Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide
    Show/Hide
 PubChem ID
CID: 45482789
SID: 96027643
Canonical SMILES
CCN(CC)C(=O)[C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)Nc1ccccc1
    Show/Hide
Compound Formula C26H28N4O2
Compound Structure
Protein Name
 Protein Info 
C-X-C chemokine receptor type 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P49682
Gene Name
CXCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
2
IC50 = 54 nM
   TI
   LI
   LO
   TS
CL000233 L1.2
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
2
IC50 = 74 nM
   TI
   LI
   LO
   TS