| Compound ID |
Compound Name |
Compound Formula |
|
CP0389094
|
(6aR,9R)-4-[2-(dimethylamino)ethyl]-N-phenyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C30H35N5O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0499219
|
(6aR,9R)-N-phenyl-4-(2-piperidin-1-ylethyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C33H39N5O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0377670
|
(6aR,9R)-N-phenyl-9-(pyrrolidine-1-carbonyl)-4-(2-pyrrolidin-1-ylethyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C32H37N5O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0376995
|
(6aR,9R)-N-(3-fluorophenyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H25FN4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0313657
|
(6aR,9R)-N-phenyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H26N4O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0377677
|
(6aR,9R)-4-[2-(4-methylpiperazin-1-yl)ethyl]-N-phenyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C33H40N6O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0474323
|
(6aR,9R)-4-(2-hydroxyethyl)-N-phenyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0377668
|
(6aR,9R)-N-(4-fluorophenyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H25FN4O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0510626
|
2-[4-chloro-2-imino-3-[2-[(2S)-1-(quinoline-8-carbonyl)pyrrolidin-2-yl]ethyl]benzimidazol-1-yl]-1-(4-chlorophenyl)ethanone
Show/Hide
|
C31H27Cl2N5O2
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0290839
|
(6aR,9R)-N-phenyl-9-(piperidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H28N4O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0422593
|
N-[3-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N-cyclopropylquinoline-8-carboxamide
Show/Hide
|
C31H27Cl2N5O2
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0503412
|
(6aR,9R)-9-(3,4-dihydro-2H-pyridine-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H26N4O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0342761
|
(6aR,9R)-9-(4-hydroxypiperidine-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H28N4O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0405099
|
N-[3-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N-methylnaphthalene-2-carboxamide
Show/Hide
|
C30H26Cl2N4O2
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0422598
|
2-[4-chloro-2-imino-3-[[(3S)-1-(quinoline-8-carbonyl)piperidin-3-yl]methyl]benzimidazol-1-yl]-1-(4-chlorophenyl)ethanone
Show/Hide
|
C31H27Cl2N5O2
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0862182
|
2-{4-chloro-2-imino-3-[1-(quinoline-8-carbonyl)-piperidin-3-ylmethyl]-2,3-dihydro-benzoimidazol-1-yl}-1-(4-chloro-phenyl)-ethanone
Show/Hide
|
C31H27Cl2N5O2
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0424828
|
2-[4-chloro-2-imino-3-[[(3R)-1-(quinoline-8-carbonyl)piperidin-3-yl]methyl]benzimidazol-1-yl]-1-(4-chlorophenyl)ethanone
Show/Hide
|
C31H27Cl2N5O2
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0436502
|
(6aR,9R)-9-(2,5-dihydropyrrole-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H24N4O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0372900
|
N-[3-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N-methylpyridine-2-carboxamide
Show/Hide
|
C25H23Cl2N5O2
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
|
CP0372901
|
N-[3-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N-methylbenzamide
Show/Hide
|
C26H24Cl2N4O2
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 300 nM
|
|
|
|
CP0394830
|
N-[3-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N-methylquinoline-8-carboxamide
Show/Hide
|
C29H25Cl2N5O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0394832
|
N-[3-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-2-methoxy-N-methylbenzamide
Show/Hide
|
C27H26Cl2N4O3
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 50 nM
|
|
|
|
CP0397994
|
(6aR,9R)-9-(morpholine-4-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H26N4O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0376993
|
(6aR,9R)-N-cyclohexyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H32N4O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0498359
|
(6aR,9R)-4-(2-morpholin-4-ylethyl)-N-phenyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C32H37N5O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0397997
|
(6aR,9R)-9-(pyrrolidine-1-carbonyl)-N-thiophen-3-yl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C24H24N4O2S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0397993
|
(6aR,9R)-9-N,9-N-dimethyl-7-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7,9-dicarboxamide
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0397998
|
(6aR,9R)-N-cycloheptyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H34N4O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0440972
|
1-(4-chlorophenyl)-2-(4-ethyl-2-imino-3-methylbenzimidazol-1-yl)ethanone
Show/Hide
|
C18H18ClN3O
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 70 nM
|
|
|
|
CP0502922
|
(6aR,9R)-9-(pyrrolidine-1-carbonyl)-N-thiophen-2-yl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C24H24N4O2S
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0397995
|
(6aR,9R)-N-(2-fluorophenyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H25FN4O2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0390114
|
(6aR,9R)-9-[(3S)-3-hydroxypyrrolidine-1-carbonyl]-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H26N4O3
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0376988
|
(6aR,9R)-9-[(3S,4R)-3,4-dihydroxypiperidine-1-carbonyl]-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H28N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0095029
|
(6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C26H28N4O2
|
2
|
| 1 |
IC50 = 51 nM
|
|
|
| 2 |
IC50 = 54 nM
|
|
|
|
CP0376991
|
(6aR,9R)-9-(azetidine-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C25H24N4O2
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0458345
|
(6aR,9R)-9-[(3R)-3-hydroxypyrrolidine-1-carbonyl]-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H26N4O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0376990
|
(6aR,9R)-9-N-(2-hydroxyethyl)-9-N-methyl-7-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7,9-dicarboxamide
Show/Hide
|
C25H26N4O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0412570
