Brief Information of the Compound and Protein
Compound Name
6-chloro-1-[(4-fluoro-3,5-dimethylphenyl)methyl]-2-piperazin-1-yl-4-(4-propan-2-ylpyrimidin-5-yl)benzimidazole
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PubChem ID
CID: 145966464
Canonical SMILES
CC(C)c1ncncc1-c1cc(Cl)cc2n(Cc3cc(C)c(F)c(C)c3)c(nc12)N1CCNCC1
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Compound Formula C27H30ClFN6
Compound Structure
Protein Name
Son of sevenless homolog 1
Protein Classification
Unclassified protein
Uniprot ID
Q07889
Gene Name
SOS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 8800 nM
   TI
   LI
   LO
   TS
CL000654 NCI-H727 Homo sapiens (Human)  1
1
EC50 = 13900 nM
   TI
   LI
   LO
   TS