Compound ID |
Compound Name |
Compound Formula |
CP0559976
|
2-[2-[8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octylamino]ethyl]-7-methoxy-2-methyl-3,4-dihydrochromen-6-ol
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|
C34H46ClN3O3
|
3
|
1 |
IC50 = 0.12 nM
|
|
|
2 |
Ki = 0.132 nM
|
|
|
3 |
Ki = 0.258 nM
|
|
|
CP0553445
|
2-[2-[9-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]nonylamino]ethyl]-7-methoxy-2-methyl-3,4-dihydrochromen-6-ol
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|
C35H48ClN3O3
|
1
|
1 |
IC50 = 0.27 nM
|
|
|
CP0360381
|
N-(10-amino-12-fluoro-4-tetracyclo[8.3.1.18,12.02,7]pentadeca-2(7),3,5-trienyl)-4-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]butanamide
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|
C32H36ClFN4O
|
1
|
1 |
IC50 = 0.3 nM
|
|
|
CP0634716
|
1,9-bis(2-methyl-5H-2lamda4-pyrido[4,3-b]indol-5-yl)nonane diiodide
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|
C33H38I2N4
|
1
|
1 |
IC50 = 0.33 nM
|
|
|
CP0315615
|
2-[2-[7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptylamino]ethyl]-7-methoxy-2-methyl-3,4-dihydrochromen-6-ol
Show/Hide
|
C33H44ClN3O3
|
1
|
1 |
IC50 = 0.44 nM
|
|
|
CP0354722
|
5-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-(12-fluoro-10-tetracyclo[8.3.1.18,12.02,7]pentadeca-2,4,6-trienyl)pentanamide
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|
C33H37ClFN3O
|
1
|
1 |
IC50 = 1.3 nM
|
|
|
CP0204502
|
N-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)-N'-(12-fluoro-10-tetracyclo[8.3.1.18,12.02,7]pentadeca-2,4,6-trienyl)pentane-1,5-diamine
Show/Hide
|
C33H39ClFN3
|
1
|
1 |
IC50 = 1.4 nM
|
|
|
CP0354724
|
4-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]-N-(12-fluoro-10-tetracyclo[8.3.1.18,12.02,7]pentadeca-2,4,6-trienyl)butanamide
Show/Hide
|
C32H35ClFN3O
|
1
|
1 |
IC50 = 1.4 nM
|
|
|
CP0204503
|
N-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)-N'-(12-fluoro-10-tetracyclo[8.3.1.18,12.02,7]pentadeca-2,4,6-trienyl)butane-1,4-diamine
Show/Hide
|
C32H37ClFN3
|
1
|
1 |
IC50 = 2 nM
|
|
|
CP0553443
|
N-[9-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]nonyl]-2-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)acetamide
Show/Hide
|
C35H46ClN3O4
|
1
|
1 |
IC50 = 2.05 nM
|
|
|
CP0124543
|
N-(10-amino-12-fluoro-4-tetracyclo[8.3.1.18,12.02,7]pentadeca-2(7),3,5-trienyl)-5-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]pentanamide
Show/Hide
|
C33H38ClFN4O
|
1
|
1 |
IC50 = 2.5 nM
|
|
|
CP0364710
|
N-[8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl]-2-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)acetamide
Show/Hide
|
C34H44ClN3O4
|
1
|
1 |
IC50 = 3.69 nM
|
|
|
CP0574612
|
N-[6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)propanamide
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|
C33H42ClN3O4
|
1
|
1 |
IC50 = 3.8 nM
|
|
|
CP0001487
|
3,5-Dimethyl-adamantan-1-ylamine
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|
C12H21N
|
1
|
1 |
IC50 = 4.9 nM
|
|
|
CP0013001
|
(+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one
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|
C24H29NO3
|
6
|
1 |
IC50 = 5 nM
|
|
|
2 |
IC50 = 6.2 nM
|
|
|
3 |
IC50 = 9 nM
|
|
|
4 |
IC50 = 10 nM
|
|
|
5 |
IC50 = 16 nM
|
|
|
6 |
IC50 = 54 nM
|
|
|
CP0319318
|
N-[7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl]-2-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)acetamide
Show/Hide
|
C33H42ClN3O4
|
1
|
1 |
IC50 = 5.43 nM
|
|
|
CP0364708
|
N-[8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl]-3-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)propanamide
Show/Hide
|
C35H46ClN3O4
|
1
|
1 |
IC50 = 6.23 nM
|
|
|
CP0222166
|
[3-[[5-(5H-chromeno[2,3-b]pyridin-8-yloxy)pentyl-methylamino]methyl]phenyl] N-heptylcarbamate
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|
C33H43N3O4
|
1
|
1 |
IC50 = 6.92 nM
|
|
|
CP0363227
|
N-[7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl]-2-(7-methoxy-2-methyl-6-phenylmethoxy-3,4-dihydrochromen-2-yl)acetamide
Show/Hide
|
C40H48ClN3O4
|
1
|
1 |
IC50 = 6.99 nM
|
|
|
CP0555318
|
N-[9-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]nonyl]-2-(7-methoxy-2-methyl-6-phenylmethoxy-3,4-dihydrochromen-2-yl)acetamide
Show/Hide
|
C42H52ClN3O4
|
1
|
1 |
IC50 = 7.89 nM
|
|
|
CP0364709
|
N-[7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptyl]-3-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)propanamide
Show/Hide
|
C34H44ClN3O4
|
1
|
1 |
IC50 = 7.94 nM
|
|
|
CP0571560
|
2-[2-[2-[2-[2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethoxy]ethoxy]ethylamino]ethyl]-7-methoxy-2-methyl-3,4-dihydrochromen-6-ol
Show/Hide
|
C32H42ClN3O5
|
1
|
1 |
IC50 = 8.35 nM
|
|
|
CP0574433
|
N-[8-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]octyl]-2-(7-methoxy-2-methyl-6-phenylmethoxy-3,4-dihydrochromen-2-yl)acetamide
Show/Hide
|
C41H50ClN3O4
|
1
|
1 |
IC50 = 10.4 nM
|
|
|
CP0538786
|
N-[6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-2-(7-methoxy-2-methyl-6-phenylmethoxy-3,4-dihydrochromen-2-yl)acetamide
Show/Hide
|
C39H46ClN3O4
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0123718
|
[3-[[methyl-[5-(2-oxochromen-7-yl)oxypentyl]amino]methyl]phenyl] N-heptylcarbamate
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|
C30H40N2O5
|
1
|
1 |
IC50 = 11.3 nM
|
|
|
CP0150393
|
3-({methyl[3-({5-oxo-5H-chromeno[2,3-b]pyridin-8-yl}oxy)propyl]amino}methyl)phenyl N-heptylcarbamate hydrochloride
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|
C31H37N3O5
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0049496
|
6-chloro-1,2,3,4-tetrahydroacridin-9-amine
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|
C13H13ClN2
|
1
|
1 |
IC50 = 14.5 nM
|
|
|
CP0190276
|
[3-[[methyl-[5-[(6-oxo-7,8,9,10-tetrahydrobenzo[c]chromen-3-yl)oxy]pentyl]amino]methyl]phenyl] N-heptylcarbamate
Show/Hide
|
C34H46N2O5
|
1
|
1 |
IC50 = 18.3 nM
|
|
|
CP0100456
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-6-nitro-4-oxochromene-2-carboxamide
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|
C24H25N3O5
|
2
|
1 |
IC50 = 21 nM
|
|
|
2 |
Ki = 12 nM
|
|
|
CP0179236
|
[3-[[methyl-[3-[(6-oxo-7,8,9,10-tetrahydrobenzo[c]chromen-3-yl)oxy]propyl]amino]methyl]phenyl] N-heptylcarbamate
Show/Hide
|
C32H42N2O5
|
1
|
1 |
IC50 = 21.6 nM
|
|
|
CP0125846
|
N-[3-(1-benzylpiperidin-4-yl)propyl]-6-hydroxy-4-oxochromene-2-carboxamide
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|
C25H28N2O4
|
2
|
1 |
IC50 = 23 nM
|
|
|
2 |
Ki = 11 nM
|
|
|
CP0038042
|
(1S,9R,13E)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one
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|
C15H18N2O
|
1
|
1 |
IC50 = 29 nM
|
|
|
CP0065401
|
4-(1-benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-2-yl)methyl-prop-2-ynylamino]butanenitrile
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|
C29H32N4O
|
7
|
1 |
IC50 = 29 nM
|
|
|
2 |
Ki = 14.9 nM
|
|
|
3 |
Ki = 15 nM
|
|
|
4 |
Km = 368000 nM
|
|
|
5 |
Km = 622000 nM
|
|
|
6 |
Km = 936000 nM
|
|
|
7 |
Km = 955000 nM
|
|
|
CP0234147
|
4-[[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino]methyl]benzene-1,2-diol
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|
C26H33N3O2
|
1
|
1 |
IC50 = 29 nM
|
|
|
CP0202045
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-7-methoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C25H28N2O4
|
1
|
1 |
IC50 = 33 nM
|
|
|
CP0564565
|
3-(4-benzylpiperazin-1-yl)-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)propanamide
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|
C20H24N6O
|
1
|
1 |
IC50 = 34 nM
|
|
|
CP0314976
|
5-amino-4-(3-bromophenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
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|
C17H17BrN4S
|
2
|
1 |
IC50 = 37.3 nM
|
|
|
2 |
Ki = 147 nM
|
|
|
CP0123717
|
3-{[methyl({3-[(2-oxo-2H-chromen-7-yl)oxy]propyl})amino]methyl}phenyl N-heptylcarbamate hydrochloride
Show/Hide
|
C28H36N2O5
|
1
|
1 |
IC50 = 37.4 nM
|
|
|
CP0239687
|
6-amino-N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-oxochromene-2-carboxamide
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|
C24H27N3O3
|
2
|
1 |
IC50 = 41 nM
|
|
|
2 |
Ki = 62 nM
|
|
|
CP0136858
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-6,7-dimethoxy-4-oxochromene-2-carboxamide
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|
C26H30N2O5
|
2
|
1 |
IC50 = 46 nM
|
|
|
2 |
Ki = 39 nM
|
|
|
CP0553444
|
N-[2-[2-[2-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]ethoxy]ethoxy]ethyl]-2-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)acetamide
Show/Hide
|
C32H40ClN3O6
|
1
|
1 |
IC50 = 47.9 nM
|
|
|
CP0354805
|
2-(1-benzylpiperidin-4-yl)ethyl 6,7-dimethoxy-4-oxochromene-2-carboxylate
Show/Hide
|
C26H29NO6
|
2
|
1 |
IC50 = 56 nM
|
|
|
2 |
Ki = 11 nM
|
|
|
CP0580246
|
1-(7-nitro-1,2,3,4-tetrahydroacridin-9-yl)pyrazolo[3,4-b]pyridin-3-amine
Show/Hide
|
C19H16N6O2
|
1
|
1 |
IC50 = 56 nM
|
|
|
CP0513782
|
2-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)-N-[9-(1,2,3,4-tetrahydroacridin-9-ylamino)nonyl]acetamide
Show/Hide
|
C35H47N3O4
|
1
|
1 |
IC50 = 57.8 nM
|
|
|
CP0577107
|
4-(6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-yl)morpholine
Show/Hide
|
C19H24N2O3
|
1
|
1 |
IC50 = 62 nM
|
|
|
CP0552582
|
2-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)-N-[8-(1,2,3,4-tetrahydroacridin-9-ylamino)octyl]acetamide
Show/Hide
|
C34H45N3O4
|
1
|
1 |
IC50 = 69.8 nM
|
|
|
CP0635000
|
1,9-bis(5H-pyrido[4,3-b]indol-5-yl)nonane
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|
C31H32N4
|
1
|
1 |
IC50 = 80 nM
|
|
|
CP0181448
|
[3-[[methyl-[3-(4-methyl-2-oxochromen-7-yl)oxypropyl]amino]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C33H38N2O5
|
1
|
1 |
IC50 = 80.5 nM
|
|
|
CP0105896
|
[3-[[methyl-[5-(2-oxochromen-7-yl)oxypentyl]amino]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C34H40N2O5
|
1
|
1 |
IC50 = 88.1 nM
|
|
|
CP0145645
|
[3-[[methyl-[3-[(6-oxo-7,8,9,10-tetrahydrobenzo[c]chromen-3-yl)oxy]propyl]amino]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C36H42N2O5
|
1
|
1 |
IC50 = 89.9 nM
|
|
|
CP0325289
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-6-hydroxy-4-oxochromene-2-carboxamide
Show/Hide
|
C24H26N2O4
|
1
|
1 |
IC50 = 91 nM
|
|
|
CP0177123
|
4-[(1,2,3,4-tetrahydroacridin-9-ylamino)methyl]benzene-1,2-diol
Show/Hide
|
C20H20N2O2
|
1
|
1 |
IC50 = 100 nM
|
|
|
CP0222165
|
[3-[[methyl-[3-(2-oxochromen-7-yl)oxypropyl]amino]methyl]phenyl] N-(6-phenylhexyl)carbamate
Show/Hide
|
C33H38N2O5
|
1
|
1 |
IC50 = 109 nM
|
|
|
CP0144049
|
N-[3-(1-benzylpiperidin-4-yl)propyl]-6,7-dimethoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C27H32N2O5
|
2
|
1 |
IC50 = 110 nM
|
|
|
2 |
Ki = 21 nM
|
|
|
CP0176297
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-oxochromene-2-carboxamide
Show/Hide
|
C24H26N2O3
|
2
|
1 |
IC50 = 110 nM
|
|
|
2 |
Ki = 57 nM
|
|
|
CP0513783
|
2-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)-N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]acetamide
Show/Hide
|
C33H43N3O4
|
1
|
1 |
IC50 = 111 nM
|
|
|
CP0550484
|
7-methyl-9-piperidin-1-yl-1,2,3,4-tetrahydroacridine
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|
C19H24N2
|
1
|
1 |
IC50 = 118 nM
|
|
|
CP0350265
|
[3-[[methyl-[3-(2-oxo-3-phenylchromen-7-yl)oxypropyl]amino]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C38H40N2O5
|
1
|
1 |
IC50 = 125 nM
|
|
|
CP0001598
|
1,2,3,4-tetrahydro-9-acridinamine
Show/Hide
|
C13H14N2
|
8
|
1 |
IC50 = 130 nM
|
|
|
2 |
IC50 = 150 nM
|
|
|
3 |
IC50 = 190 nM
|
|
|
4 |
IC50 = 251.19 nM
|
|
|
5 |
IC50 = 320 nM
|
|
|
6 |
IC50 = 330 nM
|
|
|
7 |
IC50 = 374 nM
|
|
|
8 |
IC50 = 412 nM
|
|
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CP0574543
|
7-methyl-N-(2-morpholin-4-ylethyl)-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C20H27N3O
|
1
|
1 |
IC50 = 131 nM
|
|
|
CP0234142
|
4-[2-[5-(1,2,3,4-tetrahydroacridin-9-ylamino)pentoxy]ethyl]phenol
Show/Hide
|
C26H32N2O2
|
1
|
1 |
IC50 = 142 nM
|
|
|
CP0034617
|
(3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate; 2-hydroxybenzoic acid
Show/Hide
|
C15H21N3O2
|
2
|
1 |
IC50 = 160 nM
|
|
|
2 |
IC50 = 175 nM
|
|
|
CP0159912
|
N-[5-[2-(3,4-dimethoxyphenyl)ethoxy]pentyl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C28H36N2O3
|
1
|
1 |
IC50 = 168 nM
|
|
|
CP0202046
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-6-methoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C25H28N2O4
|
1
|
1 |
IC50 = 170 nM
|
|
|
CP0251487
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-6,7-dimethoxy-4-oxo-1H-quinoline-2-carboxamide
Show/Hide
|
C26H31N3O4
|
2
|
1 |
IC50 = 170 nM
|
|
|
2 |
Ki = 60 nM
|
|
|
CP0415531
|
[3-[[3-[3-(4-methoxyphenyl)-2-oxochromen-6-yl]oxypropyl-methylamino]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C39H42N2O6
|
1
|
1 |
IC50 = 179 nM
|
|
|
CP0564567
|
2-[(7-methyl-1,2,3,4-tetrahydroacridin-9-yl)amino]ethanol
Show/Hide
|
C16H20N2O
|
1
|
1 |
IC50 = 180 nM
|
|
|
CP0652533
|
(3-Dimethylcarbamoyloxy-phenyl)-trimethyl-ammonium bromide
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|
C12H19BrN2O2
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0094439
|
[4-[[4-[(2-oxochromen-7-yl)oxymethyl]triazol-1-yl]methyl]phenyl] N-heptylcarbamate
Show/Hide
|
C27H30N4O5
|
1
|
1 |
IC50 = 214 nM
|
|
|
CP0159950
|
N-[5-[2-(4-methoxyphenyl)ethoxy]pentyl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C27H34N2O2
|
1
|
1 |
IC50 = 216 nM
|
|
|
CP0550483
|
3-(4-phenylpiperazin-1-yl)-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)propanamide
Show/Hide
|
C19H22N6O
|
1
|
1 |
IC50 = 230 nM
|
|
|
CP0572915
|
9-(4-methylpiperazin-1-yl)-7-nitro-1,2,3,4-tetrahydroacridine
Show/Hide
|
C18H22N4O2
|
1
|
1 |
IC50 = 245 nM
|
|
|
CP0131365
|
[4-[[4-[(2-oxochromen-7-yl)oxymethyl]triazol-1-yl]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C31H30N4O5
|
1
|
1 |
IC50 = 255 nM
|
|
|
CP0552583
|
2-(6-hydroxy-7-methoxy-2-methyl-3,4-dihydrochromen-2-yl)-N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]acetamide
Show/Hide
|
C32H41N3O4
|
1
|
1 |
IC50 = 275 nM
|
|
|
CP0569699
|
3-morpholin-4-yl-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)propanamide
Show/Hide
|
C13H17N5O2
|
1
|
1 |
IC50 = 275 nM
|
|
|
CP0580068
|
7-nitro-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C19H16N6O2
|
1
|
1 |
IC50 = 299 nM
|
|
|
CP0125848
|
(1-benzylpiperidin-4-yl)methyl 6,7-dimethoxy-4-oxochromene-2-carboxylate
Show/Hide
|
C25H27NO6
|
1
|
1 |
IC50 = 300 nM
|
|
|
CP0249185
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-6-hydroxy-4-oxo-1H-quinoline-2-carboxamide
Show/Hide
|
C24H27N3O3
|
1
|
1 |
IC50 = 300 nM
|
|
|
CP0545515
|
2-(4-benzylpiperazin-1-yl)-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)acetamide
Show/Hide
|
C19H22N6O
|
1
|
1 |
IC50 = 301 nM
|
|
|
CP0578348
|
N-(9-piperidin-1-yl-5,6,7,8-tetrahydroacridin-2-yl)acetamide
Show/Hide
|
C20H25N3O
|
1
|
1 |
IC50 = 301 nM
|
|
|
CP0140793
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[3-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]propoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C28H32FN5O3S
|
1
|
1 |
IC50 = 310 nM
|
|
|
CP0324069
|
[3-[[3-[3-(4-methoxyphenyl)-2-oxochromen-7-yl]oxypropyl-methylamino]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C39H42N2O6
|
1
|
1 |
IC50 = 312 nM
|
|
|
CP0455243
|
2-(2-chlorophenyl)-1-(4-chlorophenyl)-5-ethyl-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]imidazole-4-carboxamide
Show/Hide
|
C35H35Cl2N5O
|
1
|
1 |
IC50 = 316.23 nM
|
|
|
CP0325288
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-5,7-dimethoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C26H30N2O5
|
1
|
1 |
IC50 = 320 nM
|
|
|
CP0179369
|
4-(1-benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-5-yl)methyl-prop-2-ynylamino]butanenitrile
Show/Hide
|
C29H32N4O
|
1
|
1 |
IC50 = 350 nM
|
|
|
CP0144048
|
N-[3-(1-benzylpiperidin-4-yl)propyl]-6-methoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C26H30N2O4
|
1
|
1 |
IC50 = 370 nM
|
|
|
CP0483865
|
4-[3-(1-benzylpiperidin-4-yl)propoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C28H33N5O3S
|
1
|
1 |
IC50 = 380 nM
|
|
|
CP0217023
|
[3-[[methyl-[3-(6-oxobenzo[c]chromen-3-yl)oxypropyl]amino]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C36H38N2O5
|
1
|
1 |
IC50 = 390 nM
|
|
|
CP0041761
|
2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol
Show/Hide
|
C28H27NO4S
|
1
|
1 |
IC50 = 400 nM
|
|
|
CP0552123
|
7-methyl-9-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydroacridine
Show/Hide
|
C19H25N3
|
1
|
1 |
IC50 = 440 nM
|
|
|
CP0100458
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-7-methoxy-4-oxo-1H-quinoline-2-carboxamide
Show/Hide
|
C25H29N3O3
|
1
|
1 |
IC50 = 450 nM
|
|
|
CP0159913
|
N-[5-[2-(4-phenylmethoxyphenyl)ethoxy]pentyl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C33H38N2O2
|
1
|
1 |
IC50 = 454 nM
|
|
|
CP0110416
|
ethyl (2R)-2-benzamido-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-5-oxopentanoate
Show/Hide
|
C28H37N3O4
|
1
|
1 |
IC50 = 500 nM
|
|
|
CP0177270
|
N-[5-[2-[3,4-bis(phenylmethoxy)phenyl]ethoxy]pentyl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C40H44N2O3
|
1
|
1 |
IC50 = 506 nM
|
|
|
CP0014240
|
3-(8-methylpyrido[4,3-b]indol-5-yl)-1-phenothiazin-10-ylpropan-1-one
Show/Hide
|
C27H21N3OS
|
1
|
1 |
IC50 = 510 nM
|
|
|
CP0089596
|
Prochelators, 2
Show/Hide
|
C17H19N3O2
|
1
|
1 |
IC50 = 520 nM
|
|
|
CP0580191
|
7-methyl-9-[4-(7-methyl-1,2,3,4-tetrahydroacridin-9-yl)piperazin-1-yl]-1,2,3,4-tetrahydroacridine
Show/Hide
|
C32H36N4
|
1
|
1 |
IC50 = 521 nM
|
|
|
CP0013002
|
3-(8-methoxypyrido[4,3-b]indol-5-yl)-1-phenothiazin-10-ylpropan-1-one
Show/Hide
|
C27H21N3O2S
|
1
|
1 |
IC50 = 540 nM
|
|
|
CP0159914
|
4-[2-[5-(1,2,3,4-tetrahydroacridin-9-ylamino)pentoxy]ethyl]benzene-1,2-diol
Show/Hide
|
C26H32N2O3
|
1
|
1 |
IC50 = 542 nM
|
|
|
CP0136859
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-5,7-dihydroxy-4-oxochromene-2-carboxamide
Show/Hide
|
C24H26N2O5
|
1
|
1 |
IC50 = 580 nM
|
|
|
CP0197578
|
4-(1,2,3,4-tetrahydroacridin-9-yliminomethyl)benzene-1,2-diol
Show/Hide
|
C20H18N2O2
|
1
|
1 |
IC50 = 609 nM
|
|
|
CP0422338
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-4,6,7-trimethoxyquinoline-2-carboxamide
Show/Hide
|
C27H33N3O4
|
1
|
1 |
IC50 = 620 nM
|
|
|
CP0570112
|
3-piperidin-1-yl-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)propanamide
Show/Hide
|
C14H19N5O
|
1
|
1 |
IC50 = 658 nM
|
|
|
CP0136869
|
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C24H26N2O5
|
1
|
1 |
IC50 = 660 nM
|
|
|
CP0123719
|
[3-[4-[(2-oxochromen-7-yl)oxymethyl]triazol-1-yl]phenyl] N-heptylcarbamate
Show/Hide
|
C26H28N4O5
|
1
|
1 |
IC50 = 702 nM
|
|
|
CP0140788
|
4-[2-(1-benzylpiperidin-4-yl)ethoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H31N5O3S
|
1
|
1 |
IC50 = 730 nM
|
|
|
CP0169981
|
13-(3-methoxyphenyl)-2-oxa-5,22-diazapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(22),3(12),4(9),5,7,10,14,16(21)-octaen-15-amine
Show/Hide
|
C26H23N3O2
|
2
|
1 |
IC50 = 750 nM
|
|
|
2 |
Ki = 870 nM
|
|
|
CP0110415
|
(2S)-2-benzamido-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-5-oxopentanoic acid
Show/Hide
|
C26H33N3O4
|
1
|
1 |
IC50 = 760 nM
|
|
|
CP0579063
|
N-(2-chloroethyl)-7-methyl-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C16H19ClN2
|
1
|
1 |
IC50 = 763 nM
|
|
|
CP0645546
|
SID56463133
Show/Hide
|
C20H18ClNO4
|
1
|
1 |
IC50 = 774 nM
|
|
|
CP0564566
|
7-methyl-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C20H19N5
|
1
|
1 |
IC50 = 811 nM
|
|
|
CP0569700
|
3-(4-methylpiperazin-1-yl)-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)propanamide
Show/Hide
|
C14H20N6O
|
1
|
1 |
IC50 = 844 nM
|
|
|
CP0513306
|
ethyl (2S)-2-benzamido-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-5-oxopentanoate
Show/Hide
|
C28H37N3O4
|
1
|
1 |
IC50 = 850 nM
|
|
|
CP0325290
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-5-methoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C25H28N2O4
|
1
|
1 |
IC50 = 870 nM
|
|
|
CP0076596
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-6-methoxy-4-oxo-1H-quinoline-2-carboxamide
Show/Hide
|
C25H29N3O3
|
1
|
1 |
IC50 = 880 nM
|
|
|
CP0270534
|
ethyl (2S)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-2-[(6-methoxynaphthalene-2-carbonyl)amino]-5-oxopentanoate
Show/Hide
|
C33H41N3O5
|
1
|
1 |
IC50 = 890 nM
|
|
|
CP0354461
|
hexyl (2R)-2-benzamido-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-5-oxopentanoate
Show/Hide
|
C32H45N3O4
|
1
|
1 |
IC50 = 890 nM
|
|
|
CP0329277
|
[3-[[3-[3-(4-chlorophenyl)-2-oxochromen-7-yl]oxypropyl-methylamino]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C38H39ClN2O5
|
1
|
1 |
IC50 = 900 nM
|
|
|
CP0518035
|
[3-[[4-[(2-oxochromen-7-yl)oxymethyl]triazol-1-yl]methyl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C31H30N4O5
|
1
|
1 |
IC50 = 922 nM
|
|
|
CP0354806
|
N-(1-benzylpiperidin-4-yl)-6-methoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C23H24N2O4
|
1
|
1 |
IC50 = 970 nM
|
|
|
CP0579595
|
7-methyl-N-[2-(4-methylpiperazin-1-yl)ethyl]-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C21H30N4
|
1
|
1 |
IC50 = 974 nM
|
|
|
CP0455171
|
4-Chloro-N-{[3-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazolyl]-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptylamino]-methylene}benzenesulfonamide
Show/Hide
|
C42H44Cl2N6O2S
|
1
|
1 |
IC50 = 1000 nM
|
|
|
CP0197580
|
5-(1,2,3,4-tetrahydroacridin-9-yliminomethyl)benzene-1,2,3-triol
Show/Hide
|
C20H18N2O3
|
1
|
1 |
IC50 = 1040 nM
|
|
|
CP0190277
|
[3-[[4-[(2-oxochromen-7-yl)oxymethyl]triazol-1-yl]methyl]phenyl] N-heptylcarbamate
Show/Hide
|
C27H30N4O5
|
1
|
1 |
IC50 = 1044 nM
|
|
|
CP0008951
|
3-(2,8-dimethylpyrido[4,3-b]indol-2-ium-5-yl)-1-phenothiazin-10-ylpropan-1-one;iodide
Show/Hide
|
C28H24IN3OS
|
1
|
1 |
IC50 = 1100 nM
|
|
|
CP0564568
|
N-(9-morpholin-4-yl-5,6,7,8-tetrahydroacridin-2-yl)acetamide
Show/Hide
|
C19H23N3O2
|
1
|
1 |
IC50 = 1110 nM
|
|
|
CP0239686
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-8-hydroxy-4-oxo-1H-quinoline-2-carboxamide
Show/Hide
|
C24H27N3O3
|
1
|
1 |
IC50 = 1150 nM
|
|
|
CP0000216
|
(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0^{1,12}.0^{6,17}]heptadeca-6,8,10(17),15-tetraen-14-ol
Show/Hide
|
C17H21NO3
|
1
|
1 |
IC50 = 1156 nM
|
|
|
CP0556843
|
[3-[4-[(2-oxochromen-7-yl)oxymethyl]triazol-1-yl]phenyl] N-(5-phenylpentyl)carbamate
Show/Hide
|
C30H28N4O5
|
1
|
1 |
IC50 = 1175 nM
|
|
|
CP0576783
|
4-(7-nitro-1,2,3,4-tetrahydroacridin-9-yl)morpholine
Show/Hide
|
C17H19N3O3
|
1
|
1 |
IC50 = 1217 nM
|
|
|
CP0457433
|
2-(2-chlorophenyl)-1-(4-chlorophenyl)-5-ethyl-N-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]imidazole-4-carboxamide
Show/Hide
|
C38H41Cl2N5O
|
1
|
1 |
IC50 = 1258.93 nM
|
|
|
CP0532243
|
2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[3-[1-[(2-fluorophenyl)methyl]piperidin-4-yl]propoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C28H32FN5O3S
|
1
|
1 |
IC50 = 1320 nM
|
|
|
CP0036542
|
(phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate
Show/Hide
|
C25H29N3O2
|
1
|
1 |
IC50 = 1344 nM
|
|
|
CP0202048
|
N-[(1-benzylpiperidin-4-yl)methyl]-6,7-dimethoxy-4-oxochromene-2-carboxamide
Show/Hide
|
C25H28N2O5
|
1
|
1 |
IC50 = 1460 nM
|
|
|
CP0234141
|
4-(1,2,3,4-tetrahydroacridin-9-yliminomethyl)phenol
Show/Hide
|
C20H18N2O
|
1
|
1 |
IC50 = 1475 nM
|
|
|
CP0065399
|
2-[[3-(1-benzylpiperidin-4-yl)propyl-prop-2-ynylamino]methyl]quinolin-8-ol
Show/Hide
|
C28H33N3O
|
1
|
1 |
IC50 = 1500 nM
|
|
|
CP0483866
|
4-[(1-benzylpiperidin-4-yl)methoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C26H29N5O3S
|
1
|
1 |
IC50 = 1500 nM
|
|
|
CP0359526
|
13-(4-methoxyphenyl)-2-oxa-5,22-diazapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(22),3(12),4(9),5,7,10,14,16(21)-octaen-15-amine
Show/Hide
|
C26H23N3O2
|
1
|
1 |
IC50 = 1510 nM
|
|
|
CP0136857
|
N-[2-(1-benzylpiperidin-4-yl)ethyl]-8-methoxy-4-oxo-1H-quinoline-2-carboxamide
Show/Hide
|
C25H29N3O3
|
1
|
1 |
IC50 = 1640 nM
|
|
|
CP0169982
|
13-phenyl-2-oxa-5,22-diazapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(22),3(12),4(9),5,7,10,14,16(21)-octaen-15-amine
Show/Hide
|
C25H21N3O
|
1
|
1 |
IC50 = 1730 nM
|
|
|
CP0578895
|
4-(7-methyl-1,2,3,4-tetrahydroacridin-9-yl)morpholine
Show/Hide
|
C18H22N2O
|
1
|
1 |
IC50 = 1775 nM
|
|
|
CP0076378
|
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
Show/Hide
|
C33H38N4O6
|
1
|
1 |
IC50 = 1827 nM
|
|
|
CP0545516
|
7-nitro-9-piperidin-1-yl-1,2,3,4-tetrahydroacridine
Show/Hide
|
C18H21N3O2
|
1
|
1 |
IC50 = 1885 nM
|
|
|
CP0354462
|
ethyl (2S)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-2-(1H-indole-3-carbonylamino)-5-oxopentanoate
Show/Hide
|
C30H38N4O4
|
1
|
1 |
IC50 = 1900 nM
|
|
|
CP0011456
|
8-fluoro-2-methyl-5H-pyrido[4,3-b]indol-2-ium;iodide
Show/Hide
|
C12H10FIN2
|
1
|
1 |
IC50 = 1900 nM
|
|
|
CP0578894
|
2-(4-phenylpiperazin-1-yl)-N-(2H-pyrazolo[3,4-b]pyridin-3-yl)acetamide
Show/Hide
|
C18H20N6O
|
1
|
1 |
IC50 = 1946 nM
|
|
|
CP0560241
|
13-(3-fluorophenyl)-2-oxa-5,22-diazapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(22),3(12),4(9),5,7,10,14,16(21)-octaen-15-amine
Show/Hide
|
C25H20FN3O
|
1
|
1 |
IC50 = 2200 nM
|
|
|
CP0013985
|
3-(2-methylpyrido[4,3-b]indol-2-ium-5-yl)-1-phenothiazin-10-ylpropan-1-one;iodide
Show/Hide
|
C27H22IN3OS
|
1
|
1 |
IC50 = 2200 nM
|
|
|
CP0014241
|
3-(2-benzylpyrido[4,3-b]indol-2-ium-5-yl)-1-phenothiazin-10-ylpropan-1-one;bromide
Show/Hide
|
C33H26BrN3OS
|
1
|
1 |
IC50 = 2200 nM
|
|
|
CP0666226
|
SID56463536
Show/Hide
|
C27H42ClNO2
|
1
|
1 |
IC50 = 2246 nM
|
|
|
CP0013006
|
1-phenothiazin-10-yl-3-pyrido[4,3-b]indol-5-ylpropan-1-one
Show/Hide
|
C26H19N3OS
|
1
|
1 |
IC50 = 2300 nM
|
|
|
CP0249187
|
N-(1-benzylpiperidin-4-yl)-6-hydroxy-4-oxochromene-2-carboxamide
Show/Hide
|
C22H22N2O4
|
1
|
1 |
IC50 = 2360 nM
|
|
|
CP0374126
|
4-Chloro-N-{[3-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazolyl][4-(1,2,3,4-tetrahydroacridin-9-ylamino)butylamino]methylene}benzenesulfonamide
Show/Hide
|
C39H38Cl2N6O2S
|
1
|
1 |
IC50 = 2511.89 nM
|
|
|
CP0576360
|
7-methyl-N-(2-piperidin-1-ylethyl)-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
|
C21H29N3
|
1
|
1 |
IC50 = 2542 nM
|
|
|
CP0013008
|
3-(8-fluoro-2-methylpyrido[4,3-b]indol-2-ium-5-yl)-1-phenothiazin-10-ylpropan-1-one;iodide
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C27H21FIN3OS
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1
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1 |
IC50 = 2600 nM
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CP0016322
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6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-methylbutyl)amine
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C23H30ClN3O
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1
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1 |
IC50 = 2667 nM
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CP0649397
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hexadecylpyridinium bromide
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C21H38BrN
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1
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1 |
IC50 = 2753 nM
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CP0381947
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N-methyl-N-[[1-methyl-5-[3-[1-[(2-methylphenyl)methyl]piperidin-4-yl]propoxy]indol-2-yl]methyl]prop-2-yn-1-amine
Show/Hide
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C30H39N3O
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1
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1 |
IC50 = 2800 nM
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CP0201877
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13-(4-methylphenyl)-2-oxa-5,22-diazapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(22),3(12),4(9),5,7,10,14,16(21)-octaen-15-amine
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C26H23N3O
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1
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1 |
IC50 = 2850 nM
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CP0064411
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N-[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamide
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C22H14Cl2I2N2O2
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1
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1 |
IC50 = 2951 nM
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CP0429989
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ethyl (4R)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-5-oxo-4-(phenylmethoxycarbonylamino)pentanoate
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C29H39N3O5
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1
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1 |
IC50 = 3000 nM
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CP0274102
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[3-[1-[(3-fluorophenyl)methyl]piperidin-4-yl]propoxy]-1,3-thiazole-5-carboxamide
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C28H32FN5O3S
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1
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1 |
IC50 = 3000 nM
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CP0048396
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HEXACHLOROPHENE
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C13H6Cl6O2
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1
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1 |
IC50 = 3014.9 nM
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CP0216973
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hexyl (2S)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-2-(1H-indole-3-carbonylamino)-5-oxopentanoate
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C34H46N4O4
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1
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1 |
IC50 = 3040 nM
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CP0393861
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5-amino-4-(3-methoxyphenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
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C18H20N4OS
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2
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1 |
IC50 = 3050 nM
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2 |
Ki = 3880 nM
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CP0140154
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3-(1-benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-2-yl)methyl-prop-2-ynylamino]propanenitrile
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C28H30N4O
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1
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1 |
IC50 = 3300 nM
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CP0673695
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N-{[5-(3-(1-Benzylpiperidin-4-yl)propoxy)-1-methyl-1Hindol-2-yl]methyl}-N-methylprop-2-yn-1-amine
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C29H37N3O
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1
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1 |
IC50 = 3400 nM
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CP0567455
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N-hydroxy-N-[(1S)-1-methylsulfanyl-2-[5-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]benzotriazol-1-yl]ethyl]formamide
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C23H25N5O3S
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1
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1 |
IC50 = 3500 nM
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CP0518733
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N-[(1-benzylpiperidin-4-yl)methyl]-6-methoxy-4-oxochromene-2-carboxamide
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C24H26N2O4
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1
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1 |
IC50 = 3610 nM
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CP0251448
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4-[2-[1-[(2-chlorophenyl)methyl]piperidin-4-yl]ethoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-1,3-thiazole-5-carboxamide
Show/Hide
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C27H30ClN5O3S
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1
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1 |
IC50 = 3700 nM
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CP0196546
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[3-[[methyl-[3-(2-oxochromen-7-yl)oxypropyl]amino]methyl]phenyl] N-(4-hexylphenyl)carbamate
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C33H38N2O5
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1
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1 |
IC50 = 3800 nM
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CP0072054
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2-[[2-(1-benzylpiperidin-4-yl)ethyl-prop-2-ynylamino]methyl]quinolin-8-ol
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C27H31N3O
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1
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1 |
IC50 = 4100 nM
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CP0076597
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N-[2-(1-benzylpiperidin-4-yl)ethyl]-6,7-dihydroxy-4-oxochromene-2-carboxamide
