Brief Information of the Compound and Protein
Compound Name
(6aR,9R)-9-(azepane-1-carbonyl)-N-phenyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-7-carboxamide
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PubChem ID
CID: 56660100
Canonical SMILES
O=C(Nc1ccccc1)N1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N1CCCCCC1
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Compound Formula C28H30N4O2
Compound Structure
Protein Name
C-X-C chemokine receptor type 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P49682
Gene Name
CXCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 81 nM
   TI
   LI
   LO
   TS
CL000233 L1.2 Mus musculus (Mouse)  1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS