fluorophenol
Show/Hide
|
C28H23FN6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0489649
|
3-[7-[2-chloro-4-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C29H25ClN6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0494168
|
3-[7-[4-[(1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-methylphenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C29H26N6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0497568
|
3-[7-[2-fluoro-4-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C29H25FN6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0528647
|
3-[7-[4-[(1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-fluorophenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C28H23FN6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0536412
|
2-fluoro-5-[7-[4-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C29H25FN6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0543126
|
3-[7-[2-chloro-4-[(1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl]-2-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl]phenol
Show/Hide
|
C28H23ClN6O
|
1
|
| 1 |
IC50 < 0.32 nM
|
|
|
|
CP0039596
|
3-(7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol
Show/Hide
|
C29H26N6O
|
1
|
| 1 |
IC50 = 0.38 nM
|
|
|
|
CP0374018
|
7-(4-((1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl)-2-fluorophenyl)-3-(3-methoxyphenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C29H25FN6O
|
1
|
| 1 |
IC50 = 0.44 nM
|
|
|
|
CP0471461
|
3-(7-(4-((1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol
Show/Hide
|
C28H24N6O
|
1
|
| 1 |
IC50 = 0.49 nM
|
|
|
|
CP0485282
|
1-((1S,4S)-5-(4-(3-(4-fluoro-3-hydroxyphenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)ethanone
Show/Hide
|
C30H25FN6O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0510478
|
5-(7-(4-((1S,4S)-5-ethyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-2-fluorophenol
Show/Hide
|
C30H27FN6O
|
1
|
| 1 |
IC50 = 0.51 nM
|
|
|
|
CP0499468
|
3-(3-hydroxyphenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C30H28N6O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0485378
|
(R)-3-(2-(pyridin-4-yl)-7-(4-(quinuclidin-3-ylamino)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol
Show/Hide
|
C30H28N6O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0528649
|
3-(4-fluoro-3-methoxyphenyl)-7-(2-methyl-4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C31H29FN6O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0403551
|
N-methyl-4-[2-(4-propan-2-ylanilino)quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0543125
|
(S)-3-(2-(pyridin-4-yl)-7-(4-(quinuclidin-3-ylamino)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol
Show/Hide
|
C30H28N6O
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0510477
|
3-(2-(pyridin-4-yl)-7-(4-(quinuclidin-4-ylmethylamino)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol
Show/Hide
|
C31H30N6O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0029366
|
US8497274, 32
Show/Hide
|
C27H18F4N4O3S
|
2
|
| 1 |
IC50 = 3.23 nM
|
|
|
| 2 |
IC50 = 4.48 nM
|
|
|
|
CP0897184
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-trifluoromethylthio-benzamide
Show/Hide
|
C21H14F3N3O3S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0346327
|
N-[5-[[7-cyano-2-[[2-(2-methoxyethoxy)acetyl]amino]-1,3-benzothiazol-6-yl]oxy]-2-fluorophenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C28H22F4N4O5S
|
1
|
| 1 |
IC50 = 5.75 nM
|
|
|
|
CP0525085
|
N-[3-[(6-chloro-1,3-dioxoisoindol-5-yl)amino]phenyl]-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H13ClF3N3O4
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0039590
|
3-(trifluoromethoxy)-N-[2,3,4-trifluoro-5-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]phenyl]benzamide
Show/Hide
|
C21H11F6N3O4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0375310
|
N-[3-[(6-chloro-1,3-dioxoisoindol-5-yl)amino]phenyl]-3-iodobenzamide
Show/Hide
|
C21H13ClIN3O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0393604
|
N-[3-[(7-chloro-1,4-dioxo-2,3-dihydrophthalazin-6-yl)amino]phenyl]-3-iodobenzamide
Show/Hide
|
C21H14ClIN4O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0528648
|
3-(3-methoxyphenyl)-7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C30H28N6O
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0497570
|
7-(4-((1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(4-fluoro-3-methoxyphenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C29H25FN6O
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0540416
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalen-1-ol
Show/Hide
|
C28H26N4O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0382811
|
2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-[(4-methylphenyl)diazenyl]benzamide
Show/Hide
|
C21H16F2N6O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0489648
|
3-(4-chloro-3-methoxyphenyl)-7-(4-(8-methyl-3,8-diazabicyclo[3.2.1]octan-3-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C31H29ClN6O
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0897173
|
N-(2,4-difluoro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H12F5N3O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0533236
|
N-[3-[(6-chloro-1,3-dioxoisoindol-5-yl)amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H13ClF3N3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0471462
|
7-(4-((1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-3-(3-methoxyphenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C29H26N6O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0943550
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H14F3N3O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0845261
|
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)urea
Show/Hide
|
C21H14ClF3N4O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0846914
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-fluoro-3-trifluoromethoxy-benzamide
Show/Hide
|
C21H13F4N3O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0910581
|
N-(5-chloro-6-methylpyridin-3-yl)-5-(3-(2-cyanopropan-2-yl)benzamido)-2-methylbenzamide
Show/Hide
|
C25H23ClN4O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0383791
|
3-(3-methoxyphenyl)-7-(4-(8-methyl-3,8-diazabicyclo[3.2.1]octan-3-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C31H30N6O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0846908
|
3-Tert-butyl-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C24H23N3O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0393605
|
N-[3-[(7-chloro-1,4-dioxo-2,3-dihydrophthalazin-6-yl)amino]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H14ClF3N4O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0438926
|
N-[4-fluoro-3-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H14F4N6O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0400734
|
N-[3-[(7-chloro-1,4-dioxo-2,3-dihydrophthalazin-6-yl)amino]phenyl]-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H14ClF3N4O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0525086
|
3-bromo-N-[3-[(7-chloro-1,4-dioxo-2,3-dihydrophthalazin-6-yl)amino]phenyl]benzamide
Show/Hide
|
C21H14BrClN4O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0666154
|
(R)-N-(1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)phenyl)-ethyl)acetamide
Show/Hide
|
C23H21N5O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0506173
|
N-[3-[3-[4-(pyrrolidin-1-ylmethyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C31H26F3N5O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0396593
|
N-[5-[[7-cyano-2-[[2-[2-[2-[2-oxo-2-(1,3-thiazol-2-ylamino)ethoxy]ethoxy]ethoxy]acetyl]amino]-1,3-benzothiazol-6-yl]oxy]-2-fluorophenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C34H28F4N6O7S2
|
1
|
| 1 |
IC50 = 20.3 nM
|
|
|
|
CP0537740
|
3-(4-fluoro-3-methoxyphenyl)-7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
Show/Hide
|
C30H27FN6O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0897183
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(1,1,2,2-tetrafluoroethoxy)benzamide
Show/Hide
|
C22H15F4N3O4
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0921843
|
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)urea
Show/Hide
|
C21H14ClF3N4O3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0873279
|
N-(2-Methoxyethyl)-4-{[6-(4-methylpyridin-3-yl)quinazolin-2-yl]amino}benzamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0165922
|
N-[3-[3-[4-[(dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H24F3N5O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0291996
|
4-[2-(3-tert-butylanilino)quinoxalin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0430674
|
N-[3-[3-[4-[2-(dimethylamino)ethyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H26F3N5O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0897170
|
1-(6-fluoro-3-(trifluoromethyl)phenyl)-3-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C21H14F4N4O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0205293
|
4-[2-(3-tert-butylanilino)quinolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0756961
|
3-Methoxy-N-((1R)-1-{4-[(6-pyridin-4-ylquinazolin-2-yl)-amino]phenyl}ethyl)propanamide
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0828634
|
N-(4-{[(2-Methoxyethyl)(methyl)amino]methyl}phenyl)-6-pyridin-4-ylquinazolin-2-amine
Show/Hide
|
C24H25N5O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0540415
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2-fluoronaphthalen-1-ol
Show/Hide
|
C28H25FN4O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0537789
|
N-[4-fluoro-3-[3-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H25F4N7O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0542632
|
N-[3-[3-[6-[2-(dimethylamino)ethylamino]pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H26F3N7O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0682225
|
3-Methoxy-N-methyl-N-(4-(6-(pyridin-4-yl)quinazolin-2-ylamino)phenyl)propanamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0402121
|
2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-[(4-methylphenyl)diazenyl]benzamide
Show/Hide
|
C21H16F2N6O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0897171
|
N-(3-chloro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13ClF3N3O4
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0917383
|
N-(3-fluoro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13F4N3O4
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0507156
|
N-[3-[3-[4-[[2-(dimethylamino)acetyl]amino]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H25F3N6O2
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0068741
|
3-(2-cyanopropan-2-yl)-N-[4-methyl-3-[(3-methyl-4-oxoquinazolin-6-yl)amino]phenyl]benzamide
Show/Hide
|
C27H25N5O2
|
3
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
IC50 = 270 nM
|
|
|
| 3 |
IC50 = 2640 nM
|
|
|
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CP0433138
|
3-chloro-N-[3-[(7-chloro-1,4-dioxo-2,3-dihydrophthalazin-6-yl)amino]phenyl]benzamide
Show/Hide
|
C21H14Cl2N4O3
|
1
|
| 1 |
IC50 = 35 nM
|
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|
|
CP0533235
|
3-bromo-N-[3-[(6-chloro-1,3-dioxoisoindol-5-yl)amino]phenyl]benzamide
Show/Hide
|
C21H13BrClN3O3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0898128
|
N-(1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)phenyl)ethyl)-acetamide
Show/Hide
|
C23H21N5O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
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CP0774622
|
(R)-3-(1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)phenyl)-ethylamino)cyclohex-2-enone
Show/Hide
|
C27H25N5O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
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CP0542630
|
N-[3-[3-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C32H29F3N6O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0875477
|
N-(4-{1-[(2-Methoxyethyl)amino]ethyl}phenyl)-6-pyridin-4-ylquinazolin-2-amine
Show/Hide
|
C24H25N5O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
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CP0828631
|
(R)-5-(1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)phenyl)-ethylamino)-1,2-dihydropyridin-3(6H)-one
Show/Hide
|
C26H24N6O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0507157
|
N-[3-[3-[3-[[2-(dimethylamino)acetyl]amino]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H25F3N6O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
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CP0917067
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-tertpentylbenzamide
Show/Hide
|
C25H25N3O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
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CP0873277
|
3-Methoxy-N-(1-{4-[(6-pyridin-4-ylquinazolin-2-yl)amino]-phenyl}ethyl)propanamide
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0430673
|
N-[3-[3-[3-[2-(dimethylamino)ethyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H26F3N5O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
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CP0470155
|
N-[4-chloro-3-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H14ClF3N6O
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
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CP0460038
|
2-chloro-6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalen-1-ol
Show/Hide
|
C28H25ClN4O2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
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CP0018477
|
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H16ClF3N4O3
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
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CP0920676
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-fluoro-5-trifluoromethoxy-benzamide
Show/Hide
|
C21H13F4N3O4
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
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CP0421660
|
N-[3-[3-[3-[(dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H24F3N5O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
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CP0480155
|
N-[3-[3-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H26F3N7O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0126581
|
4-[2-(3-tert-butylanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
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CP0850040
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-Npiperidinyl-benzamide
Show/Hide
|
C25H24N4O3
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0887315
|
3-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-N-(3-(trifluoromethoxy)phenyl)benzamide
Show/Hide
|
C21H14F3N3O4
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
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CP0917373
|
4-Fluoro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13F4N3O4
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
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CP0774614
|
3-Methoxy-N-((1S)-1-{4-[(6-pyridin-4-ylquinazolin-2-yl)-amino]phenyl}ethyl)propanamide
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
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CP0666212
|
N-[2-(1-Methylpyrrolidin-2-yl)ethyl]-4-[(6-pyridin-4-ylquinazolin-2-yl)amino]benzamide
Show/Hide
|
C27H28N6O
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
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CP0507154
|
3-[7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]benzamide
Show/Hide
|
C27H18F3N5O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0874906
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-N-pyrrolylbenzamide
Show/Hide
|
C24H18N4O3
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
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CP0731363
|
N-Methyl-N-{4-[(6-pyridin-4-ylquinazolin-2-yl)amino]-phenyl}acetamide
Show/Hide
|
C22H19N5O
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
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CP0868521
|
(R)-N-(1-(4-(8-Methoxy-6-(pyridin-4-yl)quinazolin-2-ylamino)phenyl)ethyl)acetamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0846913
|
3-Fluoro-5-morpholino-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C24H21FN4O4
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0919065
|
N-(3-methoxy-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H16F3N3O5
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0476529
|
N-methyl-4-[2-[4-(trifluoromethyl)anilino]quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
|
C22H16F3N5O2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0829112
|
N-{4-[(6-Pyridin-4-ylquinazolin-2-yl)amino]phenyl}-acetamide
Show/Hide
|
C21H17N5O
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0057236
|
2-chloro-3-(2-cyanopropan-2-yloxy)-N-[5-[[2-(cyclopropanecarbonylamino)-[1,3]thiazolo[5,4-b]pyridin-5-yl]-methylamino]-2-fluorophenyl]benzamide
Show/Hide
|
C28H24ClFN6O3S
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0400769
|
N-methyl-4-[2-[3-(trifluoromethoxy)anilino]quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
|
C22H16F3N5O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0850039
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-trifluoromethoxy-5-chloro-benzamide
Show/Hide
|
C21H13ClF3N3O4
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0148135
|
N-[5-[[7-cyano-2-[[2-[2-[2-[2-[2-[2-[[7-cyano-6-[4-fluoro-3-[[2-[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]amino]-2-oxoethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetyl]amino]-1,3-benzothiazol-6-yl]oxy]-2-fluorophenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C58H46F8N8O11S2
|
2
|
| 1 |
IC50 = 73.8 nM
|
|
|
| 2 |
IC50 = 85.5 nM
|
|
|
|
CP0154430
|
N-[5-[[7-cyano-2-[[2-[2-[2-[2-[[7-cyano-6-[4-fluoro-3-[[2-[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]amino]-2-oxoethoxy]ethoxy]ethoxy]acetyl]amino]-1,3-benzothiazol-6-yl]oxy]-2-fluorophenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C54H38F8N8O9S2
|
2
|
| 1 |
IC50 = 73.9 nM
|
|
|
| 2 |
IC50 = 87.2 nM
|
|
|
|
CP0122866
|
N-(2-methoxyethyl)-4-[(6-pyridin-4-ylquinazolin-2-yl)amino]benzamide
Show/Hide
|
C23H21N5O2
|
3
|
| 1 |
IC50 = 77 nM
|
|
|
| 2 |
IC50 = 890 nM
|
|
|
| 3 |
IC50 > 30000 nM
|
|
|
|
CP0476528
|
N-methyl-4-[2-[4-(trifluoromethoxy)anilino]quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
|
C22H16F3N5O3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0156882
|
N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-4-phenylbenzenesulfonamide
Show/Hide
|
C24H18N4O3S2
|
2
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
IC50 = 220 nM
|
|
|
|
CP0838247
|
(R)-N-(1-(4-(8-Methyl-6-(pyridin-4-yl)quinazolin-2-ylamino)-phenyl)ethyl)acetamide
Show/Hide
|
C24H23N5O
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0537788
|
N-[3-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H15F3N6O
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0874907
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-5-(1-Nphenyl-3-isopropyl)-pyrazolyl-amide
Show/Hide
|
C26H23N5O3
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0045760
|
1-(3-Tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C27H26N6O3
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0725622
|
N-[2-(Dimethylamino)ethyl]-4-[(6-pyridin-4-ylquinazolin-2-yl)amino]benzamide
Show/Hide
|
C24H24N6O
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0897172
|
N-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)benzamide
Show/Hide
|
C21H13ClF3N3O3
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0474104
|
2,6-difluoro-3-[(4-methoxyphenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C21H16F2N6O3
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0762491
|
(R)-3-(1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)phenyl)-ethylamino)cyclopent-2-enone
Show/Hide
|
C26H23N5O
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0510744
|
N-[4-methoxy-3-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H17F3N6O2
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0454701
|
N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H12N4O3S3
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 260 nM
|
|
|
|
CP0576357
|
3-[(4-methoxyphenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C21H18N6O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0666213
|
6-Pyridin-4-yl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-quinazolin-2-amine
Show/Hide
|
C25H25N5O
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0838246
|
(R)-1-(2-Hydroxyethyl)-N-((R)-1-(4-(6-(pyridin-4-yl)-quinazolin-2 ylamino)phenyl)ethyl)piperidine-2-carboxamide
Show/Hide
|
C29H32N6O2
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0543117
|
N-[3-[3-(6-aminopyridin-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H17F3N6O