|
N-[3-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H26Cl2N4O2
|
2
|
| 1 |
IC50 = 70 nM
|
|
|
| 2 |
IC50 = 300 nM
|
|
|
|
CP0419591
|
1-[2-[4-[[1-(2,3-dihydro-1-benzofuran-5-yl)ethyl-methylamino]methyl]-2-methoxyphenoxy]ethyl]pyrrolidine-2,5-dione
Show/Hide
|
C25H30N2O5
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0524203
|
1-(4-chlorophenyl)-2-(2-imino-3,4-dimethylbenzimidazol-1-yl)ethanone
Show/Hide
|
C17H16ClN3O
|
2
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0502921
|
(6aR,9R)-9-(azepane-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C28H30N4O2
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0486726
|
N-[3-[3-[2-(4-chlorophenyl)-2-oxoethyl]-7-ethyl-2-iminobenzimidazol-1-yl]propyl]-N-methyl-2-phenylacetamide
Show/Hide
|
C29H31ClN4O2
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
|
CP0376992
|
(6aR,9R)-9-(4-methylpiperazine-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H29N5O2
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0390116
|
propan-2-yl 2-[(6aR,9R)-7-(phenylcarbamoyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinolin-4-yl]acetate
Show/Hide
|
C31H34N4O4
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0471986
|
(6aR,9R)-N9,N9-diethyl-N7-o-tolyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0463248
|
(+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-1-carbaldehyde
Show/Hide
|
C24H29BrN2O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0377675
|
(6aR,9R)-N-cyclopentyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0440611
|
(+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiperidin-3-yl)-4-methoxybenzenesulfonic acid
Show/Hide
|
C24H27BrN2O6S
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0401250
|
(6aR,9R)-N7-cyclohexyl-N9,N9-diethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
IC50 = 179 nM
|
|
|
|
CP0399941
|
(+/-)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)cyclopropanone
Show/Hide
|
C26H31BrN2O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0424829
|
N-benzyl-3-[3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]-N-methylpropanamide
Show/Hide
|
C26H25ClN4O2
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 400 nM
|
|
|
|
CP0460418
|
(+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-1-sulfonamide
Show/Hide
|
C23H30BrN3O2S
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0461198
|
(6aR,9R)-N9,N9-diethyl-4-methyl-N7-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0508326
|
(6aR,9R)-N9,N9-diethyl-N7-m-tolyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 231 nM
|
|
|
|
CP0440612
|
(+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-1-carboxamide
Show/Hide
|
C24H30BrN3O
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0530461
|
(6aR,9R)-9-(3-oxopiperazine-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H25N5O3
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
|
CP0377674
|
(6aR,9R)-N-(3-methoxyphenyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H28N4O3
|
1
|
| 1 |
IC50 = 278 nM
|
|
|
|
CP0471988
|
(6aR,9R)-N9,N9-diethyl-N7-(pyridin-3-yl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C25H27N5O2
|
1
|
| 1 |
IC50 = 285 nM
|
|
|
|
CP0389643
|
(+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)propan-1-one
Show/Hide
|
C26H33BrN2O
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0454299
|
2-(4-chloro-2-imino-3-methylbenzimidazol-1-yl)-1-(4-chlorophenyl)ethanone
Show/Hide
|
C16H13Cl2N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0422591
|
N-[2-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]ethyl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H24Cl2N4O2
|
2
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
IC50 = 400 nM
|
|
|
|
CP0467154
|
N-[2-[3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]ethyl]-N-methylbenzamide
Show/Hide
|
C25H23ClN4O2
|
2
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
IC50 = 2300 nM
|
|
|
|
CP0380675
|
(6aR,9R)-9-N,9-N-bis(2-methoxyethyl)-7-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7,9-dicarboxamide
Show/Hide
|
C28H32N4O4
|
1
|
| 1 |
IC50 = 305 nM
|
|
|
|
CP0499116
|
(6aR,9R)-N9,N9-diethyl-N7-p-tolyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 313 nM
|
|
|
|
CP0486411
|
(+/-)-3-(3-aminophenyl)-1'-(4-bromobenzyl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H26BrN3O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0486413
|
(+/-)-ethyl 1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-1-carboxylate
Show/Hide
|
C26H33BrN2O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0095851
|
(-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(pyridin-3-ylmethyl)-2-(4-(trifluoromethoxy)phenyl)acetamide
Show/Hide
|
C32H28F3N5O4
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0528356
|
(-)-1'-(4-chloro-3-fluorobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H24ClFN2O2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0390112
|
(6aR,9R)-9-N-ethyl-7-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7,9-dicarboxamide
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
IC50 = 379 nM
|
|
|
|
CP0503409
|
(6aR,9R)-N-(4-methoxyphenyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H28N4O3
|
1
|
| 1 |
IC50 = 393 nM
|
|
|
|
CP0462427
|
1-(4-chlorophenyl)-2-(2-imino-3-methyl-4-propylbenzimidazol-1-yl)ethanone
Show/Hide
|
C19H20ClN3O
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 500 nM
|
|
|
|
CP0405097
|
N-[3-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propyl]-N,2,2-trimethylpropanamide
Show/Hide
|
C24H28Cl2N4O2
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 600 nM
|
|
|
|
CP0471150
|
N-[4-[7-chloro-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]butyl]-N-methyl-2-phenylacetamide
Show/Hide
|
C28H28Cl2N4O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0461668
|
N-[2-[3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]ethyl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H25ClN4O2
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 800 nM
|
|
|
|
CP0458346
|
(6aR,9R)-9-(1,1-dioxo-1,4-thiazinane-4-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H26N4O4S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0493962
|
1-[(6aR,9R)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-7-yl]-2-phenylethanone
Show/Hide
|
C27H27N3O2
|
1
|
| 1 |
IC50 = 427 nM
|
