Brief Information of the Compound and Protein
Compound Name
7-(4-chloro-3-methoxyphenyl)-2-[(2,5-difluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
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PubChem ID
CID: 118464628
Canonical SMILES
COc1cc(ccc1Cl)C1CCCc2nc(SCc3cc(F)ccc3F)n(c12)-c1ccc(F)cc1
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Compound Formula C27H22ClF3N2OS
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q80SS6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000851 STC 1 Homo sapiens (Human)  1
1
EC50 = 7415 nM
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   LI
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   TS