Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide
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 PubChem ID
CID: 6398883
SID: 14877418
Canonical SMILES
FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
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Compound Formula C20H16F3N3O
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.24 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 90 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM
2 IC50 = 23 nM
3 IC50 = 31 nM
4 IC50 = 32 nM
5 IC50 = 39 nM
6 IC50 = 170 nM