|
|
|
CP0473971
|
(6aR,9R)-N9,N9-diethyl-N7-(pyridin-2-yl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C25H27N5O2
|
1
|
| 1 |
IC50 = 428 nM
|
|
|
|
CP0463243
|
(+/-)-1'-(4-bromobenzyl)-3-(pyridin-2-yl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C22H24BrN3O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0528360
|
(+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-6-one
Show/Hide
|
C23H27BrN2O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0422597
|
N-[2-[3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]ethyl]-N-methylcyclohexanecarboxamide
Show/Hide
|
C25H29ClN4O2
|
2
|
| 1 |
IC50 = 500 nM
|
|
|
| 2 |
IC50 = 900 nM
|
|
|
|
CP0505312
|
(6aR,9R)-N-(2-methoxyphenyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H28N4O3
|
1
|
| 1 |
IC50 = 523 nM
|
|
|
|
CP0461199
|
(6aR,9R)-4-benzyl-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C33H34N4O2
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0463245
|
(+/-)-1'-(4-bromobenzyl)-3-(pyridin-4-yl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C22H24BrN3O2
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0527009
|
(+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiperidin-3-yl)benzoic acid
Show/Hide
|
C24H25BrN2O4
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0399940
|
(+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-1-yl)-2,2,2-trifluoroethanone
Show/Hide
|
C25H28BrF3N2O
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0372769
|
1-(4-chlorophenyl)-2-[2-imino-3-methyl-4-(trifluoromethyl)benzimidazol-1-yl]ethanone
Show/Hide
|
C17H13ClF3N3O
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0405098
|
1-(4-chlorophenyl)-2-(3-ethyl-2-iminobenzimidazol-1-yl)ethanone
Show/Hide
|
C17H16ClN3O
|
2
|
| 1 |
IC50 = 700 nM
|
|
|
| 2 |
IC50 = 3500 nM
|
|
|
|
CP0486410
|
(+/-)-1'-(4-bromobenzyl)-3-(3-(morpholine-4-carbonyl)phenyl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C28H32BrN3O4
|
1
|
| 1 |
IC50 = 790 nM
|
|
|
|
CP0372768
|
1-(4-bromophenyl)-2-(2-imino-4-methoxy-3-methylbenzimidazol-1-yl)ethanone
Show/Hide
|
C17H16BrN3O2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0372772
|
1-(4-bromophenyl)-2-(2-imino-3-methyl-1-benzimidazolyl)ethanone;hydrobromide
Show/Hide
|
C16H14BrN3O
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0457815
|
1-(4-chlorophenyl)-2-(2-imino-3-methyl-1-benzimidazolyl)ethanone;hydrobromide
Show/Hide
|
C16H14ClN3O
|
2
|
| 1 |
IC50 = 800 nM
|
|
|
| 2 |
IC50 = 9000 nM
|
|
|
|
CP0935522
|
1-(4-chloro-phenyl)-2-{3-methyl-2-[methylimino]-2,3-dihydro-benzoimidazol-1-yl}-ethanone
Show/Hide
|
C17H16ClN3O
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0499147
|
(6aR,9R)-phenyl 9-(diethylcarbamoyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7(4H)-carboxylate
Show/Hide
|
C26H27N3O3
|
1
|
| 1 |
IC50 = 803 nM
|
|
|
|
CP0377672
|
(6aR,9R)-9-(4-acetylpiperazine-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C28H29N5O3
|
1
|
| 1 |
IC50 = 825 nM
|
|
|
|
CP0389641
|
(+/-)-1'-(4-chlorobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H25ClN2O2
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0463247
|
(+/-)-1'-(4-bromobenzyl)-3-(3-hydroxyphenyl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H25BrN2O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0486412
|
(+/-)-1'-(4-bromobenzyl)-1-(methylthiomethyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C25H29BrN2O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0527007
|
(+/-)-1'-(4-bromobenzyl)-3-(pyridin-3-yl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C22H24BrN3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0457818
|
1-(4-chlorophenyl)-2-(2-imino-3,5-dimethylbenzimidazol-1-yl)ethanone
Show/Hide
|
C17H16ClN3O
|
2
|
| 1 |
IC50 = 1000 nM
|
|
|
| 2 |
IC50 = 5000 nM
|
|
|
|
CP0890181
|
1-(4-bromo-phenyl)-2-{2-[2-methoxy-ethylimino]-3-methyl-2,3-dihydro-benzoimidazol-1-yl}-ethanone
Show/Hide
|
C19H20BrN3O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0458347
|
(6aR,9R)-N-phenyl-9-(piperazine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C26H27N5O2
|
1
|
| 1 |
IC50 = 1010 nM
|
|
|
|
CP0394831
|
1-(4-chlorophenyl)-2-(2-imino-3-propyl-1-benzimidazolyl)ethanone;hydrobromide
Show/Hide
|
C18H18ClN3O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0527363
|
(6aR,9R)-9-(2,6-dimethylmorpholine-4-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C28H30N4O3
|
1
|
| 1 |
IC50 = 1160 nM
|
|
|
|
CP0454058
|
ethyl 3-[3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]propanoate
Show/Hide
|
C20H20ClN3O3
|
2
|
| 1 |
IC50 = 1200 nM
|
|
|
| 2 |
IC50 = 2500 nM
|
|
|
|
CP0399937
|
(+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiperidin-3-yl)-N-methyl-N-(piperazin-1-yl)benzamide
Show/Hide
|
C29H36BrN5O3
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0486409
|
(+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiperidin-3-yl)-N-(3-hydroxypropyl)benzamide
Show/Hide
|
C27H32BrN3O4
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0503067
|
(+/-)-1'-(4-bromobenzyl)-3-(4-fluorophenyl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H24BrFN2O2
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0506320
|
(+/-)-1'-(3,4-dichlorobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H24Cl2N2O2
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0457717
|
N-[2-[3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]ethyl]-N-methylacetamide
Show/Hide
|
C20H21ClN4O2
|
2
|
| 1 |
IC50 = 1300 nM
|
|
|
| 2 |
IC50 = 3400 nM
|
|
|
|
CP0495734
|
(+/-)-1'-(4-bromobenzyl)-3-(3-chlorophenyl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H24BrClN2O2
|
1
|
| 1 |
IC50 = 1450 nM
|
|
|
|
CP0506321
|
(+/-)-1'-(4-bromobenzyl)-3-(3-methoxyphenyl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C24H27BrN2O3
|
1
|
| 1 |
IC50 = 1550 nM
|
|
|
|
CP0486414
|
(+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin-2-one
Show/Hide
|
C23H27BrN2O
|
1
|
| 1 |
IC50 = 1580 nM
|
|
|
|
CP0399939
|
(+/-)-1'-(4-bromobenzyl)-1-(2-methoxyethyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C26H31BrN2O3
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0433255
|
2-(2-acetylbenzimidazol-1-yl)-1-(4-bromophenyl)ethanone
Show/Hide
|
C17H13BrN2O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0439316
|
(6aR,9R)-N9,N9-diethyl-N7-(pyridin-4-yl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C25H27N5O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0477818
|
N-benzyl-2-[3-[2-(4-chlorophenyl)-2-oxoethyl]-2-iminobenzimidazol-1-yl]-N-methylacetamide
Show/Hide
|
C25H23ClN4O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0498358
|
(6aR,9R)-N-benzyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C27H28N4O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0525999
|
(+/-)-1'-(4-methylbenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0389642
|
(+/-)-1'-(4-chloro-3-(trifluoromethyl)benzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C24H24ClF3N2O2
|
1
|
| 1 |
IC50 = 2510 nM
|
|
|
|
CP0399938
|
(+/-)-1'-(4-bromobenzyl)-1-methyl-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C24H27BrN2O2
|
1
|
| 1 |
IC50 = 2510 nM
|
|
|
|
CP0528358
|
(+/-)-1'-(4-bromobenzyl)-1-ethyl-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C25H29BrN2O2
|
1
|
| 1 |
IC50 = 2510 nM
|
|
|
|
CP0512848
|
(6aR,9R)-N-(furan-2-ylmethyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
Show/Hide
|
C25H26N4O3
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0378992
|
2-(2-acetylbenzimidazol-1-yl)-1-(4-nitrophenyl)ethanone
Show/Hide
|
C17H13N3O4
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0440971
|
2-(2-acetyl-4-methoxybenzimidazol-1-yl)-1-(4-bromophenyl)ethanone
Show/Hide
|
C18H15BrN2O3
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0457814
|
1-[(4-chlorophenyl)sulfinylmethyl]-3-methylbenzimidazol-2-imine
Show/Hide
|
C15H14ClN3OS
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0401249
|
(6aR,9R)-N9,N9-diethyl-N7-(3,4,5-trimethoxyphenyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C29H34N4O5
|
1
|
| 1 |
IC50 = 3050 nM
|
|
|
|
CP0399366
|
(+/-)-1'-(2,4-dichlorobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H24Cl2N2O2
|
1
|
| 1 |
IC50 = 3160 nM
|
|
|
|
CP0417577
|
(+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiperidin-3-yl)benzamide
Show/Hide
|
C24H26BrN3O3
|
1
|
| 1 |
IC50 = 3160 nM
|
|
|
|
CP0486408
|
(+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiperidin-3-yl)-N-methylbenzamide
Show/Hide
|
C25H28BrN3O3
|
1
|
| 1 |
IC50 = 3160 nM
|
|
|
|
CP0528357
|
(+/-)-1'-(4-bromobenzyl)-3-(4-methoxyphenyl)-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C24H27BrN2O3
|
1
|
| 1 |
IC50 = 3630 nM
|
|
|
|
CP0562514
|
1-(3,4-dichlorophenyl)-2-(2-imino-3-methyl-1-benzimidazolyl)ethanone;hydrobromide
Show/Hide
|
C16H13Cl2N3O
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0465756
|
(+/-)-1'-(4-methoxybenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C24H28N2O3
|
1
|
| 1 |
IC50 = 4270 nM
|
|
|
|
CP0527006
|
(+/-)-1'-(4-fluorobenzyl)-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H25FN2O2
|
1
|
| 1 |
IC50 = 4570 nM
|
|
|
|
CP0455935
|
(+/-)-1'-(4-bromobenzyl)-3-phenyl-1-propyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C26H31BrN2O2
|
1
|
| 1 |
IC50 = 5010 nM
|
|
|
|
CP0490279
|
(+/-)-4-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiperidin-3-yl)benzoic acid
Show/Hide
|
C24H25BrN2O4
|
1
|
| 1 |
IC50 = 5010 nM
|
|
|
|
CP0528359
|
(+/-)-1'-(4-bromobenzyl)-1-isopropyl-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C26H31BrN2O2
|
1
|
| 1 |
IC50 = 5010 nM
|
|
|
|
CP0453838
|
(6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0462425
|
1-(4-bromophenyl)-4-(2-imino-3-methylbenzimidazol-1-yl)butan-1-one
Show/Hide
|
C18H18BrN3O
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0457817
|
2-(2-acetylbenzimidazol-1-yl)-1-(4-chlorophenyl)ethanone
Show/Hide
|
C17H13ClN2O2
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0467718
|
1-(4-chlorophenyl)-2-(2-imino-3,6-dimethylbenzimidazol-1-yl)ethanone
Show/Hide
|
C17H16ClN3O
|
1
|
| 1 |
IC50 = 8000 nM
|
|
|
|
CP0077621
|
(+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0528361
|
(+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine
Show/Hide
|
C23H29BrN2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0095027
|
(6aR,9R)-N,N-diethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0471984
|
(6aR,9R)-N9,N9-diethyl-N7-methyl-N7-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0471991
|
(6aR,9S)-9-((diethylamino)methyl)-N-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7(4H)-carboxamide
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C26H30N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0499135
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(6aR,9S)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
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C26H28N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0377669
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(6aR,9R)-N-(4-hydroxycyclohexyl)-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
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C26H32N4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0397996
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(6aR,9R)-N-methyl-9-(pyrrolidine-1-carbonyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
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C21H24N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0436500
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(6aR,9R)-7-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7,9-dicarboxamide
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C22H20N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0436504
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[(6aR,9R)-7-benzoyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-pyrrolidin-1-ylmethanone
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C26H25N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0502902
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(6aR,9R)-9-(pyrrolidine-1-carbonyl)-N-(1H-pyrrol-3-yl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
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C24H25N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0440969
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2-(2-methylsulfinylbenzimidazol-1-yl)-1-(4-nitrophenyl)ethanone
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C16H13N3O4S
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1
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| 1 |
IC50 = 11000 nM
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CP0457812
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1-[2-(4-bromophenyl)ethyl]-3-methylbenzimidazol-2-imine
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C16H16BrN3
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1
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| 1 |
IC50 = 11000 nM
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CP0524204
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1-(3-chlorophenyl)-2-(2-imino-3-methylbenzimidazol-1-yl)ethanone
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C16H14ClN3O
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1
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| 1 |
IC50 = 16000 nM
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CP0527997
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2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-1-(4-nitrophenyl)ethanone
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C17H15N3O4
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1
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| 1 |
IC50 = 20000 nM
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CP0372771
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1-(2-chlorophenyl)-2-(2-imino-3-methylbenzimidazol-1-yl)ethanone
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C16H14ClN3O
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1
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| 1 |
IC50 = 22000 nM
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CP0372770
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1-(4-bromophenyl)-2-(2-imino-3-methylbenzimidazol-1-yl)ethanol
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C16H16BrN3O
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1
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| 1 |
IC50 = 40000 nM
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CP0440970
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2-(2-acetyl-6-phenylbenzimidazol-1-yl)-1-(4-bromophenyl)ethanone
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C23H17BrN2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0457816
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2-(2-acetyl-5-phenylbenzimidazol-1-yl)-1-(4-bromophenyl)ethanone
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C23H17BrN2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0471406
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2-(2-acetyl-5-methoxybenzimidazol-1-yl)-1-(4-bromophenyl)ethanone
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C18H15BrN2O3
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1
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| 1 |
IC50 > 50000 nM
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CP0524205
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2-(2-acetyl-6-methoxybenzimidazol-1-yl)-1-(4-bromophenyl)ethanone
Show/Hide
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C18H15BrN2O3
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1
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| 1 |
IC50 > 50000 nM
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CP0935523
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N-[1-methyl-3-[2-(4-nitro-phenyl)-2-oxo-ethyl]-1,3-dihydro-benzoimidazol-(2)-ylidene]-acetamide
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C18H16N4O4
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1
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| 1 |
IC50 = 50000 nM
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CP0454300
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4-[2-(2-acetylbenzimidazol-1-yl)acetyl]benzonitrile
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C18H13N3O2
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1
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| 1 |
IC50 > 100000 nM
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CP0527998
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2-(2-acetylbenzimidazol-1-yl)-1-phenylethanone
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C17H14N2O2
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1
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| 1 |
IC50 > 100000 nM
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CP0528004
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1-[3-[[(1R,5S)-3-[[6-(trifluoromethyl)quinolin-2-yl]amino]-8-azabicyclo[3.2.1]octan-8-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
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C28H33F3N4O
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1
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| 1 |
Ki = 3 nM
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CP0502034
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1-[3-[[(1R,5S)-3-[[7-(trifluoromethyl)quinolin-2-yl]amino]-8-azabicyclo[3.2.1]octan-8-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
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C28H33F3N4O
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1
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| 1 |
Ki = 4 nM
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CP0528003
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1-[3-[[(1R,5S)-3-[(7-propan-2-yloxyquinolin-2-yl)amino]-8-azabicyclo[3.2.1]octan-8-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C30H40N4O2
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1
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| 1 |
Ki = 5 nM
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CP0462537
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1-[3-[[(1R,5S)-3-[[6-(trifluoromethoxy)quinolin-2-yl]amino]-8-azabicyclo[3.2.1]octan-8-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
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C28H33F3N4O2
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1
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| 1 |
Ki = 6 nM
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CP0502033
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1-[3-[[(1R,5S)-3-[(5-fluoro-7-propan-2-yloxyquinolin-2-yl)amino]-8-azabicyclo[3.2.1]octan-8-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C30H39FN4O2
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1
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| 1 |
Ki = 6 nM
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CP0524218
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1-[3-[[4-[[7-(trifluoromethyl)quinolin-2-yl]amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
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C26H31F3N4O
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1
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| 1 |
Ki = 7 nM
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CP0405156
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1-(1-((9-acetyl-9-aza-bicyclo[3.3.1]non-2-en-3-yl)methyl)piperidin-4-yl)-3-(3-fluoro-5-(trifluoromethyl)phenyl)urea
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C24H30F4N4O2
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1
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| 1 |
Ki = 9 nM
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CP0169626
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1-[3-[[4-[[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
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C26H29F6N5O
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1
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| 1 |
Ki = 15 nM
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CP0405569
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(3-fluoro-5-(trifluoromethyl)phenyl)urea
Show/Hide
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C23H29F4N3O
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1
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| 1 |
Ki = 16 nM
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CP0452786
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1-[3-[[4-[[6-(trifluoromethoxy)quinolin-2-yl]amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C26H31F3N4O2
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1
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| 1 |
Ki = 18 nM
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CP0457524
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1-[3-[[4-[(5-fluoro-7-methoxyquinolin-2-yl)amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C26H33FN4O2
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1
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| 1 |
Ki = 20 nM
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CP0462540
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1-[3-[[4-[[6-(trifluoromethyl)quinolin-2-yl]amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C26H31F3N4O
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1
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| 1 |
Ki = 21 nM
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CP0462538
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1-[3-[[4-[(5-fluoro-7-propan-2-yloxyquinolin-2-yl)amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C28H37FN4O2
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1
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| 1 |
Ki = 24 nM
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CP0462539
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1-[3-[[4-[(7-propan-2-yloxyquinolin-2-yl)amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C28H38N4O2
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1
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| 1 |
Ki = 25 nM
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CP0372922
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1-[3-[[4-[(6-chloroquinolin-2-yl)amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C25H31ClN4O
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1
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| 1 |
Ki = 26 nM
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CP0526238
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1-{[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methyl}-4-({[3-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-1-methylpiperidin-1-ium iodide
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C24H32F4IN3O
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1
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| 1 |
Ki = 28 nM
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CP0425143
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(5-(3-methoxyphenyl)thiophen-2-yl)urea
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C27H35N3O2S
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1
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| 1 |
Ki = 29 nM
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CP0444447
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(3-(trifluoromethoxy)phenyl)urea
Show/Hide
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C23H30F3N3O2
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1
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| 1 |
Ki = 31 nM
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CP0501067
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1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(cyclooctenylmethyl)piperidin-4-yl)urea
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C23H29F6N3O
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1
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| 1 |
Ki = 36 nM
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CP0373626
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(5-(4-(trifluoromethyl)phenyl)thiophen-2-yl)urea
Show/Hide
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C27H32F3N3OS
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1
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| 1 |
Ki = 39 nM
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CP0427410
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1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3,5-dichlorophenyl)urea
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C21H29Cl2N3O
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1
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| 1 |
Ki = 41 nM
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CP0442361
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1-(5-(2-chlorophenyl)thiophen-2-yl)-3-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C26H32ClN3OS
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1
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| 1 |
Ki = 46 nM
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CP0532307
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1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3-fluoro-5-(trifluoromethyl)phenyl)urea
Show/Hide
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C22H29F4N3O
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1
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| 1 |
Ki = 47 nM
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CP0501071
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(5-(thiophen-2-yl)pyridin-3-yl)urea
Show/Hide
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C25H32N4OS
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1
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| 1 |
Ki = 70 nM
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CP0341401
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1-(3,5-bis(trifluoromethyl)phenyl)-3-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C24H29F6N3O
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1
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| 1 |
Ki = 73 nM
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CP0528614
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(4-fluoro-3-(trifluoromethyl)phenyl)urea
Show/Hide
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C23H29F4N3O
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1
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| 1 |
Ki = 81 nM
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CP0505619
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(3-fluoro-5-(tetrahydrofuran-3-yloxy)phenyl)urea
Show/Hide
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C26H36FN3O3
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1
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| 1 |
Ki = 83 nM
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CP0444445
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1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea
Show/Hide
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C22H30F3N3O
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1
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| 1 |
Ki = 88 nM
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CP0457836
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1-[3-[[4-[1,3-benzothiazol-2-yl(methyl)amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C24H32N4OS
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1
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| 1 |
Ki = 95 nM
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CP0428699
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1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3-(trifluoromethoxy)phenyl)urea
Show/Hide
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C22H30F3N3O2
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1
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| 1 |
Ki = 104 nM
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CP0458902
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(5-(thiophen-3-yl)pyridin-3-yl)urea
Show/Hide
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C25H32N4OS
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1
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| 1 |
Ki = 107 nM
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CP0532311
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1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(5-phenylthiophen-2-yl)urea
Show/Hide
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C25H33N3OS
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1
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| 1 |
Ki = 108 nM
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CP0201649
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(E)-1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(naphthalen-2-yl)urea
Show/Hide
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C25H33N3O
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1
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| 1 |
Ki = 110 nM
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CP0264565
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N-[1-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]piperidin-4-yl]-N-methyl-1,3-benzothiazol-2-amine
Show/Hide
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C23H31N3S
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1
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| 1 |
Ki = 126 nM
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CP0037263
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1-[3-[[4-(quinolin-2-ylamino)piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C25H32N4O
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1
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| 1 |
Ki = 135 nM
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CP0501070
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(3-(tetrahydrofuran-3-yloxy)phenyl)urea
Show/Hide
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C26H37N3O3
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1
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| 1 |
Ki = 141 nM
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CP0222641
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1-[3-[[4-(quinoxalin-2-ylamino)piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
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C24H31N5O
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1
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| 1 |
Ki = 143 nM
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CP0442363
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1-(3,5-difluorophenyl)-3-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C22H29F2N3O
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1
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| 1 |
Ki = 171 nM
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CP0505308
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1-(5-bromopyridin-3-yl)-3-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C21H29BrN4O
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1
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| 1 |
Ki = 171 nM
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CP0465169
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea
Show/Hide
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C23H30F3N3O2
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1
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| 1 |
Ki = 175 nM
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CP0428701
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(3-(tetrahydro-2H-pyran-4-yloxy)phenyl)urea
Show/Hide
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C27H39N3O3
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1
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| 1 |
Ki = 191 nM
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CP0428702
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(5-phenylthiophen-2-yl)urea
Show/Hide
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C26H33N3OS
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1
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| 1 |
Ki = 191 nM
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CP0444446
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1-(3-chlorophenyl)-3-(1-(cyclooctenylmethyl)piperidin-4-yl)urea
Show/Hide
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C21H30ClN3O
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1
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| 1 |
Ki = 201 nM
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CP0497151
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
Show/Hide
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C23H29F4N3O
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1
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| 1 |
Ki = 229 nM
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CP0428703
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1-(3-acetylphenyl)-3-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C24H33N3O2
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1
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| 1 |
Ki = 258 nM
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CP0501068
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1-(1-(2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethyl)piperidin-4-yl)-3-(naphthalen-2-yl)urea
Show/Hide
|
C27H35N3O
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1
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| 1 |
Ki = 290 nM
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CP0505306
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1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(4-phenoxyphenyl)urea
Show/Hide
|
C27H35N3O2
|
1
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| 1 |
Ki = 306 nM
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CP0532313
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methyl 3-[[1-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]piperidin-4-yl]carbamoylamino]benzoate
Show/Hide
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C24H33N3O3
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1
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| 1 |
Ki = 376 nM
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CP0444448
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-(3-methoxyphenyl)urea
Show/Hide
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C23H33N3O2
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1
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| 1 |
Ki = 429 nM
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CP0440973
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1-[3-[[4-[(8-chloroquinolin-2-yl)amino]piperidin-1-yl]methyl]-9-azabicyclo[3.3.1]non-2-en-9-yl]ethanone
Show/Hide
|
C25H31ClN4O
|
1
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| 1 |
Ki = 624 nM
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CP0427822
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1-(3-acetylphenyl)-3-(1-(cyclooctenylmethyl)piperidin-4-yl)urea
Show/Hide
|
C23H33N3O2
|
1
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| 1 |
Ki = 637 nM
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CP0532309
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methyl 3-[[1-[[(1E)-cycloocten-1-yl]methyl]piperidin-4-yl]carbamoylamino]benzoate
Show/Hide
|
C23H33N3O3
|
1
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| 1 |
Ki = 660 nM
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CP0465166
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1-(4-tert-butylphenyl)-3-(1-(cyclooctenylmethyl)piperidin-4-yl)urea
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C25H39N3O
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1
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| 1 |
Ki = 1040 nM
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CP0505307
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1-(naphthalen-2-yl)-3-(1-phenethylpiperidin-4-yl)urea
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C24H27N3O
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1
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| 1 |
Ki = 1300 nM
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CP0420172
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1-(1-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)piperidin-4-yl)-3-phenylurea
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C22H31N3O
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1
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| 1 |
Ki = 2000 nM
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CP0501069
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1-(naphthalen-2-yl)-3-(1-(3-phenylpropyl)piperidin-4-yl)urea
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C25H29N3O
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1
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| 1 |
Ki = 2200 nM
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CP0373624
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1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3,5-dichloropyridin-4-yl)urea
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C20H28Cl2N4O
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1
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| 1 |
Ki = 3400 nM
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