| Compound ID |
Compound Name |
Compound Formula |
|
CP0386331
|
2-[4-(1H-pyrazol-5-yl)-2,3-dihydro-1H-inden-1-yl]-1H-imidazole
Show/Hide
|
C15H14N4
|
1
|
| 1 |
EC50 = 600 nM
|
|
|
|
CP0094131
|
(S)-6-(2-(pyridin-3-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C17H15N3
|
1
|
| 1 |
EC50 = 760 nM
|
|
|
|
CP0394382
|
2-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-imidazole
Show/Hide
|
C13H14N2
|
1
|
| 1 |
EC50 = 791 nM
|
|
|
|
CP0432099
|
4-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-5-methyl-1H-pyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 = 902 nM
|
|
|
|
CP0374408
|
2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-4-fluorophenyl)oxazole
Show/Hide
|
C15H12FN3O
|
1
|
| 1 |
EC50 = 990 nM
|
|
|
|
CP0387538
|
6-(2-chlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C12H11ClN2
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0443477
|
6-(2-fluorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C12H11FN2
|
1
|
| 1 |
EC50 = 1770 nM
|
|
|
|
CP0070621
|
2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)benzonitrile
Show/Hide
|
C13H11N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0372415
|
6-phenyl-6,7-di hydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C12H12N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0372416
|
6-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0372418
|
2-(2,3-dihydro-1H-inden-2-yl)-1H-imidazole
Show/Hide
|
C12H12N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0381834
|
6-phenyl-4,5,6,7-tetra hydro-1H-benzo[d]imidazole
Show/Hide
|
C13H14N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0381836
|
6-(2-(methoxy methyl)phenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C15H18N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0387536
|
6-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine
Show/Hide
|
C13H14N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0387537
|
6-(4-chlorophenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C13H13ClN2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0388057
|
6-(2-methoxyphenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0388099
|
6-(4-chlorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C12H11ClN2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394386
|
2-(2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C12H12N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0427948
|
6-(3-methoxyphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C13H14N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0428546
|
6-(3-methoxyphenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0431172
|
6-(3-chlorophenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C13H13ClN2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0443475
|
6-(2-chlorophenyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazole
Show/Hide
|
C13H13ClN2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0497555
|
6-(2-(methoxymethyl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0040617
|
6-(4-fluoro-2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0040622
|
6-(5-fluoro-2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0070307
|
(S)-6-(biphenyl-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C18H16N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0070312
|
(S)-6-(2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H14N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0086900
|
(S)-N-(2'-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)biphenyl-3-yl)methanesulfonamide
Show/Hide
|
C19H19N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0094129
|
(R)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)oxazole
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0094133
|
(S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)-N-methylethanesulfonamide
Show/Hide
|
C15H19N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0148986
|
(R)-2-(5-chloro-4-(methoxymethyl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C14H15ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0152026
|
6-(4-fluoro-2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H13FN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0174601
|
(S)-2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)benzonitrile
Show/Hide
|
C13H11N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0234407
|
6-(5-fluoro-2-(1H-pyrazol-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H13FN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0278671
|
6-(5-fluoro-2-(1H-pyrazol-1-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H13FN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0280468
|
(S)-2'-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-N-methylbiphenyl-3-carboxamide
Show/Hide
|
C20H19N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0297367
|
6-(2-fluoro-6-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H13FN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0307853
|
(S)-6-(2-(pyridin-4-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C17H15N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0308471
|
6-(4-fluoro-2-(1H-pyrazol-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C15H13FN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0374403
|
2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-5-fluorophenyl)oxazole
Show/Hide
|
C15H12FN3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0039841
|
ABT-866
Show/Hide
|
C12H15N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0162054
|
N-[2-chloro-5-(1H-imidazol-2-yl)-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide
Show/Hide
|
C14H16ClN3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386328
|
2-(5-chloro-4-methoxy-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C13H13ClN2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386330
|
N-[5-(1H-imidazol-2-yl)-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide
Show/Hide
|
C14H17N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386334
|
N-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]ethanesulfonamide
Show/Hide
|
C14H17N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386335
|
N-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]methanesulfonamide
Show/Hide
|
C13H15N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386337
|
1-(1H-imidazol-2-yl)-N-methyl-2,3-dihydro-1H-indene-4-carboxamide
Show/Hide
|
C14H15N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386339
|
2-[5-chloro-4-(1H-pyrazol-5-yl)-2,3-dihydro-1H-inden-1-yl]-1H-imidazole
Show/Hide
|
C15H13ClN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386341
|
2-(5-chloro-4-(1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C15H13ClN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0386402
|
N-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]propane-1-sulfonamide
Show/Hide
|
C15H19N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394385
|
2-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]pyridine
Show/Hide
|
C17H15N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394388
|
2-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1,3-oxazole
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0394391
|
3-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]pyridine
Show/Hide
|
C17H15N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0399603
|
2-[4-(1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-yl]-1H-imidazole
Show/Hide
|
C15H14N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0412851
|
4-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1-methylpyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0412854
|
3-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1-methylpyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0412855
|
5-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1-methylpyrazole
Show/Hide
|
C16H16N4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0412856
|
N-[1-(1H-imidazol-2-yl)-5-methyl-2,3-dihydro-1H-inden-4-yl]methanesulfonamide
Show/Hide
|
C14H17N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0412857
|
N-[6-chloro-3-(4,5-dihydro-1H-imidazol-2-ylmethoxy)-2-methylphenyl]methanesulfonamide
Show/Hide
|
C12H16ClN3O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0412860
|
2-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-1,3-thiazole
Show/Hide
|
C15H13N3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0432098
|
2-(4-methoxy-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C13H14N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0433560
|
4-[1-(1H-imidazol-2-yl)-2,3-dihydro-1H-inden-4-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C16H15N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0433564
|
2-(4-methoxy-5-methyl-2,3-dihydro-1H-inden-1-yl)-1H-imidazole
Show/Hide
|
C14H16N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0316893
|
(S)-2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)phenyl)oxazole
Show/Hide
|
C15H13N3O
|
1
|
| 1 |
EC50 > 1400 nM
|
|
|
|
CP0148987
|
(S)-6-(2-(pyrimidin-5-yl)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
Show/Hide
|
C16H14N4
|
1
|
| 1 |
EC50 > 6500 nM
|
|
|
|
CP0381815
|
3-[4-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbonyl]triazol-1-yl]-7-(diethylamino)chromen-2-one
Show/Hide
|
C30H33N9O5
|
2
|
| 1 |
IC50 = 1.2 nM
|
|
|
| 2 |
Ki = 0.1 nM
|
|
|
|
CP0381526
|
3-[4-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbonyl]triazol-1-yl]-7-hydroxychromen-2-one
Show/Hide
|
C26H24N8O6
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0415132
|
3-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbonyl]-7-hydroxychromen-2-one
Show/Hide
|
C24H23N5O6
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0072943
|
3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid
Show/Hide
|
C17H19N3O
|
3
|
| 1 |
IC50 = 10.8 nM
|
|
|
| 2 |
Ki = 4.8 nM
|
|
|
| 3 |
Ki = 47.4 nM
|
|
|
|
CP0381531
|
5-[[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carbothioyl]amino]-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
Show/Hide
|
C35H30N6O7S
|
2
|
| 1 |
IC50 = 16.3 nM
|
|
|
| 2 |
Ki = 7.3 nM
|
|
|
|
CP0381529
|
3-[4-[[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]methyl]triazol-1-yl]-7-(diethylamino)chromen-2-one
Show/Hide
|
C30H35N9O4
|
2
|
| 1 |
IC50 = 52.4 nM
|
|
|
| 2 |
Ki = 29.9 nM
|
|
|
|
CP0377739
|
[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-(dithiolan-3-yl)pentanoate
Show/Hide
|
C27H33NO2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0082953
|
2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride
Show/Hide
|
C19H23NO5
|
3
|
| 1 |
Ki = 0.038 nM
|
|
|
| 2 |
Ki = 0.90309 nM
|
|
|
| 3 |
Ki = 10 nM
|
|
|
|
CP0854007
|
[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-chroman-2-ylmethyl)-amine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 0.03981 nM
|
|
|
|
CP0210810
|
[(4aS,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C23H27N5O4
|
1
|
| 1 |
Ki = 0.07079 nM
|
|
|
|
CP0495472
|
N-[6-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]hexyl]-N-methylfuran-2-carboxamide
Show/Hide
|
C23H31N5O4
|
1
|
| 1 |
Ki = 0.1096 nM
|
|
|
|
CP0475365
|
[(4aS,8aR)-4-[4-(dipropylamino)-6,7-dimethoxyquinazolin-2-yl]-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C29H39N5O4
|
1
|
| 1 |
Ki = 0.1288 nM
|
|
|
|
CP0097484
|
CYCLAZOSIN
Show/Hide
|
C23H27N5O4
|
2
|
| 1 |
Ki = 0.1349 nM
|
|
|
| 2 |
Ki = 0.3236 nM
|
|
|
|
CP0519946
|
1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-(2-methoxy-6-propan-2-ylphenoxy)ethanone
Show/Hide
|
C30H39N5O5
|
1
|
| 1 |
Ki = 0.1514 nM
|
|
|
|
CP0163564
|
2-[2-[(3-chlorophenyl)methoxy]phenoxy]-N-[2-(2,6-dimethoxyphenoxy)ethyl]ethanamine
Show/Hide
|
C25H28ClNO5
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0879010
|
N-{6-[(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-methyl-amino]-hexyl}-3-dimethylaminomethyl-N-methyl-benzamide
Show/Hide
|
C28H40N6O3
|
1
|
| 1 |
Ki = 0.166 nM
|
|
|
|
CP0410683
|
benzyl (4aS,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxaline-1-carboxylate
Show/Hide
|
C26H31N5O4
|
1
|
| 1 |
Ki = 0.1905 nM
|
|
|
|
CP0882784
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(2-thienylcarbonyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C23H27N5O3S
|
1
|
| 1 |
Ki = 0.2399 nM
|
|
|
|
CP0105052
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(4-methylphenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0370354
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(3-methylphenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0040814
|
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C19H21N5O4
|
2
|
| 1 |
Ki = 0.28 nM
|
|
|
| 2 |
Ki = 0.4074 nM
|
|
|
|
CP0386945
|
N-[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]furan-2-carboxamide
Show/Hide
|
C20H23N5O4
|
1
|
| 1 |
Ki = 0.2818 nM
|
|
|
|
CP0410713
|
[(4aR,8aS)-4-[4-(dipropylamino)-6,7-dimethoxyquinazolin-2-yl]-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C29H39N5O4
|
1
|
| 1 |
Ki = 0.302 nM
|
|
|
|
CP0862789
|
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-[1,2]dithiolan-3-yl-ethanone
Show/Hide
|
C19H25N5O3S2
|
1
|
| 1 |
Ki = 0.309 nM
|
|
|
|
CP0872936
|
(+)-2-[(4aS,8aR)-4-(5-bromo-2-furoyl)octahydroquinoxalin-1(2H)-yl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C23H26BrN5O4
|
1
|
| 1 |
Ki = 0.309 nM
|
|
|
|
CP0483083
|
benzyl (4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxaline-1-carboxylate
Show/Hide
|
C26H31N5O4
|
1
|
| 1 |
Ki = 0.3802 nM
|
|
|
|
CP0180112
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(4-nitrophenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C25H28N2O7
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0316444
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(4-methoxyphenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C26H31NO6
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0327530
|
[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Show/Hide
|
C27H31N5O5
|
1
|
| 1 |
Ki = 0.4169 nM
|
|
|
|
CP0872837
|
(+)-2-[(4aS,8aR)-4-benzoyloctahydroquinoxalin-1(2H)-yl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
Ki = 0.4898 nM
|
|
|
|
CP0375896
|
N-[2-(2,6-dimethoxyphenyl)sulfanylethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C25H29NO4S
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0412412
|
2-[[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]amino]naphthalene-1,4-dione
Show/Hide
|
C25H25N5O4
|
1
|
| 1 |
Ki = 0.5248 nM
|
|
|
|
CP0847183
|
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-[1,2]dithiolan-3-yl-methanone
Show/Hide
|
C18H23N5O3S2
|
1
|
| 1 |
Ki = 0.537 nM
|
|
|
|
CP0316443
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C25H29NO5
|
2
|
| 1 |
Ki = 0.537 nM
|
|
|
| 2 |
Ki = 0.96708 nM
|
|
|
|
CP0184026
|
2-[2-[(2-chlorophenyl)methoxy]phenoxy]-N-[2-(2,6-dimethoxyphenoxy)ethyl]ethanamine
Show/Hide
|
C25H28ClNO5
|
1
|
| 1 |
Ki = 0.5623 nM
|
|
|
|
CP0035002
|
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
Show/Hide
|
C20H28N2O5S
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0048996
|
CAS_74191-85-8
Show/Hide
|
C23H25N5O5
|
2
|
| 1 |
Ki = 0.631 nM
|
|
|
| 2 |
Ki = 0.8128 nM
|
|
|
|
CP0247776
|
2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-[1,4]naphthoquinone
Show/Hide
|
C24H23N5O4
|
1
|
| 1 |
Ki = 0.6761 nM
