| Compound ID |
Compound Name |
Compound Formula |
|
CP0537930
|
1-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]-2,2,2-trifluoroethanol
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|
C22H20F5N5O2
|
1
|
| 1 |
IC50 = 28.4 nM
|
|
|
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CP0356937
|
2-[4-[[4-(1-cyclopropyl-3-phenylpyrazol-4-yl)oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
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|
C25H25N5O2
|
1
|
| 1 |
IC50 = 28.9 nM
|
|
|
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CP0356942
|
2-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
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|
C23H25F2N5O2
|
1
|
| 1 |
IC50 = 42.5 nM
|
|
|
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CP0192486
|
3-ethenyl-6-[2-(6-methylpyridin-2-yl)pyrazol-3-yl]quinazolin-4-one
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|
C19H15N5O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
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CP0356958
|
N-[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]-2-morpholin-4-ylpyridin-4-amine
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|
C24H26F2N6O2
|
1
|
| 1 |
IC50 = 45.3 nM
|
|
|
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CP0160302
|
6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-cyclopenta[c]pyrazol-3-yl]-3H-quinazolin-4-one
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|
C20H17N5O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0293898
|
6-[4-ethyl-2-(6-methylpyridin-2-yl)pyrazol-3-yl]-3H-quinazolin-4-one
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|
C19H17N5O
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0537931
|
1-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]-4,4-difluorocyclohexan-1-ol
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|
C26H27F4N5O2
|
1
|
| 1 |
IC50 = 57.1 nM
|
|
|
|
CP0073726
|
6-[4-methyl-2-(6-methylpyridin-2-yl)pyrazol-3-yl]-3H-quinazolin-4-one
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|
C18H15N5O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0504215
|
6-[2-(6-methylpyridin-2-yl)pyrazol-3-yl]-3H-quinazolin-4-one
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|
C17H13N5O
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0362921
|
Ly-3200882
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|
C24H29N5O3
|
1
|
| 1 |
IC50 = 82.9 nM
|
|
|
|
CP0558057
|
2-[4-[[4-[1-cyclopropyl-3-(4,4-difluorocyclohexyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
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|
C25H29F2N5O2
|
1
|
| 1 |
IC50 = 86.5 nM
|
|
|
|
CP0356957
|
2-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]-1,1,1-trifluoropropan-2-ol
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|
C23H22F5N5O2
|
1
|
| 1 |
IC50 = 90.2 nM
|
|
|
|
CP0534635
|
2-[4-[[4-[3-(1,3-benzodioxol-5-yl)-1-cyclopropylpyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
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|
C26H25N5O4
|
1
|
| 1 |
IC50 = 91.9 nM
|
|
|
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CP0356940
|
3-[1-cyclopropyl-4-[2-[[2-(2-hydroxypropan-2-yl)pyridin-4-yl]amino]pyridin-4-yl]oxypyrazol-3-yl]-1-(trifluoromethyl)cyclobutan-1-ol
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|
C24H26F3N5O3
|
1
|
| 1 |
IC50 = 102 nM
|
|
|
|
CP0269281
|
4-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]oxan-4-ol
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|
C25H27F2N5O3
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0362918
|
2-[4-[[4-[1-cyclopropyl-3-(3-oxabicyclo[3.1.0]hexan-6-yl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
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|
C24H27N5O3
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0362920
|
3-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]-1-(2,2,2-trifluoroethyl)azetidin-3-ol
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|
C25H25F5N6O2
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0572154
|
2-[4-[[4-[1-cyclopropyl-3-(4-fluorophenyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
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|
C25H24FN5O2
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
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CP0362919
|
1-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]-4-(trifluoromethyl)piperidin-4-ol
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|
C26H27F5N6O2
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
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CP0356941
|
3-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]oxetan-3-ol
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|
C23H23F2N5O3
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
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CP0504214
|
3-methyl-6-[4-methyl-2-(6-methylpyridin-2-yl)pyrazol-3-yl]quinazolin-4-one
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|
C19H17N5O
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0425116
|
4-[1-cyclopropyl-4-[2-[[2-(2-hydroxypropan-2-yl)pyridin-4-yl]amino]pyridin-4-yl]oxypyrazol-3-yl]-1-methylcyclohexan-1-ol
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|
C26H33N5O3
|
1
|
| 1 |
IC50 = 136 nM
|
|
|
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CP0425186
|
4-[1-cyclopropyl-4-[2-[[2-(2-hydroxypropan-2-yl)pyridin-4-yl]amino]pyridin-4-yl]oxypyrazol-3-yl]benzonitrile
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|
C26H24N6O2
|
1
|
| 1 |
IC50 = 162 nM
|
|
|
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CP0537929
|
2-[4-[[4-[1-cyclopropyl-3-(1-methylpyrazol-4-yl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
Show/Hide
|
C23H25N7O2
|
1
|
| 1 |
IC50 = 188 nM
|
|
|
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CP0073727
|
3-methyl-6-[2-(6-methylpyridin-2-yl)pyrazol-3-yl]quinazolin-4-one
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|
C18H15N5O
|
1
|
| 1 |
IC50 = 211 nM
|
|
|
|
CP0425187
|
2-[4-[[4-[1-cyclopropyl-3-(2,3-dihydro-1,4-benzodioxin-5-yl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
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|
C27H27N5O4
|
1
|
| 1 |
IC50 = 225 nM
|
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|
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CP0549120
|
6-[5-ethyl-2-(6-methylpyridin-2-yl)pyrazol-3-yl]-3-methylquinazolin-4-one
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|
C20H19N5O
|
1
|
| 1 |
IC50 = 274 nM
|
|
|
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CP0356959
|
cyclopropyl-[6-[4-[[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]-6-hydroxy-2-azaspiro[3.3]heptan-2-yl]methanone
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|
C30H32F2N6O3
|
1
|
| 1 |
IC50 = 283 nM
|
|
|
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CP0269279
|
2-[4-[[4-(1-cyclopropyl-3-pyridin-4-ylpyrazol-4-yl)oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
Show/Hide
|
C24H24N6O2
|
1
|
| 1 |
IC50 = 326 nM
|
|
|
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CP0323115
|
3-methyl-6-[5-methyl-2-(6-methylpyridin-2-yl)pyrazol-3-yl]quinazolin-4-one
Show/Hide
|
C19H17N5O
|
1
|
| 1 |
IC50 = 695 nM
|
|
|
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CP0315726
|
3-ethyl-6-[2-(6-methylpyridin-2-yl)pyrazol-3-yl]quinazolin-4-one
Show/Hide
|
C19H17N5O
|
1
|
| 1 |
IC50 = 708 nM
|
|
|
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CP0572548
|
cyclopropyl-[3-[1-cyclopropyl-4-[2-[[2-(2-hydroxypropan-2-yl)pyridin-4-yl]amino]pyridin-4-yl]oxypyrazol-3-yl]azetidin-1-yl]methanone
Show/Hide
|
C26H30N6O3
|
1
|
| 1 |
IC50 = 748 nM
|
|
|
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CP0568823
|
N-[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]-2-[(3,5-dimethylmorpholin-4-yl)methyl]pyridin-4-amine
Show/Hide
|
C27H32F2N6O2
|
1
|
| 1 |
IC50 = 972 nM
|
|
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CP0356938
|
4-[1-cyclopropyl-4-[2-[[2-(2-hydroxypropan-2-yl)pyridin-4-yl]amino]pyridin-4-yl]oxypyrazol-3-yl]benzamide
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|
C26H26N6O3
|
1
|
| 1 |
IC50 = 2036 nM
|
|
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CP0568822
|
2-[4-[[4-[1-cyclopropyl-3-[1-(2,2,2-trifluoroethyl)azetidin-3-yl]pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
Show/Hide
|
C24H27F3N6O2
|
1
|
| 1 |
IC50 = 6689 nM
|
|
|
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CP0356939
|
2-[4-[[4-[1-cyclopropyl-3-(3,5-dimethyl-1,2-oxazol-4-yl)pyrazol-4-yl]oxypyridin-2-yl]amino]pyridin-2-yl]propan-2-ol
Show/Hide
|
C24H26N6O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
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CP0493067
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4-[1-cyclopropyl-4-[2-[[2-(2-hydroxypropan-2-yl)pyridin-4-yl]amino]pyridin-4-yl]oxypyrazol-3-yl]benzoic acid
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|
C26H25N5O4
|
1
|
| 1 |
IC50 > 10000 nM
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