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0514581
|
N-[3-(3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H16F3N5O
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
|
CP0895174
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-N-pyrrolidyl-benzamide
Show/Hide
|
C24H22N4O3
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0470147
|
N-[3-[3-[2-[(dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H24F3N5O
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0393603
|
3-chloro-N-[3-[(6-chloro-1,3-dioxoisoindol-5-yl)amino]phenyl]benzamide
Show/Hide
|
C21H13Cl2N3O3
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0454703
|
N-[4-hydroxy-3-(1H-imidazol-2-ylsulfanyl)naphthalen-1-yl]thiophene-2-sulfonamide
Show/Hide
|
C17H13N3O3S3
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 170 nM
|
|
|
|
CP0666158
|
N-(2-Methoxyethyl)-2-methyl-4-[(6-pyridin-4-ylquinazolin-2-yl)amino]benzamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0919063
|
1-(3-Tert-butyl-1-(4-fluorophenyl)-1H-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C27H25FN6O3
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0887314
|
4-Chloro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H13ClF3N3O3
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0917066
|
1-(3-Tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C28H28N6O3
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0666160
|
4-[(6-Pyridin-4-ylquinazolin-2-yl)amino]-N-(2-pyrrolidin-1-ylethyl)benzamide
Show/Hide
|
C26H26N6O
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0742713
|
N-(2-Methoxyethyl)-4-{[6-(3-methylpyridin-4-yl)quinazolin-2-yl]amino}benzamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 132 nM
|
|
|
|
CP0507155
|
N-[3-[3-[4-[[2-(2-methoxyethoxy)acetyl]amino]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C31H26F3N5O4
|
1
|
| 1 |
IC50 = 139 nM
|
|
|
|
CP0435860
|
1-acetyl-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-2,3-dihydroindole-5-sulfonamide
Show/Hide
|
C22H19N5O4S2
|
2
|
| 1 |
IC50 = 140 nM
|
|
|
| 2 |
IC50 = 270 nM
|
|
|
|
CP0928815
|
N-(4-(N-(3-(1H-1,2,4-triazol-5-ylthio)-4-hydroxynaphthalen-1-yl)sulfamoyl)phenyl)acetamide
Show/Hide
|
C20H17N5O4S2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0666215
|
(R)-N-(1-(4-(7-Methoxy-6-(pyridin-4-yl)quinazolin-2-ylamino)phenyl)ethyl)acetamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0476527
|
N-methyl-4-[2-(3-propan-2-ylanilino)quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0058632
|
N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]naphthalene-2-sulfonamide
Show/Hide
|
C22H16N4O3S2
|
2
|
| 1 |
IC50 = 150 nM
|
|
|
| 2 |
IC50 = 400 nM
|
|
|
|
CP0751114
|
3-Methoxy-N-(4-(6-(pyridin-4-yl)quinazolin-2-ylamino)-phenyl)propanamide
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0440552
|
2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-phenyldiazenylbenzamide
Show/Hide
|
C20H14F2N6O2
|
1
|
| 1 |
IC50 = 157 nM
|
|
|
|
CP0751178
|
(R)-4-(1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)phenyl)-ethylamino)-5,6-dihydropyridin-2(1H)-one
Show/Hide
|
C26H24N6O
|
1
|
| 1 |
IC50 = 158 nM
|
|
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CP0472049
|
7-(3-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenyl)-N-(2-morpholinoethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
|
C27H25ClF3N7O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0691680
|
N-(2-Methoxyethyl)-N-methyl-N'-(6-pyridin-4-ylquinazolin-2-yl)benzene-1,4-diamine
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0346326
|
N-[5-[[7-cyano-2-[[2-[2-[2-[2-[2-[[7-cyano-6-[4-fluoro-3-[[2-[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]amino]-2-oxoethoxy]ethoxy]ethoxy]ethoxy]acetyl]amino]-1,3-benzothiazol-6-yl]oxy]-2-fluorophenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C56H42F8N8O10S2
|
2
|
| 1 |
IC50 = 168 nM
|
|
|
| 2 |
IC50 = 616 nM
|
|
|
|
CP0498796
|
7-(3-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenyl)-N-(2-(diethylamino)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
|
C27H27ClF3N7O2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0497201
|
4-[2-(3-bromoanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H16BrN5O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0897169
|
3-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-N-(3-(trifluoromethylthio)phenyl)benzamide
Show/Hide
|
C21H14F3N3O3S
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
|
CP0667325
|
(R)-N-(1-(4-(8-Chloro-6-(pyridin-4-yl)quinazolin-2-ylamino)-phenyl)ethyl)acetamide
Show/Hide
|
C23H20ClN5O
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
|
CP0521307
|
N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C19H13F3N4O3S2
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 210 nM
|
|
|
|
CP0566154
|
N-(4-hydroxy-3-pyridin-2-ylsulfanylnaphthalen-1-yl)thiophene-2-sulfonamide
Show/Hide
|
C19H14N2O3S3
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 350 nM
|
|
|
|
CP0920442
|
N-(3-(1H-1,2,4-triazol-5-ylthio)-4-oxonaphthalen-1(4H)-ylidene)thiophene-2-sulfonamide
Show/Hide
|
C16H10N4O3S3
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 230 nM
|
|
|
|
CP0540417
|
(1R)-1-[6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophen-3-yl]-2,2,2-trifluoroethanol
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0691699
|
N-(4-{[(2-Methoxyethyl)amino]methyl}phenyl)-6-pyridin-4-ylquinazolin-2-amine
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 = 192 nM
|
|
|
|
CP0887313
|
1-(3-Tert-butyl-phenyl)-3-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C24H24N4O3
|
1
|
| 1 |
IC50 = 195 nM
|
|
|
|
CP0731361
|
N-[4-(2-Methoxyethoxy)phenyl]-6-pyridin-4-ylquinazolin-2-amine
Show/Hide
|
C22H20N4O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0666214
|
(R)-N-((R)-1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)-phenyl)ethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H26N6O
|
1
|
| 1 |
IC50 = 214 nM
|
|
|
|
CP0470150
|
N-[3-[3-[5-[(4-ethylpiperazin-1-yl)methyl]furan-3-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C31H29F3N6O2
|
1
|
| 1 |
IC50 = 219 nM
|
|
|
|
CP0898127
|
(R)-1-methyl-N-((R)-1-(4-(6-(pyridin-4-yl)quinazolin-2-ylamino)phenyl)ethyl)piperidine-2-carboxamide
Show/Hide
|
C28H30N6O
|
1
|
| 1 |
IC50 = 223 nM
|
|
|
|
CP0471629
|
2-[4-[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C28H26N6O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0680663
|
(R)-N-(1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)phenyl)-ethyl)piperidine-4-carboxamide
Show/Hide
|
C27H28N6O
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0397031
|
ethyl 7-[3-[[4-fluoro-3-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H17F4N5O3
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0845260
|
3-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-N-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)benzamide
Show/Hide
|
C22H15F4N3O4
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0846912
|
N-(2-chloro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H13ClF3N3O4
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0400401
|
6-[2-[4-(4-methylpiperazin-1-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C29H27N7
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0506404
|
N-[4-hydroxy-3-(1-methyltetrazol-5-yl)sulfanylnaphthalen-1-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H13N5O3S3
|
2
|
| 1 |
IC50 = 250 nM
|
|
|
| 2 |
IC50 = 320 nM
|
|
|
|
CP0691681
|
(R)-N-((R)-1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)-phenyl)ethyl)piperidine-2-carboxamide
Show/Hide
|
C27H28N6O
|
1
|
| 1 |
IC50 = 254 nM
|
|
|
|
CP0762528
|
(S)-N-((R)-1-(4-(6-(Pyridin-4-yl)quinazolin-2-ylamino)-phenyl)ethyl)piperidine-3-carboxamide
Show/Hide
|
C27H28N6O
|
1
|
| 1 |
IC50 = 256 nM
|
|
|
|
CP0851561
|
N-(2-Methoxyethyl)-4-{[6-(3-methoxypyridin-4-yl)-quinazolin-2-yl]amino}benzamide
Show/Hide
|
C24H23N5O3
|
1
|
| 1 |
IC50 = 265 nM
|
|
|
|
CP0498804
|
7-(3-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenyl)-N-(3-methoxypropyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
|
C25H22ClF3N6O3
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0850037
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-5-(1-Nphenyl-3-tert-butyl)-pyrazolyl-amide
Show/Hide
|
C27H25N5O3
|
1
|
| 1 |
IC50 = 274 nM
|
|
|
|
CP0435093
|
N-(4-hydroxy-3-phenylsulfanylnaphthalen-1-yl)thiophene-2-sulfonamide
Show/Hide
|
C20H15NO3S3
|
2
|
| 1 |
IC50 = 280 nM
|
|
|
| 2 |
IC50 = 570 nM
|
|
|
|
CP0505936
|
6,7-bis(3-hydroxyanilino)-2,3-dihydrophthalazine-1,4-dione
Show/Hide
|
C20H16N4O4
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0375311
|
5-tert-butyl-N-[3-[(7-chloro-1,4-dioxo-2,3-dihydrophthalazin-6-yl)amino]phenyl]-2-methylpyrazole-3-carboxamide
Show/Hide
|
C23H23ClN6O3
|
1
|
| 1 |
IC50 = 293 nM
|
|
|
|
CP0393606
|
N-[3-[(7-chloro-1,4-dioxo-2,3-dihydrophthalazin-6-yl)amino]phenyl]-3-cyanobenzamide
Show/Hide
|
C22H14ClN5O3
|
1
|
| 1 |
IC50 = 296 nM
|
|
|
|
CP0400733
|
N-[3-[(6-chloro-1,3-dioxoisoindol-5-yl)amino]phenyl]-3-cyanobenzamide
Show/Hide
|
C22H13ClN4O3
|
1
|
| 1 |
IC50 = 297 nM
|
|
|
|
CP0532244
|
(E)-3-(4-chlorophenyl)sulfonyl-1-(4-fluorophenyl)prop-2-en-1-one
Show/Hide
|
C15H10ClFO3S
|
2
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
IC50 = 900 nM
|
|
|
|
CP0894723
|
N,N-Dimethyl-N'-{4-[(6-pyridin-4-ylquinazolin-2-yl)amino]-benzyl}ethane-1,2-diamine
Show/Hide
|
C24H26N6
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0476832
|
2,6-difluoro-3-[(2-methoxyphenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C21H16F2N6O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0480154
|
N-[3-[3-[4-(dimethylamino)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C28H22F3N5O
|
1
|
| 1 |
IC50 = 308 nM
|
|
|
|
CP0319249
|
2,6-Disubstituted Pyrazine, 79
Show/Hide
|
C25H19N5O3
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0496390
|
4-[2-(4-bromoanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H16BrN5O2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0452241
|
N-[3-[3-[2-[2-(dimethylamino)ethyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H26F3N5O
|
1
|
| 1 |
IC50 = 318 nM
|
|
|
|
CP0454702
|
N-(3-bromo-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide
Show/Hide
|
C14H10BrNO3S2
|
2
|
| 1 |
IC50 = 320 nM
|
|
|
| 2 |
IC50 = 340 nM
|
|
|
|
CP0402120
|
2,6-difluoro-3-[(2-fluorophenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C20H13F3N6O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0542633
|
N-[3-[3-(furan-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H15F3N4O2
|
1
|
| 1 |
IC50 = 326 nM
|
|
|
|
CP0758717
|
N-(2-Methoxyethyl)-3-[(6-pyridin-4-ylquinazolin-2-yl)-amino]benzamide
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0448925
|
1-[6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophen-3-yl]-2,2,2-trifluoroethanol
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0388431
|
5,6-bis(3-hydroxyanilino)isoindole-1,3-dione
Show/Hide
|
C20H15N3O4
|
1
|
| 1 |
IC50 = 338 nM
|
|
|
|
CP0852890
|
N-(4-methoxy-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H16F3N3O5
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0691692
|
2-Fluoro-N-(2-methoxyethyl)-4-[(6-pyridin-4-ylquinazolin-2-yl)amino]benzamide
Show/Hide
|
C23H20FN5O2
|
1
|
| 1 |
IC50 = 344 nM
|
|
|
|
CP0456231
|
5-tert-butyl-N-[3-[(6-chloro-1,3-dioxoisoindol-5-yl)amino]phenyl]-2-methylpyrazole-3-carboxamide
Show/Hide
|
C23H22ClN5O3
|
1
|
| 1 |
IC50 = 349 nM
|
|
|
|
CP0466242
|
N-[5-[[7-cyano-2-[[2-[2-[2-[2-[2-[2-[2-[2-[[7-cyano-6-[4-fluoro-3-[[2-[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]amino]-2-oxoethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetyl]amino]-1,3-benzothiazol-6-yl]oxy]-2-fluorophenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C62H54F8N8O13S2
|
2
|
| 1 |
IC50 = 352 nM
|
|
|
| 2 |
IC50 = 732 nM
|
|
|
|
CP0039591
|
N-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]benzamide
Show/Hide
|
C27H25N5O3
|
1
|
| 1 |
IC50 = 356 nM
|
|
|
|
CP0397032
|
ethyl 7-[3-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H17ClF3N5O3
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0534693
|
ethyl 7-[3-[[4-methyl-3-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C24H20F3N5O3
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0474105
|
2,6-difluoro-3-[(2-methoxyphenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C21H16F2N6O3
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0470149
|
N-[3-[3-[5-(pyrrolidin-1-ylmethyl)furan-3-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H24F3N5O2
|
1
|
| 1 |
IC50 = 362 nM
|
|
|
|
CP0742714
|
4-{[6-(3-Chloropyridin-4-yl)quinazolin-2-yl]amino}-N-(2-methoxyethyl)benzamide
Show/Hide
|
C23H20ClN5O2
|
1
|
| 1 |
IC50 = 369 nM
|
|
|
|
CP0521627
|
N-(3-chloro-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide
Show/Hide
|
C14H10ClNO3S2
|
2
|
| 1 |
IC50 = 380 nM
|
|
|
| 2 |
IC50 = 450 nM
|
|
|
|
CP0417157
|
4-[2-(4-methoxyanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C22H19N5O3
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0447763
|
N-[3-[3-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H26F3N7O
|
1
|
| 1 |
IC50 = 393 nM
|
|
|
|
CP0751116
|
N-(2-Methoxyethyl)-4-{[6-(2-methylpyridin-4-yl)quinazolin-2-yl]amino}benzamide
Show/Hide
|
C24H23N5O2
|
1
|
| 1 |
IC50 = 399 nM
|
|
|
|
CP0897174
|
1-(1-N-p-tolyl-3-trifluoromethyl-pyrazol-5-yl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C25H19F3N6O3
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0083690
|
4,6-dimethyl-2-(thiophene-2-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-3-one
Show/Hide
|
C13H10N2O2S2
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 600 nM
|
|
|
|
CP0521625
|
5-chloro-7-[furan-2-yl-(pyridin-2-ylamino)methyl]quinolin-8-ol
Show/Hide
|
C19H14ClN3O2
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 800 nM
|
|
|
|
CP0522719
|
2,6-Disubstituted Pyrazine, 70
Show/Hide
|
C25H24N4O5
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0536371
|
methyl 7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C22H15F3N4O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0553888
|
N-[5-[[7-cyano-2-[[2-[2-[[7-cyano-6-[4-fluoro-3-[[2-[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]amino]-2-oxoethoxy]acetyl]amino]-1,3-benzothiazol-6-yl]oxy]-2-fluorophenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C50H30F8N8O7S2
|
2
|
| 1 |
IC50 = 421 nM
|
|
|
| 2 |
IC50 = 537 nM
|
|
|
|
CP0570519
|
3-[(4-methoxyphenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C21H18N6O3
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0558572
|
2,6-difluoro-3-[(4-methoxyphenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C21H16F2N6O3
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0498799
|
ethyl 7-[3-[[4-methyl-3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C24H19F3N4O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0845254
|
3-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-N-(1-p-tolyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)benzamide
Show/Hide
|
C25H18F3N5O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0506407
|
2,3,4,5,6-pentafluoro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]benzenesulfonamide
Show/Hide
|
C18H9F5N4O3S2
|
2
|
| 1 |
IC50 = 520 nM
|
|
|
| 2 |
IC50 = 590 nM
|
|
|
|
CP0472047
|
ethyl 7-[3-[[3-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H18F3N5O3
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0476833
|
2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-[(2-methylphenyl)diazenyl]benzamide
Show/Hide
|
C21H16F2N6O2
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0470142
|
N-[3-[3-(5-morpholin-4-ylpent-1-ynyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C29H26F3N5O2
|
1
|
| 1 |
IC50 = 552 nM
|
|
|
|
CP0167610
|
2,6-Disubstituted Pyrazine, 76
Show/Hide
|
C25H24N4O5
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0448926
|
2-[4-[4-(3,4-dichlorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C24H22Cl2N4O
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0887310
|
N-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)benzamide
Show/Hide
|
C28H27N5O3
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
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CP0400772
|
N-methyl-4-[2-(4-phenoxyanilino)quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
|
C27H21N5O3
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0417156
|
4-[2-(4-fluoroanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H16FN5O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0751192
|
N-(2-Methoxyethyl)-4-[(6-pyridin-3-ylquinazolin-2-yl)-amino]benzamide
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 = 601 nM
|
|
|
|
CP0874905
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-fluoro-3-trifluoromethyl-5-chloro-benzamide
Show/Hide
|
C20H12ClF4N3O4S
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0400768
|
N-methyl-4-[2-[3-(trifluoromethyl)anilino]quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
|
C22H16F3N5O2
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0337085
|
2,6-Disubstituted Pyrazine, 77
Show/Hide
|
C25H19N5O3
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0397181
|
4-[2-(3-chloroanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H16ClN5O2
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0535232
|
2,6-difluoro-3-[(2-fluorophenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C20H13F3N6O2
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0897690
|
N-(3-(1H-1,2,4-triazol-5-ylthio)-4-hydroxynaphthalen-1-yl)-3-(2,5-dioxopyrrolidin-1-yl)-2,6-difluorobenzenesulfonamide
Show/Hide
|
C22H15F2N5O5S2
|
2
|
| 1 |
IC50 = 670 nM
|
|
|
| 2 |
IC50 = 680 nM
|
|
|
|
CP0887308
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-trifluoromethyl-5-chloro-benzamide
Show/Hide
|
C20H13ClF3N3O4S
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0521626
|
7-[(3-bromo-4-hydroxy-5-methoxyphenyl)-(pyridin-2-ylamino)methyl]-5-chloroquinolin-8-ol
Show/Hide
|
C22H17BrClN3O3
|
2
|
| 1 |
IC50 = 700 nM
|
|
|
| 2 |
IC50 = 3000 nM
|
|
|
|
CP0506405
|
N-[4-hydroxy-3-(2H-triazol-4-ylsulfanyl)naphthalen-1-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H12N4O3S3
|
2
|
| 1 |
IC50 = 720 nM
|
|
|
| 2 |
IC50 = 1470 nM
|
|
|
|
CP0506406
|
N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]octane-1-sulfonamide
Show/Hide
|
C20H26N4O3S2
|
2
|
| 1 |
IC50 = 720 nM
|
|
|
| 2 |
IC50 = 1660 nM
|
|
|
|
CP0887305
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-4-(trifluoromethyl)benzamide
Show/Hide
|
C20H14F3N3O4S
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0887306
|
1-(2-N-morpholyl-5-(trifluoromethyl)phenyl)-3-(3-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C25H22F3N5O4
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0895175
|
N-(2,4-dichloro-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C21H12Cl2F3N3O4
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0742715
|
N-(2-Methoxyethyl)-4-(6-(pyrimidin-5-yl)quinazolin-2-ylamino)benzamide
Show/Hide
|
C22H20N6O2
|
1
|
| 1 |
IC50 = 777 nM
|
|
|
|
CP0433850
|
7-[(pyridin-3-ylamino)-thiophen-3-ylmethyl]quinolin-8-ol
Show/Hide
|
C19H15N3OS
|
2
|
| 1 |
IC50 = 800 nM
|
|
|
| 2 |
IC50 = 2000 nM
|
|
|
|
CP0421659
|
N-[3-[3-[5-(4-methylpiperazin-1-yl)pent-1-ynyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C30H29F3N6O
|
1
|
| 1 |
IC50 = 842 nM
|
|
|
|
CP0897178
|
N-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)benzenesulfonamide
Show/Hide
|
C19H15N3O4S
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0433851
|
7-[(4-methoxyphenyl)-morpholin-4-ylmethyl]quinolin-8-ol
Show/Hide
|
C21H22N2O3
|
2
|
| 1 |
IC50 = 900 nM
|
|
|
| 2 |
IC50 = 4000 nM
|
|
|
|
CP0680658
|
N-(2-Methoxyethyl)-4-(6-phenylquinazolin-2-ylamino)-benzamide
Show/Hide
|
C24H22N4O2
|
1
|
| 1 |
IC50 = 917 nM
|
|
|
|
CP0845257
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1-naphtoylamide
Show/Hide
|
C24H17N3O3
|
1
|
| 1 |
IC50 = 920 nM
|
|
|
|
CP0438923
|
N-[3-[3-(2-morpholin-4-ylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C28H22F3N7O2
|
1
|
| 1 |
IC50 = 941 nM
|
|
|
|
CP0897177
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-thiomorpholinoisonicotinamide
Show/Hide
|
C23H21N5O3S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0472048
|
ethyl 7-[3-[[4-methoxy-3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C24H19F3N4O4
|
1
|
| 1 |
IC50 = 1030 nM
|
|
|
|
CP0540595
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]isoquinolin-1-amine
Show/Hide
|
C27H26N6O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0337084
|
2,6-Disubstituted Pyrazine, 13
Show/Hide
|
C20H20N4O4
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0848912
|
1-(3,4-Difluorophenyl)-3-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C20H14F2N4O3
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0124123
