General Information of the Compound
| Compound ID |
CP0126581
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| Compound Name |
4-[2-(3-tert-butylanilino)quinazolin-6-yl]oxy-N-methylpyridine-2-carboxamide
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| Structure |
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| Formula |
C25H25N5O2
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| Molecular Weight |
427.508
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| Canonical SMILES |
CNC(=O)c1cc(Oc2ccc3nc(Nc4cccc(c4)C(C)(C)C)ncc3c2)ccn1
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| InChI |
InChI=1S/C25H25N5O2/c1-25(2,3)17-6-5-7-18(13-17)29-24-28-15-16-12-19(8-9-21(16)30-24)32-20-10-11-27-22(14-20)23(31)26-4/h5-15H,1-4H3,(H,26,31)(H,28,29,30)
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| InChIKey |
ZIIWAOIJFYNZSN-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound