General Information of the Compound
| Compound ID |
CP0390793
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| Compound Name |
1-[(2,6-difluorophenyl)methyl]-4,6-dioxo-N-phenyl-5H-1,5-naphthyridine-3-carboxamide
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| Structure |
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| Formula |
C22H15F2N3O3
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| Molecular Weight |
407.376
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| Canonical SMILES |
Fc1cccc(F)c1Cn1cc(C(=O)Nc2ccccc2)c(=O)c2[nH]c(=O)ccc12
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| InChI |
InChI=1S/C22H15F2N3O3/c23-16-7-4-8-17(24)14(16)11-27-12-15(22(30)25-13-5-2-1-3-6-13)21(29)20-18(27)9-10-19(28)26-20/h1-10,12H,11H2,(H,25,30)(H,26,28)
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| InChIKey |
ZXLBVDAFXMZACQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01479, 3',5'-cyclic-AMP phosphodiesterase 4A
Protein ID: PT01728, High affinity 3',5'-cyclic-AMP phosphodiesterase 7A