|
1-phenyl-3-(4-{6-[(3,4,5-trimethoxyphenyl)amino]pyrazin-2-yl}phenyl)urea
Show/Hide
|
C26H25N5O4
|
1
|
| 1 |
IC50 = 1160 nM
|
|
|
|
CP0515851
|
2,6-Disubstituted Pyrazine, 26
Show/Hide
|
C23H21N3O4
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0384790
|
N,N-dimethyl-2-[4-[4-[4-(4-methyl-1H-pyrazol-5-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
|
C28H28N6O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0503030
|
4-[2-(4-bromoanilino)quinazolin-6-yl]oxy-N-(2-piperidin-1-ylethyl)pyridine-2-carboxamide
Show/Hide
|
C27H27BrN6O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0504128
|
4-[2-(2-ethylanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0375833
|
6-(2-piperidin-4-yl-5-pyridin-4-yl-1H-imidazol-4-yl)-1,4-dihydroindeno[1,2-c]pyrazole
Show/Hide
|
C23H22N6
|
1
|
| 1 |
IC50 = 1330 nM
|
|
|
|
CP0908288
|
2-(3,4,5-Trimethoxyphenylamino)-6-(indanone-oxime-4-oxy)-pyrazine
Show/Hide
|
C22H22N4O5
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0540598
|
7-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalen-2-ol
Show/Hide
|
C28H26N4O2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0496541
|
2,2,2-trifluoroethyl 7-(3-(3-(trifluoromethyl)benzamido)phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H14F6N4O3
|
1
|
| 1 |
IC50 = 1450 nM
|
|
|
|
CP0525917
|
2,6-Disubstituted Pyrazine, 53
Show/Hide
|
C22H20N4O4
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0086818
|
ethyl 7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H17F3N4O3
|
2
|
| 1 |
IC50 = 1500 nM
|
|
|
| 2 |
IC50 = 1540 nM
|
|
|
|
CP0874904
|
3-Bromo-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C20H14BrN3O3
|
1
|
| 1 |
IC50 = 1560 nM
|
|
|
|
CP0492256
|
ethyl 7-[3-[[3-(trifluoromethoxy)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H17F3N4O4
|
1
|
| 1 |
IC50 = 1570 nM
|
|
|
|
CP0479283
|
N,N-dimethyl-2-[4-[4-[4-(1H-pyrazol-5-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
|
C27H26N6O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0433852
|
N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]decane-1-sulfonamide
Show/Hide
|
C22H30N4O3S2
|
2
|
| 1 |
IC50 = 1600 nM
|
|
|
| 2 |
IC50 = 2100 nM
|
|
|
|
CP0846164
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzenesulfonamide
Show/Hide
|
C19H15N3O4S
|
1
|
| 1 |
IC50 = 1660 nM
|
|
|
|
CP0525084
|
5-anilino-6-(3-hydroxyanilino)isoindole-1,3-dione
Show/Hide
|
C20H15N3O3
|
1
|
| 1 |
IC50 = 1680 nM
|
|
|
|
CP0459592
|
2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-phenyldiazenylbenzamide
Show/Hide
|
C20H14F2N6O2
|
1
|
| 1 |
IC50 = 1680 nM
|
|
|
|
CP0427114
|
2,6-difluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-[(2-methylphenyl)diazenyl]benzamide
Show/Hide
|
C21H16F2N6O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0407701
|
2-[4-[4-(1H-benzo[g]indazol-7-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C29H26N6O
|
1
|
| 1 |
IC50 = 1710 nM
|
|
|
|
CP0006184
|
6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione
Show/Hide
|
C14H6O8
|
1
|
| 1 |
IC50 = 1760 nM
|
|
|
|
CP0402327
|
2-[4-[4-(4,5-dihydro-1H-benzo[g]indazol-7-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C29H28N6O
|
1
|
| 1 |
IC50 = 1840 nM
|
|
|
|
CP0402329
|
[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]-morpholin-4-ylmethanone
Show/Hide
|
C24H20N4O3
|
1
|
| 1 |
IC50 = 2150 nM
|
|
|
|
CP0400767
|
4-(2-anilinoquinazolin-6-yl)oxy-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H17N5O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0828632
|
(R)-N-(1-(4-(7-Chloro-6-(pyridin-4-yl)quinazolin-2-ylamino)-phenyl)ethyl)acetamide
Show/Hide
|
C23H20ClN5O
|
1
|
| 1 |
IC50 = 2290 nM
|
|
|
|
CP0828633
|
N-(2-Methoxyethyl)-4-{[6-(6-methoxypyridin-3-yl)-quinazolin-2-yl]amino}benzamide
Show/Hide
|
C24H23N5O3
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0419311
|
2,6-Disubstituted Pyrazine, 78
Show/Hide
|
C24H18N4O4
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0691706
|
(R)-N-(1-(4-(7-Methyl-6-(pyridin-4-yl)quinazolin-2-ylamino)-phenyl)ethyl)acetamide
Show/Hide
|
C24H23N5O
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0518649
|
2,6-difluoro-3-[(4-fluorophenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
|
C20H13F3N6O2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0902250
|
1-(3-Fluorophenyl)-3-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)urea
Show/Hide
|
C20H15FN4O3
|
1
|
| 1 |
IC50 = 2750 nM
|
|
|
|
CP0398708
|
[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]-piperazin-1-ylmethanone
Show/Hide
|
C24H21N5O2
|
1
|
| 1 |
IC50 = 2780 nM
|
|
|
|
CP0491871
|
2,6-Disubstituted Pyrazine, 4
Show/Hide
|
C18H18N4O3
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0515845
|
2,6-Disubstituted Pyrazine, 10
Show/Hide
|
C20H19N3O4
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0375308
|
3-(3-hydroxyphenyl)-1H-pyrrolo[3,4-f]indole-5,7-dione
Show/Hide
|
C16H10N2O3
|
1
|
| 1 |
IC50 = 3470 nM
|
|
|
|
CP0205431
|
2,6-Disubstituted Pyrazine, 1
Show/Hide
|
C21H22N4O4
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0498798
|
ethyl 7-[3-[[4-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H18F3N5O3
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0398601
|
[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]methanone
Show/Hide
|
C28H30N6O2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0521308
|
3-(dibenzylamino)-2,6-difluoro-N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-yl]benzenesulfonamide
Show/Hide
|
C32H25F2N5O3S2
|
2
|
| 1 |
IC50 = 3600 nM
|
|
|
| 2 |
IC50 = 5800 nM
|
|
|
|
CP0405630
|
2-[4-[4-[4-(4-chloro-1H-pyrazol-5-yl)phenyl]-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C27H25ClN6O
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0533234
|
6-anilino-7-(3-hydroxyanilino)-2,3-dihydrophthalazine-1,4-dione
Show/Hide
|
C20H16N4O3
|
1
|
| 1 |
IC50 = 3770 nM
|
|
|
|
CP0531924
|
2,6-Disubstituted Pyrazine, 56
Show/Hide
|
C22H20N4O4
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0439815
|
2,6-Disubstituted Pyrazine, 6
Show/Hide
|
C19H19N3O4
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0534695
|
ethyl 7-[3-[[4-chloro-3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H16ClF3N4O3
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1
|
| 1 |
IC50 = 4270 nM
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CP0481390
|
2,6-Disubstituted Pyrazine, 21
Show/Hide
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C18H19N5O3
|
1
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| 1 |
IC50 = 4700 nM
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CP0848902
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N-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)benzamide
Show/Hide
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C21H13F4N3O3
|
1
|
| 1 |
IC50 = 4700 nM
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CP0491872
|
2,6-Disubstituted Pyrazine, 23
Show/Hide
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C19H20N4O4
|
1
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| 1 |
IC50 = 4900 nM
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CP0400771
|
N-methyl-4-[2-(2-phenoxyanilino)quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
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C27H21N5O3
|
1
|
| 1 |
IC50 = 5300 nM
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CP0691684
|
4-{[6-(6-Fluoropyridin-3-yl)quinazolin-2-yl]amino}-N-(2-methoxyethyl)benzamide
Show/Hide
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C23H20FN5O2
|
1
|
| 1 |
IC50 = 5400 nM
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CP0491878
|
2,6-Disubstituted Pyrazine, 67
Show/Hide
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C21H22N4O5
|
1
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| 1 |
IC50 = 5500 nM
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CP0398387
|
N-[2-(dimethylamino)ethyl]-7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
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C25H23F3N6O2
|
1
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| 1 |
IC50 = 5880 nM
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CP0488695
|
MLS001221393
Show/Hide
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C14H11NO3S2
|
2
|
| 1 |
IC50 = 6100 nM
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| 2 |
IC50 = 9000 nM
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CP0492254
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N-(2-morpholin-4-ylethyl)-7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
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C27H25F3N6O3
|
1
|
| 1 |
IC50 = 6340 nM
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CP0846163
|
4-Chloro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethyl)benzenesulfonamide
Show/Hide
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C20H13ClF3N3O4S
|
1
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| 1 |
IC50 = 6800 nM
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CP0472046
|
2-(dimethylamino)ethyl 7-(3-(3-(trifluoromethyl)benzamido)phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
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C25H22F3N5O3
|
1
|
| 1 |
IC50 = 7070 nM
|
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CP0531911
|
2,6-Disubstituted Pyrazine, 32
Show/Hide
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C21H20N4O4
|
1
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| 1 |
IC50 = 7400 nM
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CP0381257
|
[4-(1,4-dihydroindeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
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C25H23N5O2
|
1
|
| 1 |
IC50 = 7500 nM
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CP0535233
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2,6-difluoro-3-[(4-fluorophenyl)diazenyl]-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide
Show/Hide
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C20H13F3N6O2
|
1
|
| 1 |
IC50 = 8100 nM
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CP0400770
|
4-[2-(4-bromoanilino)quinazolin-6-yl]oxy-N-(2-hydroxyethyl)pyridine-2-carboxamide
Show/Hide
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C22H18BrN5O3
|
1
|
| 1 |
IC50 = 8600 nM
|
|
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CP0488105
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalen-2-ol
Show/Hide
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C28H26N4O2
|
1
|
| 1 |
IC50 = 8800 nM
|
|
|
|
CP0488107
|
N,N-dimethyl-2-[4-[4-(3-propylsulfanyl-1-benzothiophen-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
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C29H30N4OS2
|
1
|
| 1 |
IC50 = 9400 nM
|
|
|
|
CP0501819
|
2,6-Disubstituted Pyrazine, 30
Show/Hide
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C23H21N3O3S
|
1
|
| 1 |
IC50 = 9800 nM
|
|
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CP0524318
|
2,6-Disubstituted Pyrazine, 12
Show/Hide
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C20H18N4O3
|
1
|
| 1 |
IC50 = 9800 nM
|
|
|
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CP0515405
|
2,6-Disubstituted Pyrazine, 54
Show/Hide
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C22H20N4O4
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
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CP0524319
|
2,6-Disubstituted Pyrazine, 62
Show/Hide
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C25H23N3O4
|
1
|
| 1 |
IC50 = 10000 nM
|
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CP0429583
|
ethyl 7-[3-[[4-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
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C23H17F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0454251
|
ethyl 7-[3-[[2-methyl-5-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
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C24H19F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0457500
|
ethyl 7-[3-[(3-chlorobenzoyl)amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
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C22H17ClN4O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0492255
|
N-methyl-7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
|
C22H16F3N5O2
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0496353
|
N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
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C21H12F3N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0496354
|
N-(3-pyrazolo[1,5-a]pyrimidin-7-ylphenyl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C20H13F3N4O
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0496355
|
ethyl 7-[3-[(3-cyanobenzoyl)amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
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C23H17N5O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0498797
|
7-(3-(3-(trifluoromethyl)benzamido)phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
Show/Hide
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C21H14F3N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0498800
|
ethyl 7-[3-[(3-bromobenzoyl)amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C22H17BrN4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0498802
|
ethyl 7-(3-benzamidophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C22H18N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0510082
|
ethyl 7-[3-[[2-chloro-5-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H16ClF3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0510083
|
ethyl 7-[3-[(3-methoxybenzoyl)amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H20N4O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0510084
|
ethyl 7-[3-[(3-methylbenzoyl)amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H20N4O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0534691
|
7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
Show/Hide
|
C21H13F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0534692
|
ethyl 7-[3-[[2-chloro-5-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H17ClF3N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0534694
|
ethyl 7-[3-[[2-(trifluoromethyl)phenyl]carbamoylamino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C23H18F3N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0536372
|
ethyl 7-[3-[(3-chlorophenyl)carbamoylamino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
Show/Hide
|
C22H18ClN5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0452240
|
N-[3-[3-[4-(dimethylsulfamoyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C28H22F3N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0845255
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-(3-trifluoromethylphenyl)acetamide
Show/Hide
|
C21H16F3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0859606
|
N-(2-methyl-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H16F3N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0887311
|
N-(4-methyl-3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H16F3N3O4
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0897167
|
3-(1H-imidazol-1-yl)-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C23H17N5O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0917374
|
7-(3-(3-(Trifluoromethoxy)benzylamino)phenoxy)-1H-imidazo[4,5-b]pyridin-2(3H)-one
Show/Hide
|
C21H15F3N2O3
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0924127
|
N-(2-methyl-5-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
Show/Hide
|
C22H16F3N3O4
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0924128
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-(3-trifluoromethoxyphenyl)acetamide
Show/Hide
|
C21H16F3N3O5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
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CP0372502
|
[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-[4-(1-methyl-4H-indeno[1,2-c]pyrazol-6-yl)-5-pyridin-4-ylfuran-2-yl]methanone
Show/Hide
|
C29H32N6O2
|
1
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| 1 |
IC50 > 10000 nM
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|
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|
CP0384792
|
7-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2,4,4a,5-tetrahydroindeno[1,2-c]pyridazin-3-one
Show/Hide
|
C29H28N6O2
|
1
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| 1 |
IC50 > 10000 nM
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|
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|
CP0407702
|
2-[4-[4-(2,4-dihydroindeno[1,2-d]triazol-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C27H25N7O
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0545374
|
5-[4-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]phenyl]-1H-pyrazole-4-carbonitrile
Show/Hide
|
C28H25N7O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0525083
|
3-(3-hydroxyphenyl)-1H-indole-5-carboxamide
Show/Hide
|
C15H12N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
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CP0446938
|
1-[5-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophen-2-yl]-2,2,2-trifluoroethanol
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0446939
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2H-isoquinolin-1-one
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0448933
|
1-[6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophen-3-yl]-2,2,3,3,3-pentafluoropropan-1-ol
Show/Hide
|
C29H25F5N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0449276
|
N,N-dimethyl-2-[4-[4-(3-propylsulfinyl-1-benzothiophen-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
|
C29H30N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
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|
CP0450512
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophene-3-carbaldehyde
Show/Hide
|
C27H24N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0472518
|
1-[6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophen-3-yl]propan-1-ol
Show/Hide
|
C29H30N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0481260
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzofuran-3-carboxamide
Show/Hide
|
C27H25N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0488106
|
[6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzothiophen-3-yl]methanol
Show/Hide
|
C27H26N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0511241
|
2-[4-[4-(6-fluoronaphthalen-2-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C28H25FN4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0517620
|
1-[4-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]phenyl]-2,2,2-trifluoroethanol
Show/Hide
|
C26H25F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0520356
|
[6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1-benzofuran-3-yl]methanol
Show/Hide
|
C27H26N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0540413
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]naphthalene-2-carboxylic acid
Show/Hide
|
C29H26N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0540599
|
N,N-dimethyl-2-[4-[4-(3-methylsulfinyl-1-benzothiophen-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
|
C27H26N4O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0540600
|
2-[4-[4-(3-chloro-4-fluorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]-N,N-dimethylethanamine
Show/Hide
|
C24H22ClFN4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0914322
|
2-(3,4,5-Trimethoxyphenylamino)-6-(3-hydroxyiminoeth-2-ylphenoxy)-pyrazine
Show/Hide
|
C21H22N4O5
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0852889
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C20H14F3N3O5S
|
1
|
| 1 |
IC50 = 11300 nM
|
|
|
|
CP0506608
|
2,6-Disubstituted Pyrazine, 24
Show/Hide
|
C19H19FN4O3
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0522717
|
2,6-Disubstituted Pyrazine, 66
Show/Hide
|
C21H22N4O5
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0419310
|
2,6-Disubstituted Pyrazine, 9
Show/Hide
|
C22H23N3O5
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0515404
|
2,6-Disubstituted Pyrazine, 22
Show/Hide
|
C21H23N5O4
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
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CP0897176
|
4-bromo-N-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)benzamide
Show/Hide
|
C20H14BrN3O3
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0511261
|
N,N-dimethyl-2-[4-[4-(3-methylsulfanyl-1-benzothiophen-6-yl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenoxy]ethanamine
Show/Hide
|
C27H26N4OS2
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0846911
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C20H14F3N3O4S
|
1
|
| 1 |
IC50 = 15400 nM
|
|
|
|
CP0917375
|
4-chloro-N-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H13ClF3N3O3
|
1
|
| 1 |
IC50 = 15900 nM
|
|
|
|
CP0481391
|
2,6-Disubstituted Pyrazine, 20
Show/Hide
|
C19H20N4O3
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0491875
|
2,6-Disubstituted Pyrazine, 28
Show/Hide
|
C18H18N4O4
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0506607
|
2,6-Disubstituted Pyrazine, 19
Show/Hide
|
C21H23N5O4
|
1
|
| 1 |
IC50 = 16000 nM
|
|
|
|
CP0481392
|
2,6-Disubstituted Pyrazine, 59
Show/Hide
|
C22H21N3O5
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
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CP0531912
|
2,6-Disubstituted Pyrazine, 31
Show/Hide
|
C23H25N3O4
|
1
|
| 1 |
IC50 = 18000 nM
|
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CP0531922
|
2,6-Disubstituted Pyrazine, 7
Show/Hide
|
C19H19N3O4
|
1
|
| 1 |
IC50 = 18000 nM
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|
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|
CP0510235
|
1-[3-({6-[(3,4,5-trimethoxyphenyl)amino]pyrazin-2-yl}oxy)phenyl]ethan-1-one
Show/Hide
|
C21H21N3O5
|
1
|
| 1 |
IC50 = 19000 nM
|
|
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CP0515846
|
2,6-Disubstituted Pyrazine, 25
Show/Hide
|
C19H19FN4O3
|
1
|
| 1 |
IC50 = 19000 nM
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|
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CP0491879
|
2,6-Disubstituted Pyrazine, 61
Show/Hide
|
C22H21N3O5
|
1
|
| 1 |
IC50 = 22000 nM
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CP0515842
|
2,6-Disubstituted Pyrazine, 5
Show/Hide
|
C18H18N4O3
|
1
|
| 1 |
IC50 = 22000 nM
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CP0887312
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzo[b]thiophene-5-carboxamide
Show/Hide
|
C22H15N3O3S
|
1
|
| 1 |
IC50 = 22000 nM
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CP0399192
|
4-[2-(2-bromoanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
Show/Hide
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C21H16BrN5O2
|
1
|
| 1 |
IC50 = 24000 nM
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|
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CP0887309
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)naphthalene-1-sulfonamide
Show/Hide
|
C23H17N3O4S
|
1
|
| 1 |
IC50 = 25000 nM
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|
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CP0399191
|
N-methyl-4-[2-(4-pyridin-3-ylanilino)quinazolin-6-yl]oxypyridine-2-carboxamide
Show/Hide
|
C26H20N6O2
|
1
|
| 1 |
IC50 = 25000 nM
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|
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CP0846910
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C20H15N3O3
|
1
|
| 1 |
IC50 = 25200 nM
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|
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CP0431610
|
N-(3-{5-[(3,4,5-trimethoxyphenyl)amino]pyridin-3-yl}phenyl)acetamide
Show/Hide
|
C22H23N3O4
|
1
|
| 1 |
IC50 = 26000 nM
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|
|
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CP0515551
|
(4-{6-[(3,4,5-trimethoxyphenyl)amino]pyrazin-2-yl}phenyl)methanol
Show/Hide
|
C20H21N3O4
|
1
|
| 1 |
IC50 = 26000 nM
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|
|
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CP0920524
|
2-(3,4,5-Trimethoxyphenylamino)-6-(4-hydroxyiminoeth-2-ylphenoxy)-pyrazine
Show/Hide
|
C21H22N4O5
|
1
|
| 1 |
IC50 = 26000 nM
|
|
|
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CP0515848
|
2,6-Disubstituted Pyrazine, 55
Show/Hide
|
C22H20N4O4
|
1
|
| 1 |
IC50 = 29000 nM
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|
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|
CP0531923
|
2,6-Disubstituted Pyrazine, 57
Show/Hide
|
C23H23N3O5
|
1
|
| 1 |
IC50 = 29000 nM
|
|
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CP0515850
|
2,6-Disubstituted Pyrazine, 27
Show/Hide
|
C19H19N3O4
|
1
|
| 1 |
IC50 = 31000 nM
|
|
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CP0481394
|
1-[4-({6-[(3,4,5-trimethoxyphenyl)amino]pyrazin-2-yl}oxy)phenyl]ethan-1-one
Show/Hide
|
C21H21N3O5
|
1
|
| 1 |
IC50 = 34000 nM
|
|
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CP0009041
|
5-propan-2-yl-7,8-dihydro-6H-indeno[1,2-b]indole-9,10-dione
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 > 35000 nM
|
|
|
|
CP0515406
|
2,6-Disubstituted Pyrazine, 65
Show/Hide
|
C19H18ClN3O4
|
1
|
| 1 |
IC50 = 36000 nM
|
|
|
|
CP0525918
|
2,6-Disubstituted Pyrazine, 52
Show/Hide
|
C22H21N3O6
|
1
|
| 1 |
IC50 = 44000 nM
|
|
|
|
CP0515849
|
2,6-Disubstituted Pyrazine, 29
Show/Hide
|
C18H18N4O4
|
1
|
| 1 |
IC50 = 45000 nM
|
|
|
|
CP0515852
|
2,6-Disubstituted Pyrazine, 63
Show/Hide
|
C19H18FN3O4
|
1
|
| 1 |
IC50 = 45000 nM
|
|
|
|
CP0515552
|
2,6-Disubstituted Pyrazine, 64
Show/Hide
|
C19H18FN3O4
|
1
|
| 1 |
IC50 = 56000 nM
|
|
|
|
CP0845256
|
4-Chloro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzamide
Show/Hide
|
C19H14ClN3O4S
|
1
|
| 1 |
IC50 = 68000 nM
|
|
|
|
CP0522718
|
2,6-Disubstituted Pyrazine, 60
Show/Hide
|
C22H21N3O5
|
1
|
| 1 |
IC50 = 70000 nM
|
|
|
|
CP0491873
|
2,6-Disubstituted Pyrazine, 58
Show/Hide
|
C23H23N3O5
|
1
|
| 1 |
IC50 = 76000 nM
|
|
|
|
CP0850035
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-trifluoromethoxy-benzamide
Show/Hide
|
C21H14F3N3O4
|
1
|
| 1 |
IC50 = 79000 nM
|
|
|
|
CP0935594
|
2-(3,4,5-Trimethoxyphenylamino)-6-(tetralonyl-1-oxime-5-oxy)-pyrazine
Show/Hide
|
C22H22N4O5
|
1
|
| 1 |
IC50 = 86000 nM
|
|
|
|
CP0924129
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-2-phenylacetamide
Show/Hide
|
C20H17N3O4S
|
1
|
| 1 |
IC50 = 87000 nM
|
|
|
|
CP0938802
|
2-(3,4,5-Trimethoxyphenylamino)-6-(tetralonyl-1-oxime-6-oxy)-pyrazine
Show/Hide
|
C23H24N4O5
|
1
|
| 1 |
IC50 = 92000 nM
|
|
|
|
CP0897166
|
2-Chloro-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)isonicotinamide
Show/Hide
|
C19H13ClN4O3
|
1
|
| 1 |
IC50 = 93000 nM
|
|
|
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CP0897168
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-phenylpropanamide
Show/Hide
|
C21H19N3O4S
|
1
|
| 1 |
IC50 = 94000 nM
|
|
|
|
CP0439816
|
Acetamidopyrazine, 16
Show/Hide
|
C23H25N5O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0481393
|
2,6-Disubstituted Pyrazine, 26a
Show/Hide
|
C23H21N3O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0846909
|
N-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)-3-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C20H14F3N3O4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0848901
|
1,3-Dimethyl-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0848905
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-6-(3,4-dihydro-2H-benzo[b][1,4]-dioxepinoyl)amide
Show/Hide
|
C23H19N3O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0848906
|
3-fluoro-5-morpholino-N-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)benzamide
Show/Hide
|
C24H21FN4O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0848908
|
N-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)benzamide
Show/Hide
|
C20H15N3O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0852888
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-3-dimethylamino-benzamide
Show/Hide
|
C21H20N4O4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0866912
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-5-(2,3-dihydrobenzo[b]1,4-dioxinoyl)amide
Show/Hide
|
C22H17N3O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0874278
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1-phenyl-1Hpyrazole-5-carboxamide
Show/Hide
|
C23H17N5O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0887304
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)benzo[c][1,2,5]thiadiazole-5-carboxamide
Show/Hide
|
C20H15N5O3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0887307
|
N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C24H16F3N5O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0887316
|
1-Benzyl-3-tert-butyl-N-(3-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)-1H-pyrazole-5-carboxamide
Show/Hide
|
C28H27N5O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0897175
|
N-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C20H14F3N3O5S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0943552
|
4-chloro-N-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yloxy)phenyl)-3-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C20H13ClF3N3O4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0450515
|
7-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1H-quinolin-2-one
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0540596
|
6-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-1H-quinolin-2-one
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0663176
|
N-[2,4-Difluoro-3-(5H-pyrrolo[2,3-b]pyrazine-7-carbonyl)-phenyl]-4-trifluoromethyl-benzenesulfonamide
Show/Hide
|
C20H11F5N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0691085
|
Propane-1-sulfonic acid [3-(2-bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbonyl)-2,4-difluorophenyl]amide
Show/Hide
|
C16H13BrF2N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0691087
|
Propane-1-sulfonic acid [2,4-difluoro-3-(5H-pyrrolo[2,3-b]pyrazine-7-carbonyl)-phenyl]amide
Show/Hide
|
C16H14F2N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0755081
|
N-[2-Fluoro-3-(5H-pyrrolo [2,3-b]pyrazine-7-carbonyl)-phenyl]-4-trifluoromethyl-benzenesulfonamide
Show/Hide
|
C20H12F4N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0859920
|
Propane-1-sulfonic acid (2,4-difluoro-3-[2-(2-methoxypyrimidin-5-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carbonyl]phenyl)amide
Show/Hide
|
C21H18F2N6O4S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0659300
|
N-[2,4-Difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-2,4-difluoro-benzenesulfonamide
Show/Hide
|
C19H10F4N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0659301
|
N-[2,4-Difluoro-3-(4-methoxy-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-4-trifluoromethyl-benzenesulfonamide
Show/Hide
|
C21H13F5N4O4S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0660126
|
2,4-Difluoro-N-[2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
|
C19H11F3N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0660127
|
Ethanesulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C15H12F2N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0660131
|
