General Information of the Compound
Compound ID
CP0181448
Compound Name
[3-[[methyl-[3-(4-methyl-2-oxochromen-7-yl)oxypropyl]amino]methyl]phenyl] N-(5-phenylpentyl)carbamate
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Structure
Formula
C33H38N2O5
Molecular Weight
542.676
Canonical SMILES
CN(CCCOc1ccc2c(C)cc(=O)oc2c1)Cc1cccc(OC(=O)NCCCCCc2ccccc2)c1
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InChI
InChI=1S/C33H38N2O5/c1-25-21-32(36)40-31-23-28(16-17-30(25)31)38-20-10-19-35(2)24-27-14-9-15-29(22-27)39-33(37)34-18-8-4-7-13-26-11-5-3-6-12-26/h3,5-6,9,11-12,14-17,21-23H,4,7-8,10,13,18-20,24H2,1-2H3,(H,34,37)
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InChIKey
RIRAXUJPOGFDFJ-UHFFFAOYSA-N
Physicochemical Property
logP
6.50372
Rotatable Bonds
14
Heavy Atom Count
40
Polar Areas
81.01
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 127045292
ChEMBL ID
CHEMBL3828259
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00820, Acetylcholinesterase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 80.5 nM
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