Protein Information

General Information of the Protein

Protein ID	PT02017
Protein Name	KiSS-1 receptor
Secondarily Protein Name	G-protein coupled receptor 54 G-protein coupled receptor OT7T175 Hypogonadotropin-1 Kisspeptins receptor Metastin receptor
Gene Name	KISS1R
Secondarily Gene Name	AXOR12 GPR54
Sequence	MHTVATSGPNASWGAPANASGCPGCGANASDGPVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSPGPRAYCSEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRVCPCAPRRPRRPRRPGPSDPAAPHAELLRLGSHPAPARAQKPGSSGLAARGLCVLGEDNAPL Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor > Family A G protein-coupled receptor > Peptide receptor (family A GPCR) > Short peptide receptor (family A GPCR) > RF amide receptor
Function	Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins. Show/Hide
Uniprot ID	Primary ID: Q969F8 Secondarily ID: A5D8U2 B2RTV1 Q96QG0 Show/Hide
Ensembl ID	ENSG00000116014
HGNC ID	HGNC:4510
Subcellular Location	Cell membrane

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000011 , CHO

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0567389 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-[3-(1H-indol-3-yl)propanoylamino]-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide Show/Hide	C45H58N12O6	1
1	EC50 = 0.022 nM Bioactivity Info	TI LI LO TS
CP0474394 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]benzamide Show/Hide	C41H53N11O6	1
1	EC50 = 0.024 nM Bioactivity Info	TI LI LO TS
CP0571054 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]cyclopropanecarboxamide Show/Hide	C38H53N11O6	1
1	EC50 = 0.028 nM Bioactivity Info	TI LI LO TS
CP0438590 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]pyridine-2-carboxamide Show/Hide	C40H52N12O6	1
1	EC50 = 0.037 nM Bioactivity Info	TI LI LO TS
CP0367958 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C59H78N16O12	2
1	EC50 = 0.057 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.044 nM Bioactivity Info	TI LI LO TS
CP0534680 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-4-methyl-2-[[[(2S)-2-(2-methylpropanoylamino)-3-phenylpropanoyl]amino]carbamoylamino]pentanamide Show/Hide	C38H55N11O6	1
1	EC50 = 0.058 nM Bioactivity Info	TI LI LO TS
CP0352243 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]pyridine-4-carboxamide Show/Hide	C40H52N12O6	1
1	EC50 = 0.068 nM Bioactivity Info	TI LI LO TS
CP0039237 Compound Info	(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]butanediamido]-3-(1H-indol-3-yl)propanamido]-N-[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]butanediamide Show/Hide	C63H83N17O14	7
1	EC50 = 0.087 nM Bioactivity Info	TI LI LO TS
2	EC50 = 0.24 nM Bioactivity Info	TI LI LO TS
3	EC50 = 0.96 nM Bioactivity Info	TI LI LO TS
4	IC50 = 0.07 nM Bioactivity Info	TI LI LO TS
5	IC50 = 8510 nM Bioactivity Info	TI LI LO TS
6	Ki = 0.035 nM Bioactivity Info	TI LI LO TS
7	Ki = 0.039 nM Bioactivity Info	TI LI LO TS
CP0474393 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]furan-3-carboxamide Show/Hide	C39H51N11O7	1
1	EC50 = 0.11 nM Bioactivity Info	TI LI LO TS
CP0477053 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]cyclohexanecarboxamide Show/Hide	C41H59N11O6	1
1	EC50 = 0.12 nM Bioactivity Info	TI LI LO TS
CP0474396 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-[3-(1H-indol-3-yl)propanoylamino]butanediamide Show/Hide	C50H68N14O10	1
1	EC50 = 0.13 nM Bioactivity Info	TI LI LO TS
CP0477052 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-4-methyl-2-[[[(2S)-3-phenyl-2-(propanoylamino)propanoyl]amino]carbamoylamino]pentanamide Show/Hide	C37H53N11O6	1
1	EC50 = 0.13 nM Bioactivity Info	TI LI LO TS
CP0533850 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]pyridine-3-carboxamide Show/Hide	C40H52N12O6	1
1	EC50 = 0.16 nM Bioactivity Info	TI LI LO TS
CP0575492 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-(3-phenylpropanoylamino)butanediamide Show/Hide	C48H67N13O10	1
1	EC50 = 0.17 nM Bioactivity Info	TI LI LO TS
CP0557278 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]-1H-pyrrole-2-carboxamide Show/Hide	C39H52N12O6	1
1	EC50 = 0.23 nM Bioactivity Info	TI LI LO TS
CP0477055 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]-1H-imidazole-5-carboxamide Show/Hide	C38H51N13O6	1
1	EC50 = 0.24 nM Bioactivity Info	TI LI LO TS
CP0083577 Compound Info	(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-pyridin-4-ylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C56H76N16O12	5
1	EC50 = 0.27 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2.6 nM Bioactivity Info	TI LI LO TS
3	IC50 = 8.94 nM Bioactivity Info	TI LI LO TS
4	Ki = 0.089 nM Bioactivity Info	TI LI LO TS
5	Ki = 0.11 nM Bioactivity Info	TI LI LO TS
CP0477054 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-4-methyl-2-[[[(2S)-3-phenyl-2-[(2-phenylacetyl)amino]propanoyl]amino]carbamoylamino]pentanamide Show/Hide	C42H55N11O6	1
1	EC50 = 0.27 nM Bioactivity Info	TI LI LO TS
CP0158503 Compound Info	(2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-2-(2-methylpropyl)pent-3-enamide Show/Hide	C42H52FN9O5	2
1	EC50 = 0.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.12 nM Bioactivity Info	TI LI LO TS
CP0908452 Compound Info	(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-(3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide Show/Hide	C62H80N16O12	2
1	EC50 = 0.3 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.039 nM Bioactivity Info	TI LI LO TS
CP0920598 Compound Info	(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-11-isobutyl-21-methyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide Show/Hide	C63H83N17O11	2
1	EC50 = 0.31 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.028 nM Bioactivity Info	TI LI LO TS
CP0875171 Compound Info	(S)-2-((R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)succinamide Show/Hide	C64H83N17O13	2
