Brief Information of the Compound and Protein
Compound Name
[(2S)-2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate
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PubChem ID
CID: 11452022
SID: 16551051
Canonical SMILES
CCCCCCCCc1ccc(CC[C@](N)(CO)COP(O)(O)=O)cc1
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Compound Formula C19H34NO5P
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 3
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
Q99500
Gene Name
S1PR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
EC50 = 27 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
2
EC50 = 27 nM
   TI
   LI
   LO
   TS
CL000194 RBL-1 Rattus norvegicus (Rat)  1
1
EC50 = 5.012 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 94 nM
   TI
   LI
   LO
   TS