Brief Information of the Compound and Protein
Compound Name
N-[5-[[7-cyano-2-[[2-(2-methoxyethoxy)acetyl]amino]-1,3-benzothiazol-6-yl]oxy]-2-fluorophenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
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PubChem ID
CID: 145982961
Canonical SMILES
COCCOCC(=O)Nc1nc2ccc(Oc3ccc(F)c(NC(=O)Cc4cccc(c4)C(F)(F)F)c3)c(C#N)c2s1
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Compound Formula C28H22F4N4O5S
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 5.75 nM
   TI
   LI
   LO
   TS