1	EC50 = 0.33 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.036 nM Bioactivity Info	TI LI LO TS
CP0485519 Compound Info	(2S)-2-[[[(2S)-2-acetamido-3-phenylpropanoyl]amino]carbamoylamino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-4-methylpentanamide Show/Hide	C34H50N10O6	1
1	EC50 = 0.33 nM Bioactivity Info	TI LI LO TS
CP0158502 Compound Info	(2R,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pentanamide Show/Hide	C42H54FN9O6	2
1	EC50 = 0.36 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.24 nM Bioactivity Info	TI LI LO TS
CP0851167 Compound Info	(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-benzamido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide Show/Hide	C69H85N17O13	2
1	EC50 = 0.44 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.027 nM Bioactivity Info	TI LI LO TS
CP0868247 Compound Info	(S)-2-((S)-2-((S)-4-amino-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-4-oxobutanamido)-3-(1H-indol-3-yl)propanamido)-N1-((6S,9S,15S,18S)-1-amino-6-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-15-benzyl-19-hydroxy-1-imino-9-isobutyl-8,11,14,17-tetraoxo-2,7,10,13,16-pentaazanonadecan-18-yl)succinamide Show/Hide	C65H84N18O14	2
1	EC50 = 0.44 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.026 nM Bioactivity Info	TI LI LO TS
CP0210913 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C41H51FN10O6	3
1	EC50 = 0.45 nM Bioactivity Info	TI LI LO TS
2	EC50 = 0.69 nM Bioactivity Info	TI LI LO TS
3	IC50 = 0.71 nM Bioactivity Info	TI LI LO TS
CP0851170 Compound Info	2-((2S,5S,8S,11R,14R)-11-((1H-indol-3-yl)methyl)-14-amino-2-benzyl-5-(hydroxymethyl)-15-(4-hydroxyphenyl)-8-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-(3-methylguanidino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)hydrazinecarboxamide Show/Hide	C60H78N16O11	1
1	EC50 = 0.49 nM Bioactivity Info	TI LI LO TS
CP0868245 Compound Info	(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazahenicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide Show/Hide	C61H79N17O12	2
1	EC50 = 0.51 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.037 nM Bioactivity Info	TI LI LO TS
CP0865107 Compound Info	(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-21-(1H-indol-3-yl)-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazahenicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide Show/Hide	C66H82N18O11	1
1	EC50 = 0.59 nM Bioactivity Info	TI LI LO TS
CP0533851 Compound Info	N-[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]benzamide Show/Hide	C39H52N10O6	1
1	EC50 = 0.6 nM Bioactivity Info	TI LI LO TS
CP0578237 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-[3-(1H-indol-3-yl)propanoylamino]-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide Show/Hide	C43H57N11O6	1
1	EC50 = 0.62 nM Bioactivity Info	TI LI LO TS
CP0848309 Compound Info	2-((2S,5S,8S,11R,14R)-11-((1H-indol-3-yl)methyl)-14-amino-2-benzyl-5-((R)-1-hydroxyethyl)-15-(4-hydroxyphenyl)-8-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-(3-methylguanidino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)hydrazinecarboxamide Show/Hide	C61H80N16O11	1
1	EC50 = 0.63 nM Bioactivity Info	TI LI LO TS
CP0922198 Compound Info	2-((2S,5S,8S,11R,14R)-11-((1H-indol-3-yl)methyl)-14-amino-2-benzyl-8-ethyl-5-(hydroxymethyl)-15-(4-hydroxyphenyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-(3-methylguanidino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)hydrazinecarboxamide Show/Hide	C61H80N16O11	2
1	EC50 = 0.64 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0868246 Compound Info	(2S)-2-({N'-[(2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-[(2R)-2-amino-3-(4-hydroxyphenyl)propanamido]-3-(pyridin-4-yl)propanamido]propanamido]-3-hydroxypropanamido]-3-phenylpropanoyl]hydrazinecarbonyl}amino)-N-[(1S)-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-(1-methylcarbamimidamido)butyl]-4-methylpentanamide Show/Hide	C57H76N16O11	2
1	EC50 = 0.7 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.2 nM Bioactivity Info	TI LI LO TS
CP0913533 Compound Info	(S)-2-((R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)succinamide Show/Hide	C61H81N17O13	2
1	EC50 = 0.75 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.089 nM Bioactivity Info	TI LI LO TS
CP0435595 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(pyridin-2-ylformamido)propanamido]acetamido}pentanamide Show/Hide	C40H51N11O6	1
1	EC50 = 0.8 nM Bioactivity Info	TI LI LO TS
CP0871691 Compound Info	(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-butyramido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide Show/Hide	C66H87N17O13	1
1	EC50 = 0.8 nM Bioactivity Info	TI LI LO TS
CP0908491 Compound Info	(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-(cyclopropanecarboxamido)-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide Show/Hide	C66H85N17O13	2
1	EC50 = 0.82 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.034 nM Bioactivity Info	TI LI LO TS
CP0858417 Compound Info	(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazahenicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide Show/Hide	C58H77N17O12	2
1	EC50 = 0.87 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.074 nM Bioactivity Info	TI LI LO TS
CP0557279 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-(benzylamino)-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide Show/Hide	C41H55N11O5	1
1	EC50 = 0.89 nM Bioactivity Info	TI LI LO TS
CP0908453 Compound Info	(S)-2-((R)-2-((R)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)succinamide Show/Hide	C62H82N16O13	2
1	EC50 = 0.94 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.038 nM Bioactivity Info	TI LI LO TS
CP0445746 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-{[4-(acetamidomethyl)phenyl]formamido}-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C44H57N11O7	1
1	EC50 = 0.99 nM Bioactivity Info	TI LI LO TS
CP0463211 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(phenylformamido)propanamido]acetamido}pentanamide Show/Hide	C41H52N10O6	1
1	EC50 = 0.99 nM Bioactivity Info	TI LI LO TS
CP0898490 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-2-[(4-nitrophenyl)formamido]-3-phenylpropanamido]acetamido}pentanamide Show/Hide	C41H51N11O8	1
1	EC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0848308 Compound Info	(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)succinamide Show/Hide	C62H81N17O12	2
1	EC50 = 1 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.036 nM Bioactivity Info	TI LI LO TS
CP0399987 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(3-hydroxyphenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C41H52N10O7	1
1	EC50 = 1.2 nM Bioactivity Info	TI LI LO TS
CP0524534 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-methoxyphenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C42H54N10O7	1
1	EC50 = 1.2 nM Bioactivity Info	TI LI LO TS
CP0865108 Compound Info	(S)-1-((S)-4-amino-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)-4-oxobutanoyl)-N-((8S,11S,17S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-3-imino-11-isobutyl-10,13,16-trioxo-18-phenyl-2,4,9,12,14,15-hexaazaoctadecan-17-yl)pyrrolidine-2-carboxamide Show/Hide	C60H79N17O11	2
1	EC50 = 1.2 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.096 nM Bioactivity Info	TI LI LO TS
CP0445744 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-chlorophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C41H51ClN10O6	1
1	EC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0907777 Compound Info	2-((2S,5S,8S,11R,14R)-14-amino-2-benzyl-8-((R)-1-hydroxyethyl)-5-(hydroxymethyl)-15-(4-hydroxyphenyl)-4,7,10,13-tetraoxo-11-(pyridin-4-ylmethyl)-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-5-(3-methylguanidino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)hydrazinecarboxamide Show/Hide	C58H78N16O12	1
1	EC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0406559 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-{[4-(carbamimidamidomethyl)phenyl]formamido}-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C43H57N13O6	1
1	EC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0438591 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-(hexanoylamino)-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide Show/Hide	C38H58N10O6	1
1	EC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0922192 Compound Info	(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-11-isobutyl-21,21-dimethyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide Show/Hide	C61H83N17O11	1
1	EC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0474395 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-(3-pyridin-4-ylpropanoylamino)butanediamide Show/Hide	C47H66N14O10	1
1	EC50 = 1.5 nM Bioactivity Info	TI LI LO TS
CP0457949 Compound Info	(2S)-2-{2-[(2S)-2-[(4-aminophenyl)formamido]-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide Show/Hide	C41H53N11O6	1
1	EC50 = 1.6 nM Bioactivity Info	TI LI LO TS
CP0922184 Compound Info	(S)-N1-((8S,11S,17S,20S,21R)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide Show/Hide	C59H79N17O12	2
1	EC50 = 1.6 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.086 nM Bioactivity Info	TI LI LO TS
CP0406555 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(pyridin-4-ylformamido)propanamido]acetamido}pentanamide Show/Hide	C40H51N11O6	1
1	EC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0435594 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-(1H-imidazol-4-ylformamido)-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C38H50N12O6	1
1	EC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0445749 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-carbamimidamidophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C42H55N13O6	1
1	EC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0858419 Compound Info	(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-11-isobutyl-21-methyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazadocosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide Show/Hide	C60H81N17O11	2
1	EC50 = 1.8 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.052 nM Bioactivity Info	TI LI LO TS
CP0445747 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(1H-pyrrol-2-ylformamido)propanamido]acetamido}pentanamide Show/Hide	C39H51N11O6	1
1	EC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0463212 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-hydroxyphenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C41H52N10O7	1
1	EC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0575493 Compound Info	(2S)-2-[[(2S)-2-acetamido-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C52H71N15O11	1
1	EC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0270121 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{3-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]propyl}-4-methylpentanamide Show/Hide	C42H54FN9O5	2
1	EC50 = 2.5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
CP0445750 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-[(4-{[(pyridin-2-ylmethyl)amino]methyl}phenyl)formamido]propanamido]acetamido}pentanamide Show/Hide	C48H60N12O6	1
1	EC50 = 2.7 nM Bioactivity Info	TI LI LO TS
CP0850851 Compound Info	(2S)-1-((S)-4-amino-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)-4-oxobutanoyl)-N-((8S,11S,17S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-3-imino-11-isobutyl-10,13,16-trioxo-18-phenyl-2,4,9,12,14,15-hexaazaoctadecan-17-yl)-4-hydroxypyrrolidine-2-carboxamide Show/Hide	C60H79N17O12	1
