Brief Information of the Compound and Protein
Compound Name
4-[2-(4-bromoanilino)quinazolin-6-yl]oxy-N-(2-piperidin-1-ylethyl)pyridine-2-carboxamide
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PubChem ID
CID: 57402861
Canonical SMILES
Brc1ccc(Nc2ncc3cc(Oc4ccnc(c4)C(=O)NCCN4CCCCC4)ccc3n2)cc1
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Compound Formula C27H27BrN6O2
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CL000313 SK-MEL-28 Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS