Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[3-(4-aminobutanoylamino)phenyl]-3-cyano-6-(2-hydroxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
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 PubChem ID
CID: 136016360
Canonical SMILES
NCCCC(=O)Nc1cccc(c1)-c1cc(nc(NC(=O)c2cccs2)c1C#N)-c1ccccc1O
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Compound Formula C27H23N5O3S
Compound Structure
Protein Name
 Protein Info 
KiSS-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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RF amide receptor
Uniprot ID
Q969F8
Gene Name
KISS1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 34 nM
   TI
   LI
   LO
   TS
2
IC50 = 1400 nM
   TI
   LI
   LO
   TS