1	EC50 = 2.8 nM Bioactivity Info	TI LI LO TS
CP0406554 Compound Info	2-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}phenyl 2-hydroxybenzoate Show/Hide	C48H56N10O9	1
1	EC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0427902 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-(pyridin-3-ylformamido)propanamido]acetamido}pentanamide Show/Hide	C40H51N11O6	1
1	EC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0505374 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-{[4-(hydroxymethyl)phenyl]formamido}-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C42H54N10O7	1
1	EC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0406558 Compound Info	(2S)-2-{2-[(2S)-2-{[4-(aminomethyl)phenyl]formamido}-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide Show/Hide	C42H55N11O6	1
1	EC50 = 3.1 nM Bioactivity Info	TI LI LO TS
CP0475215 Compound Info	(2S)-2-{2-[(2S)-2-[(2-aminophenyl)formamido]-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide Show/Hide	C41H53N11O6	1
1	EC50 = 3.1 nM Bioactivity Info	TI LI LO TS
CP0406552 Compound Info	(2S)-2-{2-[(2S)-2-[(4-{[bis(pyridin-2-ylmethyl)amino]methyl}phenyl)formamido]-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide Show/Hide	C54H65N13O6	1
1	EC50 = 3.3 nM Bioactivity Info	TI LI LO TS
CP0406557 Compound Info	(2S)-2-{2-[(2S)-2-({4-[(benzylamino)methyl]phenyl}formamido)-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide Show/Hide	C49H61N11O6	1
1	EC50 = 3.3 nM Bioactivity Info	TI LI LO TS
CP0158366 Compound Info	(2R,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pentanamide Show/Hide	C42H54FN9O6	2
1	EC50 = 4.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5.7 nM Bioactivity Info	TI LI LO TS
CP0848307 Compound Info	(S)-N1-((8S,11S,17S,20S)-8-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-ylcarbamoyl)-17-benzyl-3-imino-11-isobutyl-10,13,16,19-tetraoxo-20-phenyl-2,4,9,12,14,15,18-heptaazaicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide Show/Hide	C63H79N17O11	1
1	EC50 = 4.4 nM Bioactivity Info	TI LI LO TS
CP0406556 Compound Info	(2S)-2-{2-[(2S)-2-[(3-aminophenyl)formamido]-3-phenylpropanamido]acetamido}-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methylpentanamide Show/Hide	C41H53N11O6	1
1	EC50 = 4.7 nM Bioactivity Info	TI LI LO TS
CP0445745 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(2-hydroxyphenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C41H52N10O7	1
1	EC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0267258 Compound Info	(2E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-2-(2-methylpropyl)pent-2-enamide Show/Hide	C42H52FN9O5	2
1	EC50 = 5.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4.6 nM Bioactivity Info	TI LI LO TS
CP0477082 Compound Info	(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C50H69N15O10	1
1	EC50 = 7.7 nM Bioactivity Info	TI LI LO TS
CP0575491 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-[[(2S)-3-hydroxy-2-[3-(1H-indol-3-yl)propanoylamino]propanoyl]amino]-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide Show/Hide	C46H62N12O8	1
1	EC50 = 8.2 nM Bioactivity Info	TI LI LO TS
CP0520456 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]-2-[[[(2S)-2-amino-3-phenylpropanoyl]amino]carbamoylamino]-4-methylpentanamide Show/Hide	C32H48N10O5	1
1	EC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0406553 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-2-[(2,3,4,5,6-pentafluorophenyl)formamido]-3-phenylpropanamido]acetamido}pentanamide Show/Hide	C41H47F5N10O6	1
1	EC50 > 100 nM Bioactivity Info	TI LI LO TS
CP0475214 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-4-methyl-2-{2-[(2S)-3-phenyl-2-[(3,4,5-trihydroxyphenyl)formamido]propanamido]acetamido}pentanamide Show/Hide	C41H52N10O9	1
1	EC50 > 100 nM Bioactivity Info	TI LI LO TS
CP0487760 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-(3-piperazin-1-ylphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C27H22FN5O3	1
1	IC50 = 3.6 nM Bioactivity Info	TI LI LO TS
CP0454298 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C26H20FN5O4	2
1	IC50 = 3.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 460 nM Bioactivity Info	TI LI LO TS
CP0438744 Compound Info	N-[4-[3-[(2-aminoacetyl)amino]phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C25H18FN5O4	1
1	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
CP0373020 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[3-(methylamino)propanoylamino]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C27H22FN5O4	1
1	IC50 = 4.6 nM Bioactivity Info	TI LI LO TS
CP0514912 Compound Info	N-[3-cyano-4-[3-(1,4-diazepan-1-yl)phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C28H24FN5O3	1
1	IC50 = 7.3 nM Bioactivity Info	TI LI LO TS
CP0446441 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C26H20FN5O3S	2
1	IC50 = 7.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 3600 nM Bioactivity Info	TI LI LO TS
CP0487759 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[[2-[(2S)-pyrrolidin-2-yl]acetyl]amino]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H24FN5O4	1
1	IC50 = 7.9 nM Bioactivity Info	TI LI LO TS
CP0446442 Compound Info	N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C26H20FN5O4	2
1	IC50 = 8 nM Bioactivity Info	TI LI LO TS
2	IC50 = 660 nM Bioactivity Info	TI LI LO TS
CP0448306 Compound Info	N-[3-cyano-4-[3-[3-(ethylamino)pentanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C30H28FN5O4	1
1	IC50 = 8 nM Bioactivity Info	TI LI LO TS
CP0430721 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[[2-(methylamino)acetyl]amino]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C26H20FN5O4	1
1	IC50 = 8.4 nM Bioactivity Info	TI LI LO TS
CP0180522 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C63H84N18O14	2
