Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT00864 , Vascular endothelial growth factor receptor 2
Gene Name KDR
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P35968
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT00864
 
Compound ID Compound Name Compound Formula
CP0113538
1-(3-Methylanilino)-4-(4-pyridylmethyl)phthalazine
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C21H18N4
 1
1
ED50 = 8 nM
   TI
   LI
   LO
   TS
CP0061266
1-(4-tert-Butylanilino)-4-(4-pyridylmethyl)phthalazine Dihydrochloride
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C24H24N4
 1
1
ED50 = 9 nM
   TI
   LI
   LO
   TS
CP0185264
1-(3,5-Dimethylanilino)-4-(4-pyridylmethyl)phthalazine
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C22H20N4
 1
1
ED50 = 10 nM
   TI
   LI
   LO
   TS
CP0062047
1-(3-Methoxy-4-chloroanilino)-4-(4-pyridylmethyl)-phthalazine
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C21H17ClN4O
 1
1
ED50 = 24 nM
   TI
   LI
   LO
   TS
CP0092595
1-(3,4-Dichloroanilino)-4-(4-pyridylmethyl)phthalazine
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C20H14Cl2N4
 1
1
ED50 = 27 nM
   TI
   LI
   LO
   TS
CP0123519
1-(3-Trifluormethyl-4-chloroanilino)-4-(4-pyridylmethyl)phthalazine
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C21H14ClF3N4
 1
1
ED50 = 27 nM
   TI
   LI
   LO
   TS
CP0660979
(4-Chloro-phenyl)-(4-pyridin-4-ylmethyl-phthalazin-1-yl)-amine; compound with succinic acid (CGP-79787D)
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C24H21ClN4O4
 2
1
ED50 = 34 nM
   TI
   LI
   LO
   TS
2
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0080353
1-(3-Methoxyanilino)-4-(4-pyridylmethyl)phthalazine
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C21H18N4O
 1
1
ED50 = 37 nM
   TI
   LI
   LO
   TS
CP0321597
1-(3-Trifluormethyl-5-bromoanilino)-4-(4-pyridylmethyl)phthalazine
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C21H14BrF3N4
 1
1
ED50 = 39 nM
   TI
   LI
   LO
   TS
CP0194479
1-(3-Trifluormethyl-5-fluoroanilino)-4-(4-pyridylmethyl)phthalazine
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C21H14F4N4
 1
1
ED50 = 40 nM
   TI
   LI
   LO
   TS
CP0123511
1-(4-Biphenylamino)-4-(4-pyridylmethyl)phthalazine
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C26H20N4
 1
1
ED50 = 85 nM
   TI
   LI
   LO
   TS
CP0045859
1-Anilino-4-(4-pyridylmethyl)phthalazine Dihydrochloride
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C20H16N4
 1
1
ED50 = 200 nM
   TI
   LI
   LO
   TS
CP0106002
1-(3-Hydroxyanilino)-4-(4-pyridylmethyl)phthalazine
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C20H16N4O
 1
1
ED50 = 250 nM
   TI
   LI
   LO
   TS
CP0008706
(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one
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C15H14N2O
 2
1
ED50 = 930 nM
   TI
   LI
   LO
   TS
2
IC50 = 884 nM
   TI
   LI
   LO
   TS
CP0245282
N-(3-isoquinolin-4-ylphenyl)-2-(pyridin-4-ylmethylamino)benzamide
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C28H22N4O
 1
1
IC50 = 1.16 nM
   TI
   LI
   LO
   TS
CP0037106
2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide
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C20H16F3N3O
 2
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.24 nM
   TI
   LI
   LO
   TS
CP0037980
(4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine
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C20H15ClN4
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0037988
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
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C22H24BrFN4O2
 1
1
IC50 = 2673 nM
   TI
   LI
   LO
   TS