General Information of the Compound
| Compound ID |
CP0475449
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| Compound Name |
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-5H-1,5-naphthyridine-3-carboxamide
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| Structure |
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| Formula |
C25H17F2N5O5S2
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| Molecular Weight |
569.571
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| Canonical SMILES |
Fc1cccc(F)c1Cn1cc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)c(=O)c2[nH]c(=O)ccc12
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| InChI |
InChI=1S/C25H17F2N5O5S2/c26-18-2-1-3-19(27)16(18)12-32-13-17(23(34)22-20(32)8-9-21(33)30-22)24(35)29-14-4-6-15(7-5-14)39(36,37)31-25-28-10-11-38-25/h1-11,13H,12H2,(H,28,31)(H,29,35)(H,30,33)
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| InChIKey |
CDTFZNYFUGFINL-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01479, 3',5'-cyclic-AMP phosphodiesterase 4A
Protein ID: PT01728, High affinity 3',5'-cyclic-AMP phosphodiesterase 7A