quinolinone, 40

quinolinone, 42

quinolinone, 43

N-(1,3-benzodioxol-5-ylmethyl)-2-[2-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)pyrrolidin-1-yl]-N-methylethanamine

N-(1,3-benzodioxol-5-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-(pyridin-3-ylmethyl)propane-1,3-diamine

N-(1,3-benzodioxol-5-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-(1,3-thiazol-2-ylmethyl)propane-1,3-diamine

N-(1,3-benzodioxol-5-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-methylpropane-1,3-diamine

N-(3-Chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-1-methyl-1H-imidazole-5-carboxamide

N-(1,3-benzodioxol-5-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-propylpropane-1,3-diamine

N-(1,3-benzodioxol-5-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-(thiophen-2-ylmethyl)propane-1,3-diamine

N-[2-(1,3-benzodioxol-5-yl)ethyl]-2-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)pyrrolidine-1-carboxamide

quinolinone, 12

N-(3-Chlorophenyl)-N-((7,8-difluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-4-methylnicotinamide

2-[3-(1,3-benzodioxol-5-ylmethylamino)propyl-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)amino]acetonitrile

1-[2-(1,3-benzodioxol-5-yl)ethyl]-3-[(2-imidazol-1-yl-6-methylpyrimidin-4-yl)methyl]urea

N-(1,3-benzodioxol-5-ylmethyl)-N'-(furan-2-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)propane-1,3-diamine

quinolinone, 24

isoquinoline N-oxide, 47

N-(1,3-benzodioxol-5-ylmethyl)-4-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)butan-1-amine

quinolinone, 44

N'-(1,3-benzodioxol-5-ylmethyl)-N-[1-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)ethyl]-N'-methylethane-1,2-diamine

2-(1,3-benzodioxol-5-ylmethylamino)-1-[2-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)pyrrolidin-1-yl]ethanone

ethyl 2-[3-(1,3-benzodioxol-5-ylmethylamino)propyl-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)amino]acetate

N-(1,3-benzodioxol-5-ylmethyl)-2-[2-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)pyrrolidin-1-yl]acetamide

4-[[3-(1,3-benzodioxol-5-ylmethylamino)propyl-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)amino]methyl]phenol

N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-methylpropane-1,3-diamine

quinolinone, 21

quinolinone, 18

quinolinone, 37

quinolinone, 15

N-(1,3-benzodioxol-5-ylmethyl)-N'-cyclopropyl-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)propane-1,3-diamine

2-[3-(1,3-benzodioxol-5-ylmethylamino)propyl-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)amino]-N-methylacetamide

quinolinone, 14

N-(1,3-benzodioxol-5-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-[(1-methylimidazol-4-yl)methyl]propane-1,3-diamine

2-[3-(1,3-benzodioxol-5-ylmethylamino)propyl-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)amino]-N,N-dimethylacetamide

2-[3-(1,3-benzodioxol-5-ylmethylamino)propyl-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)amino]acetamide

isoquinoline N-oxide, 34

7,8-difluoro-4-[[2-(2-methylpropyl)imidazo[4,5-b]pyrazin-3-yl]methyl]-1H-quinolin-2-one

quinolinone, 20

N-(1,3-benzodioxol-5-ylmethyl)-N'-(1-benzofuran-5-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)propane-1,3-diamine

4-[(2-cyclobutylimidazo[4,5-b]pyrazin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

quinolinone, 16

4-[[2-(3,3-difluorocyclobutyl)imidazo[4,5-b]pyrazin-3-yl]methyl]-7,8-difluoro-1H-quinolin-2-one

4-[[2-cyclobutyl-7-(trifluoromethyl)imidazo[4,5-b]pyridin-3-yl]methyl]-7,8-difluoro-1H-quinolin-2-one

quinolinone, 26

N-(1,3-benzodioxol-5-ylmethyl)-N'-[[4-(dimethylamino)phenyl]methyl]-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)propane-1,3-diamine

quinolinone, 35

4-[[2-cyclobutyl-7-(dimethylamino)imidazo[4,5-b]pyridin-3-yl]methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(2-cyclobutylimidazo[4,5-b]pyridin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(2-cyclobutylimidazo[4,5-b]pyrazin-3-yl)methyl]-8-fluoro-1H-quinolin-2-one

isoquinoline, 46

quinolinone, 10

4-[(2-cyclobutyl-7-methoxyimidazo[4,5-b]pyridin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[[2-(3,3-difluorocyclobutyl)imidazo[4,5-b]pyrazin-3-yl]methyl]-8-fluoro-1H-quinolin-2-one

N-[2-(1,3-benzodioxol-5-yl)ethyl]-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-methylpropane-1,3-diamine

quinolinone, 13

4-[(2-cyclobutylbenzimidazol-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(2-cyclobutyl-7-methylimidazo[4,5-b]pyridin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(7-chloro-2-cyclobutylimidazo[4,5-b]pyridin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(2-cyclopentylimidazo[4,5-b]pyrazin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

8-fluoro-4-[[2-(2-methylpropyl)imidazo[4,5-b]pyrazin-3-yl]methyl]-1H-quinolin-2-one

N-[2-(1,3-benzodioxol-5-ylmethoxy)ethyl]-1-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)ethanamine

2-(1,3-benzodioxol-5-ylmethylamino)-N-[(2-imidazol-1-yl-6-methylpyrimidin-4-yl)methyl]acetamide

quinolinone, 38

7,8-difluoro-4-[[2-(3-methylpyridin-4-yl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one

quinolinone, 19

N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N-[(4-methoxyphenyl)methyl]-N'-methylpropane-1,3-diamine

7,8-difluoro-4-[[2-(2-methylpropyl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one

quinolinone, 22

4-[(2-cyclobutylimidazo[4,5-c]pyridin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

quinolinone, 9

quinolinone, 39

4-[[2-(cyclobutylmethyl)benzimidazol-1-yl]methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(2-cyclobutylimidazo[4,5-b]pyridin-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[[2-(cyclopropylmethyl)benzimidazol-1-yl]methyl]-7,8-difluoro-1H-quinolin-2-one

7,8-difluoro-4-[(2-propylbenzimidazol-1-yl)methyl]-1H-quinolin-2-one

4-[(2-cyclopentylbenzimidazol-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

8-fluoroisoquinoline, 33

N-[(3,4-dimethoxyphenyl)methyl]-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-methylpropane-1,3-diamine

quinolinone, 25

7,8-difluoro-4-[(2-propan-2-ylbenzimidazol-1-yl)methyl]-1H-quinolin-2-one

difluorocoumarin, 45

7,8-difluoro-4-[(2-propan-2-ylimidazo[4,5-b]pyrazin-3-yl)methyl]-1H-quinolin-2-one

quinolinone, 17

quinolinone, 8

tetrahydroquinolinone, 28

quinolinone, 36

quinolinone, 7

7,8-difluoro-4-[[2-(3-methylbutyl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one

4-[(2-cyclopropylbenzimidazol-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[[2-(cyclopentylmethyl)benzimidazol-1-yl]methyl]-7,8-difluoro-1H-quinolin-2-one

7,8-difluoro-4-[[2-(4-methyl-1,3-thiazol-5-yl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one

N-(1,3-benzodioxol-5-ylmethyl)-2-[2-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)pyrrol-1-yl]-N-methylethanamine

coumarin, 29

7,8-difluoro-4-[(2-pyridin-4-ylbenzimidazol-1-yl)methyl]-1H-quinolin-2-one

N-(1,3-benzodioxol-5-ylmethyl)-N'-[2-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)propan-2-yl]ethane-1,2-diamine

8-fluoro-4-[[2-(4-methyl-1,3-thiazol-5-yl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one

N-(1,3-benzodioxol-5-ylmethyl)-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-(2H-tetrazol-5-ylmethyl)propane-1,3-diamine

