| Compound ID |
Compound Name |
Compound Formula |
|
CP0387938
|
N-(4-carbamoylphenyl)-1-[(2-chloro-6-fluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H16ClFN4O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0506097
|
1-[(2-chloro-6-fluorophenyl)methyl]-N-(4-methylsulfonylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H17ClFN3O5S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0090555
|
1-[(2-chloro-6-fluorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H22ClFN4O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0492410
|
N-(4-acetamidophenyl)-1-[(2-chloro-6-fluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H18ClFN4O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0390794
|
1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-(methylcarbamoyl)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H18ClFN4O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0399004
|
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H21F2N3O6
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0433196
|
N-(4-acetylphenyl)-1-[(2-chloro-6-fluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H17ClFN3O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0382472
|
1-[(2-chloro-6-fluorophenyl)methyl]-4,6-dioxo-N-(4-sulfamoylphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C22H16ClFN4O5S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0382477
|
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-[4-(pyridin-4-ylmethylcarbamoyl)phenyl]-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C29H21F2N5O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0504042
|
1-[(2,6-difluorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H22F2N4O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0382495
|
N-(4-acetamidophenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H18F2N4O4
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0475449
|
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H17F2N5O5S2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0382478
|
1-[(2,6-difluorophenyl)methyl]-N-(4-methylsulfonylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H17F2N3O5S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0440285
|
1-[(2,6-difluorophenyl)methyl]-N-[4-(methylcarbamoyl)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H18F2N4O4
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0463170
|
N-(4-acetylphenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H17F2N3O4
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0372519
|
1-[(2-chloro-6-fluorophenyl)methyl]-4,6-dioxo-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H17ClFN5O5S2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0372503
|
1-[(2-chloro-6-fluorophenyl)methyl]-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H21ClFN3O6
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0372505
|
1-[(2-chloro-6-fluorophenyl)methyl]-N-(3-chloro-4-methoxyphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H16Cl2FN3O4
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0390797
|
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-(4-sulfamoylphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C22H16F2N4O5S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0492409
|
1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-(dimethylamino)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H20ClFN4O3
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0492366
|
N-(3-carbamoylphenyl)-1-[(2-chloro-6-fluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H16ClFN4O4
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0390796
|
N-[4-(diethylamino)phenyl]-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H24F2N4O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0857722
|
1-(4-(methylamino)-6-(methylthio)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
Show/Hide
|
C12H18N6S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0395377
|
N-(4-carbamoylphenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H16F2N4O4
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0382524
|
1-[(2-chloro-6-fluorophenyl)methyl]-N-(3-methylsulfonylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H17ClFN3O5S
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0070448
|
1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-(diethylamino)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H24ClFN4O3
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0399003
|
1-[(2,6-difluorophenyl)methyl]-N-[4-(dimethylamino)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H20F2N4O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0459278
|
N-[4-(difluoromethoxy)phenyl]-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H15F4N3O4
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0433194
|
1-[(2,6-difluorophenyl)methyl]-N-[4-(methylamino)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H18F2N4O3
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0390798
|
1-[(2,6-difluorophenyl)methyl]-N-(4-methylsulfanylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H17F2N3O3S
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0496073
|
1-[(2,6-dichlorophenyl)methyl]-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H21Cl2N3O6
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0382518
|
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-[4-(trifluoromethoxy)phenyl]-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H14F5N3O4
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0390793
|
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-phenyl-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C22H15F2N3O3
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0440284
|
N-(4-cyanophenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H14F2N4O3
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0382494
|
N-(4-aminophenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C22H16F2N4O3
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0382500
|
1-[(2,6-difluorophenyl)methyl]-N-(4-hydroxyphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C22H15F2N3O4
|
1
|
| 1 |
IC50 = 105 nM
|
|
|
|
CP0390795
|
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-(4-piperidin-1-ylphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C27H24F2N4O3
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0496072
|
1-[(2,6-difluorophenyl)methyl]-N-(4-methoxyphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H17F2N3O4
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0466847
|
1-[(2,6-dichlorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H22Cl2N4O4
|
1
|
| 1 |
IC50 = 165 nM
|
|
|
|
CP0382498
|
2-[4-[[1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carbonyl]amino]phenyl]acetic acid
Show/Hide
|
C24H17F2N3O5
|
1
|
| 1 |
IC50 = 176 nM
|
|
|
|
CP0459280
|
1-[(2-chlorophenyl)methyl]-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H22ClN3O6
|
1
|
| 1 |
IC50 = 178 nM
|
|
|
|
CP0395388
|
1-[(2,6-difluorophenyl)methyl]-N-(4-fluorophenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C22H14F3N3O3
|
1
|
| 1 |
IC50 = 179 nM
|
|
|
|
CP0382499
|
1-[(2,6-difluorophenyl)methyl]-N-[4-(morpholine-4-carbonyl)phenyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C27H22F2N4O5
|
1
|
| 1 |
IC50 = 188 nM
|
|
|
|
CP0475143
|
1-[(2-chloro-4-fluorophenyl)methyl]-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H21ClFN3O6
|
1
|
| 1 |
IC50 = 192 nM
|
|
|
|
CP0382497
|
4-[[1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carbonyl]amino]benzoic acid
Show/Hide
|
C23H15F2N3O5
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0513530
|
1-[(2-fluorophenyl)methyl]-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H22FN3O6
|
1
|
| 1 |
IC50 = 206 nM
|
|
|
|
CP0382519
|
1-[(2,6-difluorophenyl)methyl]-N-(3,5-dimethoxyphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C24H19F2N3O5
|
1
|
| 1 |
IC50 = 212 nM
|
|
|
|
CP0382520
|
1-[(2-methylphenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C27H26N4O4
|
1
|
| 1 |
IC50 = 266 nM
|
|
|
|
CP0387925
|
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-[4-(trifluoromethyl)phenyl]-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H14F5N3O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0459279
|
N-(4-morpholin-4-ylphenyl)-4,6-dioxo-1-[(2,3,5,6-tetrafluorophenyl)methyl]-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H20F4N4O4
|
1
|
| 1 |
IC50 = 317 nM
|
|
|
|
CP0893598
|
1-(4-methoxy-6-(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
Show/Hide
|
C12H18N6O
|
1
|
| 1 |
IC50 = 521 nM
|
|
|
|
CP0846260
|
1-(4-cyclopropyl-6-(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
Show/Hide
|
C14H20N6
|
1
|
| 1 |
IC50 = 539 nM
|
|
|
|
CP0495803
|
1-benzyl-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H23N3O6
|
1
|
| 1 |
IC50 = 686 nM
|
|
|
|
CP0433251
|
1-benzyl-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H24N4O4
|
1
|
| 1 |
IC50 = 712 nM
|
|
|
|
CP0382522
|
1-[(2-chlorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H23ClN4O4
|
1
|
| 1 |
IC50 = 767 nM
|
|
|
|
CP0399002
|
1-[(2,6-difluorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4-oxo-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H22F2N4O3
|
1
|
| 1 |
IC50 = 823 nM
|
|
|
|
CP0399005
|
1-[(4-fluorophenyl)methyl]-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H22FN3O6
|
1
|
| 1 |
IC50 = 868 nM
|
|
|
|
CP0946418
|
1-(4-(1H-imidazol-1-yl)-6-(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
Show/Hide
|
C14H18N8
|
1
|
| 1 |
IC50 = 1050 nM
|
|
|
|
CP0382496
|
N-(3-cyanophenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C23H14F2N4O3
|
1
|
| 1 |
IC50 = 1070 nM
|
|
|
|
CP0846259
|
1-(4-chloro-6-(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
Show/Hide
|
C11H15ClN6
|
1
|
| 1 |
IC50 = 1070 nM
|
|
|
|
CP0440290
|
1-[(4-fluorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H23FN4O4
|
1
|
| 1 |
IC50 = 2380 nM
|
|
|
|
CP0387923
|
1-[(3,5-difluorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H22F2N4O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0433195
|
N-(4-morpholin-4-ylphenyl)-4,6-dioxo-1-[[2-(trifluoromethyl)phenyl]methyl]-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C27H23F3N4O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0475142
|
N-(4-morpholin-4-ylphenyl)-4,6-dioxo-1-[[4-(trifluoromethoxy)phenyl]methyl]-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C27H23F3N4O5
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0492408
|
1-[(2,4-difluorophenyl)methyl]-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C26H22F2N4O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0495805
|
1-[(2-bromophenyl)methyl]-4,6-dioxo-N-(3,4,5-trimethoxyphenyl)-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C25H22BrN3O6
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0506106
|
N-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C22H13F4N3O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0846682
|
1-(4-(1H-benzo[d]imidazol-1-yl)-6-(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
Show/Hide
|
C18H20N8
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0860469
|
4-(1-cyanocyclohexylamino)-6-(methylamino)-1,3,5-triazine-2-carbonitrile
Show/Hide
|
C12H15N7
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0893586
|
1-(4,6-bis(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
Show/Hide
|
C12H19N7
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0440838
|
1-[(2,6-difluorophenyl)methyl]-6-methoxy-N-(4-morpholin-4-ylphenyl)-4-oxo-1,5-naphthyridine-3-carboxamide
Show/Hide
|
C27H24F2N4O4
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0733779
|
1-(4-(methylamino)-6-(1H-1,2,4-triazol-1-yl)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
Show/Hide
|
C13H17N9
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0846257
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1-(4-(1-cyanocyclohexylamino)-6-(methylamino)-1,3,5-triazin-2-yl)-1H-1,2,4-triazole-3-carbonitrile
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C14H16N10
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1
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| 1 |
IC50 > 5000 nM
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CP0860471
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1-(4-(3-methyl-1H-1,2,4-triazol-1-yl)-6-(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
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C14H19N9
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1
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| 1 |
IC50 > 5000 nM
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CP0862030
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1-(4-(methylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
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C17H21N7
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1
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| 1 |
IC50 > 5000 nM
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CP0876542
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1-(4-(dimethylamino)-6-(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
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C13H21N7
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1
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| 1 |
IC50 > 5000 nM
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|
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CP0886562
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1-(4-(methylamino)-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
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C15H23N7
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1
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| 1 |
IC50 > 5000 nM
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|
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CP0886723
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1-(4-(methylamino)-6-(1H-pyrazol-1-yl)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
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C14H18N8
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1
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| 1 |
IC50 > 5000 nM
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CP0953681
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1-(4-(cyclopentylamino)-6-(methylamino)-1,3,5-triazin-2-ylamino)cyclohexanecarbonitrile
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C16H25N7
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1
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| 1 |
IC50 > 5000 nM
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