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C24H26N2O5
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1
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1 |
IC50 = 4130 nM
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CP0049360
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(S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate
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C14H22N2O2
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1
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1 |
IC50 = 4450 nM
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CP0225240
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
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C27H30FN5O3S
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1
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1 |
IC50 = 4500 nM
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CP0441705
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N-[[5-[3-(1-benzylpiperidin-4-yl)propoxy]-1H-indol-2-yl]methyl]prop-2-en-1-amine
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C27H35N3O
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1
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1 |
IC50 = 4600 nM
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CP0094206
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CHEBI:7825
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C18H13Cl4N3O
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1
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1 |
IC50 = 4646.5 nM
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CP0225242
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(3-fluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
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C27H30FN5O3S
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1
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1 |
IC50 = 4700 nM
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CP0381952
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N-[[5-[3-(1-benzylpiperidin-4-yl)propoxy]-1H-indol-2-yl]methyl]prop-2-yn-1-amine
Show/Hide
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C27H33N3O
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1
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1 |
IC50 = 4900 nM
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CP0216972
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ethyl (4S)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-5-oxo-4-(phenylmethoxycarbonylamino)pentanoate
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C29H39N3O5
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1
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1 |
IC50 = 4990 nM
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CP0219667
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5-amino-4-(4-chlorophenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
Show/Hide
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C17H17ClN4S
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1
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1 |
IC50 = 5280 nM
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CP0011747
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3-(8-methoxy-2-methylpyrido[4,3-b]indol-2-ium-5-yl)-1-phenothiazin-10-ylpropan-1-one;iodide
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C28H24IN3O2S
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1
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1 |
IC50 = 5300 nM
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CP0671760
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Nizatidine
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C12H21N5O2S2
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1
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1 |
IC50 = 5614.6 nM
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CP0659761
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{4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride
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C25H30ClN3
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1
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1 |
IC50 = 5847 nM
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CP0558215
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-4-[[1-[(3-nitrophenyl)methyl]piperidin-4-yl]methoxy]-1,3-thiazole-5-carboxamide
Show/Hide
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C27H30N6O5S
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1
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1 |
IC50 = 6000 nM
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CP0011919
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3-(8-fluoropyrido[4,3-b]indol-5-yl)-1-phenothiazin-10-ylpropan-1-one
Show/Hide
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C26H18FN3OS
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1
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1 |
IC50 = 6200 nM
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CP0552124
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N-[2-(4-benzylpiperazin-1-yl)ethyl]-7-methyl-1,2,3,4-tetrahydroacridin-9-amine
Show/Hide
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C27H34N4
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1
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1 |
IC50 = 6381 nM
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CP0566647
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(2S)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-2-(1H-indole-3-carbonylamino)-5-oxopentanoic acid
Show/Hide
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C28H34N4O4
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1
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1 |
IC50 = 6400 nM
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CP0708528
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1-(5-(4-(4-Methylpiperazin-1-yl)phenyl)-3-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
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C24H30N4O3
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2
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1 |
IC50 = 6500 nM
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2 |
Ki = 630 nM
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CP0671644
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Ethylestrenol
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C20H32O
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1
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1 |
IC50 = 6504 nM
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CP0352701
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-(pyridin-2-ylmethyl)piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
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C26H30N6O3S
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1
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1 |
IC50 = 6600 nM
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CP0065934
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BUTENAFINE
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C23H27N
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1
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1 |
IC50 = 6907.1 nM
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CP0071426
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1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piperidin-1-yl]butan-1-one
Show/Hide
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C32H39NO2
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1
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1 |
IC50 = 7479.9 nM
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CP0457780
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(1-benzylpiperidin-4-yl)methyl 6-methoxy-4-oxochromene-2-carboxylate
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C24H25NO5
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1
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1 |
IC50 = 7490 nM
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CP0144776
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5-amino-4-(4-methoxyphenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
Show/Hide
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C18H20N4OS
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1
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1 |
IC50 = 7640 nM
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CP0251449
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(2-fluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
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C27H30FN5O3S
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1
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1 |
IC50 = 7800 nM
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CP0011455
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3-(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)-1-phenothiazin-10-ylpropan-1-one
Show/Hide
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C27H25N3OS
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1
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1 |
IC50 = 7800 nM
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CP0274100
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4-[(1-benzylpiperidin-4-yl)methoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
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C27H31N5O3S
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1
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1 |
IC50 = 8000 nM
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CP0081600
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5-amino-4-(1,3-benzodioxol-5-yl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
Show/Hide
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C18H18N4O2S
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1
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1 |
IC50 = 8180 nM
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CP0441704
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[5-[[4-[3-[1-methyl-2-[[methyl(prop-2-ynyl)amino]methyl]indol-5-yl]oxypropyl]piperidin-1-yl]methyl]quinolin-8-yl] N,N-dimethylcarbamate
Show/Hide
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C35H43N5O3
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1
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1 |
IC50 = 8400 nM
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CP0008457
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2-benzyl-5H-pyrido[4,3-b]indol-2-ium;bromide
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C18H15BrN2
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1
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1 |
IC50 = 8600 nM
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CP0015007
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2-methylpyrido[4,3-b]indole;hydroiodide
Show/Hide
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C12H11IN2
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1
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1 |
IC50 = 8700 nM
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CP0349316
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[[1-[(2-fluorophenyl)methyl]piperidin-4-yl]methoxy]-N-methyl-1,3-thiazole-5-carboxamide
Show/Hide
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C27H30FN5O3S
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1
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1 |
IC50 = 9000 nM
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CP0014375
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2,8-dimethyl-5H-pyrido[4,3-b]indol-2-ium;iodide
Show/Hide
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C13H13IN2
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1
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1 |
IC50 = 9100 nM
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CP0441703
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ethyl 5-[3-(1-benzylpiperidin-4-yl)propoxy]-1H-indole-2-carboxylate
Show/Hide
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C26H32N2O3
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1
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1 |
IC50 = 9600 nM
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CP0072055
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2-[[(1-benzylpiperidin-4-yl)methyl-prop-2-ynylamino]methyl]quinolin-8-ol
Show/Hide
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C26H29N3O
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1
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1 |
IC50 = 9700 nM
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CP0314485
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diethyl (2S)-2-(phenylmethoxycarbonylamino)pentanedioate
Show/Hide
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C17H23NO6
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1
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1 |
IC50 > 10000 nM
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CP0533277
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diethyl (2R)-2-(phenylmethoxycarbonylamino)pentanedioate
Show/Hide
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C17H23NO6
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1
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1 |
IC50 > 10000 nM
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CP0164988
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5-amino-4-(3-methylphenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
Show/Hide
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C18H20N4S
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1
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1 |
IC50 = 10100 nM
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CP0246166
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5-amino-4-phenyl-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
Show/Hide
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C17H18N4S
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1
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1 |
IC50 = 10800 nM
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CP0003556
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8-fluoro-5H-pyrido[4,3-b]indole
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C11H7FN2
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1
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1 |
IC50 = 11400 nM
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CP0069723
|
4-octylphenol
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C14H22O
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1
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1 |
IC50 = 11471 nM
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CP0672512
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4-nitro-N-(2-oxo-2H-chromen-3-yl)benzamide
Show/Hide
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C16H10N2O5
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1
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1 |
IC50 = 12890 nM
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CP0400673
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[5-[3-(1-benzylpiperidin-4-yl)propoxy]-1H-indol-2-yl]methanol
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C24H30N2O2
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1
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1 |
IC50 = 13600 nM
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CP0057530
|
ECONAZOLE
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C18H15Cl3N2O
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1
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1 |
IC50 = 13677 nM
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CP0008946
|
8-methoxy-2-methyl-5H-pyrido[4,3-b]indol-2-ium;iodide
Show/Hide
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C13H13IN2O
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1
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1 |
IC50 = 14700 nM
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CP0574636
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N-hydroxy-N-[(1S)-2-[5-[2-[4-[2-(hydroxymethyl)imidazol-1-yl]phenyl]ethynyl]benzotriazol-1-yl]-1-methylsulfanylethyl]formamide
Show/Hide
|
C22H20N6O3S
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1
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1 |
IC50 = 15000 nM
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CP0839912
|
3-(3',4'-Dichlorobenzamide)coumarin
Show/Hide
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C16H9Cl2NO3
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1
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1 |
IC50 = 15010 nM
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CP0037303
|
ADD-3878
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C18H23NO3S
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1
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1 |
IC50 = 15026 nM
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CP0553682
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(2S)-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-2-[(6-methoxynaphthalene-2-carbonyl)amino]-5-oxopentanoic acid
Show/Hide
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C31H37N3O5
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1
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1 |
IC50 = 15200 nM
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CP0400674
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N-[[5-[3-(1-benzylpiperidin-4-yl)propoxy]-1H-indol-2-yl]methyl]-N-methylprop-2-yn-1-amine
Show/Hide
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C28H35N3O
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1
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1 |
IC50 = 15400 nM
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CP0076778
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2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
Show/Hide
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C20H21ClO4
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1
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1 |
IC50 = 15551 nM
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CP0011920
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2-benzyl-8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indole
Show/Hide
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C18H17FN2
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1
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1 |
IC50 = 17600 nM
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CP0576359
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2-(4-benzylpiperazin-1-yl)-N-[2-[2-oxo-2-[[2-[2-oxo-2-(2H-pyrazolo[3,4-b]pyridin-3-ylamino)ethyl]pyrazolo[3,4-b]pyridin-3-yl]amino]ethyl]pyrazolo[3,4-b]pyridin-3-yl]acetamide
Show/Hide
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C35H34N14O3
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1
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1 |
IC50 = 18040 nM
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CP0218567
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4-methyl-N-(2-oxidanylidenechromen-3-yl)benzamide
Show/Hide
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C17H13NO3
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1
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1 |
IC50 = 18380 nM
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CP0063077
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1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid
Show/Hide
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C18H14Cl4N2O
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1
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1 |
IC50 = 18659 nM
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CP0693253
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4-chloro-N-(2-oxo-2H-chromen-3-yl)benzamide
Show/Hide
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C16H10ClNO3
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1
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1 |
IC50 = 18710 nM
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CP0030899
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1-[(2-chlorophenyl)-diphenylmethyl]imidazole
Show/Hide
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C22H17ClN2
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1
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1 |
IC50 = 19410 nM
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CP0225239
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(2,6-difluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H29F2N5O3S
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1
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1 |
IC50 = 19500 nM
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CP0349985
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(2R)-2-benzamido-5-[2-(1-benzylpiperidin-4-yl)ethylamino]-5-oxopentanoic acid
Show/Hide
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C26H33N3O4
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1
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1 |
IC50 = 20000 nM
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CP0701539
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1-(5-(4-(4-Benzylpiperidin-1-yl)phenyl)-3-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C31H35N3O3
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1
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1 |
IC50 = 20100 nM
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CP0014374
|
2-benzyl-1,3,4,5-tetrahydropyrido[4,3-b]indole
Show/Hide
|
C18H18N2
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1
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1 |
IC50 = 20400 nM
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CP0008459
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5H-Pyrido[4,3-B]Indole
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C11H8N2
|
1
|
1 |
IC50 = 21400 nM
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CP0066208
|
Fungistat
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C26H31Cl2N5O3
|
1
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1 |
IC50 = 21573 nM
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CP0551773
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N-[(1S)-2-[5-[2-[4-[(3S,4S)-3,4-dihydroxypyrrolidin-1-yl]phenyl]ethynyl]benzotriazol-1-yl]-1-methylsulfanylethyl]-N-hydroxyformamide
Show/Hide
|
C22H23N5O4S
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1
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1 |
IC50 = 22000 nM
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CP0065937
|
US9138393, Methyl- cholanthrene
Show/Hide
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C21H16
|
1
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1 |
IC50 = 22683 nM
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CP0314975
|
5-amino-4-(4-methylphenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
Show/Hide
|
C18H20N4S
|
1
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1 |
IC50 = 23800 nM
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CP0481349
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5-amino-4-[4-(dimethylamino)phenyl]-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
Show/Hide
|
C19H23N5S
|
1
|
1 |
IC50 = 24100 nM
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CP0780699
|
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide monohydrochloride
Show/Hide
|
C22H22Cl4N4O
|
1
|
1 |
IC50 = 25118.86 nM
|
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CP0042711
|
4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
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C18H20O2
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1
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1 |
IC50 = 25550 nM
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CP0085428
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(B(a)P)
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C20H12
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1
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1 |
IC50 = 28000 nM
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CP0513481
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5-amino-4-(3-nitrophenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
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C17H17N5O2S
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1
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1 |
IC50 = 29800 nM
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CP0325524
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5-amino-4-(4-fluorophenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
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C17H17FN4S
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1
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1 |
IC50 = 31000 nM
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CP0246167
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5-amino-4-(2-methoxyphenyl)-3,4,6,7,8,9-hexahydro-1H-pyrimido[4,5-b]quinoline-2-thione
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C18H20N4OS
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1
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1 |
IC50 = 31200 nM
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CP0374128
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1-(4-Chlorophenyl)-2-(2-chlorophenyl)-5-ethyl-N-(piperidin-1-yl)-1H-imidazole-4-carboxamide
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C23H24Cl2N4O
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1
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1 |
IC50 > 31622.78 nM
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CP0261321
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N-hydroxy-N-[(1S)-1-methylsulfanyl-2-[5-[2-[4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)phenyl]ethynyl]benzotriazol-1-yl]ethyl]formamide
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C23H23N5O3S
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1
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1 |
IC50 = 32000 nM
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CP0013743
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2-benzyl-8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indole
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C19H20N2
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1
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1 |
IC50 = 35100 nM
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CP0014242
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8-methyl-5H-pyrido[4,3-b]indole
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C12H10N2
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1
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1 |
IC50 = 35400 nM
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CP0742410
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4-methyl-N-(6-methyl-2-oxo-2H-chromen-3-yl)benzamide
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C18H15NO3
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1
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1 |
IC50 = 41370 nM
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CP0558272
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[2-[1-[(3,4-difluorophenyl)methyl]piperidin-4-yl]ethoxy]-1,3-thiazole-5-carboxamide
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C27H29F2N5O3S
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1
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1 |
IC50 = 42800 nM
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CP0308748
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[4-[4-[(2-oxochromen-7-yl)oxymethyl]triazol-1-yl]phenyl] N-(5-phenylpentyl)carbamate
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C30H28N4O5
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1
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1 |
IC50 = 47900 nM
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CP0714083
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1-(5-(4-(4-Ethylpiperazin-1-yl)phenyl)-3-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
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C25H32N4O3
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1
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1 |
IC50 = 47900 nM
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CP0015006
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8-methoxy-5H-pyrido[4,3-b]indole
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C12H10N2O
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1
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1 |
IC50 = 49600 nM
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CP0011921
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2-benzyl-8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole
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C19H20N2O
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1
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1 |
IC50 = 52700 nM
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CP0836294
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1-(5-(4-(4-Benzylpiperazin-1-yl)phenyl)-3-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
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C30H34N4O3
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1
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1 |
IC50 = 62800 nM
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CP0065400
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2-(1-benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-2-yl)methyl-prop-2-ynylamino]acetonitrile
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C27H28N4O
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1
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1 |
IC50 = 64200 nM
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CP0672501
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4-methoxy-N-(2-oxo-2H-chromen-3-yl)benzamide
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C17H13NO4
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1
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1 |
IC50 = 69470 nM
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CP0495532
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4-(1-benzylpiperidin-4-yl)oxy-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
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C26H29N5O3S
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1
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1 |
IC50 = 73000 nM
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CP0748445
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1-(5-(4-(4-Methylpiperidin-1-yl)phenyl)-3-(3,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
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C25H31N3O3
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1
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1 |
IC50 = 77400 nM
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CP0274098
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[[1-[(3,4-difluorophenyl)methyl]piperidin-4-yl]methoxy]-N-methyl-1,3-thiazole-5-carboxamide
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C27H29F2N5O3S
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1
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1 |
IC50 = 80000 nM
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CP0274096
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4-[[1-[(4-chlorophenyl)methyl]piperidin-4-yl]methoxy]-2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-N-methyl-1,3-thiazole-5-carboxamide
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C27H30ClN5O3S
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1
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1 |
IC50 = 82000 nM
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CP0483864
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2-[2-(cyclopropanecarbonylamino)pyridin-4-yl]-4-[[1-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]methoxy]-N-methyl-1,3-thiazole-5-carboxamide
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C27H29Cl2N5O3S
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1
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1 |
IC50 = 97000 nM
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CP0537149
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N-hydroxy-N-[(1S)-1-methylsulfanyl-2-[5-[2-[4-(2-oxo-2lambda4-thia-6-azaspiro[3.3]heptan-6-yl)phenyl]ethynyl]benzotriazol-1-yl]ethyl]formamide
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C23H23N5O3S2
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1
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1 |
IC50 > 100000 nM
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