4-[(2-ethylbenzimidazol-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

7,8-difluoro-4-[[2-(3-methylimidazol-4-yl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one

N-[3-[(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-methylamino]propyl]-1,3-benzodioxole-5-carboxamide

7,8-difluoro-4-[[2-(1,3-thiazol-5-yl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one

4-[(2-cyclohexylbenzimidazol-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

N-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-methylpropane-1,3-diamine

7,8-difluoro-4-[(2-pyridin-3-ylbenzimidazol-1-yl)methyl]-1H-quinolin-2-one

7,8-difluoro-4-[[2-(4-methylpyridin-3-yl)benzimidazol-1-yl]methyl]-1H-quinolin-2-one

quinolinone, 11

7,8-difluoro-4-[(2-pyridin-2-ylbenzimidazol-1-yl)methyl]-1H-quinolin-2-one

4-[(2-cyclobutylimidazo[4,5-c]pyridin-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(2-tert-butylbenzimidazol-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one

pyridinone, 27

quinoline, 30

quinolinone, 31

quinoline, 32

N-benzyl-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-methylpropane-1,3-diamine

N-[(3,4-difluorophenyl)methyl]-N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-methylpropane-1,3-diamine

N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N-(1H-indol-5-ylmethyl)-N'-methylpropane-1,3-diamine

N'-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)-N'-methyl-N-(pyridin-4-ylmethyl)propane-1,3-diamine

2-[3-(1,3-benzodioxol-5-ylmethylamino)propyl-(3-imidazol-1-yl-1,2,4-thiadiazol-5-yl)amino]acetic acid

N-[2-[1,3-benzodioxol-5-ylmethyl(methyl)amino]ethyl]-2-imidazol-1-yl-6-methylpyrimidine-4-carboxamide

4-[(3-chloro-N-pyrazin-2-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

7,8-difluoro-4-[[(2-methylphenyl)methyl-pyrazin-2-ylamino]methyl]-1H-quinolin-2-one

4-[(3-chloro-N-(1-methylpyrazolo[3,4-d]pyrimidin-4-yl)anilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[[(2-chlorophenyl)methyl-pyrazin-2-ylamino]methyl]-7,8-difluoro-1H-quinolin-2-one

7,8-difluoro-4-[[(2-fluorophenyl)methyl-pyrazin-2-ylamino]methyl]-1H-quinolin-2-one

4-[[benzyl(pyrazin-2-yl)amino]methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-pyrimidin-2-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-pyrimidin-4-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

N-(3-chlorophenyl)-N-[(7,8-difluoro-2-oxidoisoquinolin-2-ium-4-yl)methyl]pyrimidin-2-amine

4-[(3-chloro-N-[6-(dimethylamino)pyrimidin-4-yl]anilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-pyridin-2-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-(2-methylpyrimidin-4-yl)anilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-pyridazin-3-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-(6-methylpyrimidin-4-yl)anilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-(6-methoxypyrimidin-4-yl)anilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[[(4-chlorophenyl)methyl-pyrazin-2-ylamino]methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-pyridin-3-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

7,8-difluoro-4-[[pyrazin-2-yl(pyridin-2-ylmethyl)amino]methyl]-1H-quinolin-2-one

4-[(3-chloro-N-pyridin-4-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

N-(3-chlorophenyl)-N-[(7,8-difluoroisoquinolin-4-yl)methyl]pyrimidin-2-amine

4-[(3-chloro-N-pyrimidin-5-ylanilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[[(3-chlorophenyl)methyl-pyrazin-2-ylamino]methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-(3-methylpyridin-2-yl)anilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(3-chloro-N-[2-(dimethylamino)pyrimidin-4-yl]anilino)methyl]-7,8-difluoro-1H-quinolin-2-one

4-[(N-(3-chlorophenyl)anilino)methyl]-7,8-difluoro-1H-quinolin-2-one