Brief Information of the Compound and Protein
Compound Name
4-(1-benzylpiperidin-4-yl)-2-[(8-hydroxyquinolin-2-yl)methyl-prop-2-ynylamino]butanenitrile
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PubChem ID
CID: 134132255
Canonical SMILES
Oc1cccc2ccc(CN(CC#C)C(CCC3CCN(Cc4ccccc4)CC3)C#N)nc12
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Compound Formula C29H32N4O
Compound Structure
Protein Name
Acetylcholinesterase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P22303
Gene Name
ACHE
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  7
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
Ki = 14.9 nM
   TI
   LI
   LO
   TS
3
Ki = 15 nM
   TI
   LI
   LO
   TS
4
Km = 368000 nM
   TI
   LI
   LO
   TS
5
Km = 622000 nM
   TI
   LI
   LO
   TS
6
Km = 936000 nM
   TI
   LI
   LO
   TS
7
Km = 955000 nM
   TI
   LI
   LO
   TS