| Compound ID |
Compound Name |
Compound Formula |
|
CP0567389
|
(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-[3-(1H-indol-3-yl)propanoylamino]-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide
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C45H58N12O6
|
1
|
| 1 |
EC50 = 0.022 nM
|
|
|
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CP0474394
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N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]benzamide
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C41H53N11O6
|
1
|
| 1 |
EC50 = 0.024 nM
|
|
|
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CP0571054
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N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]cyclopropanecarboxamide
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C38H53N11O6
|
1
|
| 1 |
EC50 = 0.028 nM
|
|
|
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CP0438590
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N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]pyridine-2-carboxamide
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C40H52N12O6
|
1
|
| 1 |
EC50 = 0.037 nM
|
|
|
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CP0367958
|
(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
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C59H78N16O12
|
2
|
| 1 |
EC50 = 0.057 nM
|
|
|
| 2 |
Ki = 0.044 nM
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CP0534680
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(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-4-methyl-2-[[[(2S)-2-(2-methylpropanoylamino)-3-phenylpropanoyl]amino]carbamoylamino]pentanamide
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C38H55N11O6
|
1
|
| 1 |
EC50 = 0.058 nM
|
|
|
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CP0352243
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N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]pyridine-4-carboxamide
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|
C40H52N12O6
|
1
|
| 1 |
EC50 = 0.068 nM
|
|
|
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CP0039237
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(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]butanediamido]-3-(1H-indol-3-yl)propanamido]-N-[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]butanediamide
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|
C63H83N17O14
|
7
|
| 1 |
EC50 = 0.087 nM
|
|
|
| 2 |
EC50 = 0.24 nM
|
|
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| 3 |
EC50 = 0.96 nM
|
|
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| 4 |
IC50 = 0.07 nM
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|
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| 5 |
IC50 = 8510 nM
|
|
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| 6 |
Ki = 0.035 nM
|
|
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| 7 |
Ki = 0.039 nM
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|
|
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CP0474393
|
N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]furan-3-carboxamide
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|
C39H51N11O7
|
1
|
| 1 |
EC50 = 0.11 nM
|
|
|
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CP0477053
|
N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]cyclohexanecarboxamide
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|
C41H59N11O6
|
1
|
| 1 |
EC50 = 0.12 nM
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|
|
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CP0474396
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(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-[3-(1H-indol-3-yl)propanoylamino]butanediamide
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|
C50H68N14O10
|
1
|
| 1 |
EC50 = 0.13 nM
|
|
|
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CP0477052
|
(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-4-methyl-2-[[[(2S)-3-phenyl-2-(propanoylamino)propanoyl]amino]carbamoylamino]pentanamide
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|
C37H53N11O6
|
1
|
| 1 |
EC50 = 0.13 nM
|
|
|
|
CP0533850
|
N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]pyridine-3-carboxamide
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|
C40H52N12O6
|
1
|
| 1 |
EC50 = 0.16 nM
|
|
|
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CP0575492
|
(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-(3-phenylpropanoylamino)butanediamide
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|
C48H67N13O10
|
1
|
| 1 |
EC50 = 0.17 nM
|
|
|
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CP0557278
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N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]-1H-pyrrole-2-carboxamide
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C39H52N12O6
|
1
|
| 1 |
EC50 = 0.23 nM
|
|
|
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CP0477055
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N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]-1H-imidazole-5-carboxamide
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|
C38H51N13O6
|
1
|
| 1 |
EC50 = 0.24 nM
|
|
|
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CP0083577
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(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-pyridin-4-ylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
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|
C56H76N16O12
|
5
|
| 1 |
EC50 = 0.27 nM
|
|
|
| 2 |
EC50 = 2.6 nM
|
|
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| 3 |
IC50 = 8.94 nM
|
|
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| 4 |
Ki = 0.089 nM
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|
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| 5 |
Ki = 0.11 nM
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CP0477054
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(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-4-methyl-2-[[[(2S)-3-phenyl-2-[(2-phenylacetyl)amino]propanoyl]amino]carbamoylamino]pentanamide
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|
C42H55N11O6
|
1
|
| 1 |
EC50 = 0.27 nM
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|
|
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CP0158503
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(2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-2-(2-methylpropyl)pent-3-enamide
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|
C42H52FN9O5
|
2
|
| 1 |
EC50 = 0.3 nM
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|
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| 2 |
IC50 = 0.12 nM
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CP0908452
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(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-(3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide
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|
C62H80N16O12
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2
|
| 1 |
EC50 = 0.3 nM
|
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| 2 |
Ki = 0.039 nM
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CP0920598
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(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-11-isobutyl-21-methyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide
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|
C63H83N17O11
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2
|
| 1 |
EC50 = 0.31 nM
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| 2 |
Ki = 0.028 nM
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CP0875171
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(S)-2-((R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)succinamide
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|
C64H83N17O13
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2
|
| 1 |
EC50 = 0.33 nM
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| 2 |
Ki = 0.036 nM
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CP0485519
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(2S)-2-[[[(2S)-2-acetamido-3-phenylpropanoyl]amino]carbamoylamino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-4-methylpentanamide
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|
C34H50N10O6
|
1
|
| 1 |
EC50 = 0.33 nM
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CP0158502
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(2R,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pentanamide
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|
C42H54FN9O6
|
2
|
| 1 |
EC50 = 0.36 nM
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| 2 |
IC50 = 0.24 nM
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CP0851167
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(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-benzamido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide
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C69H85N17O13
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2
|
| 1 |
EC50 = 0.44 nM
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| 2 |
Ki = 0.027 nM
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CP0868247
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(S)-2-((S)-2-((S)-4-amino-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-4-oxobutanamido)-3-(1H-indol-3-yl)propanamido)-N1-((6S,9S,15S,18S)-1-amino-6-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-15-benzyl-19-hydroxy-1-imino-9-isobutyl-8,11,14,17-tetraoxo-2,7,10,13,16-pentaazanonadecan-18-yl)succinamide
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C65H84N18O14
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2
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| 1 |
EC50 = 0.44 nM
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| 2 |
Ki = 0.026 nM
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CP0210913
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide
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|
C41H51FN10O6
|
3
|
| 1 |
EC50 = 0.45 nM
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| 2 |
EC50 = 0.69 nM
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| 3 |
IC50 = 0.71 nM
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CP0851170
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2-((2S,5S,8S,11R,14R)-11-((1H-indol-3-yl)methyl)-14-amino-2-benzyl-5-(hydroxymethyl)-15-(4-hydroxyphenyl)-8-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-(3-methylguanidino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)hydrazinecarboxamide
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C60H78N16O11
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1
|
| 1 |
EC50 = 0.49 nM
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CP0868245
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(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazahenicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide
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C61H79N17O12
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2
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| 1 |
EC50 = 0.51 nM
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| 2 |
Ki = 0.037 nM
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CP0865107
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(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-21-(1H-indol-3-yl)-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazahenicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide
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C66H82N18O11
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1
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| 1 |
EC50 = 0.59 nM
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CP0533851
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N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]benzamide
Show/Hide
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C39H52N10O6
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1
|
| 1 |
EC50 = 0.6 nM
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CP0578237
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(2S)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-[3-(1H-indol-3-yl)propanoylamino]-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide
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C43H57N11O6
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1
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| 1 |
EC50 = 0.62 nM
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CP0848309
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2-((2S,5S,8S,11R,14R)-11-((1H-indol-3-yl)methyl)-14-amino-2-benzyl-5-((R)-1-hydroxyethyl)-15-(4-hydroxyphenyl)-8-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-(3-methylguanidino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)hydrazinecarboxamide
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C61H80N16O11
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1
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| 1 |
EC50 = 0.63 nM
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CP0922198
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2-((2S,5S,8S,11R,14R)-11-((1H-indol-3-yl)methyl)-14-amino-2-benzyl-8-ethyl-5-(hydroxymethyl)-15-(4-hydroxyphenyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-(3-methylguanidino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)hydrazinecarboxamide
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C61H80N16O11
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2
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| 1 |
EC50 = 0.64 nM
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| 2 |
Ki = 0.12 nM
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CP0868246
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(2S)-2-({N'-[(2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-2-amino-3-(4-hydroxyphenyl)propanamido]-3-(pyridin-4-yl)propanamido]propanamido]-3-hydroxypropanamido]-3-phenylpropanoyl]hydrazinecarbonyl}amino)-N-[(1S)-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-(1-methylcarbamimidamido)butyl]-4-methylpentanamide
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C57H76N16O11
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2
|
| 1 |
EC50 = 0.7 nM
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| 2 |
Ki = 0.2 nM
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CP0913533
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(S)-2-((R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)succinamide
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C61H81N17O13
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2
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| 1 |
EC50 = 0.75 nM
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| 2 |
Ki = 0.089 nM
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CP0435595
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(pyridin-2-ylformamido)propanamido]acetamido}pentanamide
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C40H51N11O6
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1
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| 1 |
EC50 = 0.8 nM
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CP0871691
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(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-butyramido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide
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C66H87N17O13
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1
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| 1 |
EC50 = 0.8 nM
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CP0908491
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(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-(cyclopropanecarboxamido)-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide
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C66H85N17O13
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2
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| 1 |
EC50 = 0.82 nM
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| 2 |
Ki = 0.034 nM
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CP0858417
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(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazahenicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide
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C58H77N17O12
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2
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| 1 |
EC50 = 0.87 nM
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| 2 |
Ki = 0.074 nM
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CP0557279
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(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-(benzylamino)-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide
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C41H55N11O5
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1
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| 1 |
EC50 = 0.89 nM
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CP0908453
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(S)-2-((R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)succinamide
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C62H82N16O13
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2
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| 1 |
EC50 = 0.94 nM
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| 2 |
Ki = 0.038 nM
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CP0445746
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-{[4-(acetamidomethyl)phenyl]formamido}-3-phenylpropanamido]acetamido}-4-methylpentanamide
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C44H57N11O7
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1
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| 1 |
EC50 = 0.99 nM
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CP0463211
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(phenylformamido)propanamido]acetamido}pentanamide
Show/Hide
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C41H52N10O6
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1
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| 1 |
EC50 = 0.99 nM
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CP0898490
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-2-[(4-nitrophenyl)formamido]-3-phenylpropanamido]acetamido}pentanamide
Show/Hide
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C41H51N11O8
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1
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| 1 |
EC50 = 1 nM
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CP0848308
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(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide
Show/Hide
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C62H81N17O12
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2
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| 1 |
EC50 = 1 nM
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| 2 |
Ki = 0.036 nM
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CP0399987
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(3-hydroxyphenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide
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C41H52N10O7
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1
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| 1 |
EC50 = 1.2 nM
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CP0524534
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-methoxyphenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide
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C42H54N10O7
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1
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| 1 |
EC50 = 1.2 nM
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CP0865108
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(S)-1-((S)-4-amino-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)-4-oxobutanoyl)-N-((8S,11S,17S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-3-imino-11-isobutyl-10,13,16-trioxo-18-phenyl-2,4,9,12,14,15-hexaazaoctadecan-17-yl)pyrrolidine-2-carboxamide
