General Information of the Compound
| Compound ID |
CP0458756
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| Compound Name |
4-[(2-cyclobutylimidazo[4,5-b]pyridin-1-yl)methyl]-7,8-difluoro-1H-quinolin-2-one
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| Structure |
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| Formula |
C20H16F2N4O
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| Molecular Weight |
366.371
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| Canonical SMILES |
Fc1ccc2c(Cn3c(nc4ncccc34)C3CCC3)cc(=O)[nH]c2c1F
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| InChI |
InChI=1S/C20H16F2N4O/c21-14-7-6-13-12(9-16(27)24-18(13)17(14)22)10-26-15-5-2-8-23-19(15)25-20(26)11-3-1-4-11/h2,5-9,11H,1,3-4,10H2,(H,24,27)
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| InChIKey |
BLYHNNQBGAYJIW-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01406, Nitric oxide synthase 1
Protein ID: PT01856, Nitric oxide synthase 3
Protein ID: PT01472, Nitric oxide synthase, inducible