1	IC50 = 9.67 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.051 nM Bioactivity Info	TI LI LO TS
CP0491036 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[3-(propan-2-ylamino)butanoylamino]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C30H28FN5O4	1
1	IC50 = 9.7 nM Bioactivity Info	TI LI LO TS
CP0931001 Compound Info	N-{3-Cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(piperazin-1-ylmethyl)phenyl]pyridin-2-yl}furan-2-carbox-amide trifluoroacetate Show/Hide	C30H25F4N5O5	1
1	IC50 = 9.7 nM Bioactivity Info	TI LI LO TS
CP0388158 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-6-(4-chloro-2-hydroxyphenyl)-3-cyanopyridin-2-yl]thiophene-2-carboxamide Show/Hide	C26H20ClN5O3S	2
1	IC50 = 9.8 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4100 nM Bioactivity Info	TI LI LO TS
CP0448305 Compound Info	N-[3-cyano-4-[3-[3-(ethylamino)butanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H26FN5O4	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0487758 Compound Info	N-[3-cyano-4-[3-[3-(dimethylamino)propanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C28H24FN5O4	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0504184 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[[2-[(2R)-pyrrolidin-2-yl]acetyl]amino]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H24FN5O4	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0504282 Compound Info	N-[3-cyano-4-[3-[3-[ethyl(methyl)amino]propanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H26FN5O4	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0505819 Compound Info	N-[4-[3-[(3-amino-2,2-dimethylpropyl)carbamoyl]phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H26FN5O4	2
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2500 nM Bioactivity Info	TI LI LO TS
CP0520918 Compound Info	N-[3-cyano-4-[3-(4-ethylpiperazin-1-yl)phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H26FN5O3	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0472475 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxy-4-methylphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C27H23N5O3S	2
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 910 nM Bioactivity Info	TI LI LO TS
CP0438701 Compound Info	N-[3-cyano-4-[3-[[2-(dimethylamino)acetyl]amino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C27H22FN5O4	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0446437 Compound Info	N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C26H21N5O4	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0504243 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[(2-piperidin-2-ylacetyl)amino]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C30H26FN5O4	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0487863 Compound Info	N-[4-[3-[(1-amino-2-methylpropan-2-yl)carbamoyl]phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C28H25N5O4	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0516512 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-(4-methylpiperazin-1-yl)phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C28H24FN5O3	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0543066 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[(2-piperidin-1-ylacetyl)amino]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C30H26FN5O4	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0491035 Compound Info	N-[3-cyano-4-[3-[3-(diethylamino)propanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C30H28FN5O4	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0509612 Compound Info	(2R)-N-[3-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-2-(furan-2-carbonylamino)pyridin-4-yl]phenyl]pyrrolidine-2-carboxamide Show/Hide	C28H22FN5O4	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0400806 Compound Info	N-[3-cyano-4-[3-[3-(diethylamino)butanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C31H30FN5O4	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0487756 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[[2-[(2S)-1-methylpyrrolidin-2-yl]acetyl]amino]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C30H26FN5O4	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0504244 Compound Info	N-[3-cyano-6-(4-fluoro-2-hydroxyphenyl)-4-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H26FN5O3	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0543054 Compound Info	N-[3-cyano-4-[3-[3-(dimethylamino)butanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H26FN5O4	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0225128 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C60H82N18O14	2
1	IC50 = 18.3 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0472474 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-6-(4-bromo-2-hydroxyphenyl)-3-cyanopyridin-2-yl]thiophene-2-carboxamide Show/Hide	C26H20BrN5O3S	2
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6300 nM Bioactivity Info	TI LI LO TS
CP0471032 Compound Info	N-[3-cyano-4-[3-[(4-ethylpiperazin-1-yl)methyl]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C30H28FN5O3	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0943905 Compound Info	N-[3-Cyano-4-(3-{[2-(dimethylamino)ethyl]carbamoyl}phenyl)-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide hydrochloride Show/Hide	C28H25ClFN5O4	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0446434 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C26H21N5O3S	2
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1100 nM Bioactivity Info	TI LI LO TS
