Brief Information of the Compound and Protein
Compound Name
4-[(2-cyclobutylimidazo[4,5-b]pyridin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one
    Show/Hide
PubChem ID
CID: 25211376
SID: 57552930
Canonical SMILES
Fc1ccc2c(Cn3c(nc4cccnc34)C3CCC3)cc(=O)[nH]c2c1F
    Show/Hide
Compound Formula C20H16F2N4O
Compound Structure
Protein Name
Nitric oxide synthase, inducible
Protein Classification
Enzyme
Uniprot ID
P35228
Gene Name
NOS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 180 nM
   TI
   LI
   LO
   TS