General Information of the Compound
Compound ID
CP0659761
Compound Name
{4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride
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Synonyms
548-62-9
Adergon
Aniline Violet
Atmonil
Avermin
Axuris
Badil
Basic Violet BN
Basic violet 3
Bismuth Violet
Brilliant Violet 5B
Calcozine Violet 6BN
Calcozine Violet C
Crystal Violet O
Crystal violet
Gentersal
Gentian violet
Gentiaverm
Genticid
Gentioletten
Hecto Violet R
Hexamethyl Violet
Hexamethylpararosaniline chloride
Meroxyl-Wander
Meroxylan-Wander
Methyl Violet 10B
Methylrosaniline chloride
Oxiuran
Oxycolor
Oxyozyl
Paper Blue R
Pyoktanin
Vermicid
Vianin
Viocid
Violet CP
gentian violet
methylrosanilinium chloride
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Structure
Formula
C25H30ClN3
Molecular Weight
407.989
Canonical SMILES
CN(C)c1ccc(C(=C2C=CC(=[N+](C)C)C=C2)c2ccc(N(C)C)cc2)cc1.[Cl-]
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InChI
InChI=1S/C25H30N3.ClH/c1-26(2)22-13-7-19(8-14-22)25(20-9-15-23(16-10-20)27(3)4)21-11-17-24(18-12-21)28(5)6;/h7-18H,1-6H3;1H/q+1;/p-1
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InChIKey
ZXJXZNDDNMQXFV-UHFFFAOYSA-M
CAS
7077-31-8
23355-47-7
548-62-9
Physicochemical Property
logP
1.4636
Rotatable Bonds
4
Heavy Atom Count
29
Polar Areas
9.49
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11057
SID: 14928660
ChEMBL ID
CHEMBL64894
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00820, Acetylcholinesterase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 5847 nM
   TI
   LI
   LO
   TS
Protein ID: PT00817, Cytochrome P450 2D6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 824.4 nM
   TI
   LI
   LO
   TS
Protein ID: PT00986, Cytochrome P450 3A4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 3633.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Potency = 10000 nM
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 5309.1 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( Gentian violet )
Drug Name Gentian violet
Indication
Bacterial infection
Approved