Brief Information of the Compound and Protein
Compound Name
4-[1-cyclopropyl-4-[2-[[2-(2-hydroxypropan-2-yl)pyridin-4-yl]amino]pyridin-4-yl]oxypyrazol-3-yl]benzoic acid
    Show/Hide
Canonical SMILES
CC(C)(O)c1cc(Nc2cc(Oc3cn(nc3-c3ccc(cc3)C(O)=O)C3CC3)ccn2)ccn1
    Show/Hide
Compound Formula C26H25N5O4
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q64729
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS