Brief Information of the Compound and Protein
Compound Name
4,6-dimethyl-2-(thiophene-2-carbonyl)-[1,2]thiazolo[5,4-b]pyridin-3-one
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PubChem ID
CID: 2816786
Canonical SMILES
Cc1cc(C)c2c(n1)sn(C(=O)c1cccs1)c2=O
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Compound Formula C13H10N2O2S2
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
2
IC50 = 600 nM
   TI
   LI
   LO
   TS