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C60H79N17O11
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2
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| 1 |
EC50 = 1.2 nM
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| 2 |
Ki = 0.096 nM
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CP0445744
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-chlorophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide
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C41H51ClN10O6
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1
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| 1 |
EC50 = 1.3 nM
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CP0907777
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2-((2S,5S,8S,11R,14R)-14-amino-2-benzyl-8-((R)-1-hydroxyethyl)-5-(hydroxymethyl)-15-(4-hydroxyphenyl)-4,7,10,13-tetraoxo-11-(pyridin-4-ylmethyl)-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-(3-methylguanidino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)hydrazinecarboxamide
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C58H78N16O12
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1
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| 1 |
EC50 = 1.3 nM
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CP0406559
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-{[4-(carbamimidamidomethyl)phenyl]formamido}-3-phenylpropanamido]acetamido}-4-methylpentanamide
Show/Hide
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C43H57N13O6
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1
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| 1 |
EC50 = 1.4 nM
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CP0438591
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(2S)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-(hexanoylamino)-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide
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C38H58N10O6
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1
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| 1 |
EC50 = 1.4 nM
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CP0922192
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(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-11-isobutyl-21,21-dimethyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide
Show/Hide
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C61H83N17O11
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1
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| 1 |
EC50 = 1.5 nM
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CP0474395
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(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-(3-pyridin-4-ylpropanoylamino)butanediamide
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C47H66N14O10
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1
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| 1 |
EC50 = 1.5 nM
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CP0457949
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(2S)-2-{2-[(2S)-2-[(4-aminophenyl)formamido]-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide
Show/Hide
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C41H53N11O6
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1
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| 1 |
EC50 = 1.6 nM
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CP0922184
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(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide
Show/Hide
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C59H79N17O12
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2
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| 1 |
EC50 = 1.6 nM
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| 2 |
Ki = 0.086 nM
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CP0406555
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(pyridin-4-ylformamido)propanamido]acetamido}pentanamide
Show/Hide
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C40H51N11O6
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1
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| 1 |
EC50 = 1.7 nM
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CP0435594
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-(1H-imidazol-4-ylformamido)-3-phenylpropanamido]acetamido}-4-methylpentanamide
Show/Hide
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C38H50N12O6
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1
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| 1 |
EC50 = 1.7 nM
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CP0445749
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-carbamimidamidophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide
Show/Hide
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C42H55N13O6
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1
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| 1 |
EC50 = 1.7 nM
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CP0858419
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(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-11-isobutyl-21-methyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide
Show/Hide
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C60H81N17O11
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2
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| 1 |
EC50 = 1.8 nM
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| 2 |
Ki = 0.052 nM
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CP0445747
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(1H-pyrrol-2-ylformamido)propanamido]acetamido}pentanamide
Show/Hide
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C39H51N11O6
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1
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| 1 |
EC50 = 2 nM
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CP0463212
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-hydroxyphenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide
Show/Hide
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C41H52N10O7
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1
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| 1 |
EC50 = 2.1 nM
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CP0575493
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(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
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C52H71N15O11
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1
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| 1 |
EC50 = 2.1 nM
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CP0270121
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{3-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]propyl}-4-methylpentanamide
Show/Hide
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C42H54FN9O5
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2
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| 1 |
EC50 = 2.5 nM
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| 2 |
IC50 = 1.2 nM
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CP0445750
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-[(4-{[(pyridin-2-ylmethyl)amino]methyl}phenyl)formamido]propanamido]acetamido}pentanamide
Show/Hide
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C48H60N12O6
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1
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| 1 |
EC50 = 2.7 nM
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CP0850851
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(2S)-1-((S)-4-amino-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)-4-oxobutanoyl)-N-((8S,11S,17S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-3-imino-11-isobutyl-10,13,16-trioxo-18-phenyl-2,4,9,12,14,15-hexaazaoctadecan-17-yl)-4-hydroxypyrrolidine-2-carboxamide
Show/Hide
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C60H79N17O12
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1
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| 1 |
EC50 = 2.8 nM
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CP0406554
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2-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}phenyl 2-hydroxybenzoate
Show/Hide
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C48H56N10O9
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1
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| 1 |
EC50 = 3 nM
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CP0427902
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(pyridin-3-ylformamido)propanamido]acetamido}pentanamide
Show/Hide
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C40H51N11O6
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1
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| 1 |
EC50 = 3 nM
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CP0505374
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-{[4-(hydroxymethyl)phenyl]formamido}-3-phenylpropanamido]acetamido}-4-methylpentanamide
Show/Hide
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C42H54N10O7
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1
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| 1 |
EC50 = 3 nM
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CP0406558
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(2S)-2-{2-[(2S)-2-{[4-(aminomethyl)phenyl]formamido}-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide
Show/Hide
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C42H55N11O6
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1
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| 1 |
EC50 = 3.1 nM
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CP0475215
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(2S)-2-{2-[(2S)-2-[(2-aminophenyl)formamido]-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide
Show/Hide
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C41H53N11O6
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1
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| 1 |
EC50 = 3.1 nM
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CP0406552
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(2S)-2-{2-[(2S)-2-[(4-{[bis(pyridin-2-ylmethyl)amino]methyl}phenyl)formamido]-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide
Show/Hide
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C54H65N13O6
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1
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| 1 |
EC50 = 3.3 nM
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CP0406557
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(2S)-2-{2-[(2S)-2-({4-[(benzylamino)methyl]phenyl}formamido)-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide
Show/Hide
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C49H61N11O6
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1
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| 1 |
EC50 = 3.3 nM
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CP0158366
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(2R,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pentanamide
Show/Hide
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C42H54FN9O6
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2
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| 1 |
EC50 = 4.3 nM
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| 2 |
IC50 = 5.7 nM
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CP0848307
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(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-11-isobutyl-10,13,16,19-tetraoxo-20-phenyl-2,4,9,12,14,15,18-heptaazaicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide
Show/Hide
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C63H79N17O11
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1
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| 1 |
EC50 = 4.4 nM
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CP0406556
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(2S)-2-{2-[(2S)-2-[(3-aminophenyl)formamido]-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide
Show/Hide
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C41H53N11O6
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1
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| 1 |
EC50 = 4.7 nM
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CP0445745
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(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(2-hydroxyphenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide
Show/Hide
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C41H52N10O7
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1
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| 1 |
EC50 = 5 nM
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CP0267258
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(2E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-2-(2-methylpropyl)pent-2-enamide
Show/Hide
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C42H52FN9O5
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2
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| 1 |
EC50 = 5.4 nM
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| 2 |
IC50 = 4.6 nM
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CP0477082
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(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
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C50H69N15O10
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1
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| 1 |
EC50 = 7.7 nM
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CP0575491
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(2S)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-[[(2S)-3-hydroxy-2-[3-(1H-indol-3-yl)propanoylamino]propanoyl]amino]-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide
Show/Hide
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C46H62N12O8
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1
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| 1 |
EC50 = 8.2 nM
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|
CP0520456
|
(2S)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-amino-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide
Show/Hide
|
C32H48N10O5
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0406553
|
(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-2-[(2,3,4,5,6-pentafluorophenyl)formamido]-3-phenylpropanamido]acetamido}pentanamide
Show/Hide
|
C41H47F5N10O6
|
1
|
| 1 |
EC50 > 100 nM
|
|
|
|
CP0475214
|
(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-[(3,4,5-trihydroxyphenyl)formamido]propanamido]acetamido}pentanamide
Show/Hide
|
C41H52N10O9
|
1
|
| 1 |
EC50 > 100 nM
|
|
|
|
CP0487760
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-piperazin-1-ylphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C27H22FN5O3
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0454298
|
N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C26H20FN5O4
|
2
|
| 1 |
IC50 = 3.7 nM
|
|
|
| 2 |
IC50 = 460 nM
|
|
|
|
CP0438744
|
N-[4-[3-[(2-aminoacetyl)amino]phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C25H18FN5O4
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0373020
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[3-(methylamino)propanoylamino]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C27H22FN5O4
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0514912
|
N-[3-cyano-4-[3-(1,4-diazepan-1-yl)phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C28H24FN5O3
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0446441
|
N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C26H20FN5O3S
|
2
|
| 1 |
IC50 = 7.4 nM
|
|
|
| 2 |
IC50 = 3600 nM
|
|
|
|
CP0487759
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[[2-[(2S)-pyrrolidin-2-yl]acetyl]amino]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H24FN5O4
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0446442
|
N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C26H20FN5O4
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 660 nM
|
|
|
|
CP0448306
|
N-[3-cyano-4-[3-[3-(ethylamino)pentanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C30H28FN5O4
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0430721
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[[2-(methylamino)acetyl]amino]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C26H20FN5O4
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0180522
|
(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C63H84N18O14
|
2
|
| 1 |
IC50 = 9.67 nM
|
|
|
| 2 |
Ki = 0.051 nM
|
|
|
|
CP0491036
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[3-(propan-2-ylamino)butanoylamino]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C30H28FN5O4
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0931001
|
N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(piperazin-1-ylmethyl)phenyl]pyridin-2-yl}furan-2-carbox-amide trifluoroacetate
Show/Hide
|
C30H25F4N5O5
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
|
CP0388158
|
N-[4-[3-(3-aminopropanoylamino)phenyl]-6-(4-chloro-2-hydroxyphenyl)-3-cyanopyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C26H20ClN5O3S
|
2
|
| 1 |
IC50 = 9.8 nM
|
|
|
| 2 |
IC50 = 4100 nM
|
|
|
|
CP0448305
|
N-[3-cyano-4-[3-[3-(ethylamino)butanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H26FN5O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0487758
|
N-[3-cyano-4-[3-[3-(dimethylamino)propanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C28H24FN5O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0504184
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[[2-[(2R)-pyrrolidin-2-yl]acetyl]amino]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H24FN5O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0504282
|
N-[3-cyano-4-[3-[3-[ethyl(methyl)amino]propanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H26FN5O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0505819
|
N-[4-[3-[(3-amino-2,2-dimethylpropyl)carbamoyl]phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H26FN5O4
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 2500 nM
|
|
|
|
CP0520918
|
N-[3-cyano-4-[3-(4-ethylpiperazin-1-yl)phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H26FN5O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0472475
|
N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxy-4-methylphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C27H23N5O3S
|
2
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 910 nM
|
|
|
|
CP0438701
|
N-[3-cyano-4-[3-[[2-(dimethylamino)acetyl]amino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C27H22FN5O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0446437
|
N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C26H21N5O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0504243
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[(2-piperidin-2-ylacetyl)amino]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C30H26FN5O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0487863
|
N-[4-[3-[(1-amino-2-methylpropan-2-yl)carbamoyl]phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C28H25N5O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0516512
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(4-methylpiperazin-1-yl)phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C28H24FN5O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0543066
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[(2-piperidin-1-ylacetyl)amino]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C30H26FN5O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0491035
|
N-[3-cyano-4-[3-[3-(diethylamino)propanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C30H28FN5O4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0509612
|
(2R)-N-[3-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-2-(furan-2-carbonylamino)pyridin-4-yl]phenyl]pyrrolidine-2-carboxamide
Show/Hide
|
C28H22FN5O4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0400806
|
N-[3-cyano-4-[3-[3-(diethylamino)butanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C31H30FN5O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0487756
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[[2-[(2S)-1-methylpyrrolidin-2-yl]acetyl]amino]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C30H26FN5O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0504244
|
N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H26FN5O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0543054
|
N-[3-cyano-4-[3-[3-(dimethylamino)butanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H26FN5O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0225128
|
(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C60H82N18O14
|
2
|
| 1 |
IC50 = 18.3 nM
|
|
|
| 2 |
Ki = 0.12 nM
|
|
|
|
CP0472474
|
N-[4-[3-(3-aminopropanoylamino)phenyl]-6-(4-bromo-2-hydroxyphenyl)-3-cyanopyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C26H20BrN5O3S
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
IC50 = 6300 nM
|
|
|
|
CP0471032
|
N-[3-cyano-4-[3-[(4-ethylpiperazin-1-yl)methyl]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C30H28FN5O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0943905
|
N-[3-Cyano-4-(3-{[2-(dimethylamino)ethyl]carbamoyl}phenyl)-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide hydrochloride
Show/Hide
|
C28H25ClFN5O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0446434
|
N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C26H21N5O3S
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0504183
|
N-[3-cyano-4-[3-[3-(diethylamino)pentanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C32H32FN5O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0912126
|
N-{3-Cyano-4-[3-(1,4-diazepan-1-ylmethyl)phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl}furan-2-carboxamide dihydrochloride
Show/Hide
|
C29H28Cl2FN5O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0388164
|
N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C26H21N5O3S
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 5100 nM
|
|
|
|
CP0471031
|
N-[3-cyano-4-[3-[2-(dimethylamino)ethyl-methylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C28H26FN5O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0487757
|
N-[3-cyano-4-[3-[2-(ethylamino)butanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
Show/Hide
|
C29H26FN5O4
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0388160
|
N-(2-aminoethyl)-3-[3-cyano-6-(2-hydroxyphenyl)-2-[(4-methoxybenzoyl)amino]pyridin-4-yl]benzamide
Show/Hide
|
C29H25N5O4
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0123124
|
(2S,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pentanamide
Show/Hide
|
C42H54FN9O6
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0166625
|
(2E,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pent-2-enamide
Show/Hide
|
C42H52FN9O6
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0388161
|
N-[4-[3-[(1-amino-2-methylpropan-2-yl)carbamoyl]phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]-2-methoxybenzamide
Show/Hide
|
C31H29N5O4
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0506194
|
N-(1-amino-2-methylpropan-2-yl)-3-[3-cyano-6-(2-hydroxyphenyl)-2-[(4-methoxybenzoyl)amino]pyridin-4-yl]benzamide
Show/Hide
|
C31H29N5O4
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0446438
|
N-[4-[3-(4-aminobutanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C27H23N5O3S
|
2
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
IC50 = 1400 nM
|
|
|
|
CP0334235
|
(2R)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C60H82N18O14
|
2
|
| 1 |
IC50 = 41.2 nM
|
|
|
| 2 |
Ki = 0.11 nM
|
|
|
|
CP0388159
|
N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]-2-methoxybenzamide
Show/Hide
|
C29H25N5O4
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0388163
|
N-[4-[3-[(2-aminoacetyl)amino]phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C25H19N5O3S
|
2
|
| 1 |
IC50 = 51 nM
|
|
|
| 2 |
IC50 = 2800 nM
|
|
|
|
CP0520842
|
N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]benzamide
Show/Hide
|
C28H23N5O3
|
2
|
| 1 |
IC50 = 51 nM
|
|
|
| 2 |
IC50 = 24000 nM
|
|
|
|
CP0083575
|
(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C64H85N17O14
|
2
|
| 1 |
IC50 = 87 nM
|
|
|
| 2 |
Ki = 0.046 nM
|
|
|
|
CP0504405
|
N-[4-[4-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C26H21N5O3S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0506196
|
N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxy-4-methoxyphenyl)pyridin-2-yl]benzamide
Show/Hide
|
C29H25N5O4
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0460356
|
N-[3-cyano-4-[3-[[2-(dimethylamino)acetyl]amino]phenyl]-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
|
C27H23N5O3S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0270119
|
(2R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide
Show/Hide
|
C41H51FN10O6
|
1
|
| 1 |
IC50 = 240 nM
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CP0123122
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(2S,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pentanamide
Show/Hide
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C42H54FN9O6
|
1
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| 1 |
IC50 = 380 nM
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|
|
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CP0137856
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(2E,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pent-2-enamide
Show/Hide
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C42H52FN9O6
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1
|
| 1 |
IC50 = 460 nM
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|
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CP0506195
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N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxy-5-methoxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
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C27H23N5O4S
|
1
|
| 1 |
IC50 = 480 nM
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|
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CP0446440
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N-[4-[3-(3-aminopropanoylamino)phenyl]-6-(5-chloro-2-hydroxyphenyl)-3-cyanopyridin-2-yl]thiophene-2-carboxamide
Show/Hide
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C26H20ClN5O3S
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1
|
| 1 |
IC50 = 490 nM
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|
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CP0446433
