Compound ID |
Compound Name |
Compound Formula |
CP0412657
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]-8-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)quinazoline-2,4-diamine
Show/Hide
|
C25H27ClFN5
|
1
|
1 |
EC50 = 1100 nM
|
|
|
CP0412667
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]-8-(1,2,3,6-tetrahydropyridin-4-yl)quinazoline-2,4-diamine
Show/Hide
|
C24H25ClFN5
|
1
|
1 |
EC50 = 1800 nM
|
|
|
CP0471457
|
8-(azetidin-3-ylmethyl)-2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]quinazoline-2,4-diamine
Show/Hide
|
C23H25ClFN5
|
1
|
1 |
EC50 = 2000 nM
|
|
|
CP0412656
|
8-(aminomethyl)-2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]quinazoline-2,4-diamine
Show/Hide
|
C20H21ClFN5
|
1
|
1 |
EC50 = 2500 nM
|
|
|
CP0493021
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylbutyl]quinazoline-2,4-diamine
Show/Hide
|
C21H22ClFN4
|
1
|
1 |
EC50 = 2500 nM
|
|
|
CP0450621
|
8-(2-aminoethyl)-2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]quinazoline-2,4-diamine
Show/Hide
|
C21H23ClFN5
|
1
|
1 |
EC50 = 2700 nM
|
|
|
CP0536568
|
8-(azetidin-3-yl)-2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]quinazoline-2,4-diamine
Show/Hide
|
C22H23ClFN5
|
1
|
1 |
EC50 = 3000 nM
|
|
|
CP0519766
|
[(2S)-1-[6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-piperazin-1-ylbenzimidazol-4-yl]pyrrolidin-2-yl]methanamine
Show/Hide
|
C25H32ClFN6
|
1
|
1 |
EC50 = 3200 nM
|
|
|
CP0493022
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]-8-piperazin-1-ylquinazoline-2,4-diamine
Show/Hide
|
C23H26ClFN6
|
1
|
1 |
EC50 = 4200 nM
|
|
|
CP0387111
|
6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-4-(4-methylpiperazin-1-yl)benzimidazole
Show/Hide
|
C26H32ClFN6
|
1
|
1 |
EC50 = 5900 nM
|
|
|
CP0415807
|
6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-4-(4-methylpiperazin-1-yl)-2-piperazin-1-ylbenzimidazole
Show/Hide
|
C25H32ClFN6
|
1
|
1 |
EC50 = 6000 nM
|
|
|
CP0401722
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylpropyl]quinazoline-2,4-diamine
Show/Hide
|
C20H20ClFN4
|
1
|
1 |
EC50 = 6200 nM
|
|
|
CP0095962
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]quinazoline-2,4-diamine
Show/Hide
|
C19H18ClFN4
|
1
|
1 |
EC50 = 6400 nM
|
|
|
CP0536533
|
8-N-(2-aminoethyl)-2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]quinazoline-2,4,8-triamine
Show/Hide
|
C21H24ClFN6
|
1
|
1 |
EC50 = 6600 nM
|
|
|
CP0493019
|
2-N-(3-bromophenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C19H15BrN4O
|
1
|
1 |
EC50 = 7100 nM
|
|
|
CP0412664
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]-8-N-[2-(dimethylamino)ethyl]quinazoline-2,4,8-triamine
Show/Hide
|
C23H28ClFN6
|
1
|
1 |
EC50 = 7700 nM
|
|
|
CP0387110
|
5-[6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]benzimidazol-4-yl]-4-methylpyrimidin-2-amine
Show/Hide
|
C26H27ClFN7
|
1
|
1 |
EC50 = 7800 nM
|
|
|
CP0429954
|
6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-piperazin-1-yl-4-(4-propan-2-ylpyrimidin-5-yl)benzimidazole
Show/Hide
|
C27H30ClFN6
|
1
|
1 |
EC50 = 8800 nM
|
|
|
CP0405322
|
6-chloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-piperazin-1-ylbenzimidazole
Show/Hide
|
C25H28ClFN6
|
1
|
1 |
EC50 = 9000 nM
|
|
|
CP0412659
|
2-N-(3-chlorophenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C19H15ClN4O
|
1
|
1 |
EC50 = 9700 nM
|
|
|
CP0410993
|
6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-4-(4-methylpyrimidin-5-yl)-2-piperazin-1-ylbenzimidazole
Show/Hide
|
C25H26ClFN6
|
1
|
1 |
EC50 = 10200 nM
|
|
|
CP0387116
|
6-chloro-4-(2-chlorophenyl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-piperazin-1-ylbenzimidazole
Show/Hide
|
C26H25Cl2FN4
|
1
|
1 |
EC50 = 11000 nM
|
|
|
CP0410994
|
6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-4-(4-methylpyrimidin-5-yl)benzimidazole
Show/Hide
|
C26H26ClFN6
|
1
|
1 |
EC50 = 11400 nM
|
|
|
CP0412653
|
2-N-(3-chloro-4-fluorophenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C19H14ClFN4O
|
1
|
1 |
EC50 = 13100 nM
|
|
|
CP0405324
|
5-[6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluorophenyl)methyl]benzimidazol-4-yl]-4-methylpyrimidin-2-amine
Show/Hide
|
C24H23ClFN7
|
1
|
1 |
EC50 = 14000 nM
|
|
|
CP0410992
|
6-chloro-4-(2-chlorophenyl)-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]benzimidazole
Show/Hide
|
C27H25Cl2FN4
|
1
|
1 |
EC50 = 14000 nM
|
|
|
CP0387112
|
6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-4-(3,5-dimethyl-1H-pyrazol-4-yl)-1-[(4-fluoro-3,5-dimethylphenyl)methyl]benzimidazole
Show/Hide
|
C26H28ClFN6
|
1
|
1 |
EC50 = 14100 nM
|
|
|
CP0387115
|
6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-piperazin-1-ylbenzimidazole
Show/Hide
|
C20H22ClFN4
|
1
|
1 |
EC50 = 14500 nM
|
|
|
CP0401721
|
2-N-(3-chloro-4-fluorophenyl)-4-N-(cyclopropylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C18H16ClFN4
|
1
|
1 |
EC50 = 16300 nM
|
|
|
CP0412651
|
2-furfuryl-[2-(m-toluidino)quinazolin-4-yl]amine;hydrochloride
Show/Hide
|
C20H18N4O
|
1
|
1 |
EC50 = 16400 nM
|
|
|
CP0387114
|
1-[(3-chloro-4-fluorophenyl)methyl]-2-piperazin-1-ylbenzimidazole
Show/Hide
|
C18H18ClFN4
|
1
|
1 |
EC50 = 21000 nM
|
|
|
CP0405321
|
1-[(3-chloro-4-fluorophenyl)methyl]-5,6-dimethyl-2-piperazin-1-ylbenzimidazole
Show/Hide
|
C20H22ClFN4
|
1
|
1 |
EC50 = 21300 nM
|
|
|
CP0471455
|
2-N-(3-chloro-4-fluorophenyl)-4-N-pentan-3-ylquinazoline-2,4-diamine
Show/Hide
|
C19H20ClFN4
|
1
|
1 |
EC50 = 21900 nM
|
|
|
CP0387118
|
1-[(3-chloro-4-fluorophenyl)methyl]-5,6-dimethylbenzimidazol-2-amine
Show/Hide
|
C16H15ClFN3
|
1
|
1 |
EC50 = 32200 nM
|
|
|
CP0387117
|
6-chloro-2-(2,6-diazaspiro[3.3]heptan-2-yl)-1-[(4-fluorophenyl)methyl]-4-(4-methylpyrimidin-5-yl)benzimidazole
Show/Hide
|
C24H22ClFN6
|
1
|
1 |
EC50 = 33200 nM
|
|
|
CP0412655
|
2-N-(3-chloro-4-fluorophenyl)-4-N-(cyclobutylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C19H18ClFN4
|
1
|
1 |
EC50 = 44200 nM
|
|
|
CP0401719
|
2-N-(4-bromophenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C19H15BrN4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0412652
|
2-N-(3,5-dichlorophenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C19H14Cl2N4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0412654
|
N-[2-(3-chloro-4-fluoroanilino)quinazolin-4-yl]-N-(furan-2-ylmethyl)acetamide
Show/Hide
|
C21H16ClFN4O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0412658
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]-8-morpholin-4-ylquinazoline-2,4-diamine
Show/Hide
|
C23H25ClFN5O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0412660
|
(2-anilinoquinazolin-4-yl)-(2-furfuryl)amine;hydrochloride
Show/Hide
|
C19H16N4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0412662
|
2-N-(3,5-dimethylphenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C21H20N4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0412663
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclobutylpropyl]quinazoline-2,4-diamine
Show/Hide
|
C21H22ClFN4
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0450622
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]-8-(2-ethoxyethyl)quinazoline-2,4-diamine
Show/Hide
|
C23H26ClFN4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0450623
|
2-N-(3,4-dichlorophenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C19H14Cl2N4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0450626
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclobutylethyl]quinazoline-2,4-diamine
Show/Hide
|
C20H20ClFN4
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0458078
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropyl-3-methylbutyl]quinazoline-2,4-diamine
Show/Hide
|
C22H24ClFN4
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0458080
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1S)-1-cyclopropylethyl]quinazoline-2,4-diamine
Show/Hide
|
C19H18ClFN4
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0466679
|
2-furfuryl-[2-(p-toluidino)quinazolin-4-yl]amine;hydrochloride
Show/Hide
|
C20H18N4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0471454
|
1-[3-[[4-(furan-2-ylmethylamino)quinazolin-2-yl]amino]phenyl]ethanol
Show/Hide
|
C21H20N4O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0471456
|
2-N-(3-chloro-4-fluorophenyl)-4-N-(2-methylpropyl)quinazoline-2,4-diamine
Show/Hide
|
C18H18ClFN4
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0471458
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1R)-1-cyclopropylethyl]-8-(3,6-dihydro-2H-pyran-4-yl)quinazoline-2,4-diamine
Show/Hide
|
C24H24ClFN4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0472108
|
2-[[2-(3-chloro-4-fluoroanilino)-4-[[(1R)-1-cyclopropylethyl]amino]quinazolin-8-yl]amino]ethanol
Show/Hide
|
C21H23ClFN5O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0472110
|
4-N-(furan-2-ylmethyl)-2-N-(4-methoxyphenyl)quinazoline-2,4-diamine
Show/Hide
|
C20H18N4O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0493018
|
2-N-(3-chloro-4-fluorophenyl)-4-N-ethyl-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C21H18ClFN4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0530536
|
4-N-(furan-2-ylmethyl)-2-N-(3-methoxyphenyl)quinazoline-2,4-diamine
Show/Hide
|
C20H18N4O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0536529
|
2-N-(3,4-dimethylphenyl)-4-N-(furan-2-ylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C21H20N4O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0536531
|
2-N-(3-chloro-4-fluorophenyl)-4-N-(cyclopentylmethyl)quinazoline-2,4-diamine
Show/Hide
|
C20H20ClFN4
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0536532
|
2-N-(3-chloro-4-fluorophenyl)-4-N-[(1S)-1-cyclopropylpropyl]quinazoline-2,4-diamine
Show/Hide
|
C20H20ClFN4
|
1
|
1 |
EC50 > 100000 nM
|
|
|