N-[2,4-Difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-4-propyl-benzenesulfonamide
Show/Hide
|
C22H18F2N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0674366
|
Dimethylamine-1-sulfonic acid [3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-2,4-difluoro-phenyl]-amide
Show/Hide
|
C15H13F2N5O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0674367
|
N-[2-Fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-4-trifluoromethyl-benzenesulfonamide
Show/Hide
|
C20H12F4N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0674368
|
propane-1-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C16H14F2N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0678550
|
propane-1-sulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C16H15FN4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0684011
|
2,5-Difluoro-N-[2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
|
C19H11F3N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0684012
|
Propane-1-sulfonic acid [2,4-difluoro-3-(4-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C17H16F2N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0684452
|
Propane-1-sulfonic acid [2-fluoro-3-(4-methoxy-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C17H17FN4O4S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0684454
|
Cyclohexanesulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C19H18F2N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0684456
|
N-[2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-4-trifluoromethyl-benzenesulfonamide
Show/Hide
|
C20H11F5N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0689045
|
Pyridine-3-sulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C18H12FN5O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0689047
|
N-[2,4-Difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-4-isopropyl-benzenesulfonamide
Show/Hide
|
C22H18F2N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0694125
|
Cyclohexanesulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C19H19FN4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0697822
|
2,6-Difluoro-N-[2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
|
C19H11F3N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0739554
|
N-[2,4-Difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-2,5-difluoro-benzenesulfonamide
Show/Hide
|
C19H10F4N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0739555
|
Pyridine-3-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C19H13F2N5O4S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0739636
|
2,2,2-Trifluoro-ethanesulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C15H9F5N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0745935
|
Cyclopentanesulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C18H17FN4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0745936
|
Cyclobutanesulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C17H15FN4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0745937
|
N-[2,4-Difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-3-fluoro-benzenesulfonamide
Show/Hide
|
C19H11F3N4O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0745938
|
Pyridine-2-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
|
C18H11F2N5O3S
|
1
|
| 1 |
IC50 <= 10000 nM
|
|
|
|
CP0747766
|
N-[2,4-Difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-2,6-difluoro-benzenesulfonamide
Show/Hide
|
C19H10F4N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0819609
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Butane-2-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H16F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0819612
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Cyclopentanesulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C18H16F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0819613
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3-Fluoro-N-[2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
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C19H12F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0819614
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2,2,2-Trifluoro-ethanesulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
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C15H10F4N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0819615
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4-Difluoromethoxy-N-[2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
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C20H12F4N4O4S
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1
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| 1 |
IC50 <= 10000 nM
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CP0819783
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N-[2,4-Difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-2-fluoro-benzenesulfonamide
Show/Hide
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C19H11F3N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0833627
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Pyrrolidine-1-sulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H16FN5O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0840298
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Pentane-2-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C18H18F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0840299
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2-Methyl-propane-1-sulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H17FN4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0843597
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Propane-1-sulfonic acid [2,4-difluoro-3-(4-methoxy-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H16F2N4O4S
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1
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| 1 |
IC50 <= 10000 nM
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CP0843600
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3,3,3-Trifluoro-propane-1-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C16H11F5N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0843601
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4-tert-Butyl-N-[2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
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C23H20F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0859835
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Morpholine-4-sulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H16FN5O4S
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1
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| 1 |
IC50 <= 10000 nM
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CP0859836
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Propane-2-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C16H14F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0865033
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N-[2-Fluoro-3-(4-methoxy-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-4-trifluoromethyl-benzenesulfonamide
Show/Hide
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C21H14F4N4O4S
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1
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| 1 |
IC50 <= 10000 nM
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CP0880924
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Pyrrolidine-1-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H15F2N5O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0880960
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3-Difluoromethoxy-N-[2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
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C20H12F4N4O4S
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1
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| 1 |
IC50 <= 10000 nM
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CP0896546
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Cyclobutanesulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H14F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0935547
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2-Fluoro-N-[2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
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C19H12F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0940828
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2-Methyl-propane-1-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H16F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0953064
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Morpholine-4-sulfonic acid [2,4-difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H15F2N5O4S
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1
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| 1 |
IC50 <= 10000 nM
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CP0953983
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Butane-2-sulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C17H17FN4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0954254
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N-[2,4-Difluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-4-fluoro-benzenesulfonamide
Show/Hide
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C19H11F3N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0958506
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N,N-Dimethylamino-sulfonic acid [2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-amide
Show/Hide
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C15H14FN5O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0967547
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4-Fluoro-N-[2-fluoro-3-(7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-benzenesulfonamide
Show/Hide
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C19H12F2N4O3S
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1
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| 1 |
IC50 <= 10000 nM
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CP0026977
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SB-590885
Show/Hide
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C27H27N5O2
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1
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| 1 |
Kd = 0.16 nM
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