Brief Information of the Compound and Protein
Compound Name
7,8-difluoro-4-[(2-propan-2-ylimidazo[4,5-b]pyrazin-3-yl)methyl]-1H-quinolin-2-one
    Show/Hide
PubChem ID
CID: 49837065
SID: 103912772
Canonical SMILES
CC(C)c1nc2nccnc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12
    Show/Hide
Compound Formula C18H15F2N5O
Compound Structure
Protein Name
Nitric oxide synthase, inducible
Protein Classification
Enzyme
Uniprot ID
P35228
Gene Name
NOS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 850 nM
   TI
   LI
   LO
   TS