Brief Information of the Compound and Protein
Compound Name
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-4-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-6,7-dihydro-4H-pyrano[3,4-d]imidazole
    Show/Hide
PubChem ID
CID: 118464724
Canonical SMILES
COc1ccc(cc1OC)C1OCCc2nc(SCc3c(F)cccc3Cl)n(c12)-c1ccc(F)cc1
    Show/Hide
Compound Formula C27H23ClF2N2O3S
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Steroid-like ligand receptor
Uniprot ID
Q80SS6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000851 STC 1 Homo sapiens (Human)  1
1
EC50 = 330 nM
   TI
   LI
   LO
   TS