|
|
|
|
CP0519947
|
1-[(4aS,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]ethanone
Show/Hide
|
C20H27N5O3
|
1
|
| 1 |
Ki = 0.7413 nM
|
|
|
|
CP0446806
|
1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2,2-dimethylpropan-1-one
Show/Hide
|
C23H33N5O3
|
1
|
| 1 |
Ki = 0.7762 nM
|
|
|
|
CP0404407
|
2-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-3-phenyl-3,4-dihydro-2H-naphthalen-1-one
Show/Hide
|
C27H29NO4
|
1
|
| 1 |
Ki = 0.786041 nM
|
|
|
|
CP0105050
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(3-nitrophenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C25H28N2O7
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0254827
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(2-methylphenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0416569
|
N-[2-(2,6-diethoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C27H33NO5
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0404393
|
2-(2,6-dimethoxyphenoxy)-N-[(3-phenyl-3,4-dihydro-2H-chromen-2-yl)methyl]ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 0.818226 nM
|
|
|
|
CP0441147
|
3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-2-phenyl-2,3-dihydrochromen-4-one
Show/Hide
|
C26H27NO5
|
1
|
| 1 |
Ki = 0.835056 nM
|
|
|
|
CP0475824
|
2-(2,6-dimethoxyphenoxy)-N-[(2-phenyl-2H-chromen-3-yl)methyl]ethanamine
Show/Hide
|
C26H27NO4
|
1
|
| 1 |
Ki = 0.835056 nM
|
|
|
|
CP0872835
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(5-methoxy-2-furoyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C24H29N5O5
|
1
|
| 1 |
Ki = 0.871 nM
|
|
|
|
CP0882785
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(5-methyl-2-furoyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C24H29N5O4
|
1
|
| 1 |
Ki = 0.871 nM
|
|
|
|
CP0390476
|
1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]hexan-1-one
Show/Hide
|
C24H35N5O3
|
1
|
| 1 |
Ki = 0.912 nM
|
|
|
|
CP0421980
|
N-[6-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]hexyl]-N-methyl-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C27H35N5O5
|
1
|
| 1 |
Ki = 0.9333 nM
|
|
|
|
CP0042265
|
2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
Ki = 0.96 nM
|
|
|
|
CP0184024
|
Clopenphendioxan
Show/Hide
|
C25H28ClNO5
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0422260
|
N-[2-[2-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]ethyldisulfanyl]ethyl]-N-methylfuran-2-carboxamide
Show/Hide
|
C21H27N5O4S2
|
1
|
| 1 |
Ki = 1.072 nM
|
|
|
|
CP0845244
|
[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-thiochroman-2-ylmethyl)-amine
Show/Hide
|
C26H29NO3S
|
1
|
| 1 |
Ki = 1.148 nM
|
|
|
|
CP0495611
|
1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-naphthalen-2-ylethanone
Show/Hide
|
C30H33N5O3
|
1
|
| 1 |
Ki = 1.175 nM
|
|
|
|
CP0505188
|
3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid (3-{4-[2-(3-nitrooxy-propoxy)-phenyl]-piperazin-1-yl}-propyl)-amide
Show/Hide
|
C33H36N4O7
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0861076
|
2-{[2-(2,6-Dimethoxy-phenoxy)-ethylamino]-methyl}-4-phenyl-3,4-dihydro-2H-naphthalen-1-one
Show/Hide
|
C27H29NO4
|
1
|
| 1 |
Ki = 1.23 nM
|
|
|
|
CP0855768
|
1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-5-[1,2]dithiolan-3-yl-pentan-1-one
Show/Hide
|
C22H31N5O3S2
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0882786
|
(+)-1-(5-{[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)octahydroquinoxalin-1(2H)-yl]carbonyl}-2-furyl)ethanone
Show/Hide
|
C25H29N5O5
|
1
|
| 1 |
Ki = 1.38 nM
|
|
|
|
CP0421978
|
[(4aS,8aR)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Show/Hide
|
C27H31N5O5
|
1
|
| 1 |
Ki = 1.413 nM
|
|
|
|
CP0437539
|
2-methoxy-5-[(2R)-2-[2-(2-propan-2-yloxyphenoxy)ethylamino]propyl]benzenesulfonamide
Show/Hide
|
C21H30N2O5S
|
1
|
| 1 |
Ki = 1.905 nM
|
|
|
|
CP0126496
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(3-methoxyphenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C26H31NO6
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0376824
|
2-methoxy-5-[(2R)-2-[2-(2-phenylmethoxyphenoxy)ethylamino]propyl]benzenesulfonamide
Show/Hide
|
C25H30N2O5S
|
1
|
| 1 |
Ki = 2.089 nM
|
|
|
|
CP0912440
|
(S)-2-[((2-(2,6-Dimethoxyphenoxy)ethyl)amino)methyl]-8-chloro-1,4-benzodioxane hydrochloride
Show/Hide
|
C19H23Cl2NO5
|
1
|
| 1 |
Ki = 2.188 nM
|
|
|
|
CP0910843
|
(S)-2-(2,6-dimethoxyphenoxy)-N-((8-fluoro-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C19H23ClFNO5
|
1
|
| 1 |
Ki = 2.399 nM
|
|
|
|
CP0289979
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(2-nitrophenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C25H28N2O7
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0943167
|
(S)-2-(2,6-dimethoxyphenoxy)-N-((8-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C20H26ClNO6
|
1
|
| 1 |
Ki = 2.754 nM
|
|
|
|
CP0892862
|
[2-(2-Benzyl-phenoxy)-ethyl]-[2-(2,6-dimethoxy-phenoxy)-ethyl]-amine
Show/Hide
|
C25H29NO4
|
1
|
| 1 |
Ki = 2.818 nM
|
|
|
|
CP0882783
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(1H-pyrrol-2-ylcarbonyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0405415
|
5-[(1S,1aR,6aS)-1-propyl-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C16H18N2
|
1
|
| 1 |
Ki = 3.548 nM
|
|
|
|
CP0345915
|
3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide
Show/Hide
|
C31H33N3O4
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0442589
|
3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid (3-{4-[2-(4-methyl-5-oxy-furazan-3-ylmethoxy)-phenyl]-piperazin-1-yl}-propyl)-amide
Show/Hide
|
C34H35N5O6
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0386458
|
N-[2-(2-methoxy-6-nitrophenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C24H26N2O6
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0416570
|
N-[2-(2-methoxy-6-methylphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C25H29NO4
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0068100
|
1-[2-(1,3-benzodioxol-5-yl)ethyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C20H24N2O3
|
1
|
| 1 |
Ki = 5.248 nM
|
|
|
|
CP0307245
|
1-[2-(1,3-benzodioxol-5-yl)ethyl]-4-(2-ethoxyphenyl)piperazine
Show/Hide
|
C21H26N2O3
|
1
|
| 1 |
Ki = 5.37 nM
|
|
|
|
CP0472991
|
2-methoxy-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]benzenesulfonamide
Show/Hide
|
C20H25F3N2O5S
|
1
|
| 1 |
Ki = 5.495 nM
|
|
|
|
CP0847195
|
(S)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride
Show/Hide
|
C19H24ClNO5
|
1
|
| 1 |
Ki = 5.754 nM
|
|
|
|
CP0433386
|
N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine
Show/Hide
|
C19H23NO5
|
1
|
| 1 |
Ki = 5.754 nM
|
|
|
|
CP0846086
|
(S)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine oxalate
Show/Hide
|
C21H25NO9
|
1
|
| 1 |
Ki = 5.754 nM
|
|
|
|
CP0858962
|
(+)-6,7-dimethoxy-2-[(4aS,8aR)-4-(pyridin-2-ylcarbonyl)octahydroquinoxalin-1(2H)-yl]quinazolin-4-amine
Show/Hide
|
C24H28N6O3
|
1
|
| 1 |
Ki = 5.888 nM
|
|
|
|
CP0411936
|
5-[(1aR,6S,6aR)-6-methyl-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C14H14N2
|
1
|
| 1 |
Ki = 6.166 nM
|
|
|
|
CP0254826
|
N-[2-(2,6-dimethoxyphenoxy)ethyl]-2-[2-[(2-methoxyphenyl)methoxy]phenoxy]ethanamine
Show/Hide
|
C26H31NO6
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0494781
|
3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid (3-{4-[2-(4-cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-piperazin-1-yl}-propyl)-amide
Show/Hide
|
C34H32N6O6
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0288408
|
1-[(4,4-diphenyl-1,3-dioxolan-2-yl)methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C27H30N2O3
|
1
|
| 1 |
Ki = 6.761 nM
|
|
|
|
CP0859288
|
1-((2,2-diphenyl-1,3-dioxolan-4-yl)methyl)-4-(2-methoxyphenyl)piperazine oxalate
Show/Hide
|
C29H32N2O7
|
1
|
| 1 |
Ki = 6.761 nM
|
|
|
|
CP0375932
|
3-(2,6-dimethoxyphenyl)-N-[2-(2-phenylmethoxyphenoxy)ethyl]propan-1-amine
Show/Hide
|
C26H31NO4
|
1
|
| 1 |
Ki = 6.918 nM
|
|
|
|
CP0460833
|
N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]-2-(trifluoromethyl)benzamide
Show/Hide
|
C24H24F3N3O3
|
1
|
| 1 |
Ki = 7.413 nM
|
|
|
|
CP0558773
|
(3S)-N-[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki = 7.413 nM
|
|
|
|
CP0411964
|
N-[2-(2-chloro-6-methoxyphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C24H26ClNO4
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0688480
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-(4-methylbenzenesulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C26H35N3O5S
|
1
|
| 1 |
Ki = 8.318 nM
|
|
|
|
CP0126495
|
N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C24H24F3N3O3
|
1
|
| 1 |
Ki = 8.913 nM
|
|
|
|
CP0374188
|
5-[(1aR,6S,6aS)-6-propyl-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C16H18N2
|
1
|
| 1 |
Ki = 8.913 nM
|
|
|
|
CP0905131
|
1-[(5,5-Diphenyloxolan-2-yl)methyl]-4-(2-methoxyphenyl)-piperazine Oxalate Salt
Show/Hide
|
C30H34N2O6
|
1
|
| 1 |
Ki = 8.913 nM
|
|
|
|
CP0446804
|
1-[(4aR,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]ethanone
Show/Hide
|
C20H27N5O3
|
1
|
| 1 |
Ki = 9.12 nM
|
|
|
|
CP0421705
|
8-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]-8-azaspiro[4.5]decane-7,9-dione
Show/Hide
|
C31H39N3O5
|
1
|
| 1 |
Ki = 9.333 nM
|
|
|
|
CP0489482
|
8-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]-8-azaspiro[4.5]decane-7,9-dione
Show/Hide
|
C31H39N3O5
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0132460
|
1-(2-ethoxyphenyl)-4-[2-(4-methoxyphenyl)ethyl]piperazine
Show/Hide
|
C21H28N2O2
|
1
|
| 1 |
Ki = 10.23 nM
|
|
|
|
CP0068101
|
1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
|
C23H32N2O3
|
1
|
| 1 |
Ki = 10.47 nM
|
|
|
|
CP0889460
|
(S)-2-[((2-(2-methoxy-5-phenylphenoxy)ethyl)amino)methyl]-1,4-benzodioxane hydrochloride
Show/Hide
|
C24H26ClNO4
|
1
|
| 1 |
Ki = 10.96 nM
|
|
|
|
CP0388614
|
5-[(1aR,6S,6aR)-6-propoxy-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C16H18N2O
|
1
|
| 1 |
Ki = 11.48 nM
|
|
|
|
CP0894510
|
[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-amine
Show/Hide
|
C27H31NO3
|
1
|
| 1 |
Ki = 12.3 nM
|
|
|
|
CP0393190
|
N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]furan-2-carboxamide
Show/Hide
|
C21H23N3O4
|
1
|
| 1 |
Ki = 12.3 nM
|
|
|
|
CP0459890
|
N-[(9-amino-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-3-yl)methyl]-3-(trifluoromethyl)benzamide;hydrochloride
Show/Hide
|
C24H25ClF3N3O3
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0375895
|
2-(2-ethoxyphenoxy)-N-[2-(2-phenylmethoxyphenoxy)ethyl]ethanamine
Show/Hide
|
C25H29NO4
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0132465
|
1-[2-(1,3-benzodioxol-5-yl)ethyl]-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
Ki = 12.88 nM
|
|
|
|
CP0403966
|
8-Chloro-2-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethylamino}-6-methyl-6H-1,6,7,9a-tetraaza-fluoren-5-one
Show/Hide
|
C22H23Cl2N7O
|
1
|
| 1 |
Ki = 13.6 nM
|
|
|
|
CP0154868
|
1-[2-(3-methoxyphenyl)ethyl]-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
|
C22H30N2O2
|
1
|
| 1 |
Ki = 13.8 nM
|
|
|
|
CP0454587
|
1-[2-(4-methoxyphenyl)ethyl]-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
|
C22H30N2O2
|
1
|
| 1 |
Ki = 14.79 nM
|
|
|
|
CP0234085
|
2-(2,2-diphenyl-1,3-dioxolan-4-yl)-N-[2-(2-methoxyphenoxy)ethyl]ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 14.79 nM
|
|
|
|
CP0394919
|
2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2H-benzo[e]isoindole-1,3-dione
Show/Hide
|
C31H35N3O3
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0447962
|
8-Chloro-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethylamino}-6-methyl-6H-1,6,7,9a-tetraaza-fluoren-5-one
Show/Hide
|
C23H26ClN7O2
|
1
|
| 1 |
Ki = 15.2 nM
|
|
|
|
CP0519411
|
8-Chloro-6-methyl-2-[2-(4-phenyl-piperazin-1-yl)-ethylamino]-6H-1,6,7,9a-tetraaza-fluoren-5-one
Show/Hide
|
C22H24ClN7O
|
1
|
| 1 |
Ki = 15.6 nM
|
|
|
|
CP0861255
|
(S)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2-methoxynaphthalen-1-yloxy)ethanamine hydrochloride
Show/Hide
|
C22H24ClNO4
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0373939
|
N-[2-(2,6-dimethoxyphenyl)sulfinylethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C25H29NO5S
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0132464
|
1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-ethoxyphenyl)piperazine
Show/Hide
|
C22H30N2O3
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0350499
|
N-[(2,2-diphenyl-1,3-dioxan-4-yl)methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0453508
|
4-[2-(4-{3-[(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carbonyl)-amino]-propyl}-piperazin-1-yl)-phenoxymethyl]-2-oxy-furazan-3-carboxylic acid amide
Show/Hide
|
C34H34N6O7
|
1
|
| 1 |
Ki = 15.9 nM
|
|
|
|
CP0374191
|
5-[(1S,1aR,6aS)-1-ethyl-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C15H16N2
|
1
|
| 1 |
Ki = 16.6 nM
|
|
|
|
CP0116923
|
8-benzyl-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
Ki = 16.6 nM
|
|
|
|
CP0881025
|
(S)-2-[((2-(2-methoxy-6-phenylphenoxy)ethyl)amino)methyl]-1,4-benzodioxane hydrochloride
Show/Hide
|
C24H26ClNO4
|
1
|
| 1 |
Ki = 17.78 nM
|
|
|
|
CP0415318
|
1-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]azepan-2-one
Show/Hide
|
C28H37N3O4
|
1
|
| 1 |
Ki = 18.2 nM
|
|
|
|
CP0933240
|
(S)-2-[((2-(2-methoxy-5,6,7,8-tetrahydronaphthoxy)ethyl)amino)methyl]-1,4-benzodioxane hydrochloride
Show/Hide
|
C22H28ClNO4
|
1
|
| 1 |
Ki = 19.05 nM
|
|
|
|
CP0382789
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-propan-2-yloxyphenoxy)ethanamine
Show/Hide
|
C27H31NO4
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0411965
|
2-(2-methoxyphenoxy)-N-[2-(2-phenylmethoxyphenoxy)ethyl]ethanamine
Show/Hide
|
C24H27NO4
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0847727
|
Carboxy-methanecarboxylate(2,2-diphenyl-[1,3]dioxolan-4-ylmethyl)-dimethyl-(2-phenoxy-ethyl)-ammonium
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
Ki = 20.42 nM
|
|
|
|
CP0402212
|
N-[[(2R)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
2
|
| 1 |
Ki = 21.88 nM
|
|
|
| 2 |
Ki = 56.23 nM
|
|
|
|
CP0087722
|
N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-2,3-dihydro-1-benzofuran-7-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C20H24ClNO5
|
1
|
| 1 |
Ki = 21.88 nM
|
|
|
|
CP0437121
|
5-Acetyl-4-amino-2-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-6-phenyl-2H-pyridazin-3-one
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
Ki = 22.1 nM
|
|
|
|
CP0496434
|
[(4aS,8aS)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Show/Hide
|
C27H31N5O5
|
1
|
| 1 |
Ki = 22.39 nM
|
|
|
|
CP0394914
|
2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2H-pyrrolo[3,4-c]pyridine-1,3-dione
Show/Hide
|
C26H32N4O3
|
1
|
| 1 |
Ki = 22.4 nM
|
|
|
|
CP0421822
|
1-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H32N2O3
|
1
|
| 1 |
Ki = 22.91 nM
|
|
|
|
CP0240495
|
1-(2-ethoxyphenyl)-4-[2-(3-methoxyphenyl)ethyl]piperazine
Show/Hide
|
C21H28N2O2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0482650
|
2-[[(3R)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]amino]naphthalene-1,4-dione
Show/Hide
|
C25H25N5O4
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0222921
|
N-(2-benzhydryloxyethyl)-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C25H27NO6
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0869545
|
[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(4-phenyl-thiochroman-2-ylmethyl)-amine
Show/Hide
|
C26H29NO3S
|
1
|
| 1 |
Ki = 27.54 nM
|
|
|
|
CP0326120
|
N-[[(2S,4S)-2-benzhydryl-1,3-dioxolan-4-yl]methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 27.54 nM
|
|
|
|
CP0108664
|
N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-1-benzofuran-7-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C20H22ClNO5
|
1
|
| 1 |
Ki = 28.84 nM
|
|
|
|
CP0917590
|
(S)-2-[((2-(2,6-Dimethoxyphenoxy)ethyl)amino)methyl]-8-hydroxy-1,4-benzodioxane hydrochloride
Show/Hide
|
C19H24ClNO6
|
1
|
| 1 |
Ki = 30.9 nM
|
|
|
|
CP0204599
|
2-[(2S,4S)-2-benzhydryl-1,3-dioxolan-4-yl]-N-[2-(2-methoxyphenoxy)ethyl]ethanamine;oxalic acid
Show/Hide
|
C29H33NO8
|
1
|
| 1 |
Ki = 30.9 nM
|
|
|
|
CP0394897
|
2-methoxy-5-[(2R)-2-[[(2R,3S)-2-methyl-2,3-dihydro-1,4-benzodioxin-3-yl]methylamino]propyl]benzenesulfonamide
Show/Hide
|
C20H26N2O5S
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0230606
|
N-[(2,2-diphenyl-1,3-dioxan-5-yl)methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0375630
|
5-[(1S,1aR,6aS)-1-methyl-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C14H14N2
|
1
|
| 1 |
Ki = 33.11 nM
|
|
|
|
CP0860648
|
(R)-2-[((2-(2,6-Dimethoxyphenoxy)ethyl)amino)methyl]-8-chloro-1,4-benzodioxane hydrochloride
Show/Hide
|
C19H23Cl2NO5
|
1
|
| 1 |
Ki = 33.88 nM
|
|
|
|
CP0243183
|
N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-2,3-dihydro-1H-indol-7-yl)oxy]ethanamine;dihydrochloride
Show/Hide
|
C20H26Cl2N2O4
|
1
|
| 1 |
Ki = 35.48 nM
|
|
|
|
CP0356931
|
N-[[(2S,4R)-2-benzhydryl-1,3-dioxolan-4-yl]methyl]-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C28H31NO8
|
1
|
| 1 |
Ki = 37.15 nM
|
|
|
|
CP0483388
|
3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C26H33N3O5
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0374189
|
5-[(1aR,6aR)-1a-methyl-1,6-dihydrocyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C14H14N2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0405414
|
5-[(1aR,6S,6aR)-6-ethoxy-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C15H16N2O
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0894525
|
[(5,5-Diphenyloxolan-2-yl)methyl][2-(2-methoxyphenoxy)-ethyl]amine Oxalate Salt
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0386135
|
5-[(1aR,6S,6aS)-6-ethyl-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C15H16N2
|
1
|
| 1 |
Ki = 40.74 nM
|
|
|
|
CP0390411
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-3-(2-methoxyphenyl)propan-1-amine
Show/Hide
|
C26H29NO3
|
1
|
| 1 |
Ki = 41.69 nM
|
|
|
|
CP0688481
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C19H29N3O3
|
1
|
| 1 |
Ki = 42.66 nM
|
|
|
|
CP0566392
|
N-[(3R)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]furan-2-carboxamide
Show/Hide
|
C20H23N5O4
|
1
|
| 1 |
Ki = 42.66 nM
|
|
|
|
CP0405465
|
6-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-6H-pyrrolo[3,4-b]pyridine-5,7-dione
Show/Hide
|
C26H32N4O3
|
1
|
| 1 |
Ki = 44.6 nM
|
|
|
|
CP0750872
|
N-((2,2-diphenyl-1,3-dioxolan-4-yl)methyl)-2-(2-methoxyphenoxy)ethanamine oxalate
Show/Hide
|
C27H29NO8
|
2
|
| 1 |
Ki = 45.71 nM
|
|
|
| 2 |
Ki = 46.77 nM
|
|
|
|
CP0390409
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0416404
|
1-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]piperidine-2,6-dione
Show/Hide
|
C27H33N3O5
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0464900
|
(3R)-N-[(3R)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0408404
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(2-methoxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C22H27NO4
|
1
|
| 1 |
Ki = 48.98 nM
|
|
|
|
CP0411877
|
1-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]piperidin-2-one
Show/Hide
|
C27H35N3O4
|
1
|
| 1 |
Ki = 51.29 nM
|
|
|
|
CP0409005
|
N-[[(2R)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
2
|
| 1 |
Ki = 52.48 nM
|
|
|
| 2 |
Ki = 120.23 nM
|
|
|
|
CP0373754
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-ethoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 53.7 nM
|
|
|
|
CP0412413
|
2-[(3S)-3-aminopiperidin-1-yl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C15H21N5O2
|
1
|
| 1 |
Ki = 54.95 nM
|
|
|
|
CP0414228
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 56.23 nM
|
|
|
|
CP0350497
|
N-[(2,2-diphenyl-1,3-dioxan-4-yl)methyl]-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 56.23 nM
|
|
|
|
CP0382790
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(3-methoxyphenoxy)ethanamine
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
Ki = 58.88 nM
|
|
|
|
CP0408405
|
[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl-[2-(2-methoxy-5-phenylphenoxy)ethyl]azanium;chloride
Show/Hide
|
C24H25NO4
|
1
|
| 1 |
Ki = 61.66 nM
|
|
|
|
CP0746429
|
N-((2,2-diphenyl-1,3-dioxolan-4-yl)methyl)-2-phenoxyethanamine oxalate
Show/Hide
|
C26H27NO7
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0400291
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-phenoxyethanamine
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0763928
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-[4-(trifluoromethyl)benzoyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C27H32F3N3O4
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0464898
|
(3R)-N-[(3S)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0061623
|
8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione
Show/Hide
|
C22H31N3O3
|
2
|
| 1 |
Ki = 64.57 nM
|
|
|
| 2 |
Ki = 707.95 nM
|
|
|
|
CP0356932
|
2-[(2S,4R)-2-benzhydryl-1,3-dioxolan-4-yl]-N-[2-(2-methoxyphenoxy)ethyl]ethanamine;oxalic acid
Show/Hide
|
C29H33NO8
|
1
|
| 1 |
Ki = 64.57 nM
|
|
|
|
CP0037866
|
CAS_146714-97-8
Show/Hide
|
C25H34N4O2
|
1
|
| 1 |
Ki = 66.07 nM
|
|
|
|
CP0780574
|
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide tri hydrochloride
Show/Hide
|
C25H35ClN4O2
|
1
|
| 1 |
Ki = 66.07 nM
|
|
|
|
CP0394967
|
2-methoxy-5-[(2R)-2-[[(2S,3R)-2-methyl-2,3-dihydro-1,4-benzodioxin-3-yl]methylamino]propyl]benzenesulfonamide
Show/Hide
|
C20H26N2O5S
|
1
|
| 1 |
Ki = 67.61 nM
|
|
|
|
CP0657012
|
8-Benzoyl-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C26H33N3O4
|
1
|
| 1 |
Ki = 67.61 nM
|
|
|
|
CP0535381
|
N-[(3,3-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 67.61 nM
|
|
|
|
CP0455988
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-8-(3-nitrophenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C25H32N4O7S
|
1
|
| 1 |
Ki = 69.18 nM
|
|
|
|
CP0697681
|
8-(4-Chlorobenzenesulfonyl)-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C25H32ClN3O5S
|
1
|
| 1 |
Ki = 69.18 nM
|
|
|
|
CP0415317
|
1-[[(2R,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidin-2-one
Show/Hide
|
C26H33N3O4
|
1
|
| 1 |
Ki = 70.79 nM
|
|
|
|
CP0904595
|
(R)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride
Show/Hide
|
C19H24ClNO5
|
1
|
| 1 |
Ki = 72.44 nM
|
|
|
|
CP0415319
|
1-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]azepan-2-one
Show/Hide
|
C28H37N3O4
|
1
|
| 1 |
Ki = 72.44 nM
|
|
|
|
CP0118815
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine
Show/Hide
|
C19H23NO5
|
1
|
| 1 |
Ki = 72.44 nM
|
|
|
|
CP0846429
|
(R)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanamine oxalate
Show/Hide
|
C21H25NO9
|
1
|
| 1 |
Ki = 72.44 nM
|
|
|
|
CP0435761
|
N-[[(2R)-5,5-diphenyl-1,4-dioxan-2-yl]methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 74.13 nM
|
|
|
|
CP0854278
|
trans-5-({[2-(2-Methoxyphenoxy)ethyl]amino}methyl)-2,2-diphenylcyclopentan-1-ol Oxalate Salt
Show/Hide
|
C29H33NO7
|
1
|
| 1 |
Ki = 74.13 nM
|
|
|
|
CP0232093
|
1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 74.13 nM
|
|
|
|
CP0373783
|
2-(2,6-dimethoxyphenoxy)-N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]ethanamine
Show/Hide
|
C26H29NO5
|
1
|
| 1 |
Ki = 75.86 nM
|
|
|
|
CP0067759
|
1-(2-phenylethyl)-4-(2-propan-2-yloxyphenyl)piperazine
Show/Hide
|
C21H28N2O
|
1
|
| 1 |
Ki = 77.62 nM
|
|
|
|
CP0440492
|
N-[(9-amino-6,7-dimethoxy-2,3-dihydro-1H-cyclopenta[b]quinolin-2-yl)methyl]furan-2-carboxamide
Show/Hide
|
C20H21N3O4
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0416571
|
N-[2-(2,6-dichlorophenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C23H23Cl2NO3
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0912439
|
(R)-2-(2,6-dimethoxyphenoxy)-N-((8-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C20H26ClNO6
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0705393
|
{[(4R)-2,2-diphenyl-1,3-dioxolan-4-yl]methyl}(2-phenoxyethyl)amine oxalate
Show/Hide
|
C26H27NO7
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0147893
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-N-phenyl-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C26H34N4O4
|
1
|
| 1 |
Ki = 81.28 nM
|
|
|
|
CP0846825
|
(R)-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(2-methoxynaphthalen-1-yloxy)ethanaminium chloride
Show/Hide
|
C22H24ClNO4
|
1
|
| 1 |
Ki = 85.11 nM
|
|
|
|
CP0374560
|
1-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidine-2,5-dione
Show/Hide
|
C26H31N3O5
|
1
|
| 1 |
Ki = 85.11 nM
|
|
|
|
CP0250925
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-8-thiophen-2-ylsulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C23H31N3O5S2
|
1
|
| 1 |
Ki = 85.11 nM
|
|
|
|
CP0433574
|
8-(benzenesulfonyl)-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C25H33N3O5S
|
1
|
| 1 |
Ki = 85.11 nM
|
|
|
|
CP0154869
|
1-(2-methoxyphenyl)-4-(2-phenylethyl)piperazine
Show/Hide
|
C19H24N2O
|
1
|
| 1 |
Ki = 91.2 nM
|
|
|
|
CP0366049
|
2-benzhydryloxy-3-[2-(2-methoxyphenoxy)ethylamino]propan-1-ol;oxalic acid
Show/Hide
|
C27H31NO8
|
1
|
| 1 |
Ki = 91.2 nM
|
|
|
|
CP0230604
|
2-(2,2-diphenyl-1,3-dioxolan-4-yl)-N-(2-phenoxyethyl)ethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 95.5 nM
|
|
|
|
CP0390410
|
N-[(2,2-diphenyl-1,3-oxathiolan-5-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C25H27NO3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0373940
|
N-[2-(2,6-dimethylphenoxy)ethyl]-2-(2-phenylmethoxyphenoxy)ethanamine
Show/Hide
|
C25H29NO3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0439525
|
2-[2-[2-(2-phenylmethoxyphenoxy)ethylamino]ethoxy]benzene-1,3-diol
Show/Hide
|
C23H25NO5
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0497240
|
2-phenoxy-N-[2-(2-phenylmethoxyphenoxy)ethyl]ethanamine
Show/Hide
|
C23H25NO3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0912441
|
(R)-2-(2,6-dimethoxyphenoxy)-N-((8-fluoro-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C19H23ClFNO5
|
1
|
| 1 |
Ki = 102.33 nM
|
|
|
|
CP0361338
|
N-[[(2S,4R)-2-benzhydryl-1,3-dioxolan-4-yl]methyl]-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 102.33 nM
|
|
|
|
CP0459292
|
N-[[(2S,4S)-2-benzhydryl-1,3-dioxolan-4-yl]methyl]-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 102.33 nM
|
|
|
|
CP0464670
|
2-(4,5-dihydro-1H-imidazol-2-yl)-1-(3-methoxyphenyl)-1-(4-methylphenyl)hydrazine
Show/Hide
|
C17H20N4O
|
1
|
| 1 |
Ki = 102.8 nM
|
|
|
|
CP0350496
|
2-[(2S,4R)-2-benzhydryl-1,3-dioxolan-4-yl]-N-(2-phenoxyethyl)ethanamine;oxalic acid
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
Ki = 107.15 nM
|
|
|
|
CP0272023
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-8-(4-nitrophenyl)sulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C25H32N4O7S
|
1
|
| 1 |
Ki = 109.65 nM
|
|
|
|
CP0802344
|
8-Cyclohexanecarbonyl-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C26H39N3O4
|
1
|
| 1 |
Ki = 109.65 nM
|
|
|
|
CP0751060
|
{[(4S)-2,2-diphenyl-1,3-dioxolan-4-yl]methyl}(2-phenoxyethyl)amine oxalate
Show/Hide
|
C26H27NO7
|
1
|
| 1 |
Ki = 114.82 nM
|
|
|
|
CP0396049
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-pyridin-2-yloxyethanamine
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
Ki = 114.82 nM
|
|
|
|
CP0373753
|
N-[(2,2-diphenyl-1,3-dithiolan-4-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C25H27NO2S2
|
1
|
| 1 |
Ki = 117.49 nM
|
|
|
|
CP0408073
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 120.23 nM
|
|
|
|
CP0396050
|
2-(2-chlorophenoxy)-N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C25H26ClNO3
|
1
|
| 1 |
Ki = 120.23 nM
|
|
|
|
CP0859341
|
[(5,5-Diphenyloxolan-2-yl)methyl](2-phenoxyethyl)amine Oxalate Salt
Show/Hide
|
C27H29NO6
|
1
|
| 1 |
Ki = 123.03 nM
|
|
|
|
CP0378503
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R)-5,5-diphenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0406705
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-1-benzofuran-7-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C20H22ClNO5
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0121063
|
1-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C20H30N2O3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0406086
|
1-[[(2S,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]piperidin-2-one
Show/Hide
|
C27H35N3O4
|
1
|
| 1 |
Ki = 128.82 nM
|
|
|
|
CP0311688
|
N-tert-butyl-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C24H38N4O4
|
1
|
| 1 |
Ki = 128.82 nM
|
|
|
|
CP0489497
|
1-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]piperidine-2,6-dione
Show/Hide
|
C27H33N3O5
|
1
|
| 1 |
Ki = 131.83 nM
|
|
|
|
CP0382788
|
2-(3,4-dimethoxyphenoxy)-N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]ethanamine
Show/Hide
|
C26H29NO5
|
1
|
| 1 |
Ki = 138.04 nM
|
|
|
|
CP0374257
|
N-[[(2R)-5,5-diphenyl-1,4-dioxan-2-yl]methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 141.25 nM
|
|
|
|
CP0859289
|
5-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,2-diphenylcyclopentan-1-one Oxalate Salt
Show/Hide
|
C31H34N2O6
|
1
|
| 1 |
Ki = 141.25 nM
|
|
|
|
CP0250926
|
1-(1,4-dioxa-8-thiaspiro[4.5]decan-3-ylmethyl)-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C19H28N2O3S
|
1
|
| 1 |
Ki = 141.25 nM
|
|
|
|
CP0772147
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-[4(trifluoromethoxy)benzenesulfonyl]-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C26H32F3N3O6S
|
1
|
| 1 |
Ki = 147.91 nM
|
|
|
|
CP0405158
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2-methoxy-6-phenylphenoxy)ethanamine;hydrochloride
Show/Hide
|
C24H25NO4
|
1
|
| 1 |
Ki = 151.36 nM
|
|
|
|
CP0657011
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-phenyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
Ki = 154.88 nM
|
|
|
|
CP0115843
|
[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-pyrrolidin-2-ylmethanone
Show/Hide
|
C24H36N4O4
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0763926
|
8-(Furan-2-carbonyl)-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C24H31N3O5
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0500849
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-2,3-dihydro-1-benzofuran-7-yl)oxy]ethanamine;hydrochloride
Show/Hide
|
C20H24ClNO5
|
1
|
| 1 |
Ki = 162.18 nM
|
|
|
|
CP0854275
|
cis-5-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,2-diphenylcyclopentan-1-ol Oxalate salt
Show/Hide
|
C31H36N2O6
|
1
|
| 1 |
Ki = 165.96 nM
|
|
|
|
CP0471912
|
2-[(2S,4S)-2-benzhydryl-1,3-dioxolan-4-yl]-N-(2-phenoxyethyl)ethanamine;oxalic acid
Show/Hide
|
C28H31NO7
|
1
|
| 1 |
Ki = 165.96 nM
|
|
|
|
CP0477118
|
N-[[(2S)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 169.82 nM
|
|
|
|
CP0373784
|