CP0504183 Compound Info	N-[3-cyano-4-[3-[3-(diethylamino)pentanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C32H32FN5O4	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0912126 Compound Info	N-{3-Cyano-4-[3-(1,4-diazepan-1-ylmethyl)phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl}furan-2-carboxamide dihydrochloride Show/Hide	C29H28Cl2FN5O3	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0388164 Compound Info	N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C26H21N5O3S	2
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5100 nM Bioactivity Info	TI LI LO TS
CP0471031 Compound Info	N-[3-cyano-4-[3-[2-(dimethylamino)ethyl-methylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C28H26FN5O3	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0487757 Compound Info	N-[3-cyano-4-[3-[2-(ethylamino)butanoylamino]phenyl]-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide Show/Hide	C29H26FN5O4	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0388160 Compound Info	N-(2-aminoethyl)-3-[3-cyano-6-(2-hydroxyphenyl)-2-[(4-methoxybenzoyl)amino]pyridin-4-yl]benzamide Show/Hide	C29H25N5O4	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0123124 Compound Info	(2S,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pentanamide Show/Hide	C42H54FN9O6	1
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0166625 Compound Info	(2E,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pent-2-enamide Show/Hide	C42H52FN9O6	1
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0388161 Compound Info	N-[4-[3-[(1-amino-2-methylpropan-2-yl)carbamoyl]phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]-2-methoxybenzamide Show/Hide	C31H29N5O4	1
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0506194 Compound Info	N-(1-amino-2-methylpropan-2-yl)-3-[3-cyano-6-(2-hydroxyphenyl)-2-[(4-methoxybenzoyl)amino]pyridin-4-yl]benzamide Show/Hide	C31H29N5O4	1
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0446438 Compound Info	N-[4-[3-(4-aminobutanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C27H23N5O3S	2
1	IC50 = 34 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0334235 Compound Info	(2R)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C60H82N18O14	2
1	IC50 = 41.2 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.11 nM Bioactivity Info	TI LI LO TS
CP0388159 Compound Info	N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]-2-methoxybenzamide Show/Hide	C29H25N5O4	1
1	IC50 = 45 nM Bioactivity Info	TI LI LO TS
CP0388163 Compound Info	N-[4-[3-[(2-aminoacetyl)amino]phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C25H19N5O3S	2
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2800 nM Bioactivity Info	TI LI LO TS
CP0520842 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]benzamide Show/Hide	C28H23N5O3	2
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
2	IC50 = 24000 nM Bioactivity Info	TI LI LO TS
CP0083575 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C64H85N17O14	2
1	IC50 = 87 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.046 nM Bioactivity Info	TI LI LO TS
CP0504405 Compound Info	N-[4-[4-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C26H21N5O3S	1
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
CP0506196 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxy-4-methoxyphenyl)pyridin-2-yl]benzamide Show/Hide	C29H25N5O4	1
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
CP0460356 Compound Info	N-[3-cyano-4-[3-[[2-(dimethylamino)acetyl]amino]phenyl]-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C27H23N5O3S	1
1	IC50 = 180 nM Bioactivity Info	TI LI LO TS
CP0270119 Compound Info	(2R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C41H51FN10O6	1
1	IC50 = 240 nM Bioactivity Info	TI LI LO TS
CP0123122 Compound Info	(2S,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pentanamide Show/Hide	C42H54FN9O6	1
1	IC50 = 380 nM Bioactivity Info	TI LI LO TS
CP0137856 Compound Info	(2E,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-4-hydroxy-2-(2-methylpropyl)pent-2-enamide Show/Hide	C42H52FN9O6	1
1	IC50 = 460 nM Bioactivity Info	TI LI LO TS
CP0506195 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxy-5-methoxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C27H23N5O4S	1
1	IC50 = 480 nM Bioactivity Info	TI LI LO TS
CP0446440 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-6-(5-chloro-2-hydroxyphenyl)-3-cyanopyridin-2-yl]thiophene-2-carboxamide Show/Hide	C26H20ClN5O3S	1
1	IC50 = 490 nM Bioactivity Info	TI LI LO TS
CP0446433 Compound Info	N-[4-[3-(aminomethyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C24H18N4O2S	1
1	IC50 = 570 nM Bioactivity Info	TI LI LO TS
CP0388165 Compound Info	N-[6-(2-aminophenyl)-4-[3-(3-aminopropanoylamino)phenyl]-3-cyanopyridin-2-yl]benzamide Show/Hide	C28H24N6O2	1
1	IC50 = 890 nM Bioactivity Info	TI LI LO TS
CP0504406 Compound Info	N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)-5-methylpyridin-2-yl]furan-2-carboxamide Show/Hide	C27H23N5O4	1
1	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
CP0506193 Compound Info	N-[3-cyano-4-[3-(hydroxymethyl)phenyl]-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C24H17N3O3S	1
1	IC50 = 1500 nM Bioactivity Info	TI LI LO TS
CP0388162 Compound Info	N-[4-(3-aminophenyl)-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C23H16N4O2S	1
1	IC50 = 2100 nM Bioactivity Info	TI LI LO TS
CP0520841 Compound Info	3-{3-Cyano-6-(2-hydroxyphenyl)-2-[(thiophen-2-ylcarbonyl)amino]pyridin-4-yl}benzoic acid Show/Hide	C24H15N3O4S	1
1	IC50 = 9900 nM Bioactivity Info	TI LI LO TS
CP0446436 Compound Info	N-[4-(3-aminophenyl)-3-cyano-6-(2-methoxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C24H18N4O2S	1
1	IC50 > 30000 nM Bioactivity Info	TI LI LO TS
CP0446435 Compound Info	N-[4-[2-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide Show/Hide	C26H21N5O3S	1
1	IC50 = 33000 nM Bioactivity Info	TI LI LO TS
CP0366655 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C61H79N15O12	1