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N-[4-[3-(aminomethyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
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C24H18N4O2S
|
1
|
| 1 |
IC50 = 570 nM
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|
|
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CP0388165
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N-[6-(2-aminophenyl)-4-[3-(3-aminopropanoylamino)phenyl]-3-cyanopyridin-2-yl]benzamide
Show/Hide
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C28H24N6O2
|
1
|
| 1 |
IC50 = 890 nM
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|
|
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CP0504406
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N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)-5-methylpyridin-2-yl]furan-2-carboxamide
Show/Hide
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C27H23N5O4
|
1
|
| 1 |
IC50 = 1200 nM
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|
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CP0506193
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N-[3-cyano-4-[3-(hydroxymethyl)phenyl]-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
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C24H17N3O3S
|
1
|
| 1 |
IC50 = 1500 nM
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|
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CP0388162
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N-[4-(3-aminophenyl)-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
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C23H16N4O2S
|
1
|
| 1 |
IC50 = 2100 nM
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|
|
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CP0520841
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3-{3-Cyano-6-(2-hydroxyphenyl)-2-[(thiophen-2-ylcarbonyl)amino]pyridin-4-yl}benzoic acid
Show/Hide
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C24H15N3O4S
|
1
|
| 1 |
IC50 = 9900 nM
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|
|
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CP0446436
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N-[4-(3-aminophenyl)-3-cyano-6-(2-methoxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
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C24H18N4O2S
|
1
|
| 1 |
IC50 > 30000 nM
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|
|
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CP0446435
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N-[4-[2-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
Show/Hide
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C26H21N5O3S
|
1
|
| 1 |
IC50 = 33000 nM
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|
|
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CP0366655
|
(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
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C61H79N15O12
|
1
|
| 1 |
Ki = 0.032 nM
|
|
|
|
CP0523493
|
(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
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C65H85N19O13
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1
|
| 1 |
Ki = 0.033 nM
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|
|
|
CP0366656
|
(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
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C62H82N18O14
|
1
|
| 1 |
Ki = 0.045 nM
|
|
|
|
CP0339422
|
(2R)-N-[(2R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
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C63H84N18O14
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1
|
| 1 |
Ki = 0.052 nM
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|
|
|
CP0367957
|
(2S)-2-[[(2S)-2-[[(2R)-4-amino-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoyl]amino]-3-cyclohexylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
|
C61H89N17O14
|
1
|
| 1 |
Ki = 0.055 nM
|
|
|
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CP0350370
|
(2R)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C63H84N18O14
|
1
|
| 1 |
Ki = 0.062 nM
|
|
|
|
CP0071237
|
(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
|
C59H78N16O12
|
1
|
| 1 |
Ki = 0.065 nM
|
|
|
|
CP0260603
|
(2S)-N-[(2R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C63H84N18O14
|
1
|
| 1 |
Ki = 0.078 nM
|
|
|
|
CP0150085
|
(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
|
C57H77N15O12
|
1
|
| 1 |
Ki = 0.086 nM
|
|
|
|
CP0366654
|
(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
|
C62H83N17O14
|
1
|
| 1 |
Ki = 0.086 nM
|
|
|
|
CP0258966
|
(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2R)-2-amino-3-pyridin-3-ylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]butanediamide
Show/Hide
|
C58H77N17O11
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0071236
|
(2S)-2-[[(2S,3S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
|
C54H79N15O12
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0247747
|
(2S)-N-[(2R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C60H82N18O14
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0258965
|
(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-pyridin-3-ylpropanoyl]amino]butanediamide
Show/Hide
|
C62H83N19O13
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0366653
|
(2R)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C61H83N17O14
|
1
|
| 1 |
Ki = 0.12 nM
|
|
|
|
CP0258832
|
(2S)-2-[[(2S,3R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
|
C52H75N15O13
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0258833
|
(2S)-2-[[(2S)-2-[[(2R)-4-amino-2-[[(2R)-2-amino-3-pyridin-3-ylpropanoyl]amino]-4-oxobutanoyl]amino]-3-cyclohexylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
|
C60H88N18O13
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0336463
|
(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2R)-2-amino-3-pyridin-3-ylpropanoyl]amino]-3-phenylpropanoyl]amino]butanediamide
Show/Hide
|
C56H76N16O11
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0134996
|
(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide
Show/Hide
|
C51H73N15O13
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
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CP0334234
|
(2R)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
|
C60H82N18O14
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0105322
|
(2R)-N-[(2S,3R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide
Show/Hide
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C56H81N17O15
|
1
|
| 1 |
Ki = 0.29 nM
|
|
|
|
CP0242406
|
(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-aminopropanoyl]amino]butanediamide
Show/Hide
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C57H80N18O13
|
1
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| 1 |
Ki = 0.51 nM
|
|
|
