| Compound ID |
Compound Name |
Compound Formula |
|
CP0177566
|
(4R)-4-methyl-6-[1-methyl-3-(1-methylpyrazol-4-yl)indazol-5-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one
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|
C22H22N6O
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
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CP0068059
|
(4R)-4-methyl-N-[3-(1,3-oxazol-5-yl)phenyl]-2-oxo-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide
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|
C20H18N4O3
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
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CP0099079
|
1-methyl-5-[(4R)-4-methyl-2-oxo-1,3,4,5-tetrahydro-1,5-benzodiazepin-6-yl]indazole-3-carboxamide
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|
C19H19N5O2
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
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CP0177567
|
(4R)-6-(3-cyclopropyl-1-methylindazol-5-yl)-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one
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|
C21H22N4O
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
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CP0231170
|
(4R)-4-methyl-6-[1-(1-phenylethyl)pyrazol-4-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one
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|
C21H22N4O
|
1
|
| 1 |
EC50 = 3400 nM
|
|
|
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CP0177568
|
(4R)-6-(3,4-dimethoxyphenyl)-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one
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|
C18H20N2O3
|
1
|
| 1 |
EC50 = 5000 nM
|
|
|
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CP0231171
|
1-methyl-5-[(4R)-4-methyl-2-oxo-1,3,4,5-tetrahydro-1,5-benzodiazepin-6-yl]indazole-3-carbonitrile
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|
C19H17N5O
|
1
|
| 1 |
EC50 = 7000 nM
|
|
|
|
CP0098924
|
(4R)-4-methyl-6-(1-methylindazol-5-yl)-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one
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|
C18H18N4O
|
1
|
| 1 |
EC50 = 8100 nM
|
|
|
|
CP0068060
|
(4R)-4-methyl-N-(1,3-oxazol-5-ylmethyl)-2-oxo-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide
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|
C15H16N4O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0098927
|
(4R)-N-(3,4-dihydro-2H-chromen-4-yl)-4-methyl-2-oxo-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide
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|
C20H21N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0223128
|
(4S)-4-methyl-6-[1-methyl-3-(1-methylpyrazol-4-yl)indazol-5-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one
Show/Hide
|
C22H22N6O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0231172
|
(4R)-4-methyl-2-oxo-N-[(1R)-1-phenylethyl]-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide
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|
C19H21N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0445084
|
(4R)-4-methyl-N-[(1R)-1-(1,3-oxazol-5-yl)propyl]-2-oxo-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide
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|
C17H20N4O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0474064
|
(4R)-4-methyl-6-(3-phenylmethoxyphenyl)-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one
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|
C23H22N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0573814
|
(4R)-4-methyl-2-oxo-N-[(1S)-1-phenylethyl]-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide
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|
C19H21N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0072530
|
3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N-methyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide
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|
C27H33F2N7O2
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0127942
|
1-[3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
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|
C27H32F2N6O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
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CP0548842
|
3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide
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|
C26H31F2N7O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
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CP0232265
|
1-[3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-[(3S)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
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|
C26H30F2N6O2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
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CP0562866
|
1-[3-[6-(1-methylpyrazol-4-yl)-7-(trifluoromethyl)-3,4-dihydro-2H-quinolin-1-yl]-1-[(3S)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
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|
C26H29F3N6O2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
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CP0364997
|
1-[3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-(1,1-dioxothian-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
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|
C27H32F2N6O3S
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0072531
|
1-[1-cyclohexyl-3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
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|
C28H34F2N6O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0558854
|
1-[3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-(1-methylsulfonylpiperidin-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
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|
C28H35F2N7O3S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
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CP0370048
|
1-[4-[5-acetyl-3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C29H35F2N7O2
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0072532
|
1-[3-[7-chloro-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-[(3S)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
Show/Hide
|
C25H29ClN6O2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
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CP0558856
|
1-[3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-(1-methylpiperidin-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
Show/Hide
|
C28H35F2N7O
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
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CP0370049
|
1-[3-[7-methyl-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-[(3S)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
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CP0327569
|
1-[3-[7-methoxy-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-[(3S)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
Show/Hide
|
C26H32N6O3
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
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CP0072533
|
1-[3-[6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-[(3S)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
Show/Hide
|
C25H30N6O2
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
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CP0086089
|
1-[3-[2-fluoro-4-(1-methylpyrazol-4-yl)anilino]-1-[(3S)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
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|
C22H25FN6O2
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
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CP0127939
|
3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N-ethyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide
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|
C28H35F2N7O2
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
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CP0470504
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1-[3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-piperidin-4-yl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone
Show/Hide
|
C27H33F2N7O
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
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CP0370050
|
3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N,N-dimethyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide
Show/Hide
|
C28H35F2N7O2
|
1
|
| 1 |
IC50 = 3700 nM
|
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