Brief Information of the Compound and Protein
Compound Name
4-[(2-cyclobutylimidazo[4,5-b]pyrazin-3-yl)methyl]-7,8-difluoro-1H-quinolin-2-one
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PubChem ID
CID: 25211910
SID: 57553479
Canonical SMILES
Fc1ccc2c(Cn3c(nc4nccnc34)C3CCC3)cc(=O)[nH]c2c1F
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Compound Formula C19H15F2N5O
Compound Structure
Protein Name
Nitric oxide synthase, inducible
Protein Classification
Enzyme
Uniprot ID
P35228
Gene Name
NOS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 91 nM
   TI
   LI
   LO
   TS
2
IC50 = 91 nM
   TI
   LI
   LO
   TS