Brief Information of the Compound and Protein
Compound Name
4-[1-cyclopropyl-4-[2-[[2-(2-hydroxypropan-2-yl)pyridin-4-yl]amino]pyridin-4-yl]oxypyrazol-3-yl]-1-methylcyclohexan-1-ol
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PubChem ID
CID: 147473320
Canonical SMILES
CC(C)(O)c1cc(Nc2cc(Oc3cn(nc3C3CCC(C)(O)CC3)C3CC3)ccn2)ccn1
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Compound Formula C26H33N5O3
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q64729
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 136 nM
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