Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[4-[[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]methyl]triazol-1-yl]-7-(diethylamino)chromen-2-one
    Show/Hide
 PubChem ID
CID: 122179431
Canonical SMILES
CCN(CC)c1ccc2cc(-n3cc(CN4CCN(CC4)c4nc(N)c5cc(OC)c(OC)cc5n4)nn3)c(=O)oc2c1
    Show/Hide
Compound Formula C30H35N9O4
Compound Structure
Protein Name
 Protein Info 
Alpha-1B adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P35368
Gene Name
ADRA1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 52.4 nM
   TI
   LI
   LO
   TS
2
Ki = 29.9 nM
   TI
   LI
   LO
   TS