2-(2,3-dimethoxyphenoxy)-N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]ethanamine
Show/Hide
|
C26H29NO5
|
1
|
| 1 |
Ki = 173.78 nM
|
|
|
|
CP0415316
|
1-[[(2R,4S)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidin-2-one
Show/Hide
|
C26H33N3O4
|
1
|
| 1 |
Ki = 173.78 nM
|
|
|
|
CP0374190
|
5-[(1aR,6aR)-1,1-dimethyl-1a,6-dihydrocyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C15H16N2
|
1
|
| 1 |
Ki = 177.83 nM
|
|
|
|
CP0389458
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methylphenoxy)ethanamine
Show/Hide
|
C26H29NO3
|
1
|
| 1 |
Ki = 177.83 nM
|
|
|
|
CP0386946
|
2-[(3R)-3-aminopiperidin-1-yl]-6,7-dimethoxyquinazolin-4-amine
Show/Hide
|
C15H21N5O2
|
1
|
| 1 |
Ki = 177.83 nM
|
|
|
|
CP0862493
|
(S)-2-[((2-(2-methoxy-4-phenylphenoxy)ethyl)amino)methyl]-1,4-benzodioxane hydrochloride
Show/Hide
|
C24H26ClNO4
|
1
|
| 1 |
Ki = 186.21 nM
|
|
|
|
CP0445299
|
1-(2-methoxyphenyl)-4-(1-oxa-4-thiaspiro[4.5]decan-2-ylmethyl)piperazine
Show/Hide
|
C20H30N2O2S
|
1
|
| 1 |
Ki = 190.55 nM
|
|
|
|
CP0384764
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C27H31NO5
|
2
|
| 1 |
Ki = 194.98 nM
|
|
|
| 2 |
Ki = 323.59 nM
|
|
|
|
CP0503951
|
N-(1,4-dithiaspiro[4.5]decan-3-ylmethyl)-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C18H27NO2S2
|
1
|
| 1 |
Ki = 194.98 nM
|
|
|
|
CP0853819
|
(E)-N-(2-Dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-acrylamide TFA
Show/Hide
|
C37H40F3N3O3
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0415073
|
3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-6,7-dimethoxy-2,3,4,10-tetrahydro-1H-acridin-9-one
Show/Hide
|
C26H32N2O6
|
1
|
| 1 |
Ki = 218.78 nM
|
|
|
|
CP0503955
|
2-(2-methoxyphenoxy)-N-(1-oxa-4-thiaspiro[4.5]decan-2-ylmethyl)ethanamine
Show/Hide
|
C18H27NO3S
|
1
|
| 1 |
Ki = 218.78 nM
|
|
|
|
CP0406100
|
1-[[(2S,4R)-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-2-phenyl-1,3-dioxolan-2-yl]methyl]pyrrolidine-2,5-dione
Show/Hide
|
C26H31N3O5
|
1
|
| 1 |
Ki = 223.87 nM
|
|
|
|
CP0116478
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
Ki = 223.87 nM
|
|
|
|
CP0373781
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-methylphenoxy)ethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 239.88 nM
|
|
|
|
CP0802345
|
N-butyl-2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C24H38N4O4
|
1
|
| 1 |
Ki = 239.88 nM
|
|
|
|
CP0854276
|
trans-5-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,2-diphenylcyclopentan-1-ol Oxalate
Show/Hide
|
C31H36N2O6
|
1
|
| 1 |
Ki = 245.47 nM
|
|
|
|
CP0389457
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-nitrophenoxy)ethanamine
Show/Hide
|
C25H26N2O5
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0848345
|
Carboxy-methanecarboxylate(2,2-diphenyl-[1,3]dioxolan-4-ylmethyl)-methyl-(2-phenoxy-ethyl)-ammonium
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 257.04 nM
|
|
|
|
CP0378505
|
2-(2-methoxyphenoxy)-N-[[(2R,5R)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 263.03 nM
|
|
|
|
CP0378504
|
2-(2-methoxyphenoxy)-N-[[(2R,6S)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 269.15 nM
|
|
|
|
CP0402211
|
2-(2-methoxyphenoxy)-N-[[(2R,5S)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 281.84 nM
|
|
|
|
CP0347659
|
N-[(2,2-diphenyl-1,3-dioxan-5-yl)methyl]-2-phenoxyethanamine;oxalic acid
Show/Hide
|
C27H29NO7
|
1
|
| 1 |
Ki = 281.84 nM
|
|
|
|
CP0854274
|
trans-5-{[(2-Phenoxyethyl)amino]methyl}-2,2-diphenylcyclopentan-1-ol Oxalate Salt
Show/Hide
|
C28H31NO6
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0688479
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8lambda6-thiaspiro[4.5]decane-8,8-dione
Show/Hide
|
C19H28N2O5S
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0389448
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-[2-(methoxymethoxy)phenoxy]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0382852
|
N-[(6,7-dimethoxy-9-oxo-2,3,4,10-tetrahydro-1H-acridin-3-yl)methyl]furan-2-carboxamide
Show/Hide
|
C21H22N2O5
|
1
|
| 1 |
Ki = 295.12 nM
|
|
|
|
CP0371702
|
2-(2-methoxyphenoxy)-N-[[(2R,6R)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0847634
|
(E)-N-[4'-(Phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-N-pyridin-3-ylmethyl-acrylamide TFA
Show/Hide
|
C39H36F3N3O3
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0861232
|
3-Cyclopentyl-N-(2-dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-propionamide with di TFA
Show/Hide
|
C38H47F6N3O5
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0405413
|
5-[(1aR,6S,6aR)-6-propan-2-yloxy-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C16H18N2O
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0464899
|
(3S)-N-[(3R)-1-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperidin-3-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0415219
|
2-(2,6-dimethoxyphenoxy)-N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki = 323.59 nM
|
|
|
|
CP0068597
|
1-(2-methoxyphenyl)-4-(1,4,8-trioxaspiro[4.5]decan-3-ylmethyl)piperazine
Show/Hide
|
C19H28N2O4
|
1
|
| 1 |
Ki = 323.59 nM
|
|
|
|
CP0115835
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-8-methylsulfonyl-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C20H31N3O5S
|
1
|
| 1 |
Ki = 363.08 nM
|
|
|
|
CP0949094
|
(S)-2-[((2-(2-methoxy-1-naphthoxy)ethyl)amino)methyl]-2,3,6,7,8,9-hexahydronaphtho[2,3-b][1,4]dioxine hydrochloride
Show/Hide
|
C26H30ClNO4
|
1
|
| 1 |
Ki = 371.54 nM
|
|
|
|
CP0404054
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-2,3-dihydro-1H-indol-7-yl)oxy]ethanamine;dihydrochloride
Show/Hide
|
C20H26Cl2N2O4
|
1
|
| 1 |
Ki = 371.54 nM
|
|
|
|
CP0396051
|
2-[2-[(6,6-diphenyl-1,4-dioxan-2-yl)methylamino]ethoxy]phenol
Show/Hide
|
C25H27NO4
|
1
|
| 1 |
Ki = 371.54 nM
|
|
|
|
CP0426667
|
1-[[(2R)-3,3-diphenyl-1,4-dioxan-2-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H32N2O3
|
1
|
| 1 |
Ki = 380.19 nM
|
|
|
|
CP0464374
|
N-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C18H27NO4
|
1
|
| 1 |
Ki = 389.05 nM
|
|
|
|
CP0453599
|
2-(2,6-dimethoxyphenoxy)-N-[[(3R)-2,3,6,7,8,9-hexahydrobenzo[g][1,4]benzodioxin-3-yl]methyl]ethanamine;hydrochloride
Show/Hide
|
C23H29NO5
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0943168
|
(R)-2-[((2-(2,6-Dimethoxyphenoxy)ethyl)amino)methyl]-8-hydroxy-1,4-benzodioxane hydrochloride
Show/Hide
|
C19H24ClNO6
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0468298
|
1-(1,4-dithiaspiro[4.5]decan-3-ylmethyl)-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C20H30N2OS2
|
1
|
| 1 |
Ki = 407.38 nM
|
|
|
|
CP0396500
|
N-[[(2S)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 416.87 nM
|
|
|
|
CP0485314
|
N-[[(3R)-2,3-dihydrobenzo[g][1,4]benzodioxin-3-yl]methyl]-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride
Show/Hide
|
C23H26ClNO5
|
1
|
| 1 |
Ki = 426.58 nM
|
|
|
|
CP0500270
|
N-(1-oxa-4-thiaspiro[4.5]decan-2-ylmethyl)-2-phenoxyethanamine
Show/Hide
|
C17H25NO2S
|
1
|
| 1 |
Ki = 436.52 nM
|
|
|
|
CP0373782
|
2-(3,5-dimethoxyphenoxy)-N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]ethanamine
Show/Hide
|
C26H29NO5
|
1
|
| 1 |
Ki = 446.68 nM
|
|
|
|
CP0892038
|
(S)-2-(2,6-dimethoxyphenoxy)-N-((5-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C20H26ClNO6
|
1
|
| 1 |
Ki = 446.68 nM
|
|
|
|
CP0121059
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8lambda4-thiaspiro[4.5]decane 8-oxide
Show/Hide
|
C19H28N2O4S
|
1
|
| 1 |
Ki = 478.63 nM
|
|
|
|
CP0155898
|
N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-1H-indol-7-yl)oxy]ethanamine
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
Ki = 489.78 nM
|
|
|
|
CP0512065
|
N-[[(3R)-2,3,6,7,8,9-hexahydrobenzo[g][1,4]benzodioxin-3-yl]methyl]-2-(2-methoxynaphthalen-1-yl)oxyethanamine;hydrochloride
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 549.54 nM
|
|
|
|
CP0522904
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-(2-methoxy-4-phenylphenoxy)ethanamine;hydrochloride
Show/Hide
|
C24H25NO4
|
1
|
| 1 |
Ki = 549.54 nM
|
|
|
|
CP0500278
|
N-(1,4-dithiaspiro[4.5]decan-3-ylmethyl)-2-phenoxyethanamine
Show/Hide
|
C17H25NOS2
|
1
|
| 1 |
Ki = 549.54 nM
|
|
|
|
CP0399906
|
N-[5-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C29H28ClN5O2
|
1
|
| 1 |
Ki = 562.34 nM
|
|
|
|
CP0889459
|
(S)-2-(2,6-dimethoxyphenoxy)-N-((2,3,6,7,8,9-hexahydronaphtho[2,3-b][1,4]dioxin-2-yl)methyl)ethanaminium chloride
Show/Hide
|
C23H30ClNO5
|
1
|
| 1 |
Ki = 575.44 nM
|
|
|
|
CP0388359
|
N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]phenyl]-4-phenylbenzamide
Show/Hide
|
C28H26ClN5O2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0860647
|
(R)-2-(2,6-dimethoxyphenoxy)-N-((5-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethanamine hydrochloride
Show/Hide
|
C20H26ClNO6
|
1
|
| 1 |
Ki = 645.65 nM
|
|
|
|
CP0714031
|
SID50105948
Show/Hide
|
C22H33Cl2N3O3
|
1
|
| 1 |
Ki = 707.95 nM
|
|
|
|
CP0232092
|
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C21H32N2O
|
1
|
| 1 |
Ki = 776.25 nM
|
|
|
|
CP0485217
|
3-[N'-(4,5-Dihydro-1H-imidazol-2-yl)-N-p-tolyl-hydrazino]-phenol
Show/Hide
|
C16H18N4O
|
1
|
| 1 |
Ki = 843 nM
|
|
|
|
CP0917489
|
(S)-N-((2,3-dihydronaphtho[2,3-b][1,4]dioxin-2-yl)methyl)-2-(2,6-dimethoxyphenoxy)ethanaminium chloride
Show/Hide
|
C23H26ClNO5
|
1
|
| 1 |
Ki = 891.25 nM
|
|
|
|
CP0379393
|
5-[(1aR,6R,6aR)-6-methoxy-1a,6-dihydro-1H-cyclopropa[a]inden-6a-yl]-1H-imidazole
Show/Hide
|
C14H14N2O
|
1
|
| 1 |
Ki = 912.01 nM
|
|
|
|
CP0468296
|
N-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)-2-phenoxyethanamine
Show/Hide
|
C17H25NO3
|
1
|
| 1 |
Ki = 977.24 nM
|
|
|
|
CP0131832
|
1-[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]ethanone
Show/Hide
|
C21H31N3O4
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0763927
|
2,2,2-Trifluoro-1-(2-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)ethan-1-one
Show/Hide
|
C21H28F3N3O4
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0775946
|
2-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane
Show/Hide
|
C24H32N4O3
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0444701
|
5,6-dichloro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)isoindoline-1,3-dione
Show/Hide
|
C27H31Cl2N3O3
|
1
|
| 1 |
Ki = 1082 nM
|
|
|
|
CP0388360
|
N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
|
C29H28ClN5O2
|
1
|
| 1 |
Ki = 1445.44 nM
|
|
|
|
CP0414234
|
2-(2,6-dimethoxyphenoxy)-N-[[(2S)-6,6-diphenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki = 1659.59 nM
|
|
|
|
CP0444051
|
N-[[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-2-[(6-methoxy-1H-indol-7-yl)oxy]ethanamine
Show/Hide
|
C20H22N2O4
|
1
|
| 1 |
Ki = 1905.46 nM
|
|
|
|
CP0379392
|
ATIPAMEZOLE
Show/Hide
|
C14H16N2
|
1
|
| 1 |
Ki = 1949.84 nM
|
|
|
|
CP0417233
|
FIPAMEZOLE
Show/Hide
|
C14H15FN2
|
1
|
| 1 |
Ki = 2089.3 nM
|
|
|
|
CP0350498
|
2-benzhydryloxy-3-(2-phenoxyethylamino)propan-1-ol;oxalic acid
Show/Hide
|
C26H29NO7
|
1
|
| 1 |
Ki = 2290.87 nM
|
|
|
|
CP0230607
|
N-(2-benzhydryloxyethyl)-2-(2-methoxyphenoxy)ethanamine;oxalic acid
Show/Hide
|
C26H29NO7
|
1
|
| 1 |
Ki = 3019.95 nM
|
|
|
|
CP0394915
|
4,5,6,7-tetrafluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)isoindoline-1,3-dione
Show/Hide
|
C27H29F4N3O3
|
1
|
| 1 |
Ki = 4108 nM
|
|
|
|
CP0135923
|
CHEBI:6956
Show/Hide
|
C23H30N2O4
|
1
|
| 1 |
Ki = 4770 nM
|
|
|
|
CP0037227
|
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C16H25NO
|
2
|
| 1 |
Ki > 1000 nM
|
|
|
| 2 |
Ki < 1000000 nM
|
|
|
|
CP0371704
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,5S)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374167
|
2-phenoxy-N-[[(2R,6S)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374168
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,6S)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0384754
|
2-phenoxy-N-[[(2R,5S)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0423054
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,5R)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0435760
|
2-phenoxy-N-[[(2R,5R)-5-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0439399
|
2-phenoxy-N-[[(2R,6R)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0439400
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,6R)-6-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373751
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(2-phenylphenoxy)ethanamine
Show/Hide
|
C30H29NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373752
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(4-phenylphenoxy)ethanamine
Show/Hide
|
C30H29NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0400292
|
N-[(2,2-diphenyl-1,3-dioxolan-4-yl)methyl]-2-(3-phenylphenoxy)ethanamine
Show/Hide
|
C30H29NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0854273
|
5-{[(2-Phenoxyethyl)amino]methyl}-2,2-diphenylcyclopentan-1-one Oxalate Salt
Show/Hide
|
C28H29NO6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0854277
|
5-({[2-(2-Methoxyphenoxy)ethyl]amino}methyl)-2,2-diphenylcyclopentan-1-one Oxalate Salt
Show/Hide
|
C29H31NO7
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0859496
|
cis-5-{[(2-Phenoxyethyl)amino]methyl}-2,2-diphenylcyclopentan-1-ol Oxalate Salt
Show/Hide
|
C28H31NO6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0500267
|
2-(2,6-dimethoxyphenoxy)-N-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)ethanamine
Show/Hide
|
C19H29NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402933
|
2-(2-methoxyphenoxy)-N-[[(2R,3S)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0416975
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,3R)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421814
|
N-[(3,3-diphenyl-1,4-dioxan-2-yl)methyl]-2-phenoxyethanamine
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421815
|
1-(2-methoxyphenyl)-4-[(2-phenyl-1,4-dioxan-2-yl)methyl]piperazine
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421816
|
1-(2-methoxyphenyl)-4-[[(2R,3S)-3-phenyl-1,4-dioxan-2-yl]methyl]piperazine
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421818
|
2-phenoxy-N-[(2-phenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421820
|
2-(2-methoxyphenoxy)-N-[(2-phenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421821
|
2-(2-methoxyphenoxy)-N-[[(2R,3R)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C20H25NO4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0434677
|
2-(2,6-dimethoxyphenoxy)-N-[(3,3-diphenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0434680
|
2-(2,6-dimethoxyphenoxy)-N-[(2-phenyl-1,4-dioxan-2-yl)methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0484174
|
2-phenoxy-N-[[(2R,3R)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0484175
|
2-phenoxy-N-[[(2R,3S)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C19H23NO3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0538009
|
2-(2,6-dimethoxyphenoxy)-N-[[(2R,3S)-3-phenyl-1,4-dioxan-2-yl]methyl]ethanamine
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0538010
|
1-(2-methoxyphenyl)-4-[[(2R,3R)-3-phenyl-1,4-dioxan-2-yl]methyl]piperazine
Show/Hide
|
C22H28N2O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0372320
|
3-[[2-(2,6-dimethoxyphenoxy)ethylamino]methyl]-2-phenyl-2,3-dihydrothiochromen-4-one
Show/Hide
|
C26H27NO4S
|
1
|
| 1 |
Ki < 1000000 nM
|
|
|
