General Information of the Compound
| Compound ID |
CP0356958
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N-[4-[1-cyclopropyl-3-(3,3-difluorocyclobutyl)pyrazol-4-yl]oxypyridin-2-yl]-2-morpholin-4-ylpyridin-4-amine
Show/Hide
|
||||||||||||||||||
| Formula |
C24H26F2N6O2
|
||||||||||||||||||
| Molecular Weight |
468.508
|
||||||||||||||||||
| Canonical SMILES |
FC1(F)CC(C1)c1nn(cc1Oc1ccnc(Nc2ccnc(c2)N2CCOCC2)c1)C1CC1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C24H26F2N6O2/c25-24(26)13-16(14-24)23-20(15-32(30-23)18-1-2-18)34-19-4-6-27-21(12-19)29-17-3-5-28-22(11-17)31-7-9-33-10-8-31/h3-6,11-12,15-16,18H,1-2,7-10,13-14H2,(H,27,28,29)
Show/Hide
|
||||||||||||||||||
| InChIKey |
HJALPQKWYFIRFF-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound