Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[3-(3-aminopropanoylamino)phenyl]-3-cyano-6-(2-hydroxy-5-methoxyphenyl)pyridin-2-yl]thiophene-2-carboxamide
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 PubChem ID
CID: 136016379
Canonical SMILES
COc1ccc(O)c(c1)-c1cc(-c2cccc(NC(=O)CCN)c2)c(C#N)c(NC(=O)c2cccs2)n1
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Compound Formula C27H23N5O4S
Compound Structure
Protein Name
 Protein Info 
KiSS-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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RF amide receptor
Uniprot ID
Q969F8
Gene Name
KISS1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS