| Compound ID |
Compound Name |
Compound Formula |
|
CP0447460
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C29H27ClF2N2O2S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0478571
|
2-[(2,6-difluorophenyl)methylsulfanyl]-7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C29H27F3N2O2S
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0458693
|
2-[(3,5-difluoropyridin-4-yl)methylsulfanyl]-7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C28H26F3N3O2S
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0536097
|
(7S)-2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H25ClF2N2O2S
|
1
|
| 1 |
EC50 = 73 nM
|
|
|
|
CP0478577
|
4-[[7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazol-2-yl]sulfanylmethyl]-3,5-difluorobenzoic acid
Show/Hide
|
C30H27F3N2O4S
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
|
CP0399008
|
7-(4-chloro-3-methoxyphenyl)-1-(4-fluorophenyl)-7-methyl-2-(pyrimidin-2-ylmethylsulfanyl)-5,6-dihydro-4H-benzimidazole
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|
C26H24ClFN4OS
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0536099
|
2-[2-[2-[4-[[7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazol-2-yl]sulfanylmethyl]-3,5-difluorophenoxy]ethoxy]ethoxy]-N,N-dimethylethanamine
Show/Hide
|
C37H44F3N3O5S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0487795
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H25ClF2N2O2S
|
1
|
| 1 |
EC50 = 125 nM
|
|
|
|
CP0420365
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazole
Show/Hide
|
C25H21ClF2N2O2S2
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0517806
|
4-[[7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazol-2-yl]sulfanylmethyl]-3,5-difluoro-N-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]benzamide
Show/Hide
|
C38H44F3N3O7S
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0482105
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-4-(4-fluoro-3-methoxyphenyl)-3-(4-fluorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]imidazole
Show/Hide
|
C26H20ClF3N2O2S
|
1
|
| 1 |
EC50 = 214 nM
|
|
|
|
CP0447648
|
4-[[5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazol-2-yl]sulfanylmethyl]-3,5-difluorobenzonitrile
Show/Hide
|
C26H20F3N3O2S2
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0413092
|
7-(4-fluoro-3-methoxyphenyl)-1-(4-fluorophenyl)-7-methyl-2-(pyrimidin-2-ylmethylsulfanyl)-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C26H24F2N4OS
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0533946
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-fluoro-3-methoxyphenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H24Cl2F2N2O2S
|
1
|
| 1 |
EC50 = 313 nM
|
|
|
|
CP0569600
|
2-[4-[[7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazol-2-yl]sulfanylmethyl]-3,5-difluorophenyl]ethanol
Show/Hide
|
C31H31F3N2O3S
|
1
|
| 1 |
EC50 = 321 nM
|
|
|
|
CP0406644
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-4-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]imidazole
Show/Hide
|
C27H23ClF2N2O3S
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0387231
|
2-[[4-[[5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazol-2-yl]sulfanylmethyl]-3,5-difluorobenzoyl]amino]ethanesulfonic acid
Show/Hide
|
C28H26F3N3O6S3
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0561760
|
7-(4-chloro-3-methoxyphenyl)-2-[(2-fluoro-6-nitrophenyl)methylsulfanyl]-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22ClF2N3O3S
|
1
|
| 1 |
EC50 = 397 nM
|
|
|
|
CP0458691
|
2-[2-[2-[4-[[7-(4-chloro-3-methoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazol-2-yl]sulfanylmethyl]-3,5-difluorophenoxy]ethoxy]ethoxy]-N,N-dimethylethanamine
Show/Hide
|
C36H41ClF3N3O4S
|
1
|
| 1 |
EC50 = 460 nM
|
|
|
|
CP0406643
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-fluoro-3-methylphenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H24Cl2F2N2OS
|
1
|
| 1 |
EC50 = 490 nM
|
|
|
|
CP0482114
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(3,4-difluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H21Cl2F3N2OS
|
1
|
| 1 |
EC50 = 509 nM
|
|
|
|
CP0478578
|
7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-7-methyl-2-(pyrimidin-2-ylmethylsulfanyl)-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C27H27FN4O2S
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0413093
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-fluoro-3-methoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22ClF3N2OS
|
1
|
| 1 |
EC50 = 550 nM
|
|
|
|
CP0406645
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C28H24Cl2F2N2OS
|
1
|
| 1 |
EC50 = 560 nM
|
|
|
|
CP0565500
|
N'-[4-[[5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazol-2-yl]sulfanylmethyl]-3,5-difluorophenyl]sulfonyl-N,N-dimethylmethanimidamide
Show/Hide
|
C28H27F3N4O4S3
|
1
|
| 1 |
EC50 = 590 nM
|
|
|
|
CP0413088
|
2-[(2-bromo-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22BrClF2N2OS
|
1
|
| 1 |
EC50 = 621 nM
|
|
|
|
CP0517835
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-fluoro-3-methoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C28H24ClF3N2OS
|
1
|
| 1 |
EC50 = 678 nM
|
|
|
|
CP0482112
|
2-[2-[2-[3-[[7-(4-chloro-3-methoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazol-2-yl]sulfanylmethyl]-2,4-difluorophenoxy]ethoxy]ethoxy]-N,N-dimethylethanamine
Show/Hide
|
C36H41ClF3N3O4S
|
1
|
| 1 |
EC50 = 680 nM
|
|
|
|
CP0393993
|
7-(4-chloro-3-methoxyphenyl)-2-[(2,6-difluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22ClF3N2OS
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0405617
|
5-(diaminomethylideneamino)-2-[[4-[[5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazol-2-yl]sulfanylmethyl]-3,5-difluorobenzoyl]amino]pentanoic acid
Show/Hide
|
C32H33F3N6O5S2
|
1
|
| 1 |
EC50 = 760 nM
|
|
|
|
CP0458711
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-4-(4-chloro-3-methoxyphenyl)-3-(4-fluorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]imidazole
Show/Hide
|
C26H20Cl2F2N2O2S
|
1
|
| 1 |
EC50 = 778 nM
|
|
|
|
CP0458696
|
1-(3-chloro-4-fluorophenyl)-2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H21Cl3F2N2OS
|
1
|
| 1 |
EC50 = 812 nM
|
|
|
|
CP0510972
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22Cl2F2N2OS
|
1
|
| 1 |
EC50 = 890 nM
|
|
|
|
CP0447650
|
N-[[2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-3-(4-fluorophenyl)imidazol-4-yl]methyl]-N-(3,4-dimethoxyphenyl)formamide
Show/Hide
|
C26H22ClF2N3O3S
|
1
|
| 1 |
EC50 = 990 nM
|
|
|
|
CP0507150
|
2-[2-[2-[3,5-difluoro-4-[[7-(4-fluoro-3-methoxyphenyl)-1-(4-fluorophenyl)-7-methyl-5,6-dihydro-4H-benzimidazol-2-yl]sulfanylmethyl]phenoxy]ethoxy]ethoxy]-N,N-dimethylethanamine
Show/Hide
|
C36H41F4N3O4S
|
1
|
| 1 |
EC50 = 1090 nM
|
|
|
|
CP0406647
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(2,4-difluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H21Cl2F3N2OS
|
1
|
| 1 |
EC50 = 1340 nM
|
|
|
|
CP0487796
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(3-chloro-4-methoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22Cl2F2N2OS
|
1
|
| 1 |
EC50 = 1510 nM
|
|
|
|
CP0565487
|
5-[4-[[5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazol-2-yl]sulfanylmethyl]-3,5-difluorophenyl]-2H-tetrazole
Show/Hide
|
C26H21F3N6O2S2
|
1
|
| 1 |
EC50 = 2060 nM
|
|
|
|
CP0902135
|
4-[[(5-[[(3,4-Dimethoxyphenyl)sulfanyl]methyl]-1-(4-fluorophenyl)-1H-imidazol-2-yl)sulfanyl]methyl]-3,5-difluoro-N-[2-(trimethylamino)ethyl]benzamide hydrochloride
Show/Hide
|
C31H34ClF3N4O3S2
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0482113
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)-7-(3-methoxyphenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H23ClF2N2OS
|
1
|
| 1 |
EC50 = 2780 nM
|
|
|
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CP0458694
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H23ClF2N2O2S
|
1
|
| 1 |
EC50 = 2930 nM
|
|
|
|
CP0478575
|
7-(4-chloro-3-methoxyphenyl)-2-[(2-fluoro-6-methoxyphenyl)methylsulfanyl]-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H25ClF2N2O2S
|
1
|
| 1 |
EC50 = 4810 nM
|
|
|
|
CP0387233
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-5-[(3,4-dimethoxyphenoxy)methyl]-1-(4-fluorophenyl)imidazole
Show/Hide
|
C25H21ClF2N2O3S
|
1
|
| 1 |
EC50 = 5680 nM
|
|
|
|
CP0407891
|
4-[[5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazol-2-yl]sulfanylmethyl]-3,5-difluorobenzoic acid
Show/Hide
|
C26H21F3N2O4S2
|
1
|
| 1 |
EC50 = 6080 nM
|
|
|
|
CP0406646
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-7-(fluoromethyl)-1-(4-fluorophenyl)-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C28H23Cl2F3N2OS
|
1
|
| 1 |
EC50 = 6200 nM
|
|
|
|
CP0413090
|
7-(4-chloro-3-methoxyphenyl)-2-[(2,5-difluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22ClF3N2OS
|
1
|
| 1 |
EC50 = 7415 nM
|
|
|
|
CP0874122
|
4-[[(5-[[(3,4-Dimethoxyphenyl)sulfanyl]methyl]-1-(4-fluorophenyl)-1H-imidazol-2-yl)sulfanyl]methyl]-3,5-difluoro-N-[3-(trimethylazaniumyl)propyl]benzene-1-sulfonamide trifluoroacetate
Show/Hide
|
C33H36F6N4O6S3
|
1
|
| 1 |
EC50 = 9360 nM
|
|
|
|
CP0413094
|
(7R)-2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(3,4-dimethoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H25ClF2N2O2S
|
1
|
| 1 |
EC50 = 9390 nM
|
|
|
|
CP0862079
|
[3-[N-(2-hydroxyethyl)(4-[[(5-[[(3,4-dimethoxyphenyl)sulfanyl]methyl]-1-(4-fluorophenyl)-1H-imidazol-2-yl)sulfanyl]methyl]-3,5-difluorobenzene)sulfonamido]propyl]trimethylazanium trifluoroacetate
Show/Hide
|
C36H42F6N4O7S3
|
1
|
| 1 |
EC50 = 11750 nM
|
|
|
|
CP0457303
|
[2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-4-(4-chloro-3-methoxyphenyl)-3-(4-fluorophenyl)-6,7-dihydro-5H-benzimidazol-4-yl]methanol
Show/Hide
|
C28H24Cl2F2N2O2S
|
1
|
| 1 |
EC50 = 12500 nM
|
|
|
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CP0482115
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H21Cl2F5N2OS
|
1
|
| 1 |
EC50 = 13400 nM
|
|
|
|
CP0536098
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-chlorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22Cl3FN2OS
|
1
|
| 1 |
EC50 = 18550 nM
|
|
|
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CP0510973
|
7-(1,3-benzodioxol-5-yl)-2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H21ClF2N2O2S
|
1
|
| 1 |
EC50 = 26000 nM
|
|
|
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CP0478576
|
7-(4-chloro-3-methoxyphenyl)-2-[(2,4-difluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22ClF3N2OS
|
1
|
| 1 |
EC50 = 26440 nM
|
|
|
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CP0476693
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-methoxyphenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C28H25Cl2FN2O2S
|
1
|
| 1 |
EC50 = 38160 nM
|
|
|
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CP0429573
|
4-[[5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazol-2-yl]sulfinylmethyl]-3,5-difluorobenzoic acid
Show/Hide
|
C26H21F3N2O5S2
|
1
|
| 1 |
EC50 = 44900 nM
|
|
|
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CP0413091
|
2-[(3-chloro-5-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
Show/Hide
|
C27H22Cl2F2N2OS
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
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CP0429048
|
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-7-ethyl-1-(4-fluorophenyl)-5,6-dihydro-4H-benzimidazole
Show/Hide
|
C29H26Cl2F2N2OS
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
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CP0387229
|
N-[[2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-3-(4-fluorophenyl)imidazol-4-yl]methyl]-N-(3,4-dimethoxyphenyl)acetamide
Show/Hide
|
C27H24ClF2N3O3S
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
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CP0447651
|
N-[[2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-3-(4-fluorophenyl)imidazol-4-yl]methyl]-3,4-dimethoxyaniline
Show/Hide
|
C25H22ClF2N3O2S
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
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CP0851682
|
4-[[(5-[[(3,4-dimethoxyphenyl)sulfanyl]methyl]-1-(4-fluorophenyl)-1H-imidazol-2-yl)sulfanyl]methyl]-3,5-difluoro-N,N-bis[3-(trimethylazaniumyl)propyl]benzene 1-sulfonamide bis(trifluoroacetate)
Show/Hide
|
C41H50F9N5O8S3
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