1	Ki = 0.032 nM Bioactivity Info	TI LI LO TS
CP0523493 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C65H85N19O13	1
1	Ki = 0.033 nM Bioactivity Info	TI LI LO TS
CP0366656 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C62H82N18O14	1
1	Ki = 0.045 nM Bioactivity Info	TI LI LO TS
CP0339422 Compound Info	(2R)-N-[(2R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C63H84N18O14	1
1	Ki = 0.052 nM Bioactivity Info	TI LI LO TS
CP0367957 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-4-amino-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoyl]amino]-3-cyclohexylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C61H89N17O14	1
1	Ki = 0.055 nM Bioactivity Info	TI LI LO TS
CP0350370 Compound Info	(2R)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C63H84N18O14	1
1	Ki = 0.062 nM Bioactivity Info	TI LI LO TS
CP0071237 Compound Info	(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C59H78N16O12	1
1	Ki = 0.065 nM Bioactivity Info	TI LI LO TS
CP0260603 Compound Info	(2S)-N-[(2R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C63H84N18O14	1
1	Ki = 0.078 nM Bioactivity Info	TI LI LO TS
CP0150085 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C57H77N15O12	1
1	Ki = 0.086 nM Bioactivity Info	TI LI LO TS
CP0366654 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C62H83N17O14	1
1	Ki = 0.086 nM Bioactivity Info	TI LI LO TS
CP0258966 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2R)-2-amino-3-pyridin-3-ylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]butanediamide Show/Hide	C58H77N17O11	1
1	Ki = 0.11 nM Bioactivity Info	TI LI LO TS
CP0071236 Compound Info	(2S)-2-[[(2S,3S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C54H79N15O12	1
1	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0247747 Compound Info	(2S)-N-[(2R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C60H82N18O14	1
1	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0258965 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-pyridin-3-ylpropanoyl]amino]butanediamide Show/Hide	C62H83N19O13	1
1	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0366653 Compound Info	(2R)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C61H83N17O14	1
1	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0258832 Compound Info	(2S)-2-[[(2S,3R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C52H75N15O13	1
1	Ki = 0.2 nM Bioactivity Info	TI LI LO TS
CP0258833 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-4-amino-2-[[(2R)-2-amino-3-pyridin-3-ylpropanoyl]amino]-4-oxobutanoyl]amino]-3-cyclohexylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C60H88N18O13	1
1	Ki = 0.2 nM Bioactivity Info	TI LI LO TS
CP0336463 Compound Info	(2S)-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2R)-2-amino-3-pyridin-3-ylpropanoyl]amino]-3-phenylpropanoyl]amino]butanediamide Show/Hide	C56H76N16O11	1
1	Ki = 0.2 nM Bioactivity Info	TI LI LO TS
CP0134996 Compound Info	(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C51H73N15O13	1
1	Ki = 0.21 nM Bioactivity Info	TI LI LO TS
CP0334234 Compound Info	(2R)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C60H82N18O14	1
1	Ki = 0.21 nM Bioactivity Info	TI LI LO TS
CP0105322 Compound Info	(2R)-N-[(2S,3R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C56H81N17O15	1
1	Ki = 0.29 nM Bioactivity Info	TI LI LO TS
CP0242406 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-aminopropanoyl]amino]butanediamide Show/Hide	C57H80N18O13	1
1	Ki = 0.51 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000389 , CHO-DXB11

Cell Line Info

Cell Line ID: CL000006 , HEK293

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0039237 Compound Info	(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]butanediamido]-3-(1H-indol-3-yl)propanamido]-N-[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]butanediamide Show/Hide	C63H83N17O14	4
1	IC50 = 0.082 nM
2	IC50 = 0.12 nM
3	Ki = 0.062 nM
4	Ki = 1.3 nM
CP0083575 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C64H85N17O14	1
1	IC50 = 0.11 nM
CP0158503 Compound Info	(2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-5-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]-2-(2-methylpropyl)pent-3-enamide Show/Hide	C42H52FN9O5	1
1	IC50 = 0.12 nM
CP0180522 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C63H84N18O14	1
1	IC50 = 0.16 nM
CP0260603 Compound Info	(2S)-N-[(2R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C63H84N18O14	1
1	IC50 = 0.19 nM
CP0247747 Compound Info	(2S)-N-[(2R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C60H82N18O14	1
1	IC50 = 0.28 nM
CP0225128 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxo-3-pyridin-4-ylpropan-2-yl]-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]butanediamide Show/Hide	C60H82N18O14	1
1	IC50 = 0.3 nM
CP0210913 Compound Info	(2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]-2-{2-[(2S)-2-[(4-fluorophenyl)formamido]-3-phenylpropanamido]acetamido}-4-methylpentanamide Show/Hide	C41H51FN10O6	1
1	IC50 = 0.71 nM
CP0083577 Compound Info	(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-pyridin-4-ylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-[(N'-methylcarbamimidoyl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]butanediamide Show/Hide	C56H76N16O12	2
1	IC50 ~ 8.94 nM
2	Ki ~ 0.089 nM
CP0263412 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C78H107N21O17	1
1	Ki = 0.8 nM
CP0263411 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C80H108N22O18	1
1	Ki = 1.6 nM
CP0311596 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C70H102N20O18	1
1	Ki = 1.8 nM
CP0307952 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-cyclohexylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C78H113N21O18	1
1	Ki = 2 nM
CP0289489 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-(pyridin-3-yl)ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C77H106N22O18	1
1	Ki = 4.7 nM
CP0311595 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}ethyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C79H109N21O18	1
1	Ki = 5 nM
CP0172588 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C80H108N22O18	1
1	Ki = 7.7 nM
CP0160204 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(pyridin-3-yl)ethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C77H106N22O18	1
1	Ki = 9.3 nM
CP0039239 Compound Info	(2S)-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}pentyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}butanediamide Show/Hide	C78H107N19O18	1
1	Ki = 9.4 nM
CP0039241 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-cyclohexylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C78H113N21O18	1
1	Ki = 11.1 nM
CP0192813 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}pentyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C78H107N21O18	1
1	Ki = 15.8 nM
CP0360703 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C78H107N21O19	1
1	Ki = 16.2 nM
CP0192815 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}ethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C77H106N20O17	1
1	Ki = 21.1 nM
CP0347616 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}ethyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C75H101N21O18	1
1	Ki = 29.5 nM
CP0171873 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C77H106N20O17	1
1	Ki = 33.4 nM
CP0336559 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S,2S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-2-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C78H107N21O18	1
1	Ki = 51.5 nM
CP0360704 Compound Info	(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]-N-[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}ethyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]butanediamide Show/Hide	C75H100N18O18	1
1	Ki = 82.7 nM
CP0192812 Compound Info	(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]-N-[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-4-(carbamoylamino)butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]butanediamide Show/Hide	C78H106N20O19	1
1	Ki = 88.1 nM
CP0296459 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-2-[[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]butanediamide Show/Hide	C81H112N22O19	1
1	Ki = 94.8 nM
CP0172585 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C75H105N23O18	1
1	Ki = 109.6 nM
CP0171871 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-3-methylbutyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C75H109N21O18	1
1	Ki = 141.8 nM
CP0363148 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C75H105N23O18	1
1	Ki = 161.8 nM
CP0160205 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]butyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C75H110N24O18	1
1	Ki = 196.7 nM
CP0363155 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C72H103N21O18	1
1	Ki = 198.3 nM
CP0171872 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C72H103N21O18	1
1	Ki = 240.2 nM
CP0160206 Compound Info	(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]-3-carbamoylpropanamido]-3-(1H-indol-3-yl)propanamido]-3-carbamoylpropanamido]-3-hydroxypropanamido]-N-({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)pentanediamide Show/Hide	C74H106N22O19	1
1	Ki = 298.2 nM
CP0263410 Compound Info	(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]-3-carbamoylpropanamido]-3-(1H-indol-3-yl)propanamido]-3-carbamoylpropanamido]-3-hydroxypropanamido]-3-phenylpropanamido]acetamido}-4-methylpentanamido]-5-carbamimidamidopentanamido]pentanediamide Show/Hide	C74H106N22O19	1
1	Ki = 494.9 nM
CP0160202 Compound Info	(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-oxobutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoic acid Show/Hide	C78H106N20O19	1
1	Ki = 551.8 nM
CP0171867 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C82H115N21O18	1
1	Ki = 775.2 nM
CP0039240 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C81H111N21O18	1
1	Ki = 10000 nM
CP0160203 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C75H110N24O18	1
1	Ki = 10000 nM
CP0171869 Compound Info	(2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-2-[[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]butanediamide Show/Hide	C76H104N20O17	1
1	Ki = 10000 nM
CP0171870 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C69H106N24O18	1
1	Ki = 10000 nM
CP0172583 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoylethyl]carbamoyl}butyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C66H99N21O18	1
1	Ki = 10000 nM
CP0360772 Compound Info	(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-({2-[(2S)-2-{[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}butyl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}carbamoyl)-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]butanediamide Show/Hide	C77H103N21O18	1
1	Ki = 10000 nM
CP0363147 Compound Info	(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-3-carbamoylpropanamido]-3-(4-hydroxyphenyl)propanamido]-N-[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}-3-phenylpropyl]carbamoyl}-3-methylbutyl]carbamoyl}methyl)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]butanediamide Show/Hide	C82H106N18O18	1
1	Ki = 10000 nM

Clinical Information about the Protein

Target 1 ( G-protein coupled receptor 54 (KISS1R) )

Target Type	Discontinued Target
Disease	1 Target-related Disease				1
1	Prostate cancer [ICD-11: 2C82.0]
Discontinued Drug(s)	1 Discontinued Drug				1
1	TAK-683	Drug Info	Discontinued in Phase 1	Prostate cancer

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About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han