General Information of the Compound
| Compound ID |
CP0433251
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| Compound Name |
1-benzyl-N-(4-morpholin-4-ylphenyl)-4,6-dioxo-5H-1,5-naphthyridine-3-carboxamide
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| Structure |
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| Formula |
C26H24N4O4
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| Molecular Weight |
456.502
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| Canonical SMILES |
O=C(Nc1ccc(cc1)N1CCOCC1)c1cn(Cc2ccccc2)c2ccc(=O)[nH]c2c1=O
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| InChI |
InChI=1S/C26H24N4O4/c31-23-11-10-22-24(28-23)25(32)21(17-30(22)16-18-4-2-1-3-5-18)26(33)27-19-6-8-20(9-7-19)29-12-14-34-15-13-29/h1-11,17H,12-16H2,(H,27,33)(H,28,31)
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| InChIKey |
WVFMMBJFLNIFHY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01479, 3',5'-cyclic-AMP phosphodiesterase 4A
Protein ID: PT01728, High affinity 3',5'-cyclic-AMP phosphodiesterase 7A