Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[3-(2-aminoethylcarbamoyl)phenyl]-3-cyano-6-(4-fluoro-2-hydroxyphenyl)pyridin-2-yl]furan-2-carboxamide
    Show/Hide
 PubChem ID
CID: 136016407
Canonical SMILES
NCCNC(=O)c1cccc(c1)-c1cc(nc(NC(=O)c2ccco2)c1C#N)-c1ccc(F)cc1O
    Show/Hide
Compound Formula C26H20FN5O4
Compound Structure
Protein Name
 Protein Info 
KiSS-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
RF amide receptor
Uniprot ID
Q969F8
Gene Name
KISS1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
2
IC50 = 660 nM
   TI